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Items: 1 to 20 of 179

1.

Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation.

Tsang YH, Lamb A, Romero-Gallo J, Huang B, Ito K, Peek RM Jr, Ito Y, Chen LF.

Oncogene. 2010 Oct 14;29(41):5643-50. doi: 10.1038/onc.2010.304. Epub 2010 Aug 2.

2.

RUNX3 Methylation, Loss of RUNX3 Expression and Clinicopathologic Findings according to Helicobacter pylori CagA in Gastric Carcinoma.

Na YJ, Shim KN, Joo YH, Kim SE, Jung HK, Jung SA, Cho MS.

Korean J Gastroenterol. 2015 Aug;66(2):75-84. doi: 10.4166/kjg.2015.66.2.75.

3.

Helicobacter pylori CagA inhibits the expression of Runx3 via Src/MEK/ERK and p38 MAPK pathways in gastric epithelial cell.

Liu Z, Xu X, Chen L, Li W, Sun Y, Zeng J, Yu H, Chen C, Jia J.

J Cell Biochem. 2012 Mar;113(3):1080-6. doi: 10.1002/jcb.23440.

PMID:
22266963
4.

Evaluation of the relationship between dietary factors, CagA-positive Helicobacter pylori infection, and RUNX3 promoter hypermethylation in gastric cancer tissue.

Zhang YW, Eom SY, Yim DH, Song YJ, Yun HY, Park JS, Youn SJ, Kim BS, Kim YD, Kim H.

World J Gastroenterol. 2013 Mar 21;19(11):1778-87. doi: 10.3748/wjg.v19.i11.1778.

5.

An inverse relationship between the expression of the gastric tumor suppressor RUNX3 and infection with Helicobacter pylori in gastric epithelial dysplasia.

Chung WC, Jung SH, Joo KR, Kim MJ, Youn GJ, Kim Y, Lee JS, Lee H, Jung JH, Lee YK.

Gut Liver. 2013 Nov;7(6):688-95. doi: 10.5009/gnl.2013.7.6.688. Epub 2013 Nov 11.

6.
7.

Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway.

Li N, Feng Y, Hu Y, He C, Xie C, Ouyang Y, Artim SC, Huang D, Zhu Y, Luo Z, Ge Z, Lu N.

J Exp Clin Cancer Res. 2018 Nov 22;37(1):280. doi: 10.1186/s13046-018-0962-5.

9.

Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Oldani A, Cormont M, Hofman V, Chiozzi V, Oregioni O, Canonici A, Sciullo A, Sommi P, Fabbri A, Ricci V, Boquet P.

PLoS Pathog. 2009 Oct;5(10):e1000603. doi: 10.1371/journal.ppat.1000603. Epub 2009 Oct 2.

10.

Helicobacter pylori CagA protein induces factors involved in the epithelial to mesenchymal transition (EMT) in infected gastric epithelial cells in an EPIYA- phosphorylation-dependent manner.

Sougleri IS, Papadakos KS, Zadik MP, Mavri-Vavagianni M, Mentis AF, Sgouras DN.

FEBS J. 2016 Jan;283(2):206-20. doi: 10.1111/febs.13592. Epub 2015 Dec 11.

11.

Phosphorylation of the gastric tumor suppressor RUNX3 following H. pylori infection results in its localization to the cytoplasm.

Cinghu S, Goh YM, Oh BC, Lee YS, Lee OJ, Devaraj H, Bae SC.

J Cell Physiol. 2012 Mar;227(3):1071-80. doi: 10.1002/jcp.22820.

PMID:
21567391
12.

Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1.

Noto JM, Piazuelo MB, Chaturvedi R, Bartel CA, Thatcher EJ, Delgado A, Romero-Gallo J, Wilson KT, Correa P, Patton JG, Peek RM Jr.

Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(11):G786-96. doi: 10.1152/ajpgi.00279.2013. Epub 2013 Oct 17.

13.

H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2.

Song X, Chen HX, Wang XY, Deng XY, Xi YX, He Q, Peng TL, Chen J, Chen W, Wong BC, Chen MH.

Cell Immunol. 2013 Nov-Dec;286(1-2):22-30. doi: 10.1016/j.cellimm.2013.10.008. Epub 2013 Nov 9.

PMID:
24287273
14.

Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathways.

Yong X, Tang B, Li BS, Xie R, Hu CJ, Luo G, Qin Y, Dong H, Yang SM.

Cell Commun Signal. 2015 Jul 11;13:30. doi: 10.1186/s12964-015-0111-0. Review.

15.

Novel effects of Helicobacter pylori CagA on key genes of gastric cancer signal transduction: a comparative transfection study.

Vaziri F, Peerayeh SN, Alebouyeh M, Maghsoudi N, Azimzadeh P, Siadat SD, Zali MR.

Pathog Dis. 2015 Apr;73(3). pii: ftu021. doi: 10.1093/femspd/ftu021. Epub 2014 Dec 12.

PMID:
25743471
16.

Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells.

Yokoyama K, Higashi H, Ishikawa S, Fujii Y, Kondo S, Kato H, Azuma T, Wada A, Hirayama T, Aburatani H, Hatakeyama M.

Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9661-6. Epub 2005 Jun 24.

17.

A role for RUNX3 in inflammation-induced expression of IL23A in gastric epithelial cells.

Hor YT, Voon DC, Koo JK, Wang H, Lau WM, Ashktorab H, Chan SL, Ito Y.

Cell Rep. 2014 Jul 10;8(1):50-8. doi: 10.1016/j.celrep.2014.06.003. Epub 2014 Jul 5.

18.

Stability of Helicobacter pylori CagA oncoprotein in human gastric epithelial cells.

Ishikawa S, Ohta T, Hatakeyama M.

FEBS Lett. 2009 Jul 21;583(14):2414-8. doi: 10.1016/j.febslet.2009.06.043. Epub 2009 Jun 26.

19.
20.

The effect of Helicobacter pylori CagA on the HER-2 copy number and expression in gastric cancer.

Shim JH, Yoon JH, Choi SS, Ashktorab H, Smoot DT, Song KY, Nam SW, Lee JY, Park CH, Park WS.

Gene. 2014 Aug 10;546(2):288-96. doi: 10.1016/j.gene.2014.05.064. Epub 2014 May 28.

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