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Items: 1 to 200 of 736

1.

Association of In Utero Persistent Organic Pollutant Exposure with Placental Thyroid Hormones.

Li ZM, Hernandez-Moreno D, Main KM, Skakkebæk NE, Kiviranta H, Toppari J, Feldt-Rasmussen U, Shen H, Schramm KW, De Angelis M.

Endocrinology. 2018 Jul 27. doi: 10.1210/en.2018-00542. [Epub ahead of print]

PMID:
30059991
2.

Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors.

Tarsitano MG, Bandak M, Jørgensen N, Skakkebaek NE, Juul A, Lenzi A, Daugaard G, Rajpert-De Meyts E.

Andrology. 2018 Jul 6. doi: 10.1111/andr.12508. [Epub ahead of print]

PMID:
29981219
3.

The Possible Impact of Antenatal Exposure to Ubiquitous Phthalates Upon Male Reproductive Function at 20 Years of Age.

Hart RJ, Frederiksen H, Doherty DA, Keelan JA, Skakkebaek NE, Minaee NS, McLachlan R, Newnham JP, Dickinson JE, Pennell CE, Norman RJ, Main KM.

Front Endocrinol (Lausanne). 2018 Jun 4;9:288. doi: 10.3389/fendo.2018.00288. eCollection 2018.

4.

Parental occupational exposure to solvents and heavy metals and risk of developing testicular germ cell tumors in sons (NORD-TEST Denmark).

Olsson A, Togawa K, Schüz J, Le Cornet C, Fervers B, Oksbjerg Dalton S, Pukkala E, Feychting M, Skakkebæk NE, Hansen J.

Scand J Work Environ Health. 2018 Jun 7. pii: 3732. doi: 10.5271/sjweh.3732. [Epub ahead of print]

5.

Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells.

Winge SB, Dalgaard MD, Belling KG, Jensen JM, Nielsen JE, Aksglaede L, Schierup MH, Brunak S, Skakkebæk NE, Juul A, Rajpert-De Meyts E, Almstrup K.

Cell Death Dis. 2018 May 22;9(6):586. doi: 10.1038/s41419-018-0671-1.

6.

Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years.

Priskorn L, Nordkap L, Bang AK, Krause M, Holmboe SA, Egeberg Palme DL, Winge SB, Mørup N, Carlsen E, Joensen UN, Blomberg Jensen M, Main KM, Juul A, Skakkebaek NE, Jensen TK, Jørgensen N.

Hum Reprod. 2018 Jun 1;33(6):998-1008. doi: 10.1093/humrep/dey090.

PMID:
29659832
7.

Postnatal Changes in Testicular Position Are Associated With IGF-I and Function of Sertoli and Leydig Cells.

Koskenniemi JJ, Virtanen HE, Wohlfahrt-Veje C, Löyttyniemi E, Skakkebaek NE, Juul A, Andersson AM, Main KM, Toppari J.

J Clin Endocrinol Metab. 2018 Apr 1;103(4):1429-1437. doi: 10.1210/jc.2017-01889.

PMID:
29408984
8.

Maternal exposure to UV filters: associations with maternal thyroid hormones, IGF-I/IGFBP3 and birth outcomes.

Krause M, Frederiksen H, Sundberg K, Jørgensen FS, Jensen LN, Nørgaard P, Jørgensen C, Ertberg P, Petersen JH, Feldt-Rasmussen U, Juul A, Drzewiecki KT, Skakkebaek NE, Andersson AM.

Endocr Connect. 2018 Feb;7(2):334-346. doi: 10.1530/EC-17-0375. Epub 2018 Jan 23.

9.

Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry.

Li ZM, Giesert F, Vogt-Weisenhorn D, Main KM, Skakkebæk NE, Kiviranta H, Toppari J, Feldt-Rasmussen U, Shen H, Schramm KW, De Angelis M.

J Chromatogr A. 2018 Jan 26;1534:85-92. doi: 10.1016/j.chroma.2017.12.048. Epub 2017 Dec 24.

PMID:
29307529
10.

Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status.

Egeberg Palme DL, Rehfeld A, Bang AK, Nikolova KA, Kjærulff S, Petersen MR, Jeppesen JV, Glensbjerg M, Juul A, Skakkebæk NE, Ziebe S, Jørgensen N, Almstrup K.

Hum Reprod. 2018 Jan 2. doi: 10.1093/humrep/dex380. [Epub ahead of print]

PMID:
29304248
11.

Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?

Bang AK, Busch AS, Almstrup K, Gromoll J, Kliesch S, Rajpert-De Meyts E, Skakkebaek NE, Juul A, Tüttelmann F, Jørgensen N.

Andrology. 2018 Jan;6(1):176-183. doi: 10.1111/andr.12440. Epub 2017 Nov 27.

PMID:
29179257
12.

Anogenital distance as a phenotypic signature through infancy.

Priskorn L, Petersen JH, Jørgensen N, Kyhl HB, Andersen MS, Main KM, Andersson AM, Skakkebaek NE, Jensen TK.

Pediatr Res. 2018 Mar;83(3):573-579. doi: 10.1038/pr.2017.287. Epub 2017 Dec 20.

PMID:
29155806
13.

Presence of benzophenones commonly used as UV filters and absorbers in paired maternal and fetal samples.

Krause M, Frederiksen H, Sundberg K, Jørgensen FS, Jensen LN, Nørgaard P, Jørgensen C, Ertberg P, Juul A, Drzewiecki KT, Skakkebaek NE, Andersson AM.

Environ Int. 2018 Jan;110:51-60. doi: 10.1016/j.envint.2017.10.005.

PMID:
29100749
14.

Individual testosterone decline and future mortality risk in men.

Holmboe SA, Skakkebæk NE, Juul A, Scheike T, Jensen TK, Linneberg A, Thuesen BH, Andersson AM.

Eur J Endocrinol. 2018 Jan;178(1):123-130. doi: 10.1530/EJE-17-0280. Epub 2017 Oct 24.

PMID:
29066571
15.

Germ Cell Neoplasia in Situ and Preserved Fertility Despite Suppressed Gonadotropins in a Patient With Testotoxicosis.

Juel Mortensen L, Blomberg Jensen M, Christiansen P, Rønholt AM, Jørgensen A, Frederiksen H, Nielsen JE, Loya AC, Grønkær Toft B, Skakkebæk NE, Rajpert-De Meyts E, Juul A.

J Clin Endocrinol Metab. 2017 Dec 1;102(12):4411-4416. doi: 10.1210/jc.2017-01761.

PMID:
29029242
16.

Sperm counts, testicular cancers, and the environment.

Skakkebaek NE.

BMJ. 2017 Oct 10;359:j4517. doi: 10.1136/bmj.j4517. No abstract available.

PMID:
29017996
17.

Possible involvement of the glucocorticoid receptor (NR3C1) and selected NR3C1 gene variants in regulation of human testicular function.

Nordkap L, Almstrup K, Nielsen JE, Bang AK, Priskorn L, Krause M, Holmboe SA, Winge SB, Egeberg Palme DL, Mørup N, Petersen JH, Juul A, Skakkebaek NE, Rajpert-De Meyts E, Jørgensen N.

Andrology. 2017 Nov;5(6):1105-1114. doi: 10.1111/andr.12418. Epub 2017 Oct 9.

PMID:
28992366
18.

A crossover-crossback prospective study of dibutyl-phthalate exposure from mesalamine medications and serum reproductive hormones in men.

Nassan FL, Coull BA, Skakkebaek NE, Andersson AM, Williams MA, Mínguez-Alarcón L, Krawetz SA, Hall JE, Hait EJ, Korzenik JR, Ford JB, Moss AC, Hauser R.

Environ Res. 2018 Jan;160:121-131. doi: 10.1016/j.envres.2017.09.025. Epub 2017 Oct 1.

PMID:
28978458
19.

Parental Occupational Exposure to Organic Solvents and Testicular Germ Cell Tumors in their Offspring: NORD-TEST Study.

Le Cornet C, Fervers B, Pukkala E, Tynes T, Feychting M, Hansen J, Togawa K, Nordby KC, Oksbjerg Dalton S, Uuksulainen S, Wiebert P, Woldbæk T, Skakkebæk NE, Olsson A, Schüz J.

