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Influenza A virus non-structural protein 1 (NS1) interacts with cellular multifunctional protein nucleolin during infection.

Murayama R, Harada Y, Shibata T, Kuroda K, Hayakawa S, Shimizu K, Tanaka T.

Biochem Biophys Res Commun. 2007 Nov 3;362(4):880-5. Epub 2007 Aug 27.


Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin.

Melén K, Tynell J, Fagerlund R, Roussel P, Hernandez-Verdun D, Julkunen I.

Virol J. 2012 Aug 21;9:167. doi: 10.1186/1743-422X-9-167.


[Study progress of NS1 protein of influenza A virus].

Li JL, Zhang WP, Bi DR.

Wei Sheng Wu Xue Bao. 2007 Aug;47(4):729-33. Review. Chinese.


Characterization of the interaction of influenza virus NS1 with Akt.

Matsuda M, Suizu F, Hirata N, Miyazaki T, Obuse C, Noguchi M.

Biochem Biophys Res Commun. 2010 May 7;395(3):312-7. doi: 10.1016/j.bbrc.2010.03.166. Epub 2010 Apr 1.


Influenza virus A/Beijing/501/2009(H1N1) NS1 interacts with β-tubulin and induces disruption of the microtubule network and apoptosis on A549 cells.

Han X, Li Z, Chen H, Wang H, Mei L, Wu S, Zhang T, Liu B, Lin X.

PLoS One. 2012;7(11):e48340. doi: 10.1371/journal.pone.0048340. Epub 2012 Nov 6.


Interaction of avian influenza virus NS1 protein and nucleolar and coiled-body phosphoprotein 1.

Zhu C, Zheng F, Sun T, Duan Y, Cao J, Feng H, Shang L, Zhu Y, Liu H.

Virus Genes. 2013 Apr;46(2):287-92. doi: 10.1007/s11262-012-0849-z. Epub 2012 Nov 28.


Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode.

Chien CY, Xu Y, Xiao R, Aramini JM, Sahasrabudhe PV, Krug RM, Montelione GT.

Biochemistry. 2004 Feb 24;43(7):1950-62.


Direct interaction between nucleolin and hepatitis C virus NS5B.

Hirano M, Kaneko S, Yamashita T, Luo H, Qin W, Shirota Y, Nomura T, Kobayashi K, Murakami S.

J Biol Chem. 2003 Feb 14;278(7):5109-15. Epub 2002 Nov 9.


Development of an HTS assay for the search of anti-influenza agents targeting the interaction of viral RNA with the NS1 protein.

Maroto M, Fernandez Y, Ortin J, Pelaez F, Cabello MA.

J Biomol Screen. 2008 Aug;13(7):581-90. doi: 10.1177/1087057108318754. Epub 2008 Jul 1.


Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses.

Yin C, Khan JA, Swapna GV, Ertekin A, Krug RM, Tong L, Montelione GT.

J Biol Chem. 2007 Jul 13;282(28):20584-92. Epub 2007 May 1.


Influenza A virus proteins PB1 and NS1 are subject to functionally important phosphorylation by protein kinase C.

Mahmoudian S, Auerochs S, Gröne M, Marschall M.

J Gen Virol. 2009 Jun;90(Pt 6):1392-7. doi: 10.1099/vir.0.009050-0. Epub 2009 Mar 4.


Direct interaction of cellular hnRNP-F and NS1 of influenza A virus accelerates viral replication by modulation of viral transcriptional activity and host gene expression.

Lee JH, Kim SH, Pascua PN, Song MS, Baek YH, Jin X, Choi JK, Kim CJ, Kim H, Choi YK.

Virology. 2010 Feb 5;397(1):89-99. doi: 10.1016/j.virol.2009.10.041. Epub 2009 Nov 18. Retraction in: Virology. 2013 Feb 5;436(1):245.


The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication.

de Chassey B, Aublin-Gex A, Ruggieri A, Meyniel-Schicklin L, Pradezynski F, Davoust N, Chantier T, Tafforeau L, Mangeot PE, Ciancia C, Perrin-Cocon L, Bartenschlager R, André P, Lotteau V.

PLoS Pathog. 2013;9(7):e1003440. doi: 10.1371/journal.ppat.1003440. Epub 2013 Jul 4.


Human Staufen1 protein interacts with influenza virus ribonucleoproteins and is required for efficient virus multiplication.

de Lucas S, Peredo J, Marión RM, Sánchez C, Ortín J.

J Virol. 2010 Aug;84(15):7603-12. doi: 10.1128/JVI.00504-10. Epub 2010 May 26.


Impairment of the Staufen1-NS1 interaction reduces influenza viral replication.

Lee JH, Oh JY, Pascua PN, Kim EG, Choi YK, Kim HK.

Biochem Biophys Res Commun. 2011 Oct 14;414(1):153-8. doi: 10.1016/j.bbrc.2011.09.042. Epub 2011 Sep 16.


Large-scale analysis of influenza A virus sequences reveals potential drug target sites of non-structural proteins.

Darapaneni V, Prabhaker VK, Kukol A.

J Gen Virol. 2009 Sep;90(Pt 9):2124-33. doi: 10.1099/vir.0.011270-0. Epub 2009 May 6.


New regulatory mechanisms for the intracellular localization and trafficking of influenza A virus NS1 protein revealed by comparative analysis of A/PR/8/34 and A/Sydney/5/97.

Han H, Cui ZQ, Wang W, Zhang ZP, Wei HP, Zhou YF, Zhang XE.

J Gen Virol. 2010 Dec;91(Pt 12):2907-17. doi: 10.1099/vir.0.024943-0. Epub 2010 Sep 8.


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