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Items: 1 to 20 of 118

1.

Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis.

Marquis JF, Kapoustina O, Langlais D, Ruddy R, Dufour CR, Kim BH, MacMicking JD, Giguère V, Gros P.

PLoS Genet. 2011 Jun;7(6):e1002097. doi: 10.1371/journal.pgen.1002097. Epub 2011 Jun 23.

2.

Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.

Berghout J, Langlais D, Radovanovic I, Tam M, MacMicking JD, Stevenson MM, Gros P.

PLoS Pathog. 2013;9(7):e1003491. doi: 10.1371/journal.ppat.1003491. Epub 2013 Jul 11. Erratum in: PLoS Pathog. 2015 Mar;11(3):e1004719.

3.

Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation.

Smith MA, Wright G, Wu J, Tailor P, Ozato K, Chen X, Wei S, Piskurich JF, Ting JP, Wright KL.

J Biol Chem. 2011 Mar 11;286(10):7893-904. doi: 10.1074/jbc.M110.165431. Epub 2011 Jan 7.

4.
5.

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells.

Kubosaki A, Lindgren G, Tagami M, Simon C, Tomaru Y, Miura H, Suzuki T, Arner E, Forrest AR, Irvine KM, Schroder K, Hasegawa Y, Kanamori-Katayama M, Rehli M, Hume DA, Kawai J, Suzuki M, Suzuki H, Hayashizaki Y.

Mol Immunol. 2010 Aug;47(14):2295-302. doi: 10.1016/j.molimm.2010.05.289. Epub 2010 Jun 22.

PMID:
20573402
6.

Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis.

Carow B, Reuschl AK, Gavier-Widén D, Jenkins BJ, Ernst M, Yoshimura A, Chambers BJ, Rottenberg ME.

PLoS Pathog. 2013;9(7):e1003442. doi: 10.1371/journal.ppat.1003442. Epub 2013 Jul 4.

7.

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.

Langlais D, Barreiro LB, Gros P.

J Exp Med. 2016 Apr 4;213(4):585-603. doi: 10.1084/jem.20151764. Epub 2016 Mar 21.

8.

Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4.

Fortier A, Doiron K, Saleh M, Grinstein S, Gros P.

Infect Immun. 2009 Nov;77(11):4794-805. doi: 10.1128/IAI.01546-08. Epub 2009 Aug 31.

9.

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation.

Kurotaki D, Osato N, Nishiyama A, Yamamoto M, Ban T, Sato H, Nakabayashi J, Umehara M, Miyake N, Matsumoto N, Nakazawa M, Ozato K, Tamura T.

Blood. 2013 Mar 7;121(10):1839-49. doi: 10.1182/blood-2012-06-437863. Epub 2013 Jan 14.

10.

Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis.

Ottenhoff TH, Dass RH, Yang N, Zhang MM, Wong HE, Sahiratmadja E, Khor CC, Alisjahbana B, van Crevel R, Marzuki S, Seielstad M, van de Vosse E, Hibberd ML.

PLoS One. 2012;7(9):e45839. doi: 10.1371/journal.pone.0045839. Epub 2012 Sep 21.

11.

Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8.

Marquis JF, LaCourse R, Ryan L, North RJ, Gros P.

J Immunol. 2009 Mar 1;182(5):3008-15. doi: 10.4049/jimmunol.0800680.

12.

IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes.

Gupta M, Shin DM, Ramakrishna L, Goussetis DJ, Platanias LC, Xiong H, Morse HC 3rd, Ozato K.

Nat Commun. 2015 Mar 16;6:6379. doi: 10.1038/ncomms7379.

13.

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation.

Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H.

Nat Immunol. 2014 Feb;15(2):161-7. doi: 10.1038/ni.2795. Epub 2013 Dec 22.

PMID:
24362890
15.

Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection.

Yan M, Wang H, Sun J, Liao W, Li P, Zhu Y, Xu C, Joo J, Sun Y, Abbasi S, Kovalchuk A, Lv N, Leonard WJ, Morse HC 3rd.

J Immunol. 2016 Mar 1;196(5):1999-2003. doi: 10.4049/jimmunol.1500766. Epub 2016 Feb 3.

16.

Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein.

Lee CH, Melchers M, Wang H, Torrey TA, Slota R, Qi CF, Kim JY, Lugar P, Kong HJ, Farrington L, van der Zouwen B, Zhou JX, Lougaris V, Lipsky PE, Grammer AC, Morse HC 3rd.

J Exp Med. 2006 Jan 23;203(1):63-72. Epub 2005 Dec 27. Erratum in: J Exp Med. 2008 Jun 9;205(6):1507. J Exp Med. 2006 Feb 20;203(2):475.

17.

Suboptimal Antigen Presentation Contributes to Virulence of Mycobacterium tuberculosis In Vivo.

Grace PS, Ernst JD.

J Immunol. 2016 Jan 1;196(1):357-64. doi: 10.4049/jimmunol.1501494. Epub 2015 Nov 16.

18.

The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription.

Simon PS, Sharman SK, Lu C, Yang D, Paschall AV, Tulachan SS, Liu K.

BMC Cancer. 2015 Oct 23;15:770. doi: 10.1186/s12885-015-1808-6.

19.

Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development.

Yamamoto M, Kato T, Hotta C, Nishiyama A, Kurotaki D, Yoshinari M, Takami M, Ichino M, Nakazawa M, Matsuyama T, Kamijo R, Kitagawa S, Ozato K, Tamura T.

PLoS One. 2011;6(10):e25812. doi: 10.1371/journal.pone.0025812. Epub 2011 Oct 7.

20.

IRF8 and IRF3 cooperatively regulate rapid interferon-β induction in human blood monocytes.

Li P, Wong JJ, Sum C, Sin WX, Ng KQ, Koh MB, Chin KC.

Blood. 2011 Mar 10;117(10):2847-54. doi: 10.1182/blood-2010-07-294272. Epub 2011 Jan 12.

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