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Items: 1 to 20 of 114

1.

Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.

Okumura Y, Takahashi E, Yano M, Ohuchi M, Daidoji T, Nakaya T, Böttcher E, Garten W, Klenk HD, Kido H.

J Virol. 2010 May;84(10):5089-96. doi: 10.1128/JVI.02605-09. Epub 2010 Mar 10.

2.

Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.

Kido H, Okumura Y, Takahashi E, Pan HY, Wang S, Chida J, Le TQ, Yano M.

J Mol Genet Med. 2008 Nov 29;3(1):167-75.

3.
4.

Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics.

Garten W, Braden C, Arendt A, Peitsch C, Baron J, Lu Y, Pawletko K, Hardes K, Steinmetzer T, Böttcher-Friebertshäuser E.

Eur J Cell Biol. 2015 Jul-Sep;94(7-9):375-83. doi: 10.1016/j.ejcb.2015.05.013. Epub 2015 Jun 1.

PMID:
26095298
5.

Novel insights into proteolytic cleavage of influenza virus hemagglutinin.

Bertram S, Glowacka I, Steffen I, Kühl A, Pöhlmann S.

Rev Med Virol. 2010 Sep;20(5):298-310. doi: 10.1002/rmv.657. Review.

PMID:
20629046
6.

MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.

Böttcher E, Freuer C, Steinmetzer T, Klenk HD, Garten W.

Vaccine. 2009 Oct 23;27(45):6324-9. doi: 10.1016/j.vaccine.2009.03.029.

PMID:
19840668
9.

Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential.

Senne DA, Panigrahy B, Kawaoka Y, Pearson JE, Süss J, Lipkind M, Kida H, Webster RG.

Avian Dis. 1996 Apr-Jun;40(2):425-37.

PMID:
8790895
10.

Location and character of the cellular enzyme that cleaves the hemagglutinin of a virulent avian influenza virus.

Walker JA, Sakaguchi T, Matsuda Y, Yoshida T, Kawaoka Y.

Virology. 1992 Sep;190(1):278-87.

PMID:
1529533
11.

Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors.

Böttcher-Friebertshäuser E, Freuer C, Sielaff F, Schmidt S, Eickmann M, Uhlendorff J, Steinmetzer T, Klenk HD, Garten W.

J Virol. 2010 Jun;84(11):5605-14. doi: 10.1128/JVI.00140-10. Epub 2010 Mar 17.

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15.

Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R.

Vey M, Orlich M, Adler S, Klenk HD, Rott R, Garten W.

Virology. 1992 May;188(1):408-13.

PMID:
1566583
16.

DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.

Zmora P, Blazejewska P, Moldenhauer AS, Welsch K, Nehlmeier I, Wu Q, Schneider H, Pöhlmann S, Bertram S.

J Virol. 2014 Oct;88(20):12087-97. doi: 10.1128/JVI.01427-14. Epub 2014 Aug 13.

17.

Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.

Böttcher E, Matrosovich T, Beyerle M, Klenk HD, Garten W, Matrosovich M.

J Virol. 2006 Oct;80(19):9896-8.

18.

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

Stieneke-Gröber A, Vey M, Angliker H, Shaw E, Thomas G, Roberts C, Klenk HD, Garten W.

EMBO J. 1992 Jul;11(7):2407-14.

19.
20.

Influenza viruses, cell enzymes, and pathogenicity.

Rott R, Klenk HD, Nagai Y, Tashiro M.

Am J Respir Crit Care Med. 1995 Oct;152(4 Pt 2):S16-9. Review.

PMID:
7551406

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