Environ Health Perspect. 2017 Jun 30;125(6):067023. doi: 10.1289/EHP864.

20.

Personal Care Product Use in Men and Urinary Concentrations of Select Phthalate Metabolites and Parabens: Results from the Environment And Reproductive Health (EARTH) Study.

Nassan FL, Coull BA, Gaskins AJ, Williams MA, Skakkebaek NE, Ford JB, Ye X, Calafat AM, Braun JM, Hauser R.

Environ Health Perspect. 2017 Aug 18;125(8):087012. doi: 10.1289/EHP1374.

21.

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner.

Rehfeld A, Egeberg DL, Almstrup K, Petersen JH, Dissing S, Skakkebæk NE.

Endocr Connect. 2018 Jan;7(1):16-25. doi: 10.1530/EC-17-0156. Epub 2017 Sep 5.

22.

Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study.

Mogensen DM, Pihl MB, Skakkebæk NE, Andersen HR, Juul A, Kyhl HB, Swan S, Kristensen DM, Andersen MS, Lind DV, Jensen TK.

Environ Health. 2017 Jun 21;16(1):68. doi: 10.1186/s12940-017-0263-z.

23.

Exposure to phenols, parabens and UV filters: Associations with loss-of-function mutations in the filaggrin gene in men from the general population.

Joensen UN, Jørgensen N, Thyssen JP, Petersen JH, Szecsi PB, Stender S, Andersson AM, Skakkebæk NE, Frederiksen H.

Environ Int. 2017 Aug;105:105-111. doi: 10.1016/j.envint.2017.05.013. Epub 2017 May 17.

PMID:
28525834
24.

Influence of marital status on testosterone levels-A ten year follow-up of 1113 men.

Holmboe SA, Priskorn L, Jørgensen N, Skakkebaek NE, Linneberg A, Juul A, Andersson AM.

Psychoneuroendocrinology. 2017 Jun;80:155-161. doi: 10.1016/j.psyneuen.2017.03.010. Epub 2017 Mar 10.

PMID:
28376340
25.

Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity.

Belling K, Russo F, Jensen AB, Dalgaard MD, Westergaard D, Rajpert-De Meyts E, Skakkebæk NE, Juul A, Brunak S.

Hum Mol Genet. 2017 Apr 1;26(7):1219-1229. doi: 10.1093/hmg/ddx014.

26.

Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window.

van den Driesche S, Kilcoyne KR, Wagner I, Rebourcet D, Boyle A, Mitchell R, McKinnell C, Macpherson S, Donat R, Shukla CJ, Jorgensen A, Meyts ER, Skakkebaek NE, Sharpe RM.

JCI Insight. 2017 Mar 23;2(6):e91204. doi: 10.1172/jci.insight.91204.

27.

Assumed non-persistent environmental chemicals in human adipose tissue; matrix stability and correlation with levels measured in urine and serum.

Artacho-Cordón F, Arrebola JP, Nielsen O, Hernández P, Skakkebaek NE, Fernández MF, Andersson AM, Olea N, Frederiksen H.

Environ Res. 2017 Jul;156:120-127. doi: 10.1016/j.envres.2017.03.030. Epub 2017 Mar 22.

PMID:
28342347
28.

Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents.

Lottrup G, Belling K, Leffers H, Nielsen JE, Dalgaard MD, Juul A, Skakkebæk NE, Brunak S, Rajpert-De Meyts E.

Mol Hum Reprod. 2017 May 1;23(5):339-354. doi: 10.1093/molehr/gax012.

PMID:
28333300
29.

Validation of image cytometry for sperm concentration measurement: Comparison with manual counting of 4010 human semen samples.

Egeberg Palme DL, Johannsen TH, Petersen JH, Skakkebæk NE, Juul A, Jørgensen N, Almstrup K.

Clin Chim Acta. 2017 May;468:114-119. doi: 10.1016/j.cca.2017.02.014. Epub 2017 Feb 27.

PMID:
28242391
30.

Leydig cell clustering and Reinke crystal distribution in relation to hormonal function in adult patients with testicular dysgenesis syndrome (TDS) including cryptorchidism.

Soerensen RR, Johannsen TH, Skakkebaek NE, Rajpert-De Meyts E.

Hormones (Athens). 2016 Oct;15(4):518-526. doi: 10.14310/horm.2002.1708.

31.

Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations.

Kirk IK, Weinhold N, Belling K, Skakkebæk NE, Jensen TS, Leffers H, Juul A, Brunak S.

Cell Syst. 2017 Mar 22;4(3):357-364.e3. doi: 10.1016/j.cels.2017.01.001. Epub 2017 Feb 15.

32.

Is human fecundity changing? A discussion of research and data gaps precluding us from having an answer.

Smarr MM, Sapra KJ, Gemmill A, Kahn LG, Wise LA, Lynch CD, Factor-Litvak P, Mumford SL, Skakkebaek NE, Slama R, Lobdell DT, Stanford JB, Jensen TK, Boyle EH, Eisenberg ML, Turek PJ, Sundaram R, Thoma ME, Buck Louis GM.

Hum Reprod. 2017 Mar 1;32(3):499-504. doi: 10.1093/humrep/dew361. Review.

33.

Exposure to UV filters during summer and winter in Danish kindergarten children.

Krause M, Andersson AM, Skakkebaek NE, Frederiksen H.

Environ Int. 2017 Feb;99:177-184. doi: 10.1016/j.envint.2016.11.011. Epub 2016 Nov 16.

PMID:
27865524
34.

Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother-child pairs.

Lind DV, Main KM, Kyhl HB, Kristensen DM, Toppari J, Andersen HR, Andersen MS, Skakkebæk NE, Jensen TK.

Hum Reprod. 2017 Jan;32(1):223-231. Epub 2016 Nov 16.

PMID:
27852690
35.

Chemical UV Filters Mimic the Effect of Progesterone on Ca2+ Signaling in Human Sperm Cells.

Rehfeld A, Dissing S, Skakkebæk NE.

Endocrinology. 2016 Nov;157(11):4297-4308. Epub 2016 Sep 1.

PMID:
27583790
36.

Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility.

Olesen IA, Andersson AM, Aksglaede L, Skakkebaek NE, Rajpert-de Meyts E, Joergensen N, Juul A.

Fertil Steril. 2017 Jan;107(1):74-82.e7. doi: 10.1016/j.fertnstert.2016.09.015. Epub 2016 Oct 25.

PMID:
27793385
37.

Reply to Eugenio Ventimiglia, Francesco Montorsi, and Andrea Salonia's Letter to the Editor re: Jakob Damsgaard, Ulla N. Joensen, Elisabeth Carlsen, et al. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. Eur Urol 2016;70:1019-29.

Damsgaard J, Joensen UN, Carlsen E, Erenpreiss J, Jensen MB, Matulevicius V, Zilaitiene B, Olesen IA, Perheentupa A, Punab M, Salzbrunn A, Toppari J, Virtanen HE, Juul A, Skakkebæk NE, Jørgensen N.

Eur Urol. 2017 Feb;71(2):e71-e72. doi: 10.1016/j.eururo.2016.09.002. Epub 2016 Sep 13. No abstract available.

PMID:
27638092
38.

UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents.

Frederiksen H, Nielsen O, Skakkebaek NE, Juul A, Andersson AM.

Int J Hyg Environ Health. 2017 Mar;220(2 Pt A):244-253. doi: 10.1016/j.ijheh.2016.08.005. Epub 2016 Sep 1.

PMID:
27637469
39.

A crossover-crossback prospective study of dibutyl-phthalate exposure from mesalamine medications and semen quality in men with inflammatory bowel disease.

Nassan FL, Coull BA, Skakkebaek NE, Williams MA, Dadd R, Mínguez-Alarcón L, Krawetz SA, Hait EJ, Korzenik JR, Moss AC, Ford JB, Hauser R.

Environ Int. 2016 Oct;95:120-30. doi: 10.1016/j.envint.2016.08.006. Epub 2016 Aug 26.

40.

Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women.

