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IL-18, but not IL-12, is required for optimal cytokine production by influenza virus-specific CD8+ T cells.

Denton AE, Doherty PC, Turner SJ, La Gruta NL.

Eur J Immunol. 2007 Feb;37(2):368-75.


IL-21 and IL-15 cytokine DNA augments HSV specific effector and memory CD8+ T cell response.

Rodrigues L, Nandakumar S, Bonorino C, Rouse BT, Kumaraguru U.

Mol Immunol. 2009 Apr;46(7):1494-504. doi: 10.1016/j.molimm.2008.12.033. Epub 2009 Feb 23.


Establishment and recall of CD8+ T-cell memory in a model of localized transient infection.

Kedzierska K, La Gruta NL, Turner SJ, Doherty PC.

Immunol Rev. 2006 Jun;211:133-45. Review.


IL-12p40 and IL-18 play pivotal roles in orchestrating the cell-mediated immune response to a poxvirus infection.

Wang Y, Chaudhri G, Jackson RJ, Karupiah G.

J Immunol. 2009 Sep 1;183(5):3324-31. doi: 10.4049/jimmunol.0803985. Epub 2009 Aug 5.


TLR2 engagement on memory CD8(+) T cells improves their cytokine-mediated proliferation and IFN-gamma secretion in the absence of Ag.

Cottalorda A, Mercier BC, Mbitikon-Kobo FM, Arpin C, Teoh DY, McMichael A, Marvel J, Bonnefoy-BĂ©rard N.

Eur J Immunol. 2009 Oct;39(10):2673-81. doi: 10.1002/eji.200939627.


IL-15 is critical for the maintenance and innate functions of self-specific CD8(+) T cells.

Itsumi M, Yoshikai Y, Yamada H.

Eur J Immunol. 2009 Jul;39(7):1784-93. doi: 10.1002/eji.200839106.


Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections.

Bachmann MF, Wolint P, Walton S, Schwarz K, Oxenius A.

Eur J Immunol. 2007 Jun;37(6):1502-12.


Contribution of CD8+ T cells to innate immunity: IFN-gamma secretion induced by IL-12 and IL-18.

Berg RE, Cordes CJ, Forman J.

Eur J Immunol. 2002 Oct;32(10):2807-16.


Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes.

Kim S, Shen T, Min B.

J Immunol. 2009 Sep 1;183(5):3033-9. doi: 10.4049/jimmunol.0900332. Epub 2009 Aug 10.


The CD8 T cell response to vaccinia virus exhibits site-dependent heterogeneity of functional responses.

Xiao Z, Curtsinger JM, Prlic M, Jameson SC, Mescher MF.

Int Immunol. 2007 Jun;19(6):733-43. Epub 2007 Jun 1.


Gamma interferon-independent effects of interleukin-12 on immunity to Salmonella enterica serovar Typhimurium.

Price JD, Simpfendorfer KR, Mantena RR, Holden J, Heath WR, van Rooijen N, Strugnell RA, Wijburg OL.

Infect Immun. 2007 Dec;75(12):5753-62. Epub 2007 Sep 17.


Antigen-primed splenic CD8+ T cells impede the development of oral antigen-induced allergic diarrhea.

Yamada A, Ohshima Y, Yasutomi M, Ogura K, Tokuriki S, Naiki H, Mayumi M.

J Allergy Clin Immunol. 2009 Apr;123(4):889-94. doi: 10.1016/j.jaci.2008.12.1115. Epub 2009 Feb 6.


Gamma interferon regulates contraction of the influenza virus-specific CD8 T cell response and limits the size of the memory population.

Prabhu N, Ho AW, Wong KH, Hutchinson PE, Chua YL, Kandasamy M, Lee DC, Sivasankar B, Kemeny DM.

J Virol. 2013 Dec;87(23):12510-22. doi: 10.1128/JVI.01776-13. Epub 2013 Sep 11.


IL-4Ralpha signaling is important for CD8+ T cell cytotoxicity in the absence of CD4+ T cell help.

Marsland BJ, Schmitz N, Kopf M.

Eur J Immunol. 2005 May;35(5):1391-8.


Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus.

Van Der Sluijs KF, Van Elden LJ, Arens R, Nijhuis M, Schuurman R, Florquin S, Kwakkel J, Akira S, Jansen HM, Lutter R, Van Der Polls T.

Immunology. 2005 Jan;114(1):112-20.


Endogenous IL-21 restricts CD8+ T cell expansion and is not required for tumor immunity.

Søndergaard H, Coquet JM, Uldrich AP, McLaughlin N, Godfrey DI, Sivakumar PV, Skak K, Smyth MJ.

J Immunol. 2009 Dec 1;183(11):7326-36. doi: 10.4049/jimmunol.0902697. Epub 2009 Nov 13.


Defective clearance of adenovirus in IRF-1 mice associated with defects in NK and T cells but not macrophages.

Xu X, Zhang HG, Liu ZY, Wu Q, Yang PA, Sun SH, Chen J, Hsu HC, Mountz JD.

Scand J Immunol. 2004 Jul-Aug;60(1-2):89-99.

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