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Items: 1 to 20 of 213


CagA phosphorylation-dependent MMP-9 expression in gastric epithelial cells.

Nam YH, Ryu E, Lee D, Shim HJ, Lee YC, Lee ST.

Helicobacter. 2011 Aug;16(4):276-83. doi: 10.1111/j.1523-5378.2011.00851.x.


Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation.

Pillinger MH, Marjanovic N, Kim SY, Lee YC, Scher JU, Roper J, Abeles AM, Izmirly PI, Axelrod M, Pillinger MY, Tolani S, Dinsell V, Abramson SB, Blaser MJ.

J Biol Chem. 2007 Jun 29;282(26):18722-31. Epub 2007 May 2.


Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.

Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M.

J Biol Chem. 2004 Apr 23;279(17):17205-16. Epub 2004 Feb 12.


Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA.

Naito M, Yamazaki T, Tsutsumi R, Higashi H, Onoe K, Yamazaki S, Azuma T, Hatakeyama M.

Gastroenterology. 2006 Apr;130(4):1181-90.


Helicobacter pylori CagA protein induces factors involved in the epithelial to mesenchymal transition (EMT) in infected gastric epithelial cells in an EPIYA- phosphorylation-dependent manner.

Sougleri IS, Papadakos KS, Zadik MP, Mavri-Vavagianni M, Mentis AF, Sgouras DN.

FEBS J. 2016 Jan;283(2):206-20. doi: 10.1111/febs.13592. Epub 2015 Dec 11.


Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering.

Tammer I, Brandt S, Hartig R, König W, Backert S.

Gastroenterology. 2007 Apr;132(4):1309-19. Epub 2007 Feb 1.


The effects of cure of Helicobacter pylori infection on the signal transduction of gastric epithelial cells.

Azuma T, Yamazaki S, Yamakawa A, Ito Y, Ohtani M, Dojo M, Yamazaki Y, Higashi H, Hatakeyama M.

Aliment Pharmacol Ther. 2003 Jul;18 Suppl 1:39-44.


Interaction between the Helicobacter pylori CagA and alpha-Pix in gastric epithelial AGS cells.

Baek HY, Lim JW, Kim H.

Ann N Y Acad Sci. 2007 Jan;1096:18-23.


Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells.

Ren S, Higashi H, Lu H, Azuma T, Hatakeyama M.

J Biol Chem. 2006 Oct 27;281(43):32344-52. Epub 2006 Sep 5.


Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA.

Tsutsumi R, Takahashi A, Azuma T, Higashi H, Hatakeyama M.

Mol Cell Biol. 2006 Jan;26(1):261-76.


EPIYA motif is a membrane-targeting signal of Helicobacter pylori virulence factor CagA in mammalian cells.

Higashi H, Yokoyama K, Fujii Y, Ren S, Yuasa H, Saadat I, Murata-Kamiya N, Azuma T, Hatakeyama M.

J Biol Chem. 2005 Jun 17;280(24):23130-7. Epub 2005 Apr 13.


Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERK pathways.

Zhao D, Liu Z, Ding J, Li W, Sun Y, Yu H, Zhou Y, Zeng J, Chen C, Jia J.

J Med Microbiol. 2010 Mar;59(Pt 3):259-65. doi: 10.1099/jmm.0.014704-0. Epub 2009 Dec 3.


The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa.

Yamazaki S, Yamakawa A, Ito Y, Ohtani M, Higashi H, Hatakeyama M, Azuma T.

J Infect Dis. 2003 Jan 15;187(2):334-7. Epub 2002 Dec 19.


The genome-wide expression profile of gastric epithelial cells infected by naturally occurring cagA isogenic strains of Helicobacter pylori.

Sohn SH, Lee YC.

Environ Toxicol Pharmacol. 2011 Nov;32(3):382-9. doi: 10.1016/j.etap.2011.08.006. Epub 2011 Aug 16.


Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.

Lee KS, Kalantzis A, Jackson CB, O'Connor L, Murata-Kamiya N, Hatakeyama M, Judd LM, Giraud AS, Menheniott TR.

PLoS One. 2012;7(2):e30786. doi: 10.1371/journal.pone.0030786. Epub 2012 Feb 1.


Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase.

Tsutsumi R, Higashi H, Higuchi M, Okada M, Hatakeyama M.

J Biol Chem. 2003 Feb 7;278(6):3664-70. Epub 2002 Nov 21.


Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion.

Suzuki M, Mimuro H, Suzuki T, Park M, Yamamoto T, Sasakawa C.

J Exp Med. 2005 Nov 7;202(9):1235-47.


Heterogeneity in the activity of Mexican Helicobacter pylori strains in gastric epithelial cells and its association with diversity in the cagA gene.

Reyes-Leon A, Atherton JC, Argent RH, Puente JL, Torres J.

Infect Immun. 2007 Jul;75(7):3445-54. Epub 2007 Apr 16.


Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori.

Argent RH, Kidd M, Owen RJ, Thomas RJ, Limb MC, Atherton JC.

Gastroenterology. 2004 Aug;127(2):514-23.


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