Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 105

1.

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole.

Khaminets A, Hunn JP, Könen-Waisman S, Zhao YO, Preukschat D, Coers J, Boyle JP, Ong YC, Boothroyd JC, Reichmann G, Howard JC.

Cell Microbiol. 2010 Jul;12(7):939-61. doi: 10.1111/j.1462-5822.2010.01443.x. Epub 2010 Jan 26.

2.

The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

Niedelman W, Gold DA, Rosowski EE, Sprokholt JK, Lim D, Farid Arenas A, Melo MB, Spooner E, Yaffe MB, Saeij JP.

PLoS Pathog. 2012;8(6):e1002784. doi: 10.1371/journal.ppat.1002784. Epub 2012 Jun 28.

3.

Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.

Steinfeldt T, Könen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, Sibley LD, Hunn JP, Howard JC.

PLoS Biol. 2010 Dec 21;8(12):e1000576. doi: 10.1371/journal.pbio.1000576. Erratum in: PLoS Biol. 2015 Jul;13(7):e1002199.

4.

The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.

Hermanns T, Müller UB, Könen-Waisman S, Howard JC, Steinfeldt T.

Cell Microbiol. 2016 Feb;18(2):244-59. doi: 10.1111/cmi.12499. Epub 2015 Oct 30.

5.

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.

Zhao YO, Khaminets A, Hunn JP, Howard JC.

PLoS Pathog. 2009 Feb;5(2):e1000288. doi: 10.1371/journal.ppat.1000288. Epub 2009 Feb 6.

6.

Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review.

Zhao YO, Rohde C, Lilue JT, Könen-Waisman S, Khaminets A, Hunn JP, Howard JC.

Mem Inst Oswaldo Cruz. 2009 Mar;104(2):234-40. Review.

7.

The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii.

Fentress SJ, Steinfeldt T, Howard JC, Sibley LD.

Cell Microbiol. 2012 Dec;14(12):1921-33. doi: 10.1111/cmi.12022. Epub 2012 Sep 20.

8.

The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading.

Kim EW, Nadipuram SM, Tetlow AL, Barshop WD, Liu PT, Wohlschlegel JA, Bradley PJ.

mSphere. 2016 Mar 23;1(2). pii: e00045-16. doi: 10.1128/mSphere.00045-16. eCollection 2016 Mar-Apr.

9.

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.

Hunn JP, Koenen-Waisman S, Papic N, Schroeder N, Pawlowski N, Lange R, Kaiser F, Zerrahn J, Martens S, Howard JC.

EMBO J. 2008 Oct 8;27(19):2495-509. doi: 10.1038/emboj.2008.176. Epub 2008 Sep 4.

10.

In astrocytes the accumulation of the immunity-related GTPases Irga6 and Irgb6 at the vacuole of Toxoplasma gondii is dependent on the parasite virulence.

Lubitz FP, Degrandi D, Pfeffer K, Mausberg AK.

ScientificWorldJournal. 2013 Nov 12;2013:480231. doi: 10.1155/2013/480231. eCollection 2013.

11.

The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.

Haldar AK, Piro AS, Pilla DM, Yamamoto M, Coers J.

PLoS One. 2014 Jan 17;9(1):e86684. doi: 10.1371/journal.pone.0086684. eCollection 2014.

12.

Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages.

Zhao Y, Ferguson DJ, Wilson DC, Howard JC, Sibley LD, Yap GS.

J Immunol. 2009 Mar 15;182(6):3775-81. doi: 10.4049/jimmunol.0804190.

13.

The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens.

Hunn JP, Feng CG, Sher A, Howard JC.

Mamm Genome. 2011 Feb;22(1-2):43-54. doi: 10.1007/s00335-010-9293-3. Epub 2010 Oct 30. Review.

14.

IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.

Haldar AK, Saka HA, Piro AS, Dunn JD, Henry SC, Taylor GA, Frickel EM, Valdivia RH, Coers J.

PLoS Pathog. 2013;9(6):e1003414. doi: 10.1371/journal.ppat.1003414. Epub 2013 Jun 13.

15.

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii.

Pawlowski N, Khaminets A, Hunn JP, Papic N, Schmidt A, Uthaiah RC, Lange R, Vopper G, Martens S, Wolf E, Howard JC.

BMC Biol. 2011 Jan 28;9:7. doi: 10.1186/1741-7007-9-7.

16.

Enzymatically active Rho and Rac small-GTPases are involved in the establishment of the vacuolar membrane after Toxoplasma gondii invasion of host cells.

Na RH, Zhu GH, Luo JX, Meng XJ, Cui L, Peng HJ, Chen XG, Gomez-Cambronero J.

BMC Microbiol. 2013 May 30;13:125. doi: 10.1186/1471-2180-13-125.

17.

Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity.

Fox BA, Sanders KL, Rommereim LM, Guevara RB, Bzik DJ.

PLoS Genet. 2016 Jul 22;12(7):e1006189. doi: 10.1371/journal.pgen.1006189. eCollection 2016 Jul.

18.

Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.

Ohshima J, Lee Y, Sasai M, Saitoh T, Su Ma J, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M.

J Immunol. 2014 Apr 1;192(7):3328-35. doi: 10.4049/jimmunol.1302822. Epub 2014 Feb 21.

19.

A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins.

Fleckenstein MC, Reese ML, Könen-Waisman S, Boothroyd JC, Howard JC, Steinfeldt T.

PLoS Biol. 2012;10(7):e1001358. doi: 10.1371/journal.pbio.1001358. Epub 2012 Jul 10.

20.

The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii.

Howard JC, Hunn JP, Steinfeldt T.

Curr Opin Microbiol. 2011 Aug;14(4):414-21. doi: 10.1016/j.mib.2011.07.002. Epub 2011 Jul 23. Review.

PMID:
21783405

Supplemental Content

Support Center