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Items: 1 to 20 of 214

1.

Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis.

Osborn SL, Diehl G, Han SJ, Xue L, Kurd N, Hsieh K, Cado D, Robey EA, Winoto A.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13034-9. doi: 10.1073/pnas.1005997107. Epub 2010 Jul 6.

2.

Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity.

Lu JV, Weist BM, van Raam BJ, Marro BS, Nguyen LV, Srinivas P, Bell BD, Luhrs KA, Lane TE, Salvesen GS, Walsh CM.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15312-7. doi: 10.1073/pnas.1102779108. Epub 2011 Aug 29.

3.

The roles of FADD in extrinsic apoptosis and necroptosis.

Lee EW, Seo J, Jeong M, Lee S, Song J.

BMB Rep. 2012 Sep;45(9):496-508. Review.

4.

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells.

Bell BD, Leverrier S, Weist BM, Newton RH, Arechiga AF, Luhrs KA, Morrissette NS, Walsh CM.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16677-82. doi: 10.1073/pnas.0808597105. Epub 2008 Oct 22.

5.

Necroptosis in health and diseases.

Zhou W, Yuan J.

Semin Cell Dev Biol. 2014 Nov;35:14-23. doi: 10.1016/j.semcdb.2014.07.013. Epub 2014 Aug 1. Review.

6.

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.

Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, Eftychi C, Lin J, Corona T, Hermance N, Zelic M, Kirsch P, Basic M, Bleich A, Kelliher M, Pasparakis M.

Nature. 2014 Sep 4;513(7516):90-4. doi: 10.1038/nature13608. Epub 2014 Aug 17.

7.

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernández-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G, Pasparakis M.

Nature. 2011 Jul 31;477(7364):330-4. doi: 10.1038/nature10273.

PMID:
21804564
8.

Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases.

Thapa RJ, Nogusa S, Chen P, Maki JL, Lerro A, Andrake M, Rall GF, Degterev A, Balachandran S.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3109-18. doi: 10.1073/pnas.1301218110. Epub 2013 Jul 29.

9.

A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes.

He MX, He YW.

Cell Death Differ. 2013 Feb;20(2):188-97. doi: 10.1038/cdd.2012.148. Epub 2012 Nov 23.

10.

TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8.

Ikner A, Ashkenazi A.

J Biol Chem. 2011 Jun 17;286(24):21546-54. doi: 10.1074/jbc.M110.203745. Epub 2011 Apr 27.

11.

RIP3 mediates the embryonic lethality of caspase-8-deficient mice.

Kaiser WJ, Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer LP, Hakem R, Caspary T, Mocarski ES.

Nature. 2011 Mar 17;471(7338):368-72. doi: 10.1038/nature09857. Epub 2011 Mar 2.

12.

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor ╬▒-induced necroptosis.

Laukens B, Jennewein C, Schenk B, Vanlangenakker N, Schier A, Cristofanon S, Zobel K, Deshayes K, Vucic D, Jeremias I, Bertrand MJ, Vandenabeele P, Fulda S.

Neoplasia. 2011 Oct;13(10):971-9.

13.

Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway.

Schock SN, Chandra NV, Sun Y, Irie T, Kitagawa Y, Gotoh B, Coscoy L, Winoto A.

Cell Death Differ. 2017 Apr;24(4):615-625. doi: 10.1038/cdd.2016.153. Epub 2017 Jan 6.

14.

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition.

Kaiser WJ, Daley-Bauer LP, Thapa RJ, Mandal P, Berger SB, Huang C, Sundararajan A, Guo H, Roback L, Speck SH, Bertin J, Gough PJ, Balachandran S, Mocarski ES.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7753-8. doi: 10.1073/pnas.1401857111. Epub 2014 May 12.

15.

Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis.

Irrinki KM, Mallilankaraman K, Thapa RJ, Chandramoorthy HC, Smith FJ, Jog NR, Gandhirajan RK, Kelsen SG, Houser SR, May MJ, Balachandran S, Madesh M.

Mol Cell Biol. 2011 Sep;31(18):3745-58. doi: 10.1128/MCB.05303-11. Epub 2011 Jul 11.

16.

RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice.

Liu Y, Fan C, Zhang Y, Yu X, Wu X, Zhang X, Zhao Q, Zhang H, Xie Q, Li M, Li X, Ding Q, Ying H, Li D, Zhang H.

Cell Death Differ. 2017 Aug;24(8):1459-1469. doi: 10.1038/cdd.2017.78. Epub 2017 Jun 2.

17.

Coordinate regulation of autophagy and apoptosis in T cells by death effectors: FADD or foundation.

Bell BD, Walsh CM.

Autophagy. 2009 Feb;5(2):238-40. Epub 2009 Feb 1.

PMID:
19077534
18.

Functional complementation between FADD and RIP1 in embryos and lymphocytes.

Zhang H, Zhou X, McQuade T, Li J, Chan FK, Zhang J.

Nature. 2011 Mar 17;471(7338):373-6. doi: 10.1038/nature09878. Epub 2011 Mar 2. Erratum in: Nature. 2012 Mar 22;483(7390):498.

20.

Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes.

Basit F, Cristofanon S, Fulda S.

Cell Death Differ. 2013 Sep;20(9):1161-73. doi: 10.1038/cdd.2013.45. Epub 2013 Jun 7. Erratum in: Cell Death Differ. 2014 Jul;21(7):1183-4.

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