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Items: 1 to 20 of 69

1.

BRCA2 function and the central nervous system.

Frappart PO, McKinnon PJ.

Cell Cycle. 2007 Oct 15;6(20):2453-7. Epub 2007 Jul 23.

PMID:
17786054
2.

BRCA2 is required for neurogenesis and suppression of medulloblastoma.

Frappart PO, Lee Y, Lamont J, McKinnon PJ.

EMBO J. 2007 Jun 6;26(11):2732-42. Epub 2007 May 3.

3.

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.

PMID:
18473729
4.

Deficiency in BRCA2 leads to increase in non-conservative homologous recombination.

Larminat F, Germanier M, Papouli E, Defais M.

Oncogene. 2002 Aug 1;21(33):5188-92.

5.

Lower level of BRCA2 protein in heterozygous mutation carriers is correlated with an increase in DNA double strand breaks and an impaired DSB repair.

Arnold K, Kim MK, Frerk K, Edler L, Savelyeva L, Schmezer P, Wiedemeyer R.

Cancer Lett. 2006 Nov 8;243(1):90-100. Epub 2006 Jan 31.

PMID:
16448746
6.

BRCA2: a universal recombinase regulator.

Thorslund T, West SC.

Oncogene. 2007 Dec 10;26(56):7720-30. Review.

PMID:
18066084
7.

Responding to DNA double strand breaks in the nervous system.

Lee Y, McKinnon PJ.

Neuroscience. 2007 Apr 14;145(4):1365-74. Epub 2006 Aug 23. Review.

PMID:
16934412
8.
9.

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition.

Tutt A, Ashworth A.

Trends Mol Med. 2002 Dec;8(12):571-6. Review.

PMID:
12470990
10.

Absence of major defects in non-homologous DNA end joining in human breast cancer cell lines.

Mérel P, Prieur A, Pfeiffer P, Delattre O.

Oncogene. 2002 Aug 15;21(36):5654-9.

11.

PALB2 is an integral component of the BRCA complex required for homologous recombination repair.

Sy SM, Huen MS, Chen J.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7155-60. doi: 10.1073/pnas.0811159106. Epub 2009 Apr 15.

12.

BRCA2 functions: from DNA repair to replication fork stabilization.

Fradet-Turcotte A, Sitz J, Grapton D, Orthwein A.

Endocr Relat Cancer. 2016 Oct;23(10):T1-T17. doi: 10.1530/ERC-16-0297. Epub 2016 Aug 16. Review.

13.

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

Xia B, Sheng Q, Nakanishi K, Ohashi A, Wu J, Christ N, Liu X, Jasin M, Couch FJ, Livingston DM.

Mol Cell. 2006 Jun 23;22(6):719-29.

14.

Microcephalin regulates BRCA2 and Rad51-associated DNA double-strand break repair.

Wu X, Mondal G, Wang X, Wu J, Yang L, Pankratz VS, Rowley M, Couch FJ.

Cancer Res. 2009 Jul 1;69(13):5531-6. doi: 10.1158/0008-5472.CAN-08-4834. Epub 2009 Jun 23.

15.
17.

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.

Yang H, Jeffrey PD, Miller J, Kinnucan E, Sun Y, Thoma NH, Zheng N, Chen PL, Lee WH, Pavletich NP.

Science. 2002 Sep 13;297(5588):1837-48.

18.

Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions.

Saeki H, Siaud N, Christ N, Wiegant WW, van Buul PP, Han M, Zdzienicka MZ, Stark JM, Jasin M.

Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8768-73. Epub 2006 May 26.

19.

BRCA2 is required for homology-directed repair of chromosomal breaks.

Moynahan ME, Pierce AJ, Jasin M.

Mol Cell. 2001 Feb;7(2):263-72.

20.

Effect of the expression of BRCA2 on spontaneous homologous recombination and DNA damage-induced nuclear foci in Saccharomyces cerevisiae.

Spugnesi L, Balia C, Collavoli A, Falaschi E, Quercioli V, Caligo MA, Galli A.

Mutagenesis. 2013 Mar;28(2):187-95. doi: 10.1093/mutage/ges069. Epub 2013 Jan 16.

PMID:
23328489

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