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Items: 1 to 20 of 110

1.

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection.

Collazo CM, Yap GS, Sempowski GD, Lusby KC, Tessarollo L, Vande Woude GF, Sher A, Taylor GA.

J Exp Med. 2001 Jul 16;194(2):181-8.

2.

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP.

Taylor GA, Collazo CM, Yap GS, Nguyen K, Gregorio TA, Taylor LS, Eagleson B, Secrest L, Southon EA, Reid SW, Tessarollo L, Bray M, McVicar DW, Komschlies KL, Young HA, Biron CA, Sher A, Vande Woude GF.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):751-5.

3.

The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.

Liesenfeld O, Parvanova I, Zerrahn J, Han SJ, Heinrich F, Muñoz M, Kaiser F, Aebischer T, Buch T, Waisman A, Reichmann G, Utermöhlen O, von Stebut E, von Loewenich FD, Bogdan C, Specht S, Saeftel M, Hoerauf A, Mota MM, Könen-Waisman S, Kaufmann SH, Howard JC.

PLoS One. 2011;6(6):e20568. doi: 10.1371/journal.pone.0020568. Epub 2011 Jun 17.

4.

Toxoplasma gondii profilin promotes recruitment of Ly6Chi CCR2+ inflammatory monocytes that can confer resistance to bacterial infection.

Neal LM, Knoll LJ.

PLoS Pathog. 2014 Jun 12;10(6):e1004203. doi: 10.1371/journal.ppat.1004203. eCollection 2014 Jun.

5.

Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.

Feng CG, Collazo-Custodio CM, Eckhaus M, Hieny S, Belkaid Y, Elkins K, Jankovic D, Taylor GA, Sher A.

J Immunol. 2004 Jan 15;172(2):1163-8.

7.

p47 GTPases regulate Toxoplasma gondii survival in activated macrophages.

Butcher BA, Greene RI, Henry SC, Annecharico KL, Weinberg JB, Denkers EY, Sher A, Taylor GA.

Infect Immun. 2005 Jun;73(6):3278-86.

8.

A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.

Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J, Sasai M, Kayama H, Okamoto T, Huang DC, Soldati-Favre D, Horie K, Takeda J, Takeda K.

Immunity. 2012 Aug 24;37(2):302-13. Epub 2012 Jul 12.

10.

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

Degrandi D, Konermann C, Beuter-Gunia C, Kresse A, Würthner J, Kurig S, Beer S, Pfeffer K.

J Immunol. 2007 Dec 1;179(11):7729-40.

11.

RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4581-90. doi: 10.1073/pnas.1510031112. Epub 2015 Aug 3.

12.

Balance of Irgm protein activities determines IFN-gamma-induced host defense.

Henry SC, Daniell XG, Burroughs AR, Indaram M, Howell DN, Coers J, Starnbach MN, Hunn JP, Howard JC, Feng CG, Sher A, Taylor GA.

J Leukoc Biol. 2009 May;85(5):877-85. doi: 10.1189/jlb.1008599. Epub 2009 Jan 27.

13.

The proinflammatory cytokine-induced IRG1 protein associates with mitochondria.

Degrandi D, Hoffmann R, Beuter-Gunia C, Pfeffer K.

J Interferon Cytokine Res. 2009 Jan;29(1):55-67. doi: 10.1089/jir.2008.0013. Erratum in: J Interferon Cytokine Res. 2009 Sep;29(9):643.

PMID:
19014335
16.

Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review.

Zhao YO, Rohde C, Lilue JT, Könen-Waisman S, Khaminets A, Hunn JP, Howard JC.

Mem Inst Oswaldo Cruz. 2009 Mar;104(2):234-40. Review.

17.

Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

Degrandi D, Kravets E, Konermann C, Beuter-Gunia C, Klümpers V, Lahme S, Wischmann E, Mausberg AK, Beer-Hammer S, Pfeffer K.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):294-9. doi: 10.1073/pnas.1205635110. Epub 2012 Dec 17.

18.
19.

Identification of a role for NF-kappa B2 in the regulation of apoptosis and in maintenance of T cell-mediated immunity to Toxoplasma gondii.

Caamaño J, Tato C, Cai G, Villegas EN, Speirs K, Craig L, Alexander J, Hunter CA.

J Immunol. 2000 Nov 15;165(10):5720-8.

20.

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