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Items: 1 to 20 of 122

1.

Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.

Tu P, Bhasin S, Hruz PW, Herbst KL, Castellani LW, Hua N, Hamilton JA, Guo W.

Diabetes. 2009 Aug;58(8):1739-48. doi: 10.2337/db09-0349. Epub 2009 Jun 9.

2.

Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity.

Guo T, Jou W, Chanturiya T, Portas J, Gavrilova O, McPherron AC.

PLoS One. 2009;4(3):e4937. doi: 10.1371/journal.pone.0004937. Epub 2009 Mar 19.

3.

Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.

Wilkes JJ, Lloyd DJ, Gekakis N.

Diabetes. 2009 May;58(5):1133-43. doi: 10.2337/db08-0245. Epub 2009 Feb 10.

4.

Ces3/TGH deficiency improves dyslipidemia and reduces atherosclerosis in Ldlr(-/-) mice.

Lian J, Quiroga AD, Li L, Lehner R.

Circ Res. 2012 Sep 28;111(8):982-90. Epub 2012 Aug 7.

5.

Cardiovascular protective effects of Casearia sylvestris Swartz in Swiss and C57BL/6 LDLr-null mice undergoing high fat diet.

Frediani Brant NM, Mourão Gasparotto F, de Oliveira Araújo V, Christian Maraschin J, Lima Ribeiro Rde C, Botelho Lourenço EL, Cardozo Junior EL, Gasparotto Junior A.

J Ethnopharmacol. 2014 Jun 11;154(2):419-27. doi: 10.1016/j.jep.2014.04.019. Epub 2014 Apr 18.

PMID:
24747027
6.

AAV-mediated administration of myostatin pro-peptide mutant in adult Ldlr null mice reduces diet-induced hepatosteatosis and arteriosclerosis.

Guo W, Wong S, Bhasin S.

PLoS One. 2013 Aug 1;8(8):e71017. doi: 10.1371/journal.pone.0071017. Print 2013.

7.

Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr-/- Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid.

Samsoondar JP, Burke AC, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Pinkosky SL, Newton RS, Huff MW.

Arterioscler Thromb Vasc Biol. 2017 Apr;37(4):647-656. doi: 10.1161/ATVBAHA.116.308963. Epub 2017 Feb 2.

PMID:
28153881
8.

Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance.

Mulvihill EE, Allister EM, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Markle JM, Hegele RA, Huff MW.

Diabetes. 2009 Oct;58(10):2198-210. doi: 10.2337/db09-0634. Epub 2009 Jul 10.

9.

Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice.

Hasan ST, Zingg JM, Kwan P, Noble T, Smith D, Meydani M.

Atherosclerosis. 2014 Jan;232(1):40-51. doi: 10.1016/j.atherosclerosis.2013.10.016. Epub 2013 Oct 31.

PMID:
24401215
10.

Cholesterol-induced hepatic inflammation does not underlie the predisposition to insulin resistance in dyslipidemic female LDL receptor knockout mice.

Gruben N, Funke A, Kloosterhuis NJ, Schreurs M, Sheedfar F, Havinga R, Houten SM, Shiri-Sverdlov R, van de Sluis B, Kuivenhoven JA, Koonen DP, Hofker MH.

J Diabetes Res. 2015;2015:956854. doi: 10.1155/2015/956854. Epub 2015 Feb 28.

11.
12.

Group 1B phospholipase A₂ inactivation suppresses atherosclerosis and metabolic diseases in LDL receptor-deficient mice.

Hollie NI, Konaniah ES, Goodin C, Hui DY.

Atherosclerosis. 2014 Jun;234(2):377-80. doi: 10.1016/j.atherosclerosis.2014.03.027. Epub 2014 Apr 1.

13.

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

Han S, Liang CP, Westerterp M, Senokuchi T, Welch CL, Wang Q, Matsumoto M, Accili D, Tall AR.

J Clin Invest. 2009 Apr;119(4):1029-41. doi: 10.1172/JCI36523. Epub 2009 Mar 9.

14.

Peroxisome proliferator-activated receptor δ agonist GW1516 attenuates diet-induced aortic inflammation, insulin resistance, and atherosclerosis in low-density lipoprotein receptor knockout mice.

Bojic LA, Burke AC, Chhoker SS, Telford DE, Sutherland BG, Edwards JY, Sawyez CG, Tirona RG, Yin H, Pickering JG, Huff MW.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):52-60. doi: 10.1161/ATVBAHA.113.301830. Epub 2013 Oct 24.

15.

Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir.

Guo W, Wong S, Pudney J, Jasuja R, Hua N, Jiang L, Miller A, Hruz PW, Hamilton JA, Bhasin S.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2028-32. doi: 10.1161/ATVBAHA.109.191304. Epub 2009 Sep 17.

16.

Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice.

Rensing KL, de Jager SC, Stroes ES, Vos M, Twickler MT, Dallinga-Thie GM, de Vries CJ, Kuiper J, Bot I, von der Thüsen JH.

Cardiovasc Res. 2014 Feb 1;101(2):277-87. doi: 10.1093/cvr/cvt252. Epub 2013 Nov 12.

PMID:
24220638
17.

Accelerated atherosclerosis is independent of feeding high fat diet in systemic lupus erythematosus-susceptible LDLr(-/-) mice.

Braun Na, Wade NS, Wakeland EK, Major AS.

Lupus. 2008 Dec;17(12):1070-8. doi: 10.1177/0961203308093551.

18.

Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice.

Zhang C, McFarlane C, Lokireddy S, Masuda S, Ge X, Gluckman PD, Sharma M, Kambadur R.

Diabetologia. 2012 Jan;55(1):183-93. doi: 10.1007/s00125-011-2304-4. Epub 2011 Sep 17. Erratum in: Diabetologia. 2015 Mar;58(3):643.

PMID:
21927895
19.

Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) protein in response to high calorie diet intake.

Bonala S, Lokireddy S, McFarlane C, Patnam S, Sharma M, Kambadur R.

J Biol Chem. 2014 Mar 14;289(11):7654-70. doi: 10.1074/jbc.M113.529925. Epub 2014 Jan 22. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14392.

20.

Apolipoprotein E4 exaggerates diabetic dyslipidemia and atherosclerosis in mice lacking the LDL receptor.

Johnson LA, Arbones-Mainar JM, Fox RG, Pendse AA, Altenburg MK, Kim HS, Maeda N.

Diabetes. 2011 Sep;60(9):2285-94. doi: 10.2337/db11-0466. Epub 2011 Aug 1.

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