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Items: 1 to 20 of 102

1.

Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.

Liu X, Fitzgerald K, Kurt-Jones E, Finberg R, Knipe DM.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11335-9. doi: 10.1073/pnas.0801617105. Epub 2008 Aug 5.

2.

The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway.

Cai M, Li M, Wang K, Wang S, Lu Q, Yan J, Mossman KL, Lin R, Zheng C.

PLoS One. 2013;8(1):e54586. doi: 10.1371/journal.pone.0054586. Epub 2013 Jan 28.

3.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

4.

The TLR2 ligand FSL-1 and the TLR5 ligand Flagellin mediate pro-inflammatory and pro-labour response via MyD88/TRAF6/NF-κB-dependent signalling.

Lim R, Barker G, Lappas M.

Am J Reprod Immunol. 2014 May;71(5):401-17. doi: 10.1111/aji.12229. Epub 2014 Mar 17.

PMID:
24635133
5.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

6.

A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions.

Noels H, van Loo G, Hagens S, Broeckx V, Beyaert R, Marynen P, Baens M.

J Biol Chem. 2007 Apr 6;282(14):10180-9. Epub 2007 Feb 7.

7.

Epstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-κB signaling during productive replication.

Saito S, Murata T, Kanda T, Isomura H, Narita Y, Sugimoto A, Kawashima D, Tsurumi T.

J Virol. 2013 Apr;87(7):4060-70. doi: 10.1128/JVI.02020-12. Epub 2013 Jan 30.

8.
9.

Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination.

Sen J, Liu X, Roller R, Knipe DM.

Virology. 2013 May 10;439(2):65-73. doi: 10.1016/j.virol.2013.01.026. Epub 2013 Mar 7.

10.

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta.

Jiang Z, Mak TW, Sen G, Li X.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3533-8. Epub 2004 Feb 24.

11.

TRAF6 negatively regulates TNFalpha-induced NF-kappaB activation.

Funakoshi-Tago M, Kamada N, Shimizu T, Hashiguchi Y, Tago K, Sonoda Y, Kasahara T.

Cytokine. 2009 Feb;45(2):72-9. doi: 10.1016/j.cyto.2008.10.010. Epub 2008 Dec 16.

PMID:
19091594
12.

The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.

Cotter CR, Kim WK, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM.

J Virol. 2011 Dec;85(23):12662-72. doi: 10.1128/JVI.05557-11. Epub 2011 Sep 21.

13.

Interleukin-8 induces nuclear transcription factor-kappaB through a TRAF6-dependent pathway.

Manna SK, Ramesh GT.

J Biol Chem. 2005 Feb 25;280(8):7010-21. Epub 2004 Dec 9.

15.

Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.

Matta H, Gopalakrishnan R, Graham C, Tolani B, Khanna A, Yi H, Suo Y, Chaudhary PM.

PLoS One. 2012;7(5):e36601. doi: 10.1371/journal.pone.0036601. Epub 2012 May 8.

16.

STP-C, an oncoprotein of herpesvirus saimiri augments the activation of NF-kappaB through ubiquitination of TRAF6.

Chung YH, Jhun BH, Ryu SC, Kim HS, Kim CM, Kim BS, Kim YO, Lee SJ.

J Biochem Mol Biol. 2007 May 31;40(3):341-8.

PMID:
17562285
18.

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination.

Zhang X, Zhang J, Zhang L, van Dam H, ten Dijke P.

Cell Res. 2013 Mar;23(3):366-77. doi: 10.1038/cr.2013.21. Epub 2013 Feb 5.

19.

Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling.

Tanishima M, Takashima S, Honda A, Yasuda D, Tanikawa T, Ishii S, MaruYama T.

J Biol Chem. 2017 Oct 20;292(42):17250-17257. doi: 10.1074/jbc.M117.813899. Epub 2017 Sep 7.

20.

Suppression of Host Innate Immune Response by Hepatitis C Virus via Induction of Autophagic Degradation of TRAF6.

Chan ST, Lee J, Narula M, Ou JJ.

J Virol. 2016 Nov 14;90(23):10928-10935. doi: 10.1128/JVI.01365-16. Print 2016 Dec 1.

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