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The NS1 protein of influenza A virus interacts with heat shock protein Hsp90 in human alveolar basal epithelial cells: implication for virus-induced apoptosis.

Zhang C, Yang Y, Zhou X, Yang Z, Liu X, Cao Z, Song H, He Y, Huang P.

Virol J. 2011 Apr 19;8:181. doi: 10.1186/1743-422X-8-181.


Highly pathogenic avian influenza A virus H5N1 NS1 protein induces caspase-dependent apoptosis in human alveolar basal epithelial cells.

Zhang C, Yang Y, Zhou X, Liu X, Song H, He Y, Huang P.

Virol J. 2010 Mar 3;7:51. doi: 10.1186/1743-422X-7-51.


Avian influenza virus A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells.

Lam WY, Tang JW, Yeung AC, Chiu LC, Sung JJ, Chan PK.

J Virol. 2008 Mar;82(6):2741-51. doi: 10.1128/JVI.01712-07. Epub 2008 Jan 16.


Direct interaction of cellular hnRNP-F and NS1 of influenza A virus accelerates viral replication by modulation of viral transcriptional activity and host gene expression.

Lee JH, Kim SH, Pascua PN, Song MS, Baek YH, Jin X, Choi JK, Kim CJ, Kim H, Choi YK.

Virology. 2010 Feb 5;397(1):89-99. doi: 10.1016/j.virol.2009.10.041. Epub 2009 Nov 18. Retraction in: Virology. 2013 Feb 5;436(1):245.


Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin.

Melén K, Tynell J, Fagerlund R, Roussel P, Hernandez-Verdun D, Julkunen I.

Virol J. 2012 Aug 21;9:167. doi: 10.1186/1743-422X-9-167.


Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains.

Li W, Zhang H, Wang G, Zhang C, Zeng X, Liu H, Chen X, Xu Y, Li K.

Sci China Life Sci. 2012 Jun;55(6):507-15. doi: 10.1007/s11427-012-4335-6. Epub 2012 Jun 29.


Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses.

Ehrhardt C, Wolff T, Pleschka S, Planz O, Beermann W, Bode JG, Schmolke M, Ludwig S.

J Virol. 2007 Apr;81(7):3058-67. Epub 2007 Jan 17.


PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.

Yu J, Li X, Wang Y, Li B, Li H, Li Y, Zhou W, Zhang C, Wang Y, Rao Z, Bartlam M, Cao Y.

PLoS One. 2011;6(5):e19511. doi: 10.1371/journal.pone.0019511. Epub 2011 May 23.


Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.

Zielecki F, Semmler I, Kalthoff D, Voss D, Mauel S, Gruber AD, Beer M, Wolff T.

J Virol. 2010 Oct;84(20):10708-18. doi: 10.1128/JVI.00610-10. Epub 2010 Aug 4.


Non structural protein of avian influenza A (H11N1) virus is a weaker suppressor of immune responses but capable of inducing apoptosis in host cells.

Mukherjee S, Majumdar S, Vipat VC, Mishra AC, Chakrabarti AK.

Virol J. 2012 Aug 6;9:149. doi: 10.1186/1743-422X-9-149.


Interaction of avian influenza virus NS1 protein and nucleolar and coiled-body phosphoprotein 1.

Zhu C, Zheng F, Sun T, Duan Y, Cao J, Feng H, Shang L, Zhu Y, Liu H.

Virus Genes. 2013 Apr;46(2):287-92. doi: 10.1007/s11262-012-0849-z. Epub 2012 Nov 28.


A new panel of NS1 antibodies for easy detection and titration of influenza A virus.

Tan Z, Akerstrom S, Wee BY, Lal SK, Mirazimi A, Tan YJ.

J Med Virol. 2010 Mar;82(3):467-75. doi: 10.1002/jmv.21709.


The distinct binding properties between avian/human influenza A virus NS1 and Postsynaptic density protein-95 (PSD-95), and inhibition of nitric oxide production.

Zhang H, Li W, Wang G, Su Y, Zhang C, Chen X, Xu Y, Li K.

Virol J. 2011 Jun 13;8:298. doi: 10.1186/1743-422X-8-298.


DDX3 Interacts with Influenza A Virus NS1 and NP Proteins and Exerts Antiviral Function through Regulation of Stress Granule Formation.

Thulasi Raman SN, Liu G, Pyo HM, Cui YC, Xu F, Ayalew LE, Tikoo SK, Zhou Y.

J Virol. 2016 Jan 20;90(7):3661-75. doi: 10.1128/JVI.03010-15.


Synergistic effect of the PDZ and p85β-binding domains of the NS1 protein on virulence of an avian H5N1 influenza A virus.

Fan S, Macken CA, Li C, Ozawa M, Goto H, Iswahyudi NF, Nidom CA, Chen H, Neumann G, Kawaoka Y.

J Virol. 2013 May;87(9):4861-71. doi: 10.1128/JVI.02608-12. Epub 2013 Feb 13.


Influenza virus A/Beijing/501/2009(H1N1) NS1 interacts with β-tubulin and induces disruption of the microtubule network and apoptosis on A549 cells.

Han X, Li Z, Chen H, Wang H, Mei L, Wu S, Zhang T, Liu B, Lin X.

PLoS One. 2012;7(11):e48340. doi: 10.1371/journal.pone.0048340. Epub 2012 Nov 6.


Modification of nonstructural protein 1 of influenza A virus by SUMO1.

Xu K, Klenk C, Liu B, Keiner B, Cheng J, Zheng BJ, Li L, Han Q, Wang C, Li T, Chen Z, Shu Y, Liu J, Klenk HD, Sun B.

J Virol. 2011 Jan;85(2):1086-98. doi: 10.1128/JVI.00877-10. Epub 2010 Nov 3.


Influenza A virus NS1 induces G0/G1 cell cycle arrest by inhibiting the expression and activity of RhoA protein.

Jiang W, Wang Q, Chen S, Gao S, Song L, Liu P, Huang W.

J Virol. 2013 Mar;87(6):3039-52. doi: 10.1128/JVI.03176-12. Epub 2013 Jan 2.

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