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Items: 1 to 20 of 95

1.

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples.

Ackerman ME, Moldt B, Wyatt RT, Dugast AS, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G.

J Immunol Methods. 2011 Mar 7;366(1-2):8-19. doi: 10.1016/j.jim.2010.12.016. Epub 2010 Dec 27. Erratum in: J Immunol Methods. 2012 Feb 28;376(1-2):156.

2.

Determining the phagocytic activity of clinical antibody samples.

McAndrew EG, Dugast AS, Licht AF, Eusebio JR, Alter G, Ackerman ME.

J Vis Exp. 2011 Nov 30;(57):e3588. doi: 10.3791/3588.

3.

Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles.

Brown EP, Dowell KG, Boesch AW, Normandin E, Mahan AE, Chu T, Barouch DH, Bailey-Kellogg C, Alter G, Ackerman ME.

J Immunol Methods. 2017 Apr;443:33-44. doi: 10.1016/j.jim.2017.01.010. Epub 2017 Feb 3.

4.

IgG2 inhibits HIV-1 internalization by monocytes, and IgG subclass binding is affected by gp120 glycosylation.

Forthal DN, Landucci G, Ding H, Kappes JC, Wang A, Thung I, Phan T.

AIDS. 2011 Nov 13;25(17):2099-104. doi: 10.1097/QAD.0b013e32834b64bd.

PMID:
21832933
5.

Antibody Functional Assays as Measures of Fc Receptor-Mediated Immunity to HIV - New Technologies and their Impact on the HIV Vaccine Field.

Wines BD, Billings H, Mclean MR, Kent SJ, Hogarth PM.

Curr HIV Res. 2017;15(3):202-215. doi: 10.2174/1570162X15666170320112247. Review.

6.

Using an improved phagocytosis assay to evaluate the effect of HIV on specific antibodies to pregnancy-associated malaria.

Ataíde R, Hasang W, Wilson DW, Beeson JG, Mwapasa V, Molyneux ME, Meshnick SR, Rogerson SJ.

PLoS One. 2010 May 25;5(5):e10807. doi: 10.1371/journal.pone.0010807.

7.

Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b.

Ackerman ME, Dugast AS, McAndrew EG, Tsoukas S, Licht AF, Irvine DJ, Alter G.

J Virol. 2013 May;87(10):5468-76. doi: 10.1128/JVI.03403-12. Epub 2013 Mar 6.

8.

Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.

Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, Alter G.

PLoS Pathog. 2016 Mar 16;12(3):e1005456. doi: 10.1371/journal.ppat.1005456. eCollection 2016 Mar. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005694.

9.

Dengue virus neutralization in cells expressing Fc gamma receptors.

Chawla T, Chan KR, Zhang SL, Tan HC, Lim AP, Hanson BJ, Ooi EE.

PLoS One. 2013 May 22;8(5):e65231. doi: 10.1371/journal.pone.0065231. Print 2013.

10.

CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor- and Complement Receptor 3-Dependent Mechanisms.

Amash A, Wang L, Wang Y, Bhakta V, Fairn GD, Hou M, Peng J, Sheffield WP, Lazarus AH.

J Immunol. 2016 Apr 15;196(8):3331-40. doi: 10.4049/jimmunol.1502198. Epub 2016 Mar 4.

11.

Correlation of ADCC activity with cytokine release induced by the stably expressed, glyco-engineered humanized Lewis Y-specific monoclonal antibody MB314.

Kircheis R, Halanek N, Koller I, Jost W, Schuster M, Gorr G, Hajszan K, Nechansky A.

MAbs. 2012 Jul-Aug;4(4):532-41. doi: 10.4161/mabs.20577. Epub 2012 Jul 1.

12.

Novel drug and soluble target tolerant antidrug antibody assay for therapeutic antibodies bearing the P329G mutation.

Wessels U, Schick E, Ritter M, Kowalewsky F, Heinrich J, Stubenrauch K.

Bioanalysis. 2017 Jun;9(11):849-859. doi: 10.4155/bio-2017-0048. Epub 2017 May 18.

13.

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.

Vafa O, Gilliland GL, Brezski RJ, Strake B, Wilkinson T, Lacy ER, Scallon B, Teplyakov A, Malia TJ, Strohl WR.

Methods. 2014 Jan 1;65(1):114-26. doi: 10.1016/j.ymeth.2013.06.035. Epub 2013 Jul 17.

PMID:
23872058
14.

Aglycosylated IgG variants expressed in bacteria that selectively bind FcgammaRI potentiate tumor cell killing by monocyte-dendritic cells.

Jung ST, Reddy ST, Kang TH, Borrok MJ, Sandlie I, Tucker PW, Georgiou G.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):604-9. doi: 10.1073/pnas.0908590107. Epub 2009 Dec 18.

15.

Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity.

Ackerman ME, Crispin M, Yu X, Baruah K, Boesch AW, Harvey DJ, Dugast AS, Heizen EL, Ercan A, Choi I, Streeck H, Nigrovic PA, Bailey-Kellogg C, Scanlan C, Alter G.

J Clin Invest. 2013 May;123(5):2183-92. doi: 10.1172/JCI65708. Epub 2013 Apr 8.

16.

Phagocytosis stimulates mobilization and shedding of intracellular CD16A in human monocytes and macrophages: inhibition by HIV-1 infection.

Webster NL, Kedzierska K, Azzam R, Paukovics G, Wilson J, Crowe SM, Jaworowski A.

J Leukoc Biol. 2006 Feb;79(2):294-302. Epub 2005 Nov 21.

PMID:
16301325
17.

HIV-specific antibody immunity mediated through NK cells and monocytes.

Kramski M, Parsons MS, Stratov I, Kent SJ.

Curr HIV Res. 2013 Jul;11(5):388-406. Review.

PMID:
24191935
18.

Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding.

Borrok MJ, Luheshi NM, Beyaz N, Davies GC, Legg JW, Wu H, Dall'Acqua WF, Tsui P.

MAbs. 2015;7(4):743-51. doi: 10.1080/19420862.2015.1047570.

19.

Plasmablast-derived polyclonal antibody response after influenza vaccination.

He XS, Sasaki S, Narvaez CF, Zhang C, Liu H, Woo JC, Kemble GW, Dekker CL, Davis MM, Greenberg HB.

J Immunol Methods. 2011 Feb 28;365(1-2):67-75. doi: 10.1016/j.jim.2010.12.008. Epub 2010 Dec 21.

20.

A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV.

Moldt B, Schultz N, Dunlop DC, Alpert MD, Harvey JD, Evans DT, Poignard P, Hessell AJ, Burton DR.

J Virol. 2011 Oct;85(20):10572-81. doi: 10.1128/JVI.05541-11. Epub 2011 Aug 17.

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