Antignac JP, Main KM, Virtanen HE, Boquien CY, Marchand P, Venisseau A, Guiffard I, Bichon E, Wohlfahrt-Veje C, Legrand A, Boscher C, Skakkebæk NE, Toppari J, Le Bizec B.

Environ Pollut. 2016 Nov;218:728-738. doi: 10.1016/j.envpol.2016.07.069. Epub 2016 Aug 9.

PMID:
27521295
41.

Is Sedentary Lifestyle Associated With Testicular Function? A Cross-Sectional Study of 1,210 Men.

Priskorn L, Jensen TK, Bang AK, Nordkap L, Joensen UN, Lassen TH, Olesen IA, Swan SH, Skakkebaek NE, Jørgensen N.

Am J Epidemiol. 2016 Aug 15;184(4):284-94. doi: 10.1093/aje/kwv338. Epub 2016 Aug 8.

PMID:
27501721
42.

Parental Occupational Exposure to Heavy Metals and Welding Fumes and Risk of Testicular Germ Cell Tumors in Offspring: A Registry-Based Case-Control Study.

Togawa K, Le Cornet C, Feychting M, Tynes T, Pukkala E, Hansen J, Olsson A, Oksbjerg Dalton S, Nordby KC, Uuksulainen S, Wiebert P, Woldbæk T, Skakkebæk NE, Fervers B, Schüz J.

Cancer Epidemiol Biomarkers Prev. 2016 Oct;25(10):1426-1434. Epub 2016 Jul 20.

43.

Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries.

Damsgaard J, Joensen UN, Carlsen E, Erenpreiss J, Blomberg Jensen M, Matulevicius V, Zilaitiene B, Olesen IA, Perheentupa A, Punab M, Salzbrunn A, Toppari J, Virtanen HE, Juul A, Skakkebæk NE, Jørgensen N.

Eur Urol. 2016 Dec;70(6):1019-1029. doi: 10.1016/j.eururo.2016.06.044. Epub 2016 Jul 14.

PMID:
27423503
44.

Endocrine disrupters: we need research, biomonitoring and action.

Andersson AM, Bay K, Frederiksen H, Skakkebaek NE.

Andrology. 2016 Jul;4(4):556-60. doi: 10.1111/andr.12244. Epub 2016 Jul 11. No abstract available.

45.

Early Life Events Predict Adult Testicular Function; Data Derived From the Western Australian (Raine) Birth Cohort.

Hart RJ, Doherty DA, Keelan JA, McLachlan R, Skakkebaek NE, Norman RJ, Dickinson JE, Pennell CE, Newnham JP, Hickey M, Handelsman DJ.

J Clin Endocrinol Metab. 2016 Sep;101(9):3333-44. doi: 10.1210/jc.2016-1646. Epub 2016 Jun 24.

PMID:
27340882
46.

Low Testosterone: A Risk Marker Rather Than a Risk Factor for Type 2 Diabetes.

Holmboe SA, Jensen TK, Linneberg A, Scheike T, Thuesen BH, Skakkebaek NE, Juul A, Andersson AM.

J Clin Endocrinol Metab. 2016 Aug;101(8):3180-90. doi: 10.1210/jc.2016-1778. Epub 2016 Jun 10.

PMID:
27285294
47.

Self-reported onset of puberty and subsequent semen quality and reproductive hormones in healthy young men.

Jensen TK, Finne KF, Skakkebæk NE, Andersson AM, Olesen IA, Joensen UN, Bang AK, Nordkap L, Priskorn L, Krause M, Jørgensen N, Juul A.

Hum Reprod. 2016 Aug;31(8):1886-94. doi: 10.1093/humrep/dew122. Epub 2016 Jun 6.

PMID:
27270973
48.

Genetic Variations in FSH Action Affect Sex Hormone Levels and Breast Tissue Size in Infant Girls: A Pilot Study.

Henriksen LS, Hagen CP, Assens M, Busch AS, Skakkebæk NE, Almstrup K, Main KM.

J Clin Endocrinol Metab. 2016 Aug;101(8):3191-8. doi: 10.1210/jc.2016-1672. Epub 2016 Jun 7.

PMID:
27270476
49.

Prenatal pesticide exposure and PON1 genotype associated with adolescent body fat distribution evaluated by dual X-ray absorptiometry (DXA).

Tinggaard J, Wohlfahrt-Veje C, Husby S, Christiansen L, Skakkebaek NE, Jensen TK, Grandjean P, Main KM, Andersen HR.

Andrology. 2016 Jul;4(4):735-44. doi: 10.1111/andr.12194. Epub 2016 May 26.

50.

Polygenic susceptibility to testicular cancer: implications for personalised health care.

Litchfield K, Mitchell JS, Shipley J, Huddart R, Rajpert-De Meyts E, Skakkebæk NE, Houlston RS, Turnbull C.

Br J Cancer. 2016 Jun 14;114(12):e22. doi: 10.1038/bjc.2016.136. Epub 2016 May 26. No abstract available.

51.

Sperm retrieval in adolescent males with Klinefelter syndrome: medical and ethical issues.

Rogol AD, Skakkebaek NE.

Transl Pediatr. 2016 Apr;5(2):104-6. doi: 10.21037/tp.2016.04.05. No abstract available.

52.

Testicular Growth During Puberty in Boys With and Without a History of Congenital Cryptorchidism.

Sadov S, Koskenniemi JJ, Virtanen HE, Perheentupa A, Petersen JH, Skakkebaek NE, Main KM, Toppari J.

J Clin Endocrinol Metab. 2016 Jun;101(6):2570-7. doi: 10.1210/jc.2015-3329. Epub 2016 Apr 6.

PMID:
27049351
53.

Pubertal Onset in Boys and Girls Is Influenced by Pubertal Timing of Both Parents.

Wohlfahrt-Veje C, Mouritsen A, Hagen CP, Tinggaard J, Mieritz MG, Boas M, Petersen JH, Skakkebæk NE, Main KM.

J Clin Endocrinol Metab. 2016 Jul;101(7):2667-74. doi: 10.1210/jc.2016-1073. Epub 2016 Mar 25.

PMID:
27014950
54.

Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis.

Trasande L, Zoeller RT, Hass U, Kortenkamp A, Grandjean P, Myers JP, DiGangi J, Hunt PM, Rudel R, Sathyanarayana S, Bellanger M, Hauser R, Legler J, Skakkebaek NE, Heindel JJ.

Andrology. 2016 Jul;4(4):565-72. doi: 10.1111/andr.12178. Epub 2016 Mar 22.

55.

In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia.

Shannon M, Rehfeld A, Frizzell C, Livingstone C, McGonagle C, Skakkebaek NE, Wielogórska E, Connolly L.

Mol Cell Endocrinol. 2016 May 15;427:65-72. doi: 10.1016/j.mce.2016.03.005. Epub 2016 Mar 8.

PMID:
26965840
56.

Compensated reduction in Leydig cell function is associated with lower semen quality variables: a study of 8182 European young men.

Jørgensen N, Joensen UN, Toppari J, Punab M, Erenpreiss J, Zilaitiene B, Paasch U, Salzbrunn A, Fernandez MF, Virtanen HE, Matulevicius V, Olea N, Jensen TK, Petersen JH, Skakkebæk NE, Andersson AM.

Hum Reprod. 2016 May;31(5):947-57. doi: 10.1093/humrep/dew021. Epub 2016 Mar 2.

PMID:
26936886
57.

Germ cell neoplasia in situ (GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy.

Berney DM, Looijenga LH, Idrees M, Oosterhuis JW, Rajpert-De Meyts E, Ulbright TM, Skakkebaek NE.

Histopathology. 2016 Jul;69(1):7-10. doi: 10.1111/his.12958. Epub 2016 Apr 12. Review.

PMID:
26918959
58.

Prenatal Triclosan Exposure and Anthropometric Measures Including Anogenital Distance in Danish Infants.

Lassen TH, Frederiksen H, Kyhl HB, Swan SH, Main KM, Andersson AM, Lind DV, Husby S, Wohlfahrt-Veje C, Skakkebæk NE, Jensen TK.

