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Items: 1 to 20 of 124

1.

The N-terminus of PKR is responsible for the activation of the NF-kappaB signaling pathway by interacting with the IKK complex.

Bonnet MC, Daurat C, Ottone C, Meurs EF.

Cell Signal. 2006 Nov;18(11):1865-75. Epub 2006 Feb 28.

PMID:
16600570
2.

Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.

Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.

Oncogene. 2007 Feb 22;26(8):1201-12. Epub 2006 Aug 21.

PMID:
16924232
4.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
5.

The double-stranded RNA-activated protein kinase mediates radiation resistance in mouse embryo fibroblasts through nuclear factor kappaB and Akt activation.

von Holzen U, Pataer A, Raju U, Bocangel D, Vorburger SA, Liu Y, Lu X, Roth JA, Aggarwal BB, Barber GN, Keyomarsi K, Hunt KK, Swisher SG.

Clin Cancer Res. 2007 Oct 15;13(20):6032-9.

6.

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

Bonnet MC, Weil R, Dam E, Hovanessian AG, Meurs EF.

Mol Cell Biol. 2000 Jul;20(13):4532-42.

7.

The dsRNA protein kinase PKR: virus and cell control.

García MA, Meurs EF, Esteban M.

Biochimie. 2007 Jun-Jul;89(6-7):799-811. Epub 2007 Mar 12. Review.

PMID:
17451862
8.

A dominant function of IKK/NF-kappaB signaling in global lipopolysaccharide-induced gene expression.

Carayol N, Chen J, Yang F, Jin T, Jin L, States D, Wang CY.

J Biol Chem. 2006 Oct 13;281(41):31142-51. Epub 2006 Aug 16.

9.
10.

The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR.

Dorin D, Bonnet MC, Bannwarth S, Gatignol A, Meurs EF, Vaquero C.

J Biol Chem. 2003 Feb 14;278(7):4440-8. Epub 2002 Dec 9.

11.

Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells.

Park KA, Byun HS, Won M, Yang KJ, Shin S, Piao L, Kim JM, Yoon WH, Junn E, Park J, Seok JH, Hur GM.

Carcinogenesis. 2007 Jan;28(1):71-80. Epub 2006 Jun 14.

PMID:
16774932
12.
13.

The I{kappa}B kinase {beta}/nuclear factor {kappa}B signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression.

Hikoso S, Yamaguchi O, Nakano Y, Takeda T, Omiya S, Mizote I, Taneike M, Oka T, Tamai T, Oyabu J, Uno Y, Matsumura Y, Nishida K, Suzuki K, Kogo M, Hori M, Otsu K.

Circ Res. 2009 Jul 2;105(1):70-9. doi: 10.1161/CIRCRESAHA.108.193318. Epub 2009 May 28.

PMID:
19478205
14.

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

Gil J, Rullas J, García MA, Alcamí J, Esteban M.

Oncogene. 2001 Jan 18;20(3):385-94.

15.
16.

Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.

Jackson-Bernitsas DG, Ichikawa H, Takada Y, Myers JN, Lin XL, Darnay BG, Chaturvedi MM, Aggarwal BB.

Oncogene. 2007 Mar 1;26(10):1385-97. Epub 2006 Sep 4.

PMID:
16953224
17.

GbetaL regulates TNFalpha-induced NF-kappaB signaling by directly inhibiting the activation of IkappaB kinase.

Kim YL, Kim JE, Shin KJ, Lee S, Ahn C, Chung J, Kim DH, Seong JY, Hwang JI.

Cell Signal. 2008 Nov;20(11):2127-33. doi: 10.1016/j.cellsig.2008.08.001. Epub 2008 Aug 9.

PMID:
18755269
19.

The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.

Golks A, Brenner D, Krammer PH, Lavrik IN.

J Exp Med. 2006 May 15;203(5):1295-305. Epub 2006 May 8.

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