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Items: 1 to 20 of 105


Lack of Bax prevents influenza A virus-induced apoptosis and causes diminished viral replication.

McLean JE, Datan E, Matassov D, Zakeri ZF.

J Virol. 2009 Aug;83(16):8233-46. doi: 10.1128/JVI.02672-08. Epub 2009 Jun 3.


Autophagy activation is required for influenza A virus-induced apoptosis and replication.

Yeganeh B, Ghavami S, Rahim MN, Klonisch T, Halayko AJ, Coombs KM.

Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):364-378. doi: 10.1016/j.bbamcr.2017.10.014. Epub 2017 Nov 3.


Nucleoprotein of influenza A virus negatively impacts antiapoptotic protein API5 to enhance E2F1-dependent apoptosis and virus replication.

Mayank AK, Sharma S, Nailwal H, Lal SK.

Cell Death Dis. 2015 Dec 17;6:e2018. doi: 10.1038/cddis.2015.360.


Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.

Wisniewski ML, Werner BG, Hom LG, Anguish LJ, Coffey CM, Parker JS.

J Virol. 2011 Jan;85(1):296-304. doi: 10.1128/JVI.01982-10. Epub 2010 Oct 27.


Toxoplasma gondii infection confers resistance against BimS-induced apoptosis by preventing the activation and mitochondrial targeting of pro-apoptotic Bax.

Hippe D, Weber A, Zhou L, Chang DC, Häcker G, Lüder CG.

J Cell Sci. 2009 Oct 1;122(Pt 19):3511-21. doi: 10.1242/jcs.050963. Epub 2009 Sep 8.


The multidomain proapoptotic molecules Bax and Bak are directly activated by heat.

Pagliari LJ, Kuwana T, Bonzon C, Newmeyer DD, Tu S, Beere HM, Green DR.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17975-80. Epub 2005 Dec 5.


MicroRNA 34a contributes to virus-mediated apoptosis through binding to its target gene Bax in influenza A virus infection.

Fan N, Wang J.

Biomed Pharmacother. 2016 Oct;83:1464-1470. doi: 10.1016/j.biopha.2016.08.049. Epub 2016 Sep 6.


Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.

Lindqvist LM, Heinlein M, Huang DC, Vaux DL.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8512-7. doi: 10.1073/pnas.1406425111. Epub 2014 May 27.


Bak and Bax function to limit adenovirus replication through apoptosis induction.

Cuconati A, Degenhardt K, Sundararajan R, Anschel A, White E.

J Virol. 2002 May;76(9):4547-58.


Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.

Mohan J, Gandhi AA, Bhavya BC, Rashmi R, Karunagaran D, Indu R, Santhoshkumar TR.

J Biol Chem. 2006 Jun 30;281(26):17599-611. Epub 2006 Apr 14.


Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis.

Takahashi Y, Karbowski M, Yamaguchi H, Kazi A, Wu J, Sebti SM, Youle RJ, Wang HG.

Mol Cell Biol. 2005 Nov;25(21):9369-82.


The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak.

Sainski AM, Natesampillai S, Cummins NW, Bren GD, Taylor J, Saenz DT, Poeschla EM, Badley AD.

J Virol. 2011 Aug;85(16):7965-75. doi: 10.1128/JVI.02515-10. Epub 2011 Jun 8.


Bik Mediates Caspase-Dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection.

Mebratu YA, Tipper J, Chand HS, Walton S, Harrod KS, Tesfaigzi Y.

Am J Respir Cell Mol Biol. 2016 May;54(5):664-73. doi: 10.1165/rcmb.2015-0133OC.


Indirect effects of Bax and Bak initiate the mitochondrial alterations that lead to cytochrome c release during arsenic trioxide-induced apoptosis.

Nutt LK, Gogvadze V, Uthaisang W, Mirnikjoo B, McConkey DJ, Orrenius S.

Cancer Biol Ther. 2005 Apr;4(4):459-67. Epub 2005 Apr 28.


Novel pandemic influenza A (H1N1) virus infection modulates apoptotic pathways that impact its replication in A549 cells.

Wang X, Tan J, Zoueva O, Zhao J, Ye Z, Hewlett I.

Microbes Infect. 2014 Mar;16(3):178-86. doi: 10.1016/j.micinf.2013.11.003. Epub 2013 Nov 18.


Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).

Lindenboim L, Blacher E, Borner C, Stein R.

Cell Death Differ. 2010 Feb;17(2):346-59. doi: 10.1038/cdd.2009.145. Epub 2009 Oct 9.

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