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ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques.

Wågsäter D, Björk H, Zhu C, Björkegren J, Valen G, Hamsten A, Eriksson P.

Atherosclerosis. 2008 Feb;196(2):514-22. Epub 2007 Jul 2.


The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-β and requires Smads, p38 mitogen-activated protein kinase and c-Jun.

Salter RC, Arnaoutakis K, Michael DR, Singh NN, Ashlin TG, Buckley ML, Kwan AP, Ramji DP.

Int J Biochem Cell Biol. 2011 May;43(5):805-11. doi: 10.1016/j.biocel.2011.02.005. Epub 2011 Feb 18.


ADAMTS-1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes.

Cross AK, Haddock G, Stock CJ, Allan S, Surr J, Bunning RA, Buttle DJ, Woodroofe MN.

Brain Res. 2006 May 9;1088(1):19-30. Epub 2006 Apr 21.


Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.

Tian Y, Yuan W, Fujita N, Wang J, Wang H, Shapiro IM, Risbud MV.

Am J Pathol. 2013 Jun;182(6):2310-21. doi: 10.1016/j.ajpath.2013.02.037. Epub 2013 Apr 17.


The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells.

Corps AN, Jones GC, Harrall RL, Curry VA, Hazleman BL, Riley GP.

Matrix Biol. 2008 Jun;27(5):393-401. doi: 10.1016/j.matbio.2008.02.002. Epub 2008 Apr 2.


Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage.

Naito S, Shiomi T, Okada A, Kimura T, Chijiiwa M, Fujita Y, Yatabe T, Komiya K, Enomoto H, Fujikawa K, Okada Y.

Pathol Int. 2007 Nov;57(11):703-11.


Expression of ADAMTS-1, ADAMTS-4, ADAMTS-5 and TIMP3 by hepatocellular carcinoma cell lines.

Turner SL, Mangnall D, Bird NC, Bunning RA, Blair-Zajdel ME.

Int J Oncol. 2012 Sep;41(3):1043-9. doi: 10.3892/ijo.2012.1525. Epub 2012 Jun 20.


IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc.

Sun Z, Yin Z, Liu C, Liang H, Jiang M, Tian J.

J Orthop Surg Res. 2015 Oct 6;10:159. doi: 10.1186/s13018-015-0296-3.


Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.

Lee CW, Hwang I, Park CS, Lee H, Park DW, Kang SJ, Lee SW, Kim YH, Park SW, Park SJ.

J Thromb Thrombolysis. 2012 May;33(4):362-70. doi: 10.1007/s11239-011-0673-7.


IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway.

Alper M, Kockar F.

Mol Cell Biochem. 2014 Aug;393(1-2):165-75. doi: 10.1007/s11010-014-2056-9. Epub 2014 Apr 22.


Differential effects of ADAMTS-1, -4, and -5 in the trabecular meshwork.

Keller KE, Bradley JM, Acott TS.

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5769-77. doi: 10.1167/iovs.09-3673. Epub 2009 Jun 24.


Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases.

Lee SY, Lee HS, Gil M, Kim CJ, Lee YH, Kim KR, Park CS.

Arch Pathol Lab Med. 2014 May;138(5):643-50. doi: 10.5858/arpa.2012-0227-OA.


Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina.

Lee CW, Hwang I, Park CS, Lee H, Park DW, Kang SJ, Lee SH, Kim YH, Park SW, Park SJ.

J Clin Pathol. 2011 May;64(5):399-404. doi: 10.1136/jcp.2010.088484. Epub 2011 Feb 23.


Expression and cellular localization of the CC chemokines PARC and ELC in human atherosclerotic plaques.

Reape TJ, Rayner K, Manning CD, Gee AN, Barnette MS, Burnand KG, Groot PH.

Am J Pathol. 1999 Feb;154(2):365-74.


Cell-specific and developmental expression of lectican-cleaving proteases in mouse hippocampus and neocortex.

Levy C, Brooks JM, Chen J, Su J, Fox MA.

J Comp Neurol. 2015 Mar 1;523(4):629-48. doi: 10.1002/cne.23701. Epub 2014 Nov 21.


The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican.

Cross NA, Chandrasekharan S, Jokonya N, Fowles A, Hamdy FC, Buttle DJ, Eaton CL.

Prostate. 2005 May 15;63(3):269-75.


Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V.

Colige A, Ruggiero F, Vandenberghe I, Dubail J, Kesteloot F, Van Beeumen J, Beschin A, Brys L, Lapière CM, Nusgens B.

J Biol Chem. 2005 Oct 14;280(41):34397-408. Epub 2005 Jul 26.


Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid.

Worley JR, Baugh MD, Hughes DA, Edwards DR, Hogan A, Sampson MJ, Gavrilovic J.

J Biol Chem. 2003 Dec 19;278(51):51340-6. Epub 2003 Oct 8.

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