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Items: 1 to 20 of 119

1.

Helicobacter pylori VacA reduces the cellular expression of STAT3 and pro-survival Bcl-2 family proteins, Bcl-2 and Bcl-XL, leading to apoptosis in gastric epithelial cells.

Matsumoto A, Isomoto H, Nakayama M, Hisatsune J, Nishi Y, Nakashima Y, Matsushima K, Kurazono H, Nakao K, Hirayama T, Kohno S.

Dig Dis Sci. 2011 Apr;56(4):999-1006. doi: 10.1007/s10620-010-1420-1. Epub 2010 Oct 7.

PMID:
20927590
2.

Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation.

Yamasaki E, Wada A, Kumatori A, Nakagawa I, Funao J, Nakayama M, Hisatsune J, Kimura M, Moss J, Hirayama T.

J Biol Chem. 2006 Apr 21;281(16):11250-9. Epub 2006 Jan 25.

3.

Cortactin Mediates Apoptosis of Gastric Epithelial Cells Induced by VacA Protein of Helicobacter pylori.

Chang H, Chen D, Ni B, Zuo Q, Wang C, Han R, Lan C.

Dig Dis Sci. 2016 Jan;61(1):80-90. doi: 10.1007/s10620-015-3836-0. Epub 2015 Aug 20.

PMID:
26289258
4.

Endoplasmic reticulum stress contributes to Helicobacter pylori VacA-induced apoptosis.

Akazawa Y, Isomoto H, Matsushima K, Kanda T, Minami H, Yamaghchi N, Taura N, Shiozawa K, Ohnita K, Takeshima F, Nakano M, Moss J, Hirayama T, Nakao K.

PLoS One. 2013 Dec 13;8(12):e82322. doi: 10.1371/journal.pone.0082322. eCollection 2013.

5.

Differential regulation of ERK1/2 and p38 MAP kinases in VacA-induced apoptosis of gastric epithelial cells.

Ki MR, Lee HR, Goo MJ, Hong IH, Do SH, Jeong DH, Yang HJ, Yuan DW, Park JK, Jeong KS.

Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G635-47. Epub 2007 Dec 20.

6.

The mechanism of heat-shock protein 70 gene expression abolition in gastric epithelium caused by Helicobacter pylori infection.

Pierzchalski P, Krawiec A, Ptak-Belowska A, Barańska A, Konturek SJ, Pawlik WW.

Helicobacter. 2006 Apr;11(2):96-104.

PMID:
16579839
7.

Helicobacter pylori VacA activates the p38/activating transcription factor 2-mediated signal pathway in AZ-521 cells.

Nakayama M, Kimura M, Wada A, Yahiro K, Ogushi K, Niidome T, Fujikawa A, Shirasaka D, Aoyama N, Kurazono H, Noda M, Moss J, Hirayama T.

J Biol Chem. 2004 Feb 20;279(8):7024-8. Epub 2003 Nov 20.

8.

Helicobacter pylori induces apoptosis in gastric mucosa through an upregulation of Bax expression in humans.

Konturek PC, Pierzchalski P, Konturek SJ, Meixner H, Faller G, Kirchner T, Hahn EG.

Scand J Gastroenterol. 1999 Apr;34(4):375-83.

PMID:
10365897
9.
10.

Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.

Lee KS, Kalantzis A, Jackson CB, O'Connor L, Murata-Kamiya N, Hatakeyama M, Judd LM, Giraud AS, Menheniott TR.

PLoS One. 2012;7(2):e30786. doi: 10.1371/journal.pone.0030786. Epub 2012 Feb 1.

11.

Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin.

Cover TL, Krishna US, Israel DA, Peek RM Jr.

Cancer Res. 2003 Mar 1;63(5):951-7.

12.

Helicobacter pylori vacuolating cytotoxin induces apoptosis via activation of endoplasmic reticulum stress in dendritic cells.

Kim JM, Kim JS, Kim N, Ko SH, Jeon JI, Kim YJ.

J Gastroenterol Hepatol. 2015 Jan;30(1):99-108. doi: 10.1111/jgh.12663.

PMID:
25041690
13.
14.

Vacuolating cytotoxin purified from Helicobacter pylori causes mitochondrial damage in human gastric cells.

Kimura M, Goto S, Wada A, Yahiro K, Niidome T, Hatakeyama T, Aoyagi H, Hirayama T, Kondo T.

Microb Pathog. 1999 Jan;26(1):45-52.

PMID:
9973580
15.

Helicobacter pylori VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway.

Zhu P, Xue J, Zhang ZJ, Jia YP, Tong YN, Han D, Li Q, Xiang Y, Mao XH, Tang B.

Cell Death Dis. 2017 Dec 13;8(12):3207. doi: 10.1038/s41419-017-0011-x.

16.

Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Oldani A, Cormont M, Hofman V, Chiozzi V, Oregioni O, Canonici A, Sciullo A, Sommi P, Fabbri A, Ricci V, Boquet P.

PLoS Pathog. 2009 Oct;5(10):e1000603. doi: 10.1371/journal.ppat.1000603. Epub 2009 Oct 2.

17.

Instrumental Role of Helicobacter pylori γ-Glutamyl Transpeptidase in VacA-Dependent Vacuolation in Gastric Epithelial Cells.

Ling SS, Khoo LH, Hwang LA, Yeoh KG, Ho B.

PLoS One. 2015 Jun 25;10(6):e0131460. doi: 10.1371/journal.pone.0131460. eCollection 2015.

18.

Stimulation of dendritic cells with Helicobacter pylori vacuolating cytotoxin negatively regulates their maturation via the restoration of E2F1.

Kim JM, Kim JS, Yoo DY, Ko SH, Kim N, Kim H, Kim YJ.

Clin Exp Immunol. 2011 Oct;166(1):34-45. doi: 10.1111/j.1365-2249.2011.04447.x.

19.

A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas.

Lee TL, Yeh J, Friedman J, Yan B, Yang X, Yeh NT, Van Waes C, Chen Z.

Int J Cancer. 2008 May 1;122(9):1987-98. doi: 10.1002/ijc.23324.

20.

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