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Items: 1 to 20 of 84

1.

Ethanol-mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA-lesions.

Millonig G, Wang Y, Homann N, Bernhardt F, Qin H, Mueller S, Bartsch H, Seitz HK.

Int J Cancer. 2011 Feb 1;128(3):533-40. doi: 10.1002/ijc.25604.

2.

The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts.

Linhart K, Bartsch H, Seitz HK.

Redox Biol. 2014;3:56-62. doi: 10.1016/j.redox.2014.08.009. Epub 2014 Sep 6. Review.

3.

Possible Mechanisms of Ethanol-Mediated Colorectal Carcinogenesis: The Role of Cytochrome P4502E1, Etheno-DNA Adducts, and the Anti-Apoptotic Protein Mcl-1.

Koehler BC, Arslic-Schmitt T, Peccerella T, Scherr AL, Schulze-Bergkamen H, Bruckner T, Gdynia G, Jäger D, Mueller S, Bartsch H, Seitz HK.

Alcohol Clin Exp Res. 2016 Oct;40(10):2094-2101. doi: 10.1111/acer.13180. Epub 2016 Sep 1.

PMID:
27581253
4.

Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease.

Wang Y, Millonig G, Nair J, Patsenker E, Stickel F, Mueller S, Bartsch H, Seitz HK.

Hepatology. 2009 Aug;50(2):453-61. doi: 10.1002/hep.22978.

PMID:
19489076
5.

The role of cytochrome P450 2E1 in ethanol-mediated carcinogenesis.

Seitz HK, Wang XD.

Subcell Biochem. 2013;67:131-43. doi: 10.1007/978-94-007-5881-0_3. Review.

PMID:
23400919
6.

Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesis.

Hwang PH, Lian L, Zavras AI.

Med Hypotheses. 2012 Feb;78(2):197-202. doi: 10.1016/j.mehy.2011.10.023. Epub 2011 Nov 17.

7.

Ethanol enhances the formation of endogenously and exogenously derived adducts in rat hepatic DNA.

Navasumrit P, Ward TH, O'Connor PJ, Nair J, Frank N, Bartsch H.

Mutat Res. 2001 Aug 8;479(1-2):81-94.

PMID:
11470483
8.

Carcinogenic Etheno DNA Adducts in Alcoholic Liver Disease: Correlation with Cytochrome P-4502E1 and Fibrosis.

Mueller S, Peccerella T, Qin H, Glassen K, Waldherr R, Flechtenmacher C, Straub BK, Millonig G, Stickel F, Bruckner T, Bartsch H, Seitz HK.

Alcohol Clin Exp Res. 2018 Feb;42(2):252-259. doi: 10.1111/acer.13546. Epub 2017 Dec 19.

PMID:
29120493
9.

Alcohol and cancer: an overview with special emphasis on the role of acetaldehyde and cytochrome P450 2E1.

Seitz HK, Mueller S.

Adv Exp Med Biol. 2015;815:59-70. doi: 10.1007/978-3-319-09614-8_4. Review.

PMID:
25427901
10.

Alcohol consumption and cancer of the gastrointestinal tract.

Seitz HK, Maurer B, Stickel F.

Dig Dis. 2005;23(3-4):297-303. Review.

PMID:
16508294
11.

Effect of chronic dietary ethanol in the promotion of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.

Tsutsumi M, George J, Ishizawa K, Fukumura A, Takase S.

J Gastroenterol Hepatol. 2006 May;21(5):805-13.

PMID:
16704527
12.

Role of alcohol dehydrogenase 3 and cytochrome P-4502E1 genotypes in susceptibility to cancers of the upper aerodigestive tract.

Bouchardy C, Hirvonen A, Coutelle C, Ward PJ, Dayer P, Benhamou S.

Int J Cancer. 2000 Sep 1;87(5):734-40.

13.

The generation of carcinogenic etheno-DNA adducts in the liver of patients with nonalcoholic fatty liver disease.

Linhart KB, Glassen K, Peccerella T, Waldherr R, Linhart H, Bartsch H, Seitz HK.

Hepatobiliary Surg Nutr. 2015 Apr;4(2):117-23. doi: 10.3978/j.issn.2304-3881.2015.01.14.

14.

The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus.

Tatematsu K, Koide A, Morimura K, Fukushima S, Mori Y.

Mutagenesis. 2013 Mar;28(2):161-9. doi: 10.1093/mutage/ges066. Epub 2013 Jan 15.

PMID:
23325793
15.

Early alcoholic liver injury: formation of protein adducts with acetaldehyde and lipid peroxidation products, and expression of CYP2E1 and CYP3A.

Niemelä O, Parkkila S, Pasanen M, Iimuro Y, Bradford B, Thurman RG.

Alcohol Clin Exp Res. 1998 Dec;22(9):2118-24.

PMID:
9884160
16.

Formation of acetaldehyde-derived DNA adducts due to alcohol exposure.

Yu HS, Oyama T, Isse T, Kitagawa K, Pham TT, Tanaka M, Kawamoto T.

Chem Biol Interact. 2010 Dec 5;188(3):367-75. doi: 10.1016/j.cbi.2010.08.005. Epub 2010 Sep 21. Review.

PMID:
20813101
17.

Alcohol and cancer.

Pöschl G, Seitz HK.

Alcohol Alcohol. 2004 May-Jun;39(3):155-65. Review.

PMID:
15082451
18.

Safrole-DNA adducts in tissues from esophageal cancer patients: clues to areca-related esophageal carcinogenesis.

Lee JM, Liu TY, Wu DC, Tang HC, Leh J, Wu MT, Hsu HH, Huang PM, Chen JS, Lee CJ, Lee YC.

Mutat Res. 2005 Jan 3;565(2):121-8.

PMID:
15661610
19.

Detection of carcinogenic etheno-DNA adducts in children and adolescents with non-alcoholic steatohepatitis (NASH).

Teufel U, Peccerella T, Engelmann G, Bruckner T, Flechtenmacher C, Millonig G, Stickel F, Hoffmann GF, Schirmacher P, Mueller S, Bartsch H, Seitz HK.

Hepatobiliary Surg Nutr. 2015 Dec;4(6):426-35. doi: 10.3978/j.issn.2304-3881.2015.12.03.

20.

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