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Items: 1 to 20 of 322

1.

Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine.

Hodder AN, Malby RL, Clarke OB, Fairlie WD, Colman PM, Crabb BS, Smith BJ.

J Mol Biol. 2009 Sep 11;392(1):154-65. doi: 10.1016/j.jmb.2009.07.007. Epub 2009 Jul 8.

PMID:
19591843
2.

Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5.

Hodder AN, Drew DR, Epa VC, Delorenzi M, Bourgon R, Miller SK, Moritz RL, Frecklington DF, Simpson RJ, Speed TP, Pike RN, Crabb BS.

J Biol Chem. 2003 Nov 28;278(48):48169-77. Epub 2003 Sep 17.

3.

Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.

Hansen G, Heitmann A, Witt T, Li H, Jiang H, Shen X, Heussler VT, Rennenberg A, Hilgenfeld R.

Structure. 2011 Jul 13;19(7):919-29. doi: 10.1016/j.str.2011.03.025.

4.

Inhibition of malaria parasite development by a cyclic peptide that targets the vital parasite protein SERA5.

Fairlie WD, Spurck TP, McCoubrie JE, Gilson PR, Miller SK, McFadden GI, Malby R, Crabb BS, Hodder AN.

Infect Immun. 2008 Sep;76(9):4332-44. doi: 10.1128/IAI.00278-08. Epub 2008 Jun 30.

5.

Serine repeat antigen (SERA5) is predominantly expressed among the SERA multigene family of Plasmodium falciparum, and the acquired antibody titers correlate with serum inhibition of the parasite growth.

Aoki S, Li J, Itagaki S, Okech BA, Egwang TG, Matsuoka H, Palacpac NM, Mitamura T, Horii T.

J Biol Chem. 2002 Dec 6;277(49):47533-40. Epub 2002 Sep 18.

6.

Antibodies elicited by a virosomally formulated Plasmodium falciparum serine repeat antigen-5 derived peptide detect the processed 47 kDa fragment both in sporozoites and merozoites.

Okitsu SL, Boato F, Mueller MS, Li DB, Vogel D, Westerfeld N, Zurbriggen R, Robinson JA, Pluschke G.

Peptides. 2007 Oct;28(10):2051-60. Epub 2007 Aug 17.

PMID:
17875342
7.

Cross-reactivity studies of an anti-Plasmodium vivax apical membrane antigen 1 monoclonal antibody: binding and structural characterisation.

Igonet S, Vulliez-Le Normand B, Faure G, Riottot MM, Kocken CH, Thomas AW, Bentley GA.

J Mol Biol. 2007 Mar 9;366(5):1523-37. Epub 2006 Dec 16.

PMID:
17229439
8.

Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease.

Ljunggren A, Redzynia I, Alvarez-Fernandez M, Abrahamson M, Mort JS, Krupa JC, Jaskolski M, Bujacz G.

J Mol Biol. 2007 Aug 3;371(1):137-53. Epub 2007 May 10.

PMID:
17561110
9.

Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum.

Hogg T, Nagarajan K, Herzberg S, Chen L, Shen X, Jiang H, Wecke M, Blohmke C, Hilgenfeld R, Schmidt CL.

J Biol Chem. 2006 Sep 1;281(35):25425-37. Epub 2006 Jun 15.

10.
11.

Mapping a common interaction site used by Plasmodium falciparum Duffy binding-like domains to bind diverse host receptors.

Howell DP, Levin EA, Springer AL, Kraemer SM, Phippard DJ, Schief WR, Smith JD.

Mol Microbiol. 2008 Jan;67(1):78-87. Epub 2007 Nov 28.

12.

Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.

Pandey KC, Sijwali PS, Singh A, Na BK, Rosenthal PJ.

J Biol Chem. 2004 Jan 30;279(5):3484-91. Epub 2003 Nov 18.

13.

Exploring the role of putative active site amino acids and pro-region motif of recombinant falcipain-2: a principal hemoglobinase of Plasmodium falciparum.

Kumar A, Dasaradhi PV, Chauhan VS, Malhotra P.

Biochem Biophys Res Commun. 2004 Apr 23;317(1):38-45.

PMID:
15047145
14.

Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain.

Keil C, Maskos K, Than M, Hoopes JT, Huber R, Tan F, Deddish PA, Erdös EG, Skidgel RA, Bode W.

J Mol Biol. 2007 Feb 16;366(2):504-16. Epub 2006 Nov 11.

PMID:
17157876
15.

Disguising itself--insights into Plasmodium falciparum binding and immune evasion from the DBL crystal structure.

Howell DP, Samudrala R, Smith JD.

Mol Biochem Parasitol. 2006 Jul;148(1):1-9. Epub 2006 Apr 4. Review.

PMID:
16621067
16.

Structural basis of the unusual stability and substrate specificity of ervatamin C, a plant cysteine protease from Ervatamia coronaria.

Thakurta PG, Biswas S, Chakrabarti C, Sundd M, Jagannadham MV, Dattagupta JK.

Biochemistry. 2004 Feb 17;43(6):1532-40.

PMID:
14769029
17.

Crystal structure of a novel viral protease with a serine/lysine catalytic dyad mechanism.

Feldman AR, Lee J, Delmas B, Paetzel M.

J Mol Biol. 2006 May 19;358(5):1378-89. Epub 2006 Mar 6.

PMID:
16584747
18.

Inhibitory potential of prodomain of Plasmodium falciparum protease serine repeat antigen 5 for asexual blood stages of parasite.

Alam A, Chauhan VS.

PLoS One. 2012;7(1):e30452. doi: 10.1371/journal.pone.0030452. Epub 2012 Jan 24.

19.

The Plasmodium serine-type SERA proteases display distinct expression patterns and non-essential in vivo roles during life cycle progression of the malaria parasite.

Putrianti ED, Schmidt-Christensen A, Arnold I, Heussler VT, Matuschewski K, Silvie O.

Cell Microbiol. 2010 Jun;12(6):725-39. doi: 10.1111/j.1462-5822.2009.01419.x. Epub 2009 Dec 21.

20.

The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase. A three-domain architecture with a serine protease-like triad at the active site.

Alphey MS, Williams RA, Mottram JC, Coombs GH, Hunter WN.

J Biol Chem. 2003 Nov 28;278(48):48219-27. Epub 2003 Sep 1.

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