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Items: 1 to 20 of 105


T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii.

Shaw MH, Reimer T, Sánchez-Valdepeñas C, Warner N, Kim YG, Fresno M, Nuñez G.

Nat Immunol. 2009 Dec;10(12):1267-74. doi: 10.1038/ni.1816. Epub 2009 Nov 1.


Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii.

Caetano BC, Biswas A, Lima DS Jr, Benevides L, Mineo TW, Horta CV, Lee KH, Silva JS, Gazzinelli RT, Zamboni DS, Kobayashi KS.

Eur J Immunol. 2011 Dec;41(12):3627-31. doi: 10.1002/eji.201141876. Epub 2011 Nov 10.


Nucleotide-oligomerization-domain-2 affects commensal gut microbiota composition and intracerebral immunopathology in acute Toxoplasma gondii induced murine ileitis.

Heimesaat MM, Dunay IR, Alutis M, Fischer A, Möhle L, Göbel UB, Kühl AA, Bereswill S.

PLoS One. 2014 Aug 20;9(8):e105120. doi: 10.1371/journal.pone.0105120. eCollection 2014.


Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii.

Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, Jankovic D, Tsichlis PN, O'Shea JJ.

J Exp Med. 2008 Nov 24;205(12):2803-12. doi: 10.1084/jem.20081461. Epub 2008 Nov 10.


T cells need Nod too?

Salek-Ardakani S, Croft M.

Nat Immunol. 2009 Dec;10(12):1231-3. doi: 10.1038/ni1209-1231. No abstract available.


The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii.

Caamaño J, Alexander J, Craig L, Bravo R, Hunter CA.

J Immunol. 1999 Oct 15;163(8):4453-61.


Nucleotide-binding oligomerization domain 2 signaling promotes hyperresponsive macrophages and colitis in IL-10-deficient mice.

Jamontt J, Petit S, Clark N, Parkinson SJ, Smith P.

J Immunol. 2013 Mar 15;190(6):2948-58. doi: 10.4049/jimmunol.1201332. Epub 2013 Feb 8.


RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4581-90. doi: 10.1073/pnas.1510031112. Epub 2015 Aug 3.


IL-21 is required for optimal antibody production and T cell responses during chronic Toxoplasma gondii infection.

Stumhofer JS, Silver JS, Hunter CA.

PLoS One. 2013 May 7;8(5):e62889. doi: 10.1371/journal.pone.0062889. Print 2013.


T cell expression of MyD88 is required for resistance to Toxoplasma gondii.

LaRosa DF, Stumhofer JS, Gelman AE, Rahman AH, Taylor DK, Hunter CA, Turka LA.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3855-60. doi: 10.1073/pnas.0706663105. Epub 2008 Feb 28.


Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii.

Bhadra R, Guan H, Khan IA.

PLoS One. 2010 May 26;5(5):e10842. doi: 10.1371/journal.pone.0010842.


Natural killer cell intrinsic toll-like receptor MyD88 signaling contributes to IL-12-dependent IFN-γ production by mice during infection with Toxoplasma gondii.

Ge Y, Chen J, Qiu X, Zhang J, Cui L, Qi Y, Liu X, Qiu J, Shi Z, Lun Z, Shen J, Wang Y.

Int J Parasitol. 2014 Jun;44(7):475-84. doi: 10.1016/j.ijpara.2014.03.004. Epub 2014 Apr 13.


A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.

Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J, Sasai M, Kayama H, Okamoto T, Huang DC, Soldati-Favre D, Horie K, Takeda J, Takeda K.

Immunity. 2012 Aug 24;37(2):302-13. Epub 2012 Jul 12.


Innate responses to Toxoplasma gondii in mice and humans.

Pifer R, Yarovinsky F.

Trends Parasitol. 2011 Sep;27(9):388-93. doi: 10.1016/ Review.


Toxoplasma gondii infection inhibits Th17-mediated spontaneous development of arthritis in interleukin-1 receptor antagonist-deficient mice.

Washino T, Moroda M, Iwakura Y, Aosai F.

Infect Immun. 2012 Apr;80(4):1437-44. doi: 10.1128/IAI.05680-11. Epub 2012 Jan 30.


Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii.

Béla SR, Dutra MS, Mui E, Montpetit A, Oliveira FS, Oliveira SC, Arantes RM, Antonelli LR, McLeod R, Gazzinelli RT.

Infect Immun. 2012 Dec;80(12):4298-308. doi: 10.1128/IAI.00328-12. Epub 2012 Oct 1.


Co-administration of interleukins 7 and 15 with DNA vaccine improves protective immunity against Toxoplasma gondii.

Chen J, Li ZY, Petersen E, Liu WG, Zhu XQ.

Exp Parasitol. 2016 Mar;162:18-23. doi: 10.1016/j.exppara.2015.12.013. Epub 2015 Dec 17.


NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages.

Matta SK, Patten K, Wang Q, Kim BH, MacMicking JD, Sibley LD.

MBio. 2018 Aug 28;9(4). pii: e01393-18. doi: 10.1128/mBio.01393-18.


Toll-like receptors and their role in host resistance to Toxoplasma gondii.

Yarovinsky F.

Immunol Lett. 2008 Aug 15;119(1-2):17-21. doi: 10.1016/j.imlet.2008.05.007. Epub 2008 Jun 18. Review.


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