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Items: 1 to 20 of 79

1.

c-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: a prerequisite for replication.

Pfannkuche A, Büther K, Karthe J, Poenisch M, Bartenschlager R, Trilling M, Hengel H, Willbold D, Häussinger D, Bode JG.

Hepatology. 2011 Apr;53(4):1127-36. doi: 10.1002/hep.24214.

PMID:
21480319
2.

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.

Hamamoto I, Nishimura Y, Okamoto T, Aizaki H, Liu M, Mori Y, Abe T, Suzuki T, Lai MM, Miyamura T, Moriishi K, Matsuura Y.

J Virol. 2005 Nov;79(21):13473-82.

3.

The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity.

Macdonald A, Crowder K, Street A, McCormick C, Harris M.

J Gen Virol. 2004 Mar;85(Pt 3):721-9.

PMID:
14993658
4.

Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling.

Macdonald A, Mazaleyrat S, McCormick C, Street A, Burgoyne NJ, Jackson RM, Cazeaux V, Shelton H, Saksela K, Harris M.

J Gen Virol. 2005 Apr;86(Pt 4):1035-44.

PMID:
15784897
5.

Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90.

Okamoto T, Nishimura Y, Ichimura T, Suzuki K, Miyamura T, Suzuki T, Moriishi K, Matsuura Y.

EMBO J. 2006 Oct 18;25(20):5015-25. Epub 2006 Oct 5. Erratum in: EMBO J. 2006 Nov 29;25(23):5634.

6.

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein.

Tu H, Gao L, Shi ST, Taylor DR, Yang T, Mircheff AK, Wen Y, Gorbalenya AE, Hwang SB, Lai MM.

Virology. 1999 Oct 10;263(1):30-41.

7.

Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.

Xiong W, Yang J, Wang M, Wang H, Rao Z, Zhong C, Xin X, Mo L, Yu S, Shen C, Zheng C.

J Virol. 2015 Jul;89(14):7385-400. doi: 10.1128/JVI.00567-15. Epub 2015 May 13.

8.

Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

Appel N, Zayas M, Miller S, Krijnse-Locker J, Schaller T, Friebe P, Kallis S, Engel U, Bartenschlager R.

PLoS Pathog. 2008 Mar 28;4(3):e1000035. doi: 10.1371/journal.ppat.1000035.

9.

Human Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation.

Wong MT, Chen SS.

J Virol. 2016 Sep 29;90(20):9075-95. doi: 10.1128/JVI.00960-16. Print 2016 Oct 15.

10.

Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication.

Bürckstümmer T, Kriegs M, Lupberger J, Pauli EK, Schmittel S, Hildt E.

FEBS Lett. 2006 Jan 23;580(2):575-80. Epub 2005 Dec 29.

11.

Dominant negative effect of wild-type NS5A on NS5A-adapted subgenomic hepatitis C virus RNA replicon.

Graziani R, Paonessa G.

J Gen Virol. 2004 Jul;85(Pt 7):1867-75.

PMID:
15218171
12.

Characterization of the interaction between hepatitis C virus NS5B and the human oestrogen receptor alpha.

Hillung J, Ruiz-López E, Bellón-Echeverría I, Clemente-Casares P, Mas A.

J Gen Virol. 2012 Apr;93(Pt 4):780-5. doi: 10.1099/vir.0.039396-0. Epub 2011 Dec 14.

PMID:
22170636
13.

The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein.

Martin-Garcia JM, Luque I, Ruiz-Sanz J, Camara-Artigas A.

Acta Crystallogr D Biol Crystallogr. 2012 Aug;68(Pt 8):1030-40. doi: 10.1107/S0907444912019798. Epub 2012 Jul 17.

PMID:
22868769
14.

Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

Huang Y, Staschke K, De Francesco R, Tan SL.

Virology. 2007 Jul 20;364(1):1-9. Epub 2007 Apr 2. Review.

15.

Regulation of hepatitis C virion production via phosphorylation of the NS5A protein.

Tellinghuisen TL, Foss KL, Treadaway J.

PLoS Pathog. 2008 Mar 21;4(3):e1000032. doi: 10.1371/journal.ppat.1000032.

16.

Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A.

Chen YC, Su WC, Huang JY, Chao TC, Jeng KS, Machida K, Lai MM.

J Virol. 2010 Aug;84(16):7983-93. doi: 10.1128/JVI.00068-10. Epub 2010 Jun 9.

18.

Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication.

Klinker S, Stindt S, Gremer L, Bode JG, Gertzen CGW, Gohlke H, Weiergräber OH, Hoffmann S, Willbold D.

J Biol Chem. 2019 May 3;294(18):7388-7402. doi: 10.1074/jbc.RA119.007656. Epub 2019 Mar 12.

PMID:
30862675
19.

Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity.

Shirota Y, Luo H, Qin W, Kaneko S, Yamashita T, Kobayashi K, Murakami S.

J Biol Chem. 2002 Mar 29;277(13):11149-55. Epub 2002 Jan 18.

20.

Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein.

Inoue Y, Aizaki H, Hara H, Matsuda M, Ando T, Shimoji T, Murakami K, Masaki T, Shoji I, Homma S, Matsuura Y, Miyamura T, Wakita T, Suzuki T.

Virology. 2011 Feb 5;410(1):38-47. doi: 10.1016/j.virol.2010.10.026. Epub 2010 Nov 18.

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