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Items: 1 to 20 of 110


Host responses to wild-type and attenuated herpes simplex virus infection in the absence of Stat1.

Pasieka TJ, Cilloniz C, Lu B, Teal TH, Proll SC, Katze MG, Leib DA.

J Virol. 2009 Mar;83(5):2075-87. doi: 10.1128/JVI.02007-08. Epub 2008 Dec 24.


Functional genomics reveals an essential and specific role for Stat1 in protection of the central nervous system following herpes simplex virus corneal infection.

Pasieka TJ, Cilloniz C, Carter VS, Rosato P, Katze MG, Leib DA.

J Virol. 2011 Dec;85(24):12972-81. doi: 10.1128/JVI.06032-11. Epub 2011 Oct 12.


Herpes simplex virus virion host shutoff (vhs) activity alters periocular disease in mice.

Smith TJ, Ackland-Berglund CE, Leib DA.

J Virol. 2000 Apr;74(8):3598-604.


The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.

Cotter CR, Kim WK, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM.

J Virol. 2011 Dec;85(23):12662-72. doi: 10.1128/JVI.05557-11. Epub 2011 Sep 21.


Subclinical Herpes Simplex Virus Type 1 Infections Provide Site-Specific Resistance to an Unrelated Pathogen.

Rowe AM, Yun H, Treat BR, Kinchington PR, Hendricks RL.

J Immunol. 2017 Feb 15;198(4):1706-1717. doi: 10.4049/jimmunol.1601310. Epub 2017 Jan 6.


Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.

Smith TJ, Morrison LA, Leib DA.

J Virol. 2002 Mar;76(5):2054-61.


Enhanced pathogenesis of an attenuated herpes simplex virus for mice lacking Stat1.

Pasieka TJ, Lu B, Leib DA.

J Virol. 2008 Jun;82(12):6052-5. doi: 10.1128/JVI.00297-08. Epub 2008 Apr 9.


Immune- and Nonimmune-Compartment-Specific Interferon Responses Are Critical Determinants of Herpes Simplex Virus-Induced Generalized Infections and Acute Liver Failure.

Parker ZM, Pasieka TJ, Parker GA, Leib DA.

J Virol. 2016 Nov 14;90(23):10789-10799. doi: 10.1128/JVI.01473-16. Print 2016 Dec 1.


Functional hierarchy of herpes simplex virus type-1 membrane proteins in corneal infection and virus transmission to ganglionic neurons.

Kim IJ, Saied AA, Chouljenko VN, Subramanian R, Kousoulas KG.

Curr Eye Res. 2014 Dec;39(12):1169-77. doi: 10.3109/02713683.2014.906626. Epub 2014 Apr 21.


Corneal replication is an interferon response-independent bottleneck for virulence of herpes simplex virus 1 in the absence of virion host shutoff.

Pasieka TJ, Menachery VD, Rosato PC, Leib DA.

J Virol. 2012 Jul;86(14):7692-5. doi: 10.1128/JVI.00761-12. Epub 2012 May 2.


Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice.

Korom M, Wylie KM, Morrison LA.

J Virol. 2008 Apr;82(7):3642-53. doi: 10.1128/JVI.02409-07. Epub 2008 Jan 30.


Therapeutic vaccination with vhs(-) herpes simplex virus reduces the severity of recurrent herpetic stromal keratitis in mice.

Keadle TL, Laycock KA, Morris JL, Leib DA, Morrison LA, Pepose JS, Stuart PM.

J Gen Virol. 2002 Oct;83(Pt 10):2361-5.


Interferon regulatory factor 3-dependent pathways are critical for control of herpes simplex virus type 1 central nervous system infection.

Menachery VD, Pasieka TJ, Leib DA.

J Virol. 2010 Oct;84(19):9685-94. doi: 10.1128/JVI.00706-10. Epub 2010 Jul 21.


Functional genomic analysis of herpes simplex virus type 1 counteraction of the host innate response.

Pasieka TJ, Baas T, Carter VS, Proll SC, Katze MG, Leib DA.

J Virol. 2006 Aug;80(15):7600-12.


Role of CD8+ T cells and lymphoid dendritic cells in protection from ocular herpes simplex virus 1 challenge in immunized mice.

Matundan H, Mott KR, Ghiasi H.

J Virol. 2014 Jul;88(14):8016-27. doi: 10.1128/JVI.00913-14. Epub 2014 May 7.

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