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Items: 1 to 20 of 119

1.

Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model.

Wong M, Ess KC, Uhlmann EJ, Jansen LA, Li W, Crino PB, Mennerick S, Yamada KA, Gutmann DH.

Ann Neurol. 2003 Aug;54(2):251-6.

PMID:
12891680
2.

Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes.

Jansen LA, Uhlmann EJ, Crino PB, Gutmann DH, Wong M.

Epilepsia. 2005 Dec;46(12):1871-80.

3.

Expression profiling in tuberous sclerosis complex (TSC) knockout mouse astrocytes to characterize human TSC brain pathology.

Ess KC, Uhlmann EJ, Li W, Li H, Declue JE, Crino PB, Gutmann DH.

Glia. 2004 Apr 1;46(1):28-40.

PMID:
14999811
4.

Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex.

Zeng LH, Bero AW, Zhang B, Holtzman DM, Wong M.

Neurobiol Dis. 2010 Mar;37(3):764-71. doi: 10.1016/j.nbd.2009.12.020. Epub 2010 Jan 4.

5.

Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells.

Uhlmann EJ, Apicelli AJ, Baldwin RL, Burke SP, Bajenaru ML, Onda H, Kwiatkowski D, Gutmann DH.

Oncogene. 2002 Jun 6;21(25):4050-9.

6.

Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1.

Wang Y, Greenwood JS, Calcagnotto ME, Kirsch HE, Barbaro NM, Baraban SC.

Ann Neurol. 2007 Feb;61(2):139-52.

PMID:
17279540
7.

Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.

Zeng LH, Rensing NR, Zhang B, Gutmann DH, Gambello MJ, Wong M.

Hum Mol Genet. 2011 Feb 1;20(3):445-54. doi: 10.1093/hmg/ddq491. Epub 2010 Nov 9.

8.

Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures.

Uhlmann EJ, Wong M, Baldwin RL, Bajenaru ML, Onda H, Kwiatkowski DJ, Yamada K, Gutmann DH.

Ann Neurol. 2002 Sep;52(3):285-96.

PMID:
12205640
9.

Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex.

Zeng LH, Ouyang Y, Gazit V, Cirrito JR, Jansen LA, Ess KC, Yamada KA, Wozniak DF, Holtzman DM, Gutmann DH, Wong M.

Neurobiol Dis. 2007 Nov;28(2):184-96. Epub 2007 Jul 21.

10.

Tuberous sclerosis: a primary pathology of astrocytes?

Sosunov AA, Wu X, Weiner HL, Mikell CB, Goodman RR, Crino PD, McKhann GM 2nd.

Epilepsia. 2008;49 Suppl 2:53-62. doi: 10.1111/j.1528-1167.2008.01493.x.

11.

Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation.

Uhlmann EJ, Li W, Scheidenhelm DK, Gau CL, Tamanoi F, Gutmann DH.

Glia. 2004 Aug 1;47(2):180-8.

PMID:
15185396
12.

Tuberous sclerosis and epilepsy: role of astrocytes.

Wong M, Crino PB.

Glia. 2012 Aug;60(8):1244-50. doi: 10.1002/glia.22326. Epub 2012 Mar 21. Review.

PMID:
22438024
13.

Microglial activation during epileptogenesis in a mouse model of tuberous sclerosis complex.

Zhang B, Zou J, Han L, Rensing N, Wong M.

Epilepsia. 2016 Aug;57(8):1317-25. doi: 10.1111/epi.13429. Epub 2016 Jun 6.

14.

Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.

Zou J, Zhang B, Gutmann DH, Wong M.

Epilepsia. 2017 Dec;58(12):2053-2063. doi: 10.1111/epi.13923. Epub 2017 Oct 12.

PMID:
29023667
15.

Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex.

Zhang B, Zou J, Rensing NR, Yang M, Wong M.

Neurobiol Dis. 2015 Aug;80:70-9. doi: 10.1016/j.nbd.2015.04.016. Epub 2015 May 21.

16.

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.

Zeng LH, Xu L, Gutmann DH, Wong M.

Ann Neurol. 2008 Apr;63(4):444-53. doi: 10.1002/ana.21331.

17.

The natural history and treatment of epilepsy in a murine model of tuberous sclerosis.

Erbayat-Altay E, Zeng LH, Xu L, Gutmann DH, Wong M.

Epilepsia. 2007 Aug;48(8):1470-6. Epub 2007 May 1.

18.

Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex.

Boer K, Troost D, Timmermans W, Gorter JA, Spliet WG, Nellist M, Jansen F, Aronica E.

Neuroscience. 2008 Sep 22;156(1):203-15. doi: 10.1016/j.neuroscience.2008.06.073. Epub 2008 Jul 25.

PMID:
18706978
19.

Astroglial plasticity and glutamate function in a chronic mouse model of Parkinson's disease.

Dervan AG, Meshul CK, Beales M, McBean GJ, Moore C, Totterdell S, Snyder AK, Meredith GE.

Exp Neurol. 2004 Nov;190(1):145-56.

PMID:
15473988
20.

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