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Items: 1 to 20 of 170

1.

Modification of nonstructural protein 1 of influenza A virus by SUMO1.

Xu K, Klenk C, Liu B, Keiner B, Cheng J, Zheng BJ, Li L, Han Q, Wang C, Li T, Chen Z, Shu Y, Liu J, Klenk HD, Sun B.

J Virol. 2011 Jan;85(2):1086-98. doi: 10.1128/JVI.00877-10. Epub 2010 Nov 3.

2.

A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity.

Jackson D, Hossain MJ, Hickman D, Perez DR, Lamb RA.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4381-6. doi: 10.1073/pnas.0800482105. Epub 2008 Mar 11.

3.

Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.

Zielecki F, Semmler I, Kalthoff D, Voss D, Mauel S, Gruber AD, Beer M, Wolff T.

J Virol. 2010 Oct;84(20):10708-18. doi: 10.1128/JVI.00610-10. Epub 2010 Aug 4.

4.

A Conserved Residue, Tyrosine (Y) 84, in H5N1 Influenza A Virus NS1 Regulates IFN Signaling Responses to Enhance Viral Infection.

Wang BX, Wei L, Kotra LP, Brown EG, Fish EN.

Viruses. 2017 May 12;9(5). pii: E107. doi: 10.3390/v9050107.

5.

Differential effects of NS1 proteins of human pandemic H1N1/2009, avian highly pathogenic H5N1, and low pathogenic H5N2 influenza A viruses on cellular pre-mRNA polyadenylation and mRNA translation.

Kainov DE, Müller KH, Theisen LL, Anastasina M, Kaloinen M, Muller CP.

J Biol Chem. 2011 Mar 4;286(9):7239-47. doi: 10.1074/jbc.M110.203489. Epub 2010 Dec 16.

6.

Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30.

Dankar SK, Miranda E, Forbes NE, Pelchat M, Tavassoli A, Selman M, Ping J, Jia J, Brown EG.

Virol J. 2013 Jul 25;10:243. doi: 10.1186/1743-422X-10-243.

7.

The role of nuclear NS1 protein in highly pathogenic H5N1 influenza viruses.

Mok BW, Liu H, Chen P, Liu S, Lau SY, Huang X, Liu YC, Wang P, Yuen KY, Chen H.

Microbes Infect. 2017 Dec;19(12):587-596. doi: 10.1016/j.micinf.2017.08.011. Epub 2017 Sep 10.

PMID:
28903072
8.

Synergistic effect of the PDZ and p85β-binding domains of the NS1 protein on virulence of an avian H5N1 influenza A virus.

Fan S, Macken CA, Li C, Ozawa M, Goto H, Iswahyudi NF, Nidom CA, Chen H, Neumann G, Kawaoka Y.

J Virol. 2013 May;87(9):4861-71. doi: 10.1128/JVI.02608-12. Epub 2013 Feb 13.

9.

PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.

Yu J, Li X, Wang Y, Li B, Li H, Li Y, Zhou W, Zhang C, Wang Y, Rao Z, Bartlam M, Cao Y.

PLoS One. 2011;6(5):e19511. doi: 10.1371/journal.pone.0019511. Epub 2011 May 23.

10.

SUMOylation affects the interferon blocking activity of the influenza A nonstructural protein NS1 without affecting its stability or cellular localization.

Santos A, Pal S, Chacón J, Meraz K, Gonzalez J, Prieto K, Rosas-Acosta G.

J Virol. 2013 May;87(10):5602-20. doi: 10.1128/JVI.02063-12. Epub 2013 Mar 6.

11.

A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity.

Wang J, Zeng Y, Xu S, Yang J, Wang W, Zhong B, Ge J, Yin L, Bu Z, Shu HB, Chen H, Lei CQ, Zhu Q.

J Virol. 2018 May 14;92(11). pii: e00149-18. doi: 10.1128/JVI.00149-18. Print 2018 Jun 1.

12.

Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.

Jia D, Rahbar R, Chan RW, Lee SM, Chan MC, Wang BX, Baker DP, Sun B, Peiris JS, Nicholls JM, Fish EN.

PLoS One. 2010 Nov 10;5(11):e13927. doi: 10.1371/journal.pone.0013927.

13.

Sumoylation of influenza A virus nucleoprotein is essential for intracellular trafficking and virus growth.

Han Q, Chang C, Li L, Klenk C, Cheng J, Chen Y, Xia N, Shu Y, Chen Z, Gabriel G, Sun B, Xu K.

J Virol. 2014 Aug;88(16):9379-90. doi: 10.1128/JVI.00509-14. Epub 2014 Jun 11.

14.

The distinct binding properties between avian/human influenza A virus NS1 and Postsynaptic density protein-95 (PSD-95), and inhibition of nitric oxide production.

Zhang H, Li W, Wang G, Su Y, Zhang C, Chen X, Xu Y, Li K.

Virol J. 2011 Jun 13;8:298. doi: 10.1186/1743-422X-8-298.

15.

Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens.

Trapp S, Soubieux D, Marty H, Esnault E, Hoffmann TW, Chandenier M, Lion A, Kut E, Quéré P, Larcher T, Ledevin M, Munier S, Naffakh N, Marc D.

J Gen Virol. 2014 Jun;95(Pt 6):1233-43. doi: 10.1099/vir.0.063776-0. Epub 2014 Apr 2.

PMID:
24694396
16.

Effect on virulence and pathogenicity of H5N1 influenza A virus through truncations of NS1 eIF4GI binding domain.

Zhou H, Zhu J, Tu J, Zou W, Hu Y, Yu Z, Yin W, Li Y, Zhang A, Wu Y, Yu Z, Chen H, Jin M.

J Infect Dis. 2010 Nov 1;202(9):1338-46. doi: 10.1086/656536.

PMID:
20854176
17.

Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription.

Kuo RL, Zhao C, Malur M, Krug RM.

Virology. 2010 Dec 20;408(2):146-58. doi: 10.1016/j.virol.2010.09.012. Epub 2010 Oct 8.

18.

Direct interaction of cellular hnRNP-F and NS1 of influenza A virus accelerates viral replication by modulation of viral transcriptional activity and host gene expression.

Lee JH, Kim SH, Pascua PN, Song MS, Baek YH, Jin X, Choi JK, Kim CJ, Kim H, Choi YK.

Virology. 2010 Feb 5;397(1):89-99. doi: 10.1016/j.virol.2009.10.041. Epub 2009 Nov 18. Retraction in: Virology. 2013 Feb 5;436(1):245.

19.

Influenza A virus NS1 induces G0/G1 cell cycle arrest by inhibiting the expression and activity of RhoA protein.

Jiang W, Wang Q, Chen S, Gao S, Song L, Liu P, Huang W.

J Virol. 2013 Mar;87(6):3039-52. doi: 10.1128/JVI.03176-12. Epub 2013 Jan 2.

20.

The NS1 protein of influenza A virus interacts with heat shock protein Hsp90 in human alveolar basal epithelial cells: implication for virus-induced apoptosis.

Zhang C, Yang Y, Zhou X, Yang Z, Liu X, Cao Z, Song H, He Y, Huang P.

Virol J. 2011 Apr 19;8:181. doi: 10.1186/1743-422X-8-181.

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