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Cyclin T1/CDK9 interacts with influenza A virus polymerase and facilitates its association with cellular RNA polymerase II.

Zhang J, Li G, Ye X.

J Virol. 2010 Dec;84(24):12619-27. doi: 10.1128/JVI.01696-10. Epub 2010 Oct 13.


RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II.

Martínez-Alonso M, Hengrung N, Fodor E.

J Virol. 2016 Jun 10;90(13):6014-6021. doi: 10.1128/JVI.00494-16. Print 2016 Jul 1.


Polo-like kinase 1 inhibits the activity of positive transcription elongation factor of RNA Pol II b (P-TEFb).

Jiang L, Huang Y, Deng M, Liu T, Lai W, Ye X.

PLoS One. 2013 Aug 16;8(8):e72289. doi: 10.1371/journal.pone.0072289. eCollection 2013.


The CDK9/cyclin T1 subunits of P-TEFb in mouse oocytes and preimplantation embryos: a possible role in embryonic genome activation.

Oqani RK, Kim HR, Diao YF, Park CS, Jin DI.

BMC Dev Biol. 2011 Jun 3;11:33. doi: 10.1186/1471-213X-11-33.


Recruitment of cyclin-dependent kinase 9 to nuclear compartments during cytomegalovirus late replication: importance of an interaction between viral pUL69 and cyclin T1.

Feichtinger S, Stamminger T, Müller R, Graf L, Klebl B, Eickhoff J, Marschall M.

J Gen Virol. 2011 Jul;92(Pt 7):1519-31. doi: 10.1099/vir.0.030494-0. Epub 2011 Mar 30.


Structural basis of an essential interaction between influenza polymerase and Pol II CTD.

Lukarska M, Fournier G, Pflug A, Resa-Infante P, Reich S, Naffakh N, Cusack S.

Nature. 2017 Jan 5;541(7635):117-121. doi: 10.1038/nature20594. Epub 2016 Dec 21.


EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5.

Bark-Jones SJ, Webb HM, West MJ.

Oncogene. 2006 Mar 16;25(12):1775-85.


The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression.

Hou T, Ray S, Brasier AR.

J Biol Chem. 2007 Dec 21;282(51):37091-102. Epub 2007 Oct 23.


A single point mutation in cyclin T1 eliminates binding to Hexim1, Cdk9 and RNA but not to AFF4 and enforces repression of HIV transcription.

Kuzmina A, Verstraete N, Galker S, Maatook M, Bensaude O, Taube R.

Retrovirology. 2014 Jul 1;11:51. doi: 10.1186/1742-4690-11-51.


Influenza virus inhibits RNA polymerase II elongation.

Chan AY, Vreede FT, Smith M, Engelhardt OG, Fodor E.

Virology. 2006 Jul 20;351(1):210-7. Epub 2006 Apr 19.


Functional association between viral and cellular transcription during influenza virus infection.

Engelhardt OG, Fodor E.

Rev Med Virol. 2006 Sep-Oct;16(5):329-45. Review.


Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription.

Ou M, Sandri-Goldin RM.

PLoS One. 2013 Oct 18;8(10):e79007. doi: 10.1371/journal.pone.0079007. eCollection 2013.


Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in mice.

Llompart CM, Nieto A, Rodriguez-Frandsen A.

J Virol. 2014 Mar;88(6):3455-63. doi: 10.1128/JVI.02263-13. Epub 2014 Jan 8.


G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb).

Qi T, Tang W, Wang L, Zhai L, Guo L, Zeng X.

J Biol Chem. 2011 Apr 29;286(17):15171-81. doi: 10.1074/jbc.M110.184374. Epub 2011 Mar 4.

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