Environ Health Perspect. 2016 Aug;124(8):1261-8. doi: 10.1289/ehp.1409637. Epub 2016 Feb 23.

59.
60.

The Path Forward on Endocrine Disruptors Requires Focus on the Basics.

Zoeller RT, Bergman Å, Becher G, Bjerregaard P, Bornman R, Brandt I, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Skakkebaek N, Toppari J, Vandenberg L.

Toxicol Sci. 2016 Feb;149(2):272. doi: 10.1093/toxsci/kfv329. No abstract available.

PMID:
26811417
61.

Semen quality improves marginally during young adulthood: a longitudinal follow-up study.

Perheentupa A, Sadov S, Rönkä R, Virtanen HE, Rodprasert W, Vierula M, Jørgensen N, Skakkebæk NE, Toppari J.

Hum Reprod. 2016 Mar;31(3):502-10. doi: 10.1093/humrep/dev328. Epub 2016 Jan 5.

62.

Prenatal Exposure to Phthalates and Anogenital Distance in Male Infants from a Low-Exposed Danish Cohort (2010-2012).

Jensen TK, Frederiksen H, Kyhl HB, Lassen TH, Swan SH, Bornehag CG, Skakkebaek NE, Main KM, Lind DV, Husby S, Andersson AM.

Environ Health Perspect. 2016 Jul;124(7):1107-13. doi: 10.1289/ehp.1509870. Epub 2015 Dec 15.

63.

Temporal Trends in Fertility Rates: A Nationwide Registry Based Study from 1901 to 2014.

Blomberg Jensen M, Priskorn L, Jensen TK, Juul A, Skakkebaek NE.

PLoS One. 2015 Dec 2;10(12):e0143722. doi: 10.1371/journal.pone.0143722. eCollection 2015.

64.

Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.

Skakkebaek NE, Rajpert-De Meyts E, Buck Louis GM, Toppari J, Andersson AM, Eisenberg ML, Jensen TK, Jørgensen N, Swan SH, Sapra KJ, Ziebe S, Priskorn L, Juul A.

Physiol Rev. 2016 Jan;96(1):55-97. doi: 10.1152/physrev.00017.2015. Review.

65.

The Association of Reproductive Hormone Levels and All-Cause, Cancer, and Cardiovascular Disease Mortality in Men.

Holmboe SA, Vradi E, Jensen TK, Linneberg A, Husemoen LL, Scheike T, Skakkebæk NE, Juul A, Andersson AM.

J Clin Endocrinol Metab. 2015 Dec;100(12):4472-80. doi: 10.1210/jc.2015-2460. Epub 2015 Oct 21.

PMID:
26488309
66.

Psychological stress and testicular function: a cross-sectional study of 1,215 Danish men.

Nordkap L, Jensen TK, Hansen ÅM, Lassen TH, Bang AK, Joensen UN, Blomberg Jensen M, Skakkebæk NE, Jørgensen N.

Fertil Steril. 2016 Jan;105(1):174-87.e1-2. doi: 10.1016/j.fertnstert.2015.09.016. Epub 2015 Oct 23.

PMID:
26477499
67.

Polygenic susceptibility to testicular cancer: implications for personalised health care.

Litchfield K, Mitchell JS, Shipley J, Huddart R, Rajpert-De Meyts E, Skakkebæk NE, Houlston RS, Turnbull C.

Br J Cancer. 2015 Nov 17;113(10):1512-8. doi: 10.1038/bjc.2015.334. Epub 2015 Oct 13. Erratum in: Br J Cancer. 2016 Jun 14;114(12):e22.

68.

Pathogenesis of germ cell neoplasia in testicular dysgenesis and disorders of sex development.

Jørgensen A, Lindhardt Johansen M, Juul A, Skakkebaek NE, Main KM, Rajpert-De Meyts E.

Semin Cell Dev Biol. 2015 Sep;45:124-37. doi: 10.1016/j.semcdb.2015.09.013. Epub 2015 Sep 26. Review.

PMID:
26410164
69.

Testicular function in a birth cohort of young men.

Hart RJ, Doherty DA, McLachlan RI, Walls ML, Keelan JA, Dickinson JE, Skakkebaek NE, Norman RJ, Handelsman DJ.

Hum Reprod. 2015 Dec;30(12):2713-24. doi: 10.1093/humrep/dev244. Epub 2015 Sep 25.

PMID:
26409015
70.

Association between levels of persistent organic pollutants in adipose tissue and cryptorchidism in early childhood: a case-control study.

Koskenniemi JJ, Virtanen HE, Kiviranta H, Damgaard IN, Matomäki J, Thorup JM, Hurme T, Skakkebaek NE, Main KM, Toppari J.

Environ Health. 2015 Sep 24;14:78. doi: 10.1186/s12940-015-0065-0.

71.

Diagnostic markers for germ cell neoplasms: from placental-like alkaline phosphatase to micro-RNAs.

Rajpert-De Meyts E, Nielsen JE, Skakkebaek NE, Almstrup K.

Folia Histochem Cytobiol. 2015;53(3):177-88. doi: 10.5603/FHC.a2015.0020. Epub 2015 Aug 26. Review.

72.

Testicular germ cell tumours and parental occupational exposure to pesticides: a register-based case-control study in the Nordic countries (NORD-TEST study).

Le Cornet C, Fervers B, Dalton SO, Feychting M, Pukkala E, Tynes T, Hansen J, Nordby KC, Béranger R, Kauppinen T, Uuksulainen S, Wiebert P, Woldbæk T, Skakkebæk NE, Olsson A, Schüz J.

Occup Environ Med. 2015 Nov;72(11):805-11. doi: 10.1136/oemed-2015-102860. Epub 2015 Aug 24.

PMID:
26304777
73.

Association Between Use of Marijuana and Male Reproductive Hormones and Semen Quality: A Study Among 1,215 Healthy Young Men.

Gundersen TD, Jørgensen N, Andersson AM, Bang AK, Nordkap L, Skakkebæk NE, Priskorn L, Juul A, Jensen TK.

Am J Epidemiol. 2015 Sep 15;182(6):473-81. doi: 10.1093/aje/kwv135. Epub 2015 Aug 16.

PMID:
26283092
74.

Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012".

Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice LC, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross PS, Skakkebaek NE, Toppari J, Vandenberg LN, Woodruff TJ, Zoeller RT.

Regul Toxicol Pharmacol. 2015 Dec;73(3):1007-17. doi: 10.1016/j.yrtph.2015.07.026. Epub 2015 Jul 31.

75.

Testicular Cancer Pathogenesis, Diagnosis and Endocrine Aspects.

Rajpert-De Meyts E, Skakkebaek NE, Toppari J.

In: De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2018 Jan 7.

76.

Male reproductive disorders, diseases, and costs of exposure to endocrine-disrupting chemicals in the European Union.

Hauser R, Skakkebaek NE, Hass U, Toppari J, Juul A, Andersson AM, Kortenkamp A, Heindel JJ, Trasande L.

J Clin Endocrinol Metab. 2015 Apr;100(4):1267-77. doi: 10.1210/jc.2014-4325. Epub 2015 Mar 5.

77.

Estimating burden and disease costs of exposure to endocrine-disrupting chemicals in the European union.

Trasande L, Zoeller RT, Hass U, Kortenkamp A, Grandjean P, Myers JP, DiGangi J, Bellanger M, Hauser R, Legler J, Skakkebaek NE, Heindel JJ.

J Clin Endocrinol Metab. 2015 Apr;100(4):1245-55. doi: 10.1210/jc.2014-4324. Epub 2015 Mar 5.

78.

Contralateral biopsy in the management of testicular cancer: what we have learned and what we need to improve.

Rørth M, Grigor KM, Jørgensen N, Skakkebaek NE, Rajpert-De Meyts E.

Andrology. 2015 Jan;3(1):99-101. doi: 10.1111/andr.12008. No abstract available.

79.

Increasing international efforts to understand and conquer testicular germ cell cancer.

Rajpert-De Meyts E, Daugaard G, Almstrup K, Jørgensen A, Rørth M, Jørgensen N, von der Maase H, Skakkebaek NE.

