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Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii.

Debierre-Grockiego F, Campos MA, Azzouz N, Schmidt J, Bieker U, Resende MG, Mansur DS, Weingart R, Schmidt RR, Golenbock DT, Gazzinelli RT, Schwarz RT.

J Immunol. 2007 Jul 15;179(2):1129-37.


TLR2 as an essential molecule for protective immunity against Toxoplasma gondii infection.

Mun HS, Aosai F, Norose K, Chen M, Piao LX, Takeuchi O, Akira S, Ishikura H, Yano A.

Int Immunol. 2003 Sep;15(9):1081-7.


The role of IFN-gamma and Toll-like receptors in nephropathy induced by Toxoplasma gondii infection.

Kudo M, Aosai F, Mun HS, Norose K, Akira S, Iwakura Y, Yano A.

Microbiol Immunol. 2004;48(8):617-28.


Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis.

Furuta T, Kikuchi T, Akira S, Watanabe N, Yoshikawa Y.

Int Immunol. 2006 Dec;18(12):1655-62. Epub 2006 Oct 11.


Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.

Romics L Jr, Dolganiuc A, Velayudham A, Kodys K, Mandrekar P, Golenbock D, Kurt-Jones E, Szabo G.

J Leukoc Biol. 2005 Dec;78(6):1255-64. Epub 2005 Oct 4.


Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A.

J Immunol. 2002 Jun 15;168(12):5997-6001.


Roles of glycosylphosphatidylinositols of Toxoplasma gondii. Induction of tumor necrosis factor-alpha production in macrophages.

Debierre-Grockiego F, Azzouz N, Schmidt J, Dubremetz JF, Geyer H, Geyer R, Weingart R, Schmidt RR, Schwarz RT.

J Biol Chem. 2003 Aug 29;278(35):32987-93. Epub 2003 Jun 18.


MyD88 is dispensable for resistance to Paracoccidioides brasiliensis in a murine model of blood-borne disseminated infection.

González A, Yáñez A, Gozalbo D, Gil ML.

FEMS Immunol Med Microbiol. 2008 Dec;54(3):365-74. doi: 10.1111/j.1574-695X.2008.00487.x.


Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E.

J Immunol. 2007 Jan 15;178(2):1068-76.


Binding of Toxoplasma gondii glycosylphosphatidylinositols to galectin-3 is required for their recognition by macrophages.

Debierre-Grockiego F, Niehus S, Coddeville B, Elass E, Poirier F, Weingart R, Schmidt RR, Mazurier J, Guérardel Y, Schwarz RT.

J Biol Chem. 2010 Oct 22;285(43):32744-50. doi: 10.1074/jbc.M110.137588. Epub 2010 Aug 20.


Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.

Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT.

J Biol Chem. 2004 Dec 24;279(52):54405-15. Epub 2004 Oct 13.


TLR2-, TLR4- and Myd88-independent acquired humoral and cellular immunity against Salmonella enterica serovar Typhimurium.

Seibert SA, Mex P, Köhler A, Kaufmann SH, Mittrücker HW.

Immunol Lett. 2010 Jan 4;127(2):126-34. doi: 10.1016/j.imlet.2009.10.008. Epub 2009 Nov 4.


Proinflammatory cytokine production in liver regeneration is Myd88-dependent, but independent of Cd14, Tlr2, and Tlr4.

Campbell JS, Riehle KJ, Brooling JT, Bauer RL, Mitchell C, Fausto N.

J Immunol. 2006 Feb 15;176(4):2522-8.


Synergism of toll-like receptor 2 (TLR2), TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-alpha in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice.

Jung YO, Cho ML, Lee SY, Oh HJ, Park JS, Park MK, Park MJ, Ju JH, Kim SI, Park SH, Kim HY, Min JK.

Immunol Lett. 2009 Apr 27;123(2):138-43. doi: 10.1016/j.imlet.2009.03.004. Epub 2009 Mar 21.


TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker.

Jung DY, Lee H, Jung BY, Ock J, Lee MS, Lee WH, Suk K.

J Immunol. 2005 May 15;174(10):6467-76.


TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis.

Leendertse M, Willems RJ, Giebelen IA, van den Pangaart PS, Wiersinga WJ, de Vos AF, Florquin S, Bonten MJ, van der Poll T.

J Immunol. 2008 Apr 1;180(7):4865-74.


Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.

Campos MA, Closel M, Valente EP, Cardoso JE, Akira S, Alvarez-Leite JI, Ropert C, Gazzinelli RT.

J Immunol. 2004 Feb 1;172(3):1711-8.

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