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Items: 1 to 20 of 148

1.

Suppressor of cytokine signaling 3 suppresses hepatitis C virus replication in an mTOR-dependent manner.

Shao RX, Zhang L, Peng LF, Sun E, Chung WJ, Jang JY, Tsai WL, Hyppolite G, Chung RT.

J Virol. 2010 Jun;84(12):6060-9. doi: 10.1128/JVI.02484-09. Epub 2010 Apr 7.

2.

Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus-related chronic hepatitis: Insulin resistance and response to antiviral therapy.

Persico M, Capasso M, Persico E, Svelto M, Russo R, Spano D, Crocè L, La Mura V, Moschella F, Masutti F, Torella R, Tiribelli C, Iolascon A.

Hepatology. 2007 Oct;46(4):1009-15.

PMID:
17668875
3.

Interferon alpha antagonizes STAT3 and SOCS3 signaling triggered by hepatitis C virus.

Zhao LJ, He SF, Wang W, Ren H, Qi ZT.

Cytokine. 2016 Apr;80:48-55. doi: 10.1016/j.cyto.2015.08.264. Epub 2016 Mar 3.

PMID:
26945996
4.

Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity.

Muraoka T, Ichikawa T, Taura N, Miyaaki H, Takeshita S, Akiyama M, Miuma S, Ozawa E, Isomoto H, Takeshima F, Nakao K.

Mol Med Rep. 2012 Feb;5(2):331-5. doi: 10.3892/mmr.2011.662. Epub 2011 Nov 3.

PMID:
22052332
5.

SOCS1 abrogates IFN's antiviral effect on hepatitis C virus replication.

Shao RX, Zhang L, Hong Z, Goto K, Cheng D, Chen WC, Jilg N, Kumthip K, Fusco DN, Peng LF, Chung RT.

Antiviral Res. 2013 Feb;97(2):101-7. doi: 10.1016/j.antiviral.2012.12.001. Epub 2012 Dec 10.

6.

SOCS3 and IRS-1 gene expression differs between genotype 1 and genotype 2 hepatitis C virus-infected HepG2 cells.

Persico M, Russo R, Persico E, Svelto M, Spano D, Andolfo I, La Mura V, Capasso M, Tiribelli C, Torella R, Iolascon A.

Clin Chem Lab Med. 2009;47(10):1217-25. doi: 10.1515/CCLM.2009.280.

PMID:
19803812
7.

The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-β signaling.

Goto K, Lin W, Zhang L, Jilg N, Shao RX, Schaefer EA, Zhao H, Fusco DN, Peng LF, Kato N, Chung RT.

J Hepatol. 2013 Nov;59(5):942-8. doi: 10.1016/j.jhep.2013.06.025. Epub 2013 Jul 2.

8.
9.

Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C.

Huang Y, Feld JJ, Sapp RK, Nanda S, Lin JH, Blatt LM, Fried MW, Murthy K, Liang TJ.

Gastroenterology. 2007 Feb;132(2):733-44. Epub 2006 Nov 29.

10.

Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy.

Huang H, Kang R, Wang J, Luo G, Yang W, Zhao Z.

Autophagy. 2013 Feb 1;9(2):175-95. doi: 10.4161/auto.22791. Epub 2012 Nov 20.

11.

Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies.

Larrea E, Aldabe R, Molano E, Fernandez-Rodriguez CM, Ametzazurra A, Civeira MP, Prieto J.

Gut. 2006 Aug;55(8):1188-96. Epub 2005 Aug 24.

12.

Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.

Kawaguchi T, Yoshida T, Harada M, Hisamoto T, Nagao Y, Ide T, Taniguchi E, Kumemura H, Hanada S, Maeyama M, Baba S, Koga H, Kumashiro R, Ueno T, Ogata H, Yoshimura A, Sata M.

Am J Pathol. 2004 Nov;165(5):1499-508.

13.

A functional genomic screen reveals novel host genes that mediate interferon-alpha's effects against hepatitis C virus.

Zhao H, Lin W, Kumthip K, Cheng D, Fusco DN, Hofmann O, Jilg N, Tai AW, Goto K, Zhang L, Hide W, Jang JY, Peng LF, Chung RT.

J Hepatol. 2012 Feb;56(2):326-33. doi: 10.1016/j.jhep.2011.07.026. Epub 2011 Aug 31.

14.

Hepatic SOCS3 expression is strongly associated with non-response to therapy and race in HCV and HCV/HIV infection.

Kim KA, Lin W, Tai AW, Shao RX, Weinberg E, De Sa Borges CB, Bhan AK, Zheng H, Kamegaya Y, Chung RT.

J Hepatol. 2009 Apr;50(4):705-11. doi: 10.1016/j.jhep.2008.12.021. Epub 2009 Feb 14.

15.

Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 91.

Funaoka Y, Sakamoto N, Suda G, Itsui Y, Nakagawa M, Kakinuma S, Watanabe T, Mishima K, Ueyama M, Onozuka I, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Watanabe M.

J Virol. 2011 Jun;85(12):5986-94. doi: 10.1128/JVI.02583-10. Epub 2011 Apr 13.

18.

MiR-221 accentuates IFN׳s anti-HCV effect by downregulating SOCS1 and SOCS3.

Xu G, Yang F, Ding CL, Wang J, Zhao P, Wang W, Ren H.

Virology. 2014 Aug;462-463:343-50. doi: 10.1016/j.virol.2014.06.024. Epub 2014 Jul 12.

19.

Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Plumlee CR, Lazaro CA, Fausto N, Polyak SJ.

Virol J. 2005 Dec 2;2:89.

20.

SOCS3 Drives Proteasomal Degradation of TBK1 and Negatively Regulates Antiviral Innate Immunity.

Liu D, Sheng C, Gao S, Yao C, Li J, Jiang W, Chen H, Wu J, Pan C, Chen S, Huang W.

Mol Cell Biol. 2015 Jul;35(14):2400-13. doi: 10.1128/MCB.00090-15. Epub 2015 May 4.

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