Andrology. 2015 Jan;3(1):1-3. doi: 10.1111/andr.12010. No abstract available.

80.

Abundance of DLK1, differential expression of CYP11B1, CYP21A2 and MC2R, and lack of INSL3 distinguish testicular adrenal rest tumours from Leydig cell tumours.

Lottrup G, Nielsen JE, Skakkebæk NE, Juul A, Rajpert-De Meyts E.

Eur J Endocrinol. 2015 Apr;172(4):491-9. doi: 10.1530/EJE-14-0810. Epub 2015 Jan 21.

81.

Screening for carcinoma in situ in the contralateral testicle in patients with testicular cancer: a population-based study.

Kier MG, Lauritsen J, Almstrup K, Mortensen MS, Toft BG, Rajpert-De Meyts E, Skakkebaek NE, Rørth M, von der Maase H, Agerbaek M, Holm NV, Andersen KK, Dalton SO, Johansen C, Daugaard G.

Ann Oncol. 2015 Apr;26(4):737-42. doi: 10.1093/annonc/mdu585. Epub 2014 Dec 26.

PMID:
25542924
82.

A path forward in the debate over health impacts of endocrine disrupting chemicals.

Zoeller RT, Bergman Å, Becher G, Bjerregaard P, Bornman R, Brandt I, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Skakkebaek NE, Toppari J, Vandenberg LN.

Environ Health. 2014 Dec 22;13:118. doi: 10.1186/1476-069X-13-118.

83.

Habitual alcohol consumption associated with reduced semen quality and changes in reproductive hormones; a cross-sectional study among 1221 young Danish men.

Jensen TK, Gottschau M, Madsen JO, Andersson AM, Lassen TH, Skakkebæk NE, Swan SH, Priskorn L, Juul A, Jørgensen N.

BMJ Open. 2014 Oct 2;4(9):e005462. doi: 10.1136/bmjopen-2014-005462.

84.

Patterns of DNA damage response in intracranial germ cell tumors versus glioblastomas reflect cell of origin rather than brain environment: implications for the anti-tumor barrier concept and treatment.

Bartkova J, Hoei-Hansen CE, Krizova K, Hamerlik P, Skakkebæk NE, Rajpert-De Meyts E, Bartek J.

Mol Oncol. 2014 Dec;8(8):1667-78. doi: 10.1016/j.molonc.2014.07.001. Epub 2014 Jul 9.

85.

Possible fetal determinants of male infertility.

Juul A, Almstrup K, Andersson AM, Jensen TK, Jørgensen N, Main KM, Rajpert-De Meyts E, Toppari J, Skakkebæk NE.

Nat Rev Endocrinol. 2014 Sep;10(9):553-62. doi: 10.1038/nrendo.2014.97. Epub 2014 Jun 17. Review.

PMID:
24935122
86.

Expression patterns of DLK1 and INSL3 identify stages of Leydig cell differentiation during normal development and in testicular pathologies, including testicular cancer and Klinefelter syndrome.

Lottrup G, Nielsen JE, Maroun LL, Møller LM, Yassin M, Leffers H, Skakkebæk NE, Rajpert-De Meyts E.

Hum Reprod. 2014 Aug;29(8):1637-50. doi: 10.1093/humrep/deu124. Epub 2014 Jun 7.

PMID:
24908673
87.

Association of placenta organotin concentrations with growth and ponderal index in 110 newborn boys from Finland during the first 18 months of life: a cohort study.

Rantakokko P, Main KM, Wohlfart-Veje C, Kiviranta H, Airaksinen R, Vartiainen T, Skakkebæk NE, Toppari J, Virtanen HE.

Environ Health. 2014 Jun 5;13(1):45. doi: 10.1186/1476-069X-13-45.

88.

Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA.

Jensen TK, Swan S, Jørgensen N, Toppari J, Redmon B, Punab M, Drobnis EZ, Haugen TB, Zilaitiene B, Sparks AE, Irvine DS, Wang C, Jouannet P, Brazil C, Paasch U, Salzbrunn A, Skakkebæk NE, Andersson AM.

Hum Reprod. 2014 Aug;29(8):1801-9. doi: 10.1093/humrep/deu118. Epub 2014 Jun 3.

89.

Direct action of endocrine disrupting chemicals on human sperm.

Schiffer C, Müller A, Egeberg DL, Alvarez L, Brenker C, Rehfeld A, Frederiksen H, Wäschle B, Kaupp UB, Balbach M, Wachten D, Skakkebaek NE, Almstrup K, Strünker T.

EMBO Rep. 2014 Jul;15(7):758-65. doi: 10.15252/embr.201438869. Epub 2014 May 12.

90.

Urinary bisphenol A levels in young men: association with reproductive hormones and semen quality.

Lassen TH, Frederiksen H, Jensen TK, Petersen JH, Joensen UN, Main KM, Skakkebaek NE, Juul A, Jørgensen N, Andersson AM.

Environ Health Perspect. 2014 May;122(5):478-84. doi: 10.1289/ehp.1307309. Epub 2014 May 1.

91.

Special issue on the Impact of endocrine disrupters on reproductive health.

Andersson AM, Frederiksen H, Grigor KM, Toppari J, Skakkebæk NE.

Reproduction. 2014 Mar 4;147(4):E1. doi: 10.1530/REP-14-0060. Print 2014. No abstract available.

92.

Polychlorinated dibenzo-p-dioxins, furans, and biphenyls (PCDDs/PCDFs and PCBs) in breast milk and early childhood growth and IGF1.

Wohlfahrt-Veje C, Audouze K, Brunak S, Antignac JP, le Bizec B, Juul A, Skakkebæk NE, Main KM.

Reproduction. 2014 Mar 2;147(4):391-9. doi: 10.1530/REP-13-0422. Print 2014.

93.

Parental age at delivery and a man's semen quality.

Priskorn L, Jensen TK, Lindahl-Jacobsen R, Skakkebæk NE, Bostofte E, Eisenberg ML.

Hum Reprod. 2014 May;29(5):1097-102. doi: 10.1093/humrep/deu039. Epub 2014 Feb 26.

PMID:
24578474
94.

Lessons learned in andrology: what I have learned.

Skakkebaek NE.

Andrology. 2014 Mar;2(2):157-8. doi: 10.1111/j.2047-2927.2014.00203.x. No abstract available.

95.

Human urinary excretion of non-persistent environmental chemicals: an overview of Danish data collected between 2006 and 2012.

Frederiksen H, Jensen TK, Jørgensen N, Kyhl HB, Husby S, Skakkebæk NE, Main KM, Juul A, Andersson AM.

Reproduction. 2014 Mar 4;147(4):555-65. doi: 10.1530/REP-13-0522. Print 2014.

96.

Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men.

Joensen UN, Jørgensen N, Meldgaard M, Frederiksen H, Andersson AM, Menné T, Johansen JD, Carlsen BC, Stender S, Szecsi PB, Skakkebæk NE, Rajpert-De Meyts E, Thyssen JP.

Environ Health Perspect. 2014 Apr;122(4):345-50. doi: 10.1289/ehp.1306720. Epub 2014 Jan 3.

97.

Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis.

Kristensen DG, Nielsen JE, Jørgensen A, Skakkebæk NE, Rajpert-De Meyts E, Almstrup K.

Br J Cancer. 2014 Feb 4;110(3):668-78. doi: 10.1038/bjc.2013.727. Epub 2013 Nov 28.

98.

Phenotypic characterisation of immune cell infiltrates in testicular germ cell neoplasia.

Hvarness T, Nielsen JE, Almstrup K, Skakkebaek NE, Rajpert-De Meyts E, Claesson MH.

J Reprod Immunol. 2013 Dec;100(2):135-45. doi: 10.1016/j.jri.2013.10.005. Epub 2013 Nov 14.

PMID:
24290033
99.

No association between exposure to perfluorinated compounds and congenital cryptorchidism: a nested case-control study among 215 boys from Denmark and Finland.

Vesterholm Jensen D, Christensen J, Virtanen HE, Skakkebæk NE, Main KM, Toppari J, Veje CW, Andersson AM, Nielsen F, Grandjean P, Jensen TK.

