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Items: 1 to 20 of 86


VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death.

Li B, Xu W, Luo C, Gozal D, Liu R.

Brain Res Mol Brain Res. 2003 Mar 17;111(1-2):155-64.


Berberine activates Nrf2 nuclear translocation and protects against oxidative damage via a phosphatidylinositol 3-kinase/Akt-dependent mechanism in NSC34 motor neuron-like cells.

Hsu YY, Chen CS, Wu SN, Jong YJ, Lo YC.

Eur J Pharm Sci. 2012 Aug 15;46(5):415-25. doi: 10.1016/j.ejps.2012.03.004. Epub 2012 Mar 24.


Ouabain stimulates protein kinase B (Akt) phosphorylation in opossum kidney proximal tubule cells through an ERK-dependent pathway.

Khundmiri SJ, Amin V, Henson J, Lewis J, Ameen M, Rane MJ, Delamere NA.

Am J Physiol Cell Physiol. 2007 Sep;293(3):C1171-80. Epub 2007 Jul 18.


Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

Horowitz JC, Lee DY, Waghray M, Keshamouni VG, Thomas PE, Zhang H, Cui Z, Thannickal VJ.

J Biol Chem. 2004 Jan 9;279(2):1359-67. Epub 2003 Oct 23.


New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.

Hales EC, Taub JW, Matherly LH.

Cell Signal. 2014 Jan;26(1):149-61. doi: 10.1016/j.cellsig.2013.09.021. Epub 2013 Oct 16. Review.


Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.

Zingg D, Riesterer O, Fabbro D, Glanzmann C, Bodis S, Pruschy M.

Cancer Res. 2004 Aug 1;64(15):5398-406.


Phosphatidylinositol 3-kinase/Akt positively regulates Fas (CD95)-mediated apoptosis in epidermal Cl41 cells.

Lu B, Wang L, Stehlik C, Medan D, Huang C, Hu S, Chen F, Shi X, Rojanasakul Y.

J Immunol. 2006 Jun 1;176(11):6785-93.


Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.

Sinha D, Wang Z, Ruchalski KL, Levine JS, Krishnan S, Lieberthal W, Schwartz JH, Borkan SC.

Am J Physiol Renal Physiol. 2005 Apr;288(4):F703-13. Epub 2004 Nov 30.


Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation.

Troussard AA, Mawji NM, Ong C, Mui A, St -Arnaud R, Dedhar S.

J Biol Chem. 2003 Jun 20;278(25):22374-8. Epub 2003 Apr 8.


The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.

Lee YI, Kang-Park S, Do SI, Lee YI.

J Biol Chem. 2001 May 18;276(20):16969-77. Epub 2001 Mar 1.


SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models.

Ono Y, Tanaka H, Takata M, Nagahara Y, Noda Y, Tsuruma K, Shimazawa M, Hozumi I, Hara H.

Neurosci Lett. 2014 Jan 24;559:174-8. doi: 10.1016/j.neulet.2013.12.005. Epub 2013 Dec 12.


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