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Items: 1 to 20 of 103

1.

Thiazole, oxadiazole, and carboxamide derivatives of artemisinin are highly selective and potent inhibitors of Toxoplasma gondii.

Hencken CP, Jones-Brando L, Bordón C, Stohler R, Mott BT, Yolken R, Posner GH, Woodard LE.

J Med Chem. 2010 May 13;53(9):3594-601. doi: 10.1021/jm901857d.

2.

A thiazole derivative of artemisinin moderately reduces Toxoplasma gondii cyst burden in infected mice.

Schultz TL, Hencken CP, Woodard LE, Posner GH, Yolken RH, Jones-Brando L, Carruthers VB.

J Parasitol. 2014 Aug;100(4):516-21. doi: 10.1645/13-451.1. Epub 2014 Feb 13.

PMID:
24524228
3.

Artemisinin derivatives inhibit Toxoplasma gondii in vitro at multiple steps in the lytic cycle.

D'Angelo JG, Bordón C, Posner GH, Yolken R, Jones-Brando L.

J Antimicrob Chemother. 2009 Jan;63(1):146-50. doi: 10.1093/jac/dkn451. Epub 2008 Nov 6.

4.

Quinonic derivatives active against Toxoplasma gondii.

Sarciron ME, Nebois P, Pautet F, Pétavy AF, Fillion H, Walchshofer N.

Parasitol Res. 2002 Nov;88(11):969-71. Epub 2002 Jul 9.

PMID:
12375161
5.

Anti-parasitic action and elimination of intracellular Toxoplasma gondii in the presence of novel thiosemicarbazone and its 4-thiazolidinone derivatives.

Carvalho CS, Melo EJ, Tenório RP, Góes AJ.

Braz J Med Biol Res. 2010 Feb;43(2):139-49. Epub 2009 Nov 6. Erratum in: Braz J Med Biol Res. 2010 Feb;43(2):225.

6.

Design, synthesis and biological characterization of thiazolidin-4-one derivatives as promising inhibitors of Toxoplasma gondii.

D'Ascenzio M, Bizzarri B, De Monte C, Carradori S, Bolasco A, Secci D, Rivanera D, Faulhaber N, Bordón C, Jones-Brando L.

Eur J Med Chem. 2014 Oct 30;86:17-30. doi: 10.1016/j.ejmech.2014.08.046. Epub 2014 Aug 15.

PMID:
25140751
7.

Synthesis of thiosemicarbazone and 4-thiazolidinone derivatives and their in vitro anti-Toxoplasma gondii activity.

Tenório RP, Carvalho CS, Pessanha CS, de Lima JG, de Faria AR, Alves AJ, de Melo EJ, Góes AJ.

Bioorg Med Chem Lett. 2005 May 16;15(10):2575-8.

PMID:
15863319
8.

Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis.

Nagamune K, Moreno SN, Sibley LD.

Antimicrob Agents Chemother. 2007 Nov;51(11):3816-23. Epub 2007 Aug 13.

9.

In vitro inhibition of Toxoplasma gondii by four new derivatives of artemisinin.

Jones-Brando L, D'Angelo J, Posner GH, Yolken R.

Antimicrob Agents Chemother. 2006 Dec;50(12):4206-8. Epub 2006 Oct 23.

10.

Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents.

Recher M, Barboza AP, Li ZH, Galizzi M, Ferrer-Casal M, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB.

Eur J Med Chem. 2013 Feb;60:431-40. doi: 10.1016/j.ejmech.2012.12.015. Epub 2012 Dec 20.

11.

Selection and characterization of Toxoplasma gondii mutants resistant to artemisinin.

Berens RL, Krug EC, Nash PB, Curiel TJ.

J Infect Dis. 1998 Apr;177(4):1128-31.

PMID:
9534999
12.

A novel benzodioxole-containing inhibitor of Toxoplasma gondii growth alters the parasite cell cycle.

Kamau E, Meehan T, Lavine MD, Arrizabalaga G, Mustata Wilson G, Boyle J.

Antimicrob Agents Chemother. 2011 Dec;55(12):5438-51. doi: 10.1128/AAC.00455-11. Epub 2011 Sep 26.

13.

In vitro inhibition of Toxoplasma gondii by the anti-malarial candidate, 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.

Xin CF, Kim HS, Sato A, Lee HJ, Lee YW, Pyo KH, Shin EH.

Parasitol Int. 2016 Oct;65(5 Pt A):494-9. doi: 10.1016/j.parint.2016.06.013. Epub 2016 Jul 2.

PMID:
27380994
14.

1,4-Disubstituted thiosemicarbazide derivatives are potent inhibitors of Toxoplasma gondii proliferation.

Dzitko K, Paneth A, Plech T, Pawełczyk J, Stączek P, Stefańska J, Paneth P.

Molecules. 2014 Jul 9;19(7):9926-43. doi: 10.3390/molecules19079926.

15.

Synthesis and biological evaluation of anti-Toxoplasma gondii activity of a novel scaffold of thiazolidinone derivatives.

Carradori S, Secci D, Bizzarri B, Chimenti P, De Monte C, Guglielmi P, Campestre C, Rivanera D, Bordón C, Jones-Brando L.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):746-758. doi: 10.1080/14756366.2017.1316494.

16.

Inhibition of Toxoplasma gondii by indirubin and tryptanthrin analogs.

Krivogorsky B, Grundt P, Yolken R, Jones-Brando L.

Antimicrob Agents Chemother. 2008 Dec;52(12):4466-9. doi: 10.1128/AAC.00903-08. Epub 2008 Sep 29.

17.
18.

Inhibition of growth of Toxoplasma gondii by qinghaosu and derivatives.

Ke OY, Krug EC, Marr JJ, Berens RL.

Antimicrob Agents Chemother. 1990 Oct;34(10):1961-5.

19.

Gefitinib inhibits the growth of Toxoplasma gondii in HeLa cells.

Yang Z, Ahn HJ, Nam HW.

Korean J Parasitol. 2014 Aug;52(4):439-41. doi: 10.3347/kjp.2014.52.4.439. Epub 2014 Aug 29.

20.

Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs.

Esposito M, Moores S, Naguleswaran A, Müller J, Hemphill A.

Int J Parasitol. 2007 Aug;37(10):1143-52. Epub 2007 Mar 30.

PMID:
17481636

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