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Items: 1 to 20 of 96

1.

Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock.

Shanley TP, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A, Kalyanaraman M, Tofil NM, Penfil S, Monaco M, Odoms K, Barnes M, Sakthivel B, Aronow BJ, Wong HR.

Mol Med. 2007 Sep-Oct;13(9-10):495-508.

2.

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.

Wong HR, Cvijanovich N, Allen GL, Lin R, Anas N, Meyer K, Freishtat RJ, Monaco M, Odoms K, Sakthivel B, Shanley TP; Genomics of Pediatric SIRS/Septic Shock Investigators.

Crit Care Med. 2009 May;37(5):1558-66. doi: 10.1097/CCM.0b013e31819fcc08.

3.

Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome.

Wong HR, Shanley TP, Sakthivel B, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A, Kalyanaraman M, Tofil NM, Penfil S, Monaco M, Tagavilla MA, Odoms K, Dunsmore K, Barnes M, Aronow BJ; Genomics of Pediatric SIRS/Septic Shock Investigators.

Physiol Genomics. 2007 Jul 18;30(2):146-55. Epub 2007 Mar 20.

4.

Leukocyte subset-derived genomewide expression profiles in pediatric septic shock.

Wong HR, Freishtat RJ, Monaco M, Odoms K, Shanley TP.

Pediatr Crit Care Med. 2010 May;11(3):349-55. doi: 10.1097/PCC.0b013e3181c519b4.

5.

Validating the genomic signature of pediatric septic shock.

Cvijanovich N, Shanley TP, Lin R, Allen GL, Thomas NJ, Checchia P, Anas N, Freishtat RJ, Monaco M, Odoms K, Sakthivel B, Wong HR; Genomics of Pediatric SIRS/Septic Shock Investigators.

Physiol Genomics. 2008 Jun 12;34(1):127-34. doi: 10.1152/physiolgenomics.00025.2008. Epub 2008 May 6.

6.

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock.

Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Banschbach S, Beckman E, Howard K, Frank E, Harmon K, Wong HR.

Crit Care. 2014 Nov 19;18(6):623. doi: 10.1186/s13054-014-0623-9.

7.

Identification of pediatric septic shock subclasses based on genome-wide expression profiling.

Wong HR, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Willson DF, Freishtat RJ, Anas N, Meyer K, Checchia PA, Monaco M, Odom K, Shanley TP.

BMC Med. 2009 Jul 22;7:34. doi: 10.1186/1741-7015-7-34.

8.

The influence of developmental age on the early transcriptomic response of children with septic shock.

Wynn JL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Banschbach S, Beckman E, Wong HR.

Mol Med. 2011;17(11-12):1146-56. doi: 10.2119/molmed.2011.00169. Epub 2011 Jul 5.

9.

Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock.

Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Weiss SL, Shanley TP, Bigham MT, Banschbach S, Beckman E, Harmon K, Zimmerman JJ.

Am J Respir Crit Care Med. 2014 Apr 15;189(8):940-6. doi: 10.1164/rccm.201401-0171OC.

10.

Differential expression of the Nrf2-linked genes in pediatric septic shock.

Grunwell JR, Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Howard K, Frank E, Harmon K, Wong HR.

Crit Care. 2015 Sep 17;19:327. doi: 10.1186/s13054-015-1052-0.

11.

Genetics and genomics in pediatric septic shock.

Wong HR.

Crit Care Med. 2012 May;40(5):1618-26. doi: 10.1097/CCM.0b013e318246b546. Review.

12.
13.

Developing a clinically feasible personalized medicine approach to pediatric septic shock.

Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Shekhar RS, Gertz S, Dawson E, Howard K, Harmon K, Beckman E, Frank E, Lindsell CJ.

Am J Respir Crit Care Med. 2015 Feb 1;191(3):309-15. doi: 10.1164/rccm.201410-1864OC.

14.

Genome-wide expression profiling in pediatric septic shock.

Wong HR.

Pediatr Res. 2013 Apr;73(4 Pt 2):564-9. doi: 10.1038/pr.2013.11. Epub 2013 Jan 17. Review.

15.

Validation of a gene expression-based subclassification strategy for pediatric septic shock.

Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Wheeler DS, Doughty LA, Tegtmeyer K, Poynter SE, Kaplan JM, Chima RS, Stalets E, Basu RK, Varisco BM, Barr FE.

Crit Care Med. 2011 Nov;39(11):2511-7. doi: 10.1097/CCM.0b013e3182257675.

16.

Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients.

Pachot A, Monneret G, Brion A, Venet F, Bohé J, Bienvenu J, Mougin B, Lepape A.

Crit Care Med. 2005 Jan;33(1):31-8; discussion 236-7.

PMID:
15644645
17.

Pediatric septic shock treatment: new clues from genomic profiling.

Wong HR.

Pharmacogenomics. 2007 Oct;8(10):1287-90. No abstract available.

18.

Systemic transcriptional analysis in survivor and non-survivor septic shock patients: a preliminary study.

Pachot A, Lepape A, Vey S, Bienvenu J, Mougin B, Monneret G.

Immunol Lett. 2006 Jul 15;106(1):63-71. Epub 2006 May 17.

PMID:
16765452
19.

Association of angiotensin II type 1 receptor-associated protein gene polymorphism with increased mortality in septic shock.

Nakada TA, Russell JA, Boyd JH, McLaughlin L, Nakada E, Thair SA, Hirasawa H, Oda S, Walley KR.

Crit Care Med. 2011 Jul;39(7):1641-8. doi: 10.1097/CCM.0b013e318218665a.

PMID:
21423001
20.

Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase.

Pathan N, Franklin JL, Eleftherohorinou H, Wright VJ, Hemingway CA, Waddell SJ, Griffiths M, Dennis JL, Relman DA, Harding SE, Levin M.

Crit Care Med. 2011 Jul;39(7):1692-711. doi: 10.1097/CCM.0b013e3182186d27.

PMID:
21494108

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