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Items: 1 to 20 of 173

1.

Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis.

Richard SB, Bowman ME, Kwiatkowski W, Kang I, Chow C, Lillo AM, Cane DE, Noel JP.

Nat Struct Biol. 2001 Jul;8(7):641-8.

PMID:
11427897
2.

Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol.

Rohdich F, Wungsintaweekul J, Fellermeier M, Sagner S, Herz S, Kis K, Eisenreich W, Bacher A, Zenk MH.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11758-63.

3.

Crystal structure of 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis.

Wada T, Kuzuyama T, Satoh S, Kuramitsu S, Yokoyama S, Unzai S, Tame JR, Park SY.

J Biol Chem. 2003 Aug 8;278(32):30022-7. Epub 2003 May 27.

4.

Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids.

Steinbacher S, Kaiser J, Wungsintaweekul J, Hecht S, Eisenreich W, Gerhardt S, Bacher A, Rohdich F.

J Mol Biol. 2002 Feb 8;316(1):79-88.

PMID:
11829504
5.
6.

LytB, a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli.

Altincicek B, Kollas A, Eberl M, Wiesner J, Sanderbrand S, Hintz M, Beck E, Jomaa H.

FEBS Lett. 2001 Jun 15;499(1-2):37-40.

7.

Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway.

Richard SB, Ferrer JL, Bowman ME, Lillo AM, Tetzlaff CN, Cane DE, Noel JP.

J Biol Chem. 2002 Mar 8;277(10):8667-72. Epub 2002 Jan 10.

8.

Crystallization and preliminary X-ray diffraction studies of recombinant Escherichia coli 4-diphosphocytidyl-2-C-methyl-D-erythritol synthetase.

Kemp LE, Bond CS, Hunter WN.

Acta Crystallogr D Biol Crystallogr. 2001 Aug;57(Pt 8):1189-91. Epub 2001 Jul 23.

PMID:
11468415
10.
11.

Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway.

Wanke M, Skorupinska-Tudek K, Swiezewska E.

Acta Biochim Pol. 2001;48(3):663-72. Review.

12.

Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis.

Kishida H, Wada T, Unzai S, Kuzuyama T, Takagi M, Terada T, Shirouzu M, Yokoyama S, Tame JR, Park SY.

Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):23-31. Epub 2002 Dec 19.

PMID:
12499535
13.

Kinetic analysis of Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase, wild type and mutants, reveals roles of active site amino acids.

Richard SB, Lillo AM, Tetzlaff CN, Bowman ME, Noel JP, Cane DE.

Biochemistry. 2004 Sep 28;43(38):12189-97.

PMID:
15379557
14.

Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development.

Eoh H, Brown AC, Buetow L, Hunter WN, Parish T, Kaur D, Brennan PJ, Crick DC.

J Bacteriol. 2007 Dec;189(24):8922-7. Epub 2007 Oct 5.

15.

Homology modeling of Mycobacterium tuberculosis 2C-methyl-D-erythritol-4-phosphate cytidylyltransferase, the third enzyme in the MEP pathway for isoprenoid biosynthesis.

Obiol-Pardo C, Cordero A, Rubio-Martinez J, Imperial S.

J Mol Model. 2010 Jun;16(6):1061-73. doi: 10.1007/s00894-009-0615-x. Epub 2009 Nov 15.

PMID:
19916033
16.
17.

Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme.

Bertrand T, Briozzo P, Assairi L, Ofiteru A, Bucurenci N, Munier-Lehmann H, Golinelli-Pimpaneau B, Bârzu O, Gilles AM.

J Mol Biol. 2002 Feb 1;315(5):1099-110.

PMID:
11827479
18.

Crystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.

Reuter K, Sanderbrand S, Jomaa H, Wiesner J, Steinbrecher I, Beck E, Hintz M, Klebe G, Stubbs MT.

J Biol Chem. 2002 Feb 15;277(7):5378-84. Epub 2001 Dec 7.

19.

Structure and reactivity in the non-mevalonate pathway of isoprenoid biosynthesis.

Hunter WN, Bond CS, Gabrielsen M, Kemp LE.

Biochem Soc Trans. 2003 Jun;31(Pt 3):537-42. Review.

PMID:
12773152

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