Reproduction. 2014 Mar 2;147(4):411-7. doi: 10.1530/REP-13-0444. Print 2014.

100.

The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study.

Hart R, Doherty DA, Frederiksen H, Keelan JA, Hickey M, Sloboda D, Pennell CE, Newnham JP, Skakkebaek NE, Main KM.

Reproduction. 2014 Mar 2;147(4):379-90. doi: 10.1530/REP-13-0331. Print 2014.

101.

Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors.

Bergman Å, Andersson AM, Becher G, van den Berg M, Blumberg B, Bjerregaard P, Bornehag CG, Bornman R, Brandt I, Brian JV, Casey SC, Fowler PA, Frouin H, Giudice LC, Iguchi T, Hass U, Jobling S, Juul A, Kidd KA, Kortenkamp A, Lind M, Martin OV, Muir D, Ochieng R, Olea N, Norrgren L, Ropstad E, Ross PS, Rudén C, Scheringer M, Skakkebaek NE, Söder O, Sonnenschein C, Soto A, Swan S, Toppari J, Tyler CR, Vandenberg LN, Vinggaard AM, Wiberg K, Zoeller RT.

Environ Health. 2013 Aug 27;12:69. doi: 10.1186/1476-069X-12-69.

102.

Temporal variability in urinary excretion of bisphenol A and seven other phenols in spot, morning, and 24-h urine samples.

Lassen TH, Frederiksen H, Jensen TK, Petersen JH, Main KM, Skakkebæk NE, Jørgensen N, Kranich SK, Andersson AM.

Environ Res. 2013 Oct;126:164-70. doi: 10.1016/j.envres.2013.07.001. Epub 2013 Aug 8.

PMID:
23932849
103.

Urinary phthalates from 168 girls and boys measured twice a year during a 5-year period: associations with adrenal androgen levels and puberty.

Mouritsen A, Frederiksen H, Sørensen K, Aksglaede L, Hagen C, Skakkebaek NE, Main KM, Andersson AM, Juul A.

J Clin Endocrinol Metab. 2013 Sep;98(9):3755-64. doi: 10.1210/jc.2013-1284. Epub 2013 Jul 3.

PMID:
23824423
104.

Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells.

Kristensen DG, Skakkebæk NE, Rajpert-De Meyts E, Almstrup K.

Int J Dev Biol. 2013;57(2-4):309-17. doi: 10.1387/ijdb.130142ka. Review.

105.

Sperm concentration, testicular volume and age predict risk of carcinoma in situ in contralateral testis of men with testicular germ cell cancer.

Rud CN, Daugaard G, Rajpert-De Meyts E, Skakkebæk NE, Petersen JH, Jørgensen N.

J Urol. 2013 Dec;190(6):2074-80. doi: 10.1016/j.juro.2013.06.023. Epub 2013 Jun 14.

PMID:
23770148
106.

Semen quality of 1559 young men from four cities in Japan: a cross-sectional population-based study.

Iwamoto T, Nozawa S, Mieno MN, Yamakawa K, Baba K, Yoshiike M, Namiki M, Koh E, Kanaya J, Okuyama A, Matsumiya K, Tsujimura A, Kanetake H, Eguchi J, Skakkebaek NE, Vierula M, Toppari J, Jørgensen N.

BMJ Open. 2013 Apr 29;3(4). pii: e002222. doi: 10.1136/bmjopen-2012-002222. Print 2013.

107.

Image cytometer method for automated assessment of human spermatozoa concentration.

Egeberg DL, Kjaerulff S, Hansen C, Petersen JH, Glensbjerg M, Skakkebaek NE, Jørgensen N, Almstrup K.

Andrology. 2013 Jul;1(4):615-23. doi: 10.1111/j.2047-2927.2013.00082.x. Epub 2013 Apr 18.

108.

Identification of a novel androgen receptor mutation in a family with multiple components compatible with the testicular dysgenesis syndrome.

Lottrup G, Jørgensen A, Nielsen JE, Jørgensen N, Duno M, Vinggaard AM, Skakkebæk NE, Rajpert-De Meyts E.

J Clin Endocrinol Metab. 2013 Jun;98(6):2223-9. doi: 10.1210/jc.2013-1278. Epub 2013 Apr 15.

PMID:
23589523
109.

Association of sleep disturbances with reduced semen quality: a cross-sectional study among 953 healthy young Danish men.

Jensen TK, Andersson AM, Skakkebæk NE, Joensen UN, Blomberg Jensen M, Lassen TH, Nordkap L, Olesen IA, Hansen ÅM, Rod NH, Jørgensen N.

Am J Epidemiol. 2013 May 15;177(10):1027-37. doi: 10.1093/aje/kws420. Epub 2013 Apr 7.

PMID:
23568594
110.

The impact of endocrine disruption: a consensus statement on the state of the science.

Bergman A, Heindel JJ, Kasten T, Kidd KA, Jobling S, Neira M, Zoeller RT, Becher G, Bjerregaard P, Bornman R, Brandt I, Kortenkamp A, Muir D, Drisse MN, Ochieng R, Skakkebaek NE, Byléhn AS, Iguchi T, Toppari J, Woodruff TJ.

Environ Health Perspect. 2013 Apr;121(4):A104-6. doi: 10.1289/ehp.1205448. No abstract available.

111.

Association of placenta organotin concentrations with congenital cryptorchidism and reproductive hormone levels in 280 newborn boys from Denmark and Finland.

Rantakokko P, Main KM, Wohlfart-Veje C, Kiviranta H, Airaksinen R, Vartiainen T, Skakkebæk NE, Toppari J, Virtanen HE.

Hum Reprod. 2013 Jun;28(6):1647-60. doi: 10.1093/humrep/det040. Epub 2013 Mar 21.

PMID:
23520400
112.

Bisphenol A and other phenols in urine from Danish children and adolescents analyzed by isotope diluted TurboFlow-LC-MS/MS.

Frederiksen H, Aksglaede L, Sorensen K, Nielsen O, Main KM, Skakkebaek NE, Juul A, Andersson AM.

Int J Hyg Environ Health. 2013 Nov;216(6):710-20. doi: 10.1016/j.ijheh.2013.01.007. Epub 2013 Mar 13.

PMID:
23491025
113.

Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer.

Edsgärd D, Dalgaard MD, Weinhold N, Wesolowska-Andersen A, Rajpert-De Meyts E, Ottesen AM, Juul A, Skakkebæk NE, Skøt Jensen T, Gupta R, Leffers H, Brunak S.

Front Endocrinol (Lausanne). 2013 Jan 29;4:2. doi: 10.3389/fendo.2013.00002. eCollection 2013.

114.

Semen quality of fertile Japanese men: a cross-sectional population-based study of 792 men.

Iwamoto T, Nozawa S, Yoshiike M, Namiki M, Koh E, Kanaya J, Okuyama A, Matsumiya K, Tsujimura A, Komatsu K, Tsukamoto T, Itoh N, Mieno MN, Vierula M, Toppari J, Skakkebæk NE, Jørgensen N.

BMJ Open. 2013 Jan 25;3(1). pii: e002223. doi: 10.1136/bmjopen-2012-002223.

115.

47,XXY Klinefelter syndrome: clinical characteristics and age-specific recommendations for medical management.

Aksglaede L, Link K, Giwercman A, Jørgensen N, Skakkebaek NE, Juul A.

Am J Med Genet C Semin Med Genet. 2013 Feb 15;163C(1):55-63. doi: 10.1002/ajmg.c.31349. Epub 2013 Jan 23.

PMID:
23345262
116.

High dietary intake of saturated fat is associated with reduced semen quality among 701 young Danish men from the general population.

Jensen TK, Heitmann BL, Blomberg Jensen M, Halldorsson TI, Andersson AM, Skakkebæk NE, Joensen UN, Lauritsen MP, Christiansen P, Dalgård C, Lassen TH, Jørgensen N.

Am J Clin Nutr. 2013 Feb;97(2):411-8. doi: 10.3945/ajcn.112.042432. Epub 2012 Dec 26.

PMID:
23269819
117.

PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men.

Joensen UN, Veyrand B, Antignac JP, Blomberg Jensen M, Petersen JH, Marchand P, Skakkebæk NE, Andersson AM, Le Bizec B, Jørgensen N.

Hum Reprod. 2013 Mar;28(3):599-608. doi: 10.1093/humrep/des425. Epub 2012 Dec 18. Erratum in: Hum Reprod. 2014 Jul;29(7):1600.

PMID:
23250927
118.

A cohort effect on serum testosterone levels in Finnish men.

Perheentupa A, Mäkinen J, Laatikainen T, Vierula M, Skakkebaek NE, Andersson AM, Toppari J.

Eur J Endocrinol. 2013 Jan 17;168(2):227-33. doi: 10.1530/EJE-12-0288. Print 2013 Feb.

119.

Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias.

Christensen JS, Asklund C, Skakkebæk NE, Jørgensen N, Andersen HR, Jørgensen TM, Olsen LH, Høyer AP, Moesgaard J, Thorup J, Jensen TK.

J Urol. 2013 Mar;189(3):1077-82. doi: 10.1016/j.juro.2012.09.116. Epub 2012 Oct 2.

PMID:
23036983
120.

Low concentration of circulating antimüllerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study.

Hagen CP, Vestergaard S, Juul A, Skakkebæk NE, Andersson AM, Main KM, Hjøllund NH, Ernst E, Bonde JP, Anderson RA, Jensen TK.

Fertil Steril. 2012 Dec;98(6):1602-8.e2. doi: 10.1016/j.fertnstert.2012.08.008. Epub 2012 Sep 6.

PMID:
22959460
121.

Reproductive hormone profile and pubertal development in 14-year-old boys prenatally exposed to polychlorinated biphenyls.

Grandjean P, Grønlund C, Kjær IM, Jensen TK, Sørensen N, Andersson AM, Juul A, Skakkebæk NE, Budtz-Jørgensen E, Weihe P.

Reprod Toxicol. 2012 Dec;34(4):498-503. doi: 10.1016/j.reprotox.2012.07.005. Epub 2012 Jul 25.

122.

Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men.

Jørgensen N, Joensen UN, Jensen TK, Jensen MB, Almstrup K, Olesen IA, Juul A, Andersson AM, Carlsen E, Petersen JH, Toppari J, Skakkebæk NE.

BMJ Open. 2012 Jul 2;2(4). pii: e000990. doi: 10.1136/bmjopen-2012-000990. Print 2012.

123.

Trends in rates of natural conceptions among Danish women born during 1960-1984.

Lassen TH, Sobotka T, Jensen TK, Jacobsen R, Erb K, Skakkebæk NE.

Hum Reprod. 2012 Sep;27(9):2815-22. doi: 10.1093/humrep/des207. Epub 2012 Jun 26.

PMID:
22736324
124.

Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society.

Zoeller RT, Brown TR, Doan LL, Gore AC, Skakkebaek NE, Soto AM, Woodruff TJ, Vom Saal FS.

Endocrinology. 2012 Sep;153(9):4097-110. doi: 10.1210/en.2012-1422. Epub 2012 Jun 25.

125.

Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age.

Andersen HR, Wohlfahrt-Veje C, Dalgård C, Christiansen L, Main KM, Nellemann C, Murata K, Jensen TK, Skakkebæk NE, Grandjean P.

PLoS One. 2012;7(5):e36830. doi: 10.1371/journal.pone.0036830. Epub 2012 May 15.

126.

Sunscreens: are they beneficial for health? An overview of endocrine disrupting properties of UV-filters.

Krause M, Klit A, Blomberg Jensen M, Søeborg T, Frederiksen H, Schlumpf M, Lichtensteiger W, Skakkebaek NE, Drzewiecki KT.

Int J Androl. 2012 Jun;35(3):424-36. doi: 10.1111/j.1365-2605.2012.01280.x. Review.

PMID:
22612478
127.

Urinary phthalate excretion in 555 healthy Danish boys with and without pubertal gynaecomastia.

Mieritz MG, Frederiksen H, Sørensen K, Aksglaede L, Mouritsen A, Hagen CP, Skakkebaek NE, Andersson AM, Juul A.

Int J Androl. 2012 Jun;35(3):227-35. doi: 10.1111/j.1365-2605.2012.01279.x.

PMID:
22612475
128.

Special issue on the impact of endocrine disrupters on reproductive health.

Andersson AM, Bay K, Grigor KM, Rajpert-De Meyts E, Skakkebaek NE.

Int J Androl. 2012 Jun;35(3):215. doi: 10.1111/j.1365-2605.2012.01274.x. No abstract available.

PMID:
22612474
129.

45,X/46,XY mosaicism: phenotypic characteristics, growth, and reproductive function--a retrospective longitudinal study.

Lindhardt Johansen M, Hagen CP, Rajpert-De Meyts E, Kjærgaard S, Petersen BL, Skakkebæk NE, Main KM, Juul A.

J Clin Endocrinol Metab. 2012 Aug;97(8):E1540-9. doi: 10.1210/jc.2012-1388. Epub 2012 May 17.

PMID:
22605431
130.

Association between chemical pattern in breast milk and congenital cryptorchidism: modelling of complex human exposures.

Krysiak-Baltyn K, Toppari J, Skakkebaek NE, Jensen TS, Virtanen HE, Schramm KW, Shen H, Vartiainen T, Kiviranta H, Taboureau O, Audouze K, Brunak S, Main KM.

Int J Androl. 2012 Jun;35(3):294-302. doi: 10.1111/j.1365-2605.2012.01268.x. Epub 2012 Apr 23.

PMID:
22519522
131.

Increasing trends in childlessness in recent birth cohorts - a registry-based study of the total Danish male population born from 1945 to 1980.

Priskorn L, Holmboe SA, Jacobsen R, Jensen TK, Lassen TH, Skakkebaek NE.

Int J Androl. 2012 Jun;35(3):449-55. doi: 10.1111/j.1365-2605.2012.01265.x. Epub 2012 Apr 10.

PMID:
22489560
132.

High urinary phthalate concentration associated with delayed pubarche in girls.

Frederiksen H, Sørensen K, Mouritsen A, Aksglaede L, Hagen CP, Petersen JH, Skakkebaek NE, Andersson AM, Juul A.

Int J Androl. 2012 Jun;35(3):216-26. doi: 10.1111/j.1365-2605.2012.01260.x. Epub 2012 Mar 19.

PMID:
22428786
133.

Expression of the vitamin D metabolizing enzyme CYP24A1 at the annulus of human spermatozoa may serve as a novel marker of semen quality.

Blomberg Jensen M, Jørgensen A, Nielsen JE, Bjerrum PJ, Skalkam M, Petersen JH, Egeberg DL, Bangsbøll S, Andersen AN, Skakkebaek NE, Juul A, Rajpert-De Meyts E, Dissing S, Leffers H, Jørgensen N.

Int J Androl. 2012 Aug;35(4):499-510. doi: 10.1111/j.1365-2605.2012.01256.x. Epub 2012 Mar 9.

PMID:
22404291
134.

Early breast development in girls after prenatal exposure to non-persistent pesticides.

Wohlfahrt-Veje C, Andersen HR, Schmidt IM, Aksglaede L, Sørensen K, Juul A, Jensen TK, Grandjean P, Skakkebaek NE, Main KM.

Int J Androl. 2012 Jun;35(3):273-82. doi: 10.1111/j.1365-2605.2011.01244.x. Epub 2012 Mar 9.

PMID:
22404257
135.

Smaller genitals at school age in boys whose mothers were exposed to non-persistent pesticides in early pregnancy.

Wohlfahrt-Veje C, Andersen HR, Jensen TK, Grandjean P, Skakkebaek NE, Main KM.

Int J Androl. 2012 Jun;35(3):265-72. doi: 10.1111/j.1365-2605.2012.01252.x. Epub 2012 Mar 6.

PMID:
22394112
136.

The relationship between anogenital distance and reproductive hormone levels in adult men.

Eisenberg ML, Jensen TK, Walters RC, Skakkebaek NE, Lipshultz LI.

J Urol. 2012 Feb;187(2):594-8. doi: 10.1016/j.juro.2011.10.041. Epub 2011 Dec 15.

PMID:
22177168
137.

[Antioxidants and male subfertility--a survey of a Cochrane review].

Jensen TK, Skakkebæk NE, Jørgensen N, Blomberg Jensen M, Juul A.

Ugeskr Laeger. 2011 Dec 12;173(50):3253-5. Review. Danish.

PMID:
22153208
138.

Associations between congenital cryptorchidism in newborn boys and levels of dioxins and PCBs in placenta.

Virtanen HE, Koskenniemi JJ, Sundqvist E, Main KM, Kiviranta H, Tuomisto JT, Tuomisto J, Viluksela M, Vartiainen T, Skakkebaek NE, Toppari J.

Int J Androl. 2012 Jun;35(3):283-93. doi: 10.1111/j.1365-2605.2011.01233.x. Epub 2011 Dec 13.

139.

A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation.

Dalgaard MD, Weinhold N, Edsgärd D, Silver JD, Pers TH, Nielsen JE, Jørgensen N, Juul A, Gerds TA, Giwercman A, Giwercman YL, Cohn-Cedermark G, Virtanen HE, Toppari J, Daugaard G, Jensen TS, Brunak S, Rajpert-De Meyts E, Skakkebæk NE, Leffers H, Gupta R.

J Med Genet. 2012 Jan;49(1):58-65. doi: 10.1136/jmedgenet-2011-100174. Epub 2011 Dec 3.

140.

Lower birth weight and increased body fat at school age in children prenatally exposed to modern pesticides: a prospective study.

Wohlfahrt-Veje C, Main KM, Schmidt IM, Boas M, Jensen TK, Grandjean P, Skakkebæk NE, Andersen HR.

Environ Health. 2011 Sep 20;10:79. doi: 10.1186/1476-069X-10-79.

141.

The exposure of fetuses and children to endocrine disrupting chemicals: a European Society for Paediatric Endocrinology (ESPE) and Pediatric Endocrine Society (PES) call to action statement.

Skakkebaek NE, Toppari J, Söder O, Gordon CM, Divall S, Draznin M.

J Clin Endocrinol Metab. 2011 Oct;96(10):3056-8. doi: 10.1210/jc.2011-1269. Epub 2011 Aug 10.

PMID:
21832106
142.

Pathogenesis of testicular carcinoma in situ and germ cell cancer: still more questions than answers.

Rajpert-De Meyts E, Skakkebaek NE.

Int J Androl. 2011 Aug;34(4 Pt 2):e2-6. doi: 10.1111/j.1365-2605.2011.01213.x. No abstract available.

PMID:
21790651
143.

Proceedings of the 7th Copenhagen Workshop on Testicular Carcinoma in situ and Germ Cell Cancer, 13-15 October 2010.

Rajpert-De Meyts E, Grigor KM, Skakkebaek NE.

Int J Androl. 2011 Aug;34(4 Pt 2):e1. doi: 10.1111/j.1365-2605.2011.01212.x. No abstract available.

PMID:
21790649
144.

Sperm counts, data responsibility, and good scientific practice.

Skakkebaek NE, Andersson AM, Juul A, Jensen TK, Almstrup K, Toppari J, Jørgensen N.

Epidemiology. 2011 Sep;22(5):620-1. doi: 10.1097/EDE.0b013e318229ec01. No abstract available.

PMID:
21730861
145.

Development: disorders of sex development-the tip of the iceberg?

Juul A, Main KM, Skakkebaek NE.

Nat Rev Endocrinol. 2011 Jul 5;7(9):504-5. doi: 10.1038/nrendo.2011.115. No abstract available.

PMID:
21727912
146.

Screening of subfertile men for testicular carcinoma in situ by an automated image analysis-based cytological test of the ejaculate.

Almstrup K, Lippert M, Mogensen HO, Nielsen JE, Hansen JD, Daugaard G, Jørgensen N, Foged NT, Skakkebaek NE, Rajpert-De Meyts E.

Int J Androl. 2011 Aug;34(4 Pt 2):e21-30; discussion e30-1. doi: 10.1111/j.1365-2605.2011.01192.x. Epub 2011 Jun 22.

PMID:
21696398
147.

Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information.

Edsgärd D, Scheel M, Hansen NT, Ralfkiaer U, Jensen TS, Skakkebaek NE, Brunak S, Gupta R, Rajpert-De Meyts E, Ottesen AM.

Int J Androl. 2011 Aug;34(4 Pt 2):e122-32. doi: 10.1111/j.1365-2605.2011.01188.x. Epub 2011 Jun 22.

PMID:
21696394
148.

Klinefelter syndrome: the forgotten syndrome: basic and clinical questions posed to an international group of scientists.

Juul A, Aksglaede L, Bay K, Grigor KM, Skakkebaek NE.

Acta Paediatr. 2011 Jun;100(6):791-2. doi: 10.1111/j.1651-2227.2011.02283.x. No abstract available.

PMID:
21521364
149.

A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples.

Nielsen JE, Kristensen DM, Almstrup K, Jørgensen A, Olesen IA, Jacobsen GK, Horn T, Skakkebaek NE, Leffers H, Rajpert-De Meyts E.

Andrologia. 2012 Apr;44(2):78-85. doi: 10.1111/j.1439-0272.2010.01108.x. Epub 2011 Feb 16.

PMID:
21486421
150.

Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: estimation of daily phthalate intake.

Frederiksen H, Aksglaede L, Sorensen K, Skakkebaek NE, Juul A, Andersson AM.

Environ Res. 2011 Jul;111(5):656-63. doi: 10.1016/j.envres.2011.03.005. Epub 2011 Mar 22.

PMID:
21429484
151.

Testicular descent: INSL3, testosterone, genes and the intrauterine milieu.

Bay K, Main KM, Toppari J, Skakkebæk NE.

Nat Rev Urol. 2011 Apr;8(4):187-96. doi: 10.1038/nrurol.2011.23. Epub 2011 Mar 15. Review.

PMID:
21403659
152.

Recent adverse trends in semen quality and testis cancer incidence among Finnish men.

Jørgensen N, Vierula M, Jacobsen R, Pukkala E, Perheentupa A, Virtanen HE, Skakkebaek NE, Toppari J.

Int J Androl. 2011 Aug;34(4 Pt 2):e37-48. doi: 10.1111/j.1365-2605.2010.01133.x. Epub 2011 Mar 2.

153.

Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience.

Aksglaede L, Skakkebaek NE, Almstrup K, Juul A.

Acta Paediatr. 2011 Jun;100(6):793-806. doi: 10.1111/j.1651-2227.2011.02246.x. Epub 2011 Mar 28.

PMID:
21362037
154.

Prenatal and adult exposures to smoking are associated with adverse effects on reproductive hormones, semen quality, final height and body mass index.

Ravnborg TL, Jensen TK, Andersson AM, Toppari J, Skakkebaek NE, Jørgensen N.

Hum Reprod. 2011 May;26(5):1000-11. doi: 10.1093/humrep/der011. Epub 2011 Feb 18.

PMID:
21335416
155.

Semen quality and reproductive hormone levels in men from Southern Spain.

Fernandez MF, Duran I, Olea N, Avivar C, Vierula M, Toppari J, Skakkebaek NE, Jørgensen N.

Int J Androl. 2012 Feb;35(1):1-10. doi: 10.1111/j.1365-2605.2010.01131.x. Epub 2011 Feb 18.

156.

Sex differences in the vaccine-specific and non-targeted effects of vaccines.

Flanagan KL, Klein SL, Skakkebaek NE, Marriott I, Marchant A, Selin L, Fish EN, Prentice AM, Whittle H, Benn CS, Aaby P.

Vaccine. 2011 Mar 16;29(13):2349-54. doi: 10.1016/j.vaccine.2011.01.071. Epub 2011 Feb 5.

PMID:
21300095
157.

Serum concentrations of Anti-Müllerian Hormone (AMH) in 95 patients with Klinefelter syndrome with or without cryptorchidism.

Aksglaede L, Christiansen P, Sørensen K, Boas M, Linneberg A, Main KM, Andersson AM, Skakkebaek