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Items: 1 to 20 of 216

1.

Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication.

Poat B, Hazari S, Chandra PK, Gunduz F, Alvarez X, Balart LA, Garry RF, Dash S.

Virol J. 2010 Oct 12;7:265. doi: 10.1186/1743-422X-7-265.

2.

SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.

Poat B, Hazari S, Chandra PK, Gunduz F, Balart LA, Alvarez X, Dash S.

PLoS One. 2010 Sep 30;5(9). pii: e13117. doi: 10.1371/journal.pone.0013117.

3.

Differential regulation of Tetraodon nigroviridis Mx gene promoter activity by constitutively-active forms of STAT1, STAT2, and IRF9.

Cheng CH, Chou CM, Chu CY, Chen GD, Lien HW, Hwang PP, Chang MS, Huang CJ.

Fish Shellfish Immunol. 2014 May;38(1):230-43. doi: 10.1016/j.fsi.2014.03.017. Epub 2014 Mar 27.

PMID:
24680831
4.

Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Plumlee CR, Lazaro CA, Fausto N, Polyak SJ.

Virol J. 2005 Dec 2;2:89.

5.

IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway.

Zhang L, Jilg N, Shao RX, Lin W, Fusco DN, Zhao H, Goto K, Peng LF, Chen WC, Chung RT.

J Hepatol. 2011 Aug;55(2):289-98. doi: 10.1016/j.jhep.2010.11.019. Epub 2010 Dec 13.

6.

Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway.

Hazari S, Chandra PK, Poat B, Datta S, Garry RF, Foster TP, Kousoulas G, Wakita T, Dash S.

Virol J. 2010 Feb 11;7:36. doi: 10.1186/1743-422X-7-36.

7.

Mice deficient in STAT1 but not STAT2 or IRF9 develop a lethal CD4+ T-cell-mediated disease following infection with lymphocytic choriomeningitis virus.

Hofer MJ, Li W, Manders P, Terry R, Lim SL, King NJ, Campbell IL.

J Virol. 2012 Jun;86(12):6932-46. doi: 10.1128/JVI.07147-11. Epub 2012 Apr 11.

8.

A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response.

Kraus TA, Lau JF, Parisien JP, Horvath CM.

J Biol Chem. 2003 Apr 11;278(15):13033-8. Epub 2003 Feb 5.

9.

Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9.

Li W, Hofer MJ, Songkhunawej P, Jung SR, Hancock D, Denyer G, Campbell IL.

J Biol Chem. 2017 Apr 7;292(14):5845-5859. doi: 10.1074/jbc.M116.756510. Epub 2017 Feb 17.

10.

Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections.

Wang W, Yin Y, Xu L, Su J, Huang F, Wang Y, Boor PPC, Chen K, Wang W, Cao W, Zhou X, Liu P, van der Laan LJW, Kwekkeboom J, Peppelenbosch MP, Pan Q.

Sci Signal. 2017 Apr 25;10(476). pii: eaah4248. doi: 10.1126/scisignal.aah4248.

PMID:
28442624
11.

STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response and antiviral activity in the absence of STAT1.

Blaszczyk K, Olejnik A, Nowicka H, Ozgyin L, Chen YL, Chmielewski S, Kostyrko K, Wesoly J, Balint BL, Lee CK, Bluyssen HA.

Biochem J. 2015 Mar 15;466(3):511-24. doi: 10.1042/BJ20140644.

12.

Differential effects of calcineurin inhibitors, tacrolimus and cyclosporin a, on interferon-induced antiviral protein in human hepatocyte cells.

Hirano K, Ichikawa T, Nakao K, Matsumoto A, Miyaaki H, Shibata H, Eguchi S, Takatsuki M, Ikeda M, Yamasaki H, Kato N, Kanematsu T, Ishii N, Eguchi K.

Liver Transpl. 2008 Mar;14(3):292-8. doi: 10.1002/lt.21358.

13.

Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes.

de Lucas S, Bartolome J, Carreno V.

J Infect Dis. 2005 Jan 1;191(1):93-9. Epub 2004 Nov 29.

PMID:
15593009
14.

Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1.

Datta S, Hazari S, Chandra PK, Samara M, Poat B, Gunduz F, Wimley WC, Hauser H, Koster M, Lamaze C, Balart LA, Garry RF, Dash S.

Virol J. 2011 Jul 14;8:351. doi: 10.1186/1743-422X-8-351.

15.

The unique role of STAT2 in constitutive and IFN-induced transcription and antiviral responses.

Blaszczyk K, Nowicka H, Kostyrko K, Antonczyk A, Wesoly J, Bluyssen HA.

Cytokine Growth Factor Rev. 2016 Jun;29:71-81. doi: 10.1016/j.cytogfr.2016.02.010. Epub 2016 Mar 18. Review.

16.

IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System.

Aboulnasr F, Hazari S, Nayak S, Chandra PK, Panigrahi R, Ferraris P, Chava S, Kurt R, Song K, Dash A, Balart LA, Garry RF, Wu T, Dash S.

PLoS One. 2015 Dec 11;10(12):e0141655. doi: 10.1371/journal.pone.0141655. eCollection 2015.

17.

HCV NS5A and IRF9 compete for CypA binding.

Bobardt M, Hopkins S, Baugh J, Chatterji U, Hernandez F, Hiscott J, Sluder A, Lin K, Gallay PA.

J Hepatol. 2013 Jan;58(1):16-23. doi: 10.1016/j.jhep.2012.08.007. Epub 2012 Aug 15.

18.

Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.

Zurney J, Kobayashi T, Holm GH, Dermody TS, Sherry B.

J Virol. 2009 Mar;83(5):2178-87. doi: 10.1128/JVI.01787-08. Epub 2008 Dec 24.

19.

Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in hepatitis C virus replicon.

Hazari S, Taylor L, Haque S, Garry RF, Florman S, Luftig R, Regenstein F, Dash S.

Virol J. 2007 Sep 18;4:89.

20.

Inhibition of STAT Pathway Impairs Anti-Hepatitis C Virus Effect of Interferon Alpha.

Zhao LJ, He SF, Liu Y, Zhao P, Bian ZQ, Qi ZT.

Cell Physiol Biochem. 2016;40(1-2):77-90. Epub 2016 Nov 18.

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