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Items: 1 to 20 of 97


Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1.

Farassati F, Yang AD, Lee PW.

Nat Cell Biol. 2001 Aug;3(8):745-50.


Oncolysis of pancreatic tumour cells by a gamma34.5-deleted HSV-1 does not rely upon Ras-activation, but on the PI 3-kinase pathway.

Sarinella F, Calistri A, Sette P, Pal├╣ G, Parolin C.

Gene Ther. 2006 Jul;13(14):1080-7. Epub 2006 Mar 23.


Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.

Smith KD, Mezhir JJ, Bickenbach K, Veerapong J, Charron J, Posner MC, Roizman B, Weichselbaum RR.

J Virol. 2006 Feb;80(3):1110-20.


Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras.

Brassard DL, English JM, Malkowski M, Kirschmeier P, Nagabhushan TL, Bishop WR.

Exp Cell Res. 2002 Feb 15;273(2):138-46.


Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes.

Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A.

Am J Pathol. 2008 Dec;173(6):1861-72. doi: 10.2353/ajpath.2008.080376. Epub 2008 Nov 6.


Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis.

Taddeo B, Luo TR, Zhang W, Roizman B.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12408-13. Epub 2003 Oct 6.


Downstream effectors of oncogenic ras in multiple myeloma cells.

Hu L, Shi Y, Hsu JH, Gera J, Van Ness B, Lichtenstein A.

Blood. 2003 Apr 15;101(8):3126-35. Epub 2002 Dec 19.


The Herpes Simplex Virus Virion Host Shutoff Protein Enhances Translation of Viral True Late mRNAs Independently of Suppressing Protein Kinase R and Stress Granule Formation.

Dauber B, Poon D, Dos Santos T, Duguay BA, Mehta N, Saffran HA, Smiley JR.

J Virol. 2016 Jun 10;90(13):6049-6057. doi: 10.1128/JVI.03180-15. Print 2016 Jul 1.


The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus.

Strong JE, Coffey MC, Tang D, Sabinin P, Lee PW.

EMBO J. 1998 Jun 15;17(12):3351-62.


Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication.

Su A, Wang H, Li Y, Wang X, Chen D, Wu Z.

Viruses. 2017 Aug 23;9(9). pii: E235. doi: 10.3390/v9090235.


Roles of Us8A and Its Phosphorylation Mediated by Us3 in Herpes Simplex Virus 1 Pathogenesis.

Kato A, Ando T, Oda S, Watanabe M, Koyanagi N, Arii J, Kawaguchi Y.

J Virol. 2016 May 27;90(12):5622-5635. doi: 10.1128/JVI.00446-16. Print 2016 Jun 15.


Contribution of Ras GTPase/MAP kinase and cytochrome P450 metabolites to deoxycorticosterone-salt-induced hypertension.

Muthalif MM, Benter IF, Khandekar Z, Gaber L, Estes A, Malik S, Parmentier JH, Manne V, Malik KU.

Hypertension. 2000 Jan;35(1 Pt 2):457-63.


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