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Items: 1 to 20 of 134

1.

Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein.

Murata-Kamiya N, Kikuchi K, Hayashi T, Higashi H, Hatakeyama M.

Cell Host Microbe. 2010 May 20;7(5):399-411. doi: 10.1016/j.chom.2010.04.005.

2.

Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.

Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, Saito Y, Lu H, Ohnishi N, Azuma T, Suzuki A, Ohno S, Hatakeyama M.

Nature. 2007 May 17;447(7142):330-3.

PMID:
17507984
3.

Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA.

Hatakeyama M.

Oncogene. 2008 Nov 24;27(55):7047-54. doi: 10.1038/onc.2008.353. Review.

PMID:
19029944
4.

SagA of CagA in Helicobacter pylori pathogenesis.

Hatakeyama M.

Curr Opin Microbiol. 2008 Feb;11(1):30-7. doi: 10.1016/j.mib.2007.12.003. Epub 2008 Feb 20. Review.

PMID:
18243773
5.

Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation.

Pillinger MH, Marjanovic N, Kim SY, Lee YC, Scher JU, Roper J, Abeles AM, Izmirly PI, Axelrod M, Pillinger MY, Tolani S, Dinsell V, Abramson SB, Blaser MJ.

J Biol Chem. 2007 Jun 29;282(26):18722-31. Epub 2007 May 2.

6.

Structural and functional diversity in the PAR1b/MARK2-binding region of Helicobacter pylori CagA.

Lu HS, Saito Y, Umeda M, Murata-Kamiya N, Zhang HM, Higashi H, Hatakeyama M.

Cancer Sci. 2008 Oct;99(10):2004-11. doi: 10.1111/j.1349-7006.2008.00950.x.

7.
8.

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse.

Ohnishi N, Yuasa H, Tanaka S, Sawa H, Miura M, Matsui A, Higashi H, Musashi M, Iwabuchi K, Suzuki M, Yamada G, Azuma T, Hatakeyama M.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):1003-8. doi: 10.1073/pnas.0711183105. Epub 2008 Jan 11.

9.

[H. pylori oncoprotein CagA and gastric cancer].

Hatakeyama M.

Nihon Rinsho. 2012 Oct;70(10):1699-704. Japanese.

PMID:
23198548
10.

[Oncogenic mechanism of Helicobacter pylori].

Hatakeyama M.

Nihon Rinsho Meneki Gakkai Kaishi. 2008 Jun;31(3):132-40. Japanese.

11.

Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion.

Suzuki M, Mimuro H, Suzuki T, Park M, Yamamoto T, Sasakawa C.

J Exp Med. 2005 Nov 7;202(9):1235-47.

12.

Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERK pathways.

Zhao D, Liu Z, Ding J, Li W, Sun Y, Yu H, Zhou Y, Zeng J, Chen C, Jia J.

J Med Microbiol. 2010 Mar;59(Pt 3):259-65. doi: 10.1099/jmm.0.014704-0. Epub 2009 Dec 3.

PMID:
19959630
13.

Stability of Helicobacter pylori CagA oncoprotein in human gastric epithelial cells.

Ishikawa S, Ohta T, Hatakeyama M.

FEBS Lett. 2009 Jul 21;583(14):2414-8. doi: 10.1016/j.febslet.2009.06.043. Epub 2009 Jun 26.

14.
15.

Role of type IV secretion in Helicobacter pylori pathogenesis.

Backert S, Selbach M.

Cell Microbiol. 2008 Aug;10(8):1573-81. doi: 10.1111/j.1462-5822.2008.01156.x. Epub 2008 Apr 8. Review.

PMID:
18410539
16.

Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility.

Poppe M, Feller SM, Römer G, Wessler S.

Oncogene. 2007 May 24;26(24):3462-72. Epub 2006 Dec 11.

PMID:
17160020
17.

Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus.

Backert S, Ziska E, Brinkmann V, Zimny-Arndt U, Fauconnier A, Jungblut PR, Naumann M, Meyer TF.

Cell Microbiol. 2000 Apr;2(2):155-64.

PMID:
11207572
18.

Helicobacter pylori chaperone-like protein CagT plays an essential role in the translocation of CagA into host cells.

Ding H, Zeng H, Huang L, Dong Y, Duan Y, Mao X, Guo G, Zou Q.

J Microbiol Biotechnol. 2012 Oct;22(10):1343-9.

19.

Phosphorylation-independent effects of CagA during interaction between Helicobacter pylori and T84 polarized monolayers.

El-Etr SH, Mueller A, Tompkins LS, Falkow S, Merrell DS.

J Infect Dis. 2004 Oct 15;190(8):1516-23. Epub 2004 Sep 9.

20.

Helicobacter pylori stimulates epithelial cell migration via CagA-mediated perturbation of host cell signaling.

Kikuchi K, Murata-Kamiya N, Kondo S, Hatakeyama M.

Microbes Infect. 2012 May;14(5):470-6. doi: 10.1016/j.micinf.2011.12.003. Epub 2011 Dec 11.

PMID:
22202178

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