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Items: 1 to 20 of 253

1.

LPS, TLR4 and infectious disease diversity.

Miller SI, Ernst RK, Bader MW.

Nat Rev Microbiol. 2005 Jan;3(1):36-46. Review.

PMID:
15608698
2.

Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2.

da Silva Correia J, Soldau K, Christen U, Tobias PS, Ulevitch RJ.

J Biol Chem. 2001 Jun 15;276(24):21129-35. Epub 2001 Mar 26.

3.
4.

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.

Latz E, Visintin A, Lien E, Fitzgerald KA, Monks BG, Kurt-Jones EA, Golenbock DT, Espevik T.

J Biol Chem. 2002 Dec 6;277(49):47834-43. Epub 2002 Sep 24.

5.

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.

Visintin A, Latz E, Monks BG, Espevik T, Golenbock DT.

J Biol Chem. 2003 Nov 28;278(48):48313-20. Epub 2003 Sep 5.

6.

Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2.

Miyake K.

Trends Microbiol. 2004 Apr;12(4):186-92. Review.

PMID:
15051069
7.

A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4.

Kennedy MN, Mullen GE, Leifer CA, Lee C, Mazzoni A, Dileepan KN, Segal DM.

J Biol Chem. 2004 Aug 13;279(33):34698-704. Epub 2004 Jun 1.

8.

Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling.

Saitoh S, Akashi S, Yamada T, Tanimura N, Matsumoto F, Fukase K, Kusumoto S, Kosugi A, Miyake K.

J Endotoxin Res. 2004;10(4):257-60.

PMID:
15373971
9.

MD-2 binds to bacterial lipopolysaccharide.

Viriyakosol S, Kirkland T, Soldau K, Tobias P.

J Endotoxin Res. 2000;6(6):489-91.

PMID:
11521076
10.
11.

Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex.

Fujihara M, Muroi M, Tanamoto K, Suzuki T, Azuma H, Ikeda H.

Pharmacol Ther. 2003 Nov;100(2):171-94. Review.

PMID:
14609719
12.

[The role of myeloid differential protein-2 in innate immunity].

Xu FL, Li L.

Sheng Li Ke Xue Jin Zhan. 2004 Apr;35(2):139-42. Review. Chinese.

PMID:
15285420
13.

CD40-mediated up-regulation of Toll-like receptor 4-MD2 complex on the surface of murine dendritic cells.

Frleta D, Noelle RJ, Wade WF.

J Leukoc Biol. 2003 Dec;74(6):1064-73. Epub 2003 Sep 2.

PMID:
12960264
14.

The amino-terminal region of toll-like receptor 4 is essential for binding to MD-2 and receptor translocation to the cell surface.

Fujimoto T, Yamazaki S, Eto-Kimura A, Takeshige K, Muta T.

J Biol Chem. 2004 Nov 12;279(46):47431-7. Epub 2004 Aug 26.

15.

MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor.

da Silva Correia J, Ulevitch RJ.

J Biol Chem. 2002 Jan 18;277(3):1845-54. Epub 2001 Nov 12.

16.

[Congenital components of immunity: Toll-like receptors in the normal state and in immunopathology].

Koval'chuk LV, Khoreva MV, Varivoda AS.

Zh Mikrobiol Epidemiol Immunobiol. 2005 Jul-Aug;(4):96-104. Review. Russian.

PMID:
16146239
17.

The Toll-like receptor 4 region Glu24-Pro34 is critical for interaction with MD-2.

Nishitani C, Mitsuzawa H, Hyakushima N, Sano H, Matsushima N, Kuroki Y.

Biochem Biophys Res Commun. 2005 Mar 11;328(2):586-90.

PMID:
15694388
18.

Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses.

Triantafilou M, Brandenburg K, Kusumoto S, Fukase K, Mackie A, Seydel U, Triantafilou K.

Biochem J. 2004 Jul 15;381(Pt 2):527-36.

19.

Activation of human meningeal cells is modulated by lipopolysaccharide (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling.

Humphries HE, Triantafilou M, Makepeace BL, Heckels JE, Triantafilou K, Christodoulides M.

Cell Microbiol. 2005 Mar;7(3):415-30.

PMID:
15679844
20.

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