Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 123


Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism.

James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, Gaylor DW.

FASEB J. 2009 Aug;23(8):2374-83. doi: 10.1096/fj.08-128926. Epub 2009 Mar 23.


Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study.

Rose S, Bennuri SC, Wynne R, Melnyk S, James SJ, Frye RE.

FASEB J. 2017 Mar;31(3):904-909. doi: 10.1096/fj.201601004R. Epub 2016 Nov 18.


Brain region-specific glutathione redox imbalance in autism.

Chauhan A, Audhya T, Chauhan V.

Neurochem Res. 2012 Aug;37(8):1681-9. doi: 10.1007/s11064-012-0775-4. Epub 2012 Apr 12.


Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort.

Rose S, Frye RE, Slattery J, Wynne R, Tippett M, Pavliv O, Melnyk S, James SJ.

PLoS One. 2014 Jan 8;9(1):e85436. doi: 10.1371/journal.pone.0085436. eCollection 2014.


Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain.

Rose S, Melnyk S, Pavliv O, Bai S, Nick TG, Frye RE, James SJ.

Transl Psychiatry. 2012 Jul 10;2:e134. doi: 10.1038/tp.2012.61.


Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines.

Rose S, Frye RE, Slattery J, Wynne R, Tippett M, Melnyk S, James SJ.

Transl Psychiatry. 2014 Apr 1;4:e377. doi: 10.1038/tp.2014.15. Erratum in: Transl Psychiatry. 2015;5:e526.


Redox metabolism abnormalities in autistic children associated with mitochondrial disease.

Frye RE, Delatorre R, Taylor H, Slattery J, Melnyk S, Chowdhury N, James SJ.

Transl Psychiatry. 2013 Jun 18;3:e273. doi: 10.1038/tp.2013.51.


Degree of glutathione deficiency and redox imbalance depend on subtype of mitochondrial disease and clinical status.

Enns GM, Moore T, Le A, Atkuri K, Shah MK, Cusmano-Ozog K, Niemi AK, Cowan TM.

PLoS One. 2014 Jun 18;9(6):e100001. doi: 10.1371/journal.pone.0100001. eCollection 2014.


Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE.

Beer SM, Taylor ER, Brown SE, Dahm CC, Costa NJ, Runswick MJ, Murphy MP.

J Biol Chem. 2004 Nov 12;279(46):47939-51. Epub 2004 Aug 30.


Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism.

Rose S, Melnyk S, Trusty TA, Pavliv O, Seidel L, Li J, Nick T, James SJ.

Autism Res Treat. 2012;2012:986519. doi: 10.1155/2012/986519. Epub 2011 Nov 24.


Bisphenol A induces oxidative stress and mitochondrial dysfunction in lymphoblasts from children with autism and unaffected siblings.

Kaur K, Chauhan V, Gu F, Chauhan A.

Free Radic Biol Med. 2014 Nov;76:25-33. doi: 10.1016/j.freeradbiomed.2014.07.030. Epub 2014 Aug 4.


Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.

James SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, Neubrander JA.

Am J Clin Nutr. 2004 Dec;80(6):1611-7.


Glutathione redox state regulates mitochondrial reactive oxygen production.

Shen D, Dalton TP, Nebert DW, Shertzer HG.

J Biol Chem. 2005 Jul 8;280(27):25305-12. Epub 2005 May 9.


Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism.

James SJ, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, Hubanks A, Gaylor DW.

Am J Clin Nutr. 2009 Jan;89(1):425-30. doi: 10.3945/ajcn.2008.26615. Epub 2008 Dec 3.


Impaired synthesis and antioxidant defense of glutathione in the cerebellum of autistic subjects: alterations in the activities and protein expression of glutathione-related enzymes.

Gu F, Chauhan V, Chauhan A.

Free Radic Biol Med. 2013 Dec;65:488-96. doi: 10.1016/j.freeradbiomed.2013.07.021. Epub 2013 Jul 26.


Evaluation of a dithiocarbamate derivative as a model of thiol oxidative stress in H9c2 rat cardiomyocytes.

Xie J, Potter A, Xie W, Lynch C, Seefeldt T.

Free Radic Biol Med. 2014 May;70:214-22. doi: 10.1016/j.freeradbiomed.2014.02.022. Epub 2014 Mar 4.


Inhibition of rat PC12 cell calpain activity by glutathione, oxidized glutathione and nitric oxide.

Rackoff J, Yang Q, DePetrillo PB.

Neurosci Lett. 2001 Sep 28;311(2):129-32.


Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis.

Circu ML, Rodriguez C, Maloney R, Moyer MP, Aw TY.

Free Radic Biol Med. 2008 Mar 1;44(5):768-78. doi: 10.1016/j.freeradbiomed.2007.09.011. Epub 2007 Sep 25.


Seizure-induced changes in mitochondrial redox status.

Liang LP, Patel M.

Free Radic Biol Med. 2006 Jan 15;40(2):316-22. Epub 2005 Oct 14.


Supplemental Content

Support Center