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Items: 1 to 20 of 144

1.
3.

Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.

Grosso S, Pesce E, Brina D, Beugnet A, Loreni F, Biffo S.

PLoS One. 2011;6(12):e29136. doi: 10.1371/journal.pone.0029136. Epub 2011 Dec 22.

4.

The effect of p-4E-BP1 and p-eIF4E on cell proliferation in a breast cancer model.

Pons B, Peg V, Vázquez-Sánchez MA, López-Vicente L, Argelaguet E, Coch L, Martínez A, Hernández-Losa J, Armengol G, Ramon Y Cajal S.

Int J Oncol. 2011 Nov;39(5):1337-45. doi: 10.3892/ijo.2011.1118. Epub 2011 Jul 8.

PMID:
21750861
5.

Regulation of protein synthesis by IGF-I in proximal tubular epithelial cells.

Senthil D, Choudhury GG, Abboud HE, Sonenberg N, Kasinath BS.

Am J Physiol Renal Physiol. 2002 Dec;283(6):F1226-36. Epub 2002 Aug 13.

6.

Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.

Vary TC, Lynch CJ.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E631-42. Epub 2005 Nov 1.

7.

Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.

Wang X, Yue P, Chan CB, Ye K, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Fu H, Khuri FR, Sun SY.

Mol Cell Biol. 2007 Nov;27(21):7405-13. Epub 2007 Aug 27.

8.

Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.

George A, Panda S, Kudmulwar D, Chhatbar SP, Nayak SC, Krishnan HH.

J Biol Chem. 2012 Feb 10;287(7):5042-58. doi: 10.1074/jbc.M111.308916. Epub 2011 Dec 19.

9.

Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis.

Dumstorf CA, Konicek BW, McNulty AM, Parsons SH, Furic L, Sonenberg N, Graff JR.

Mol Cancer Ther. 2010 Dec;9(12):3158-63. doi: 10.1158/1535-7163.MCT-10-0413. Epub 2010 Oct 22.

10.

Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state.

Ptushkina M, von der Haar T, Karim MM, Hughes JM, McCarthy JE.

EMBO J. 1999 Jul 15;18(14):4068-75.

11.

Seasonal and state-dependent changes of eIF4E and 4E-BP1 during mammalian hibernation: implications for the control of translation during torpor.

van Breukelen F, Sonenberg N, Martin SL.

Am J Physiol Regul Integr Comp Physiol. 2004 Aug;287(2):R349-53. Epub 2004 Apr 1.

12.

TGFβ-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy.

Das F, Ghosh-Choudhury N, Bera A, Kasinath BS, Choudhury GG.

J Cell Physiol. 2013 Jul;228(7):1617-26. doi: 10.1002/jcp.24327.

13.

RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.

Villalonga P, Fernández de Mattos S, Ridley AJ.

J Biol Chem. 2009 Dec 18;284(51):35287-96. doi: 10.1074/jbc.M109.050120.

14.

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.

Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, Hoekstra MF, Aebersold R, Sonenberg N.

Genes Dev. 1999 Jun 1;13(11):1422-37.

15.
16.

Shiga toxins activate translational regulation pathways in intestinal epithelial cells.

Colpoys WE, Cochran BH, Carducci TM, Thorpe CM.

Cell Signal. 2005 Jul;17(7):891-9. Epub 2004 Dec 24.

PMID:
15763431
17.

New hierarchical phosphorylation pathway of the translational repressor eIF4E-binding protein 1 (4E-BP1) in ischemia-reperfusion stress.

Ayuso MI, Hernández-Jiménez M, Martín ME, Salinas M, Alcázar A.

J Biol Chem. 2010 Nov 5;285(45):34355-63. doi: 10.1074/jbc.M110.135103. Epub 2010 Aug 24.

18.

Novel translational control in Arc-dependent long term potentiation consolidation in vivo.

Panja D, Dagyte G, Bidinosti M, Wibrand K, Kristiansen AM, Sonenberg N, Bramham CR.

J Biol Chem. 2009 Nov 13;284(46):31498-511. doi: 10.1074/jbc.M109.056077. Epub 2009 Sep 15.

19.

IGF-I and insulin regulate eIF4F formation by different mechanisms in muscle and liver in the ovine fetus.

Shen W, Mallon D, Boyle DW, Liechty EA.

Am J Physiol Endocrinol Metab. 2002 Sep;283(3):E593-603.

20.

Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.

Konicek BW, Stephens JR, McNulty AM, Robichaud N, Peery RB, Dumstorf CA, Dowless MS, Iversen PW, Parsons S, Ellis KE, McCann DJ, Pelletier J, Furic L, Yingling JM, Stancato LF, Sonenberg N, Graff JR.

Cancer Res. 2011 Mar 1;71(5):1849-57. doi: 10.1158/0008-5472.CAN-10-3298. Epub 2011 Jan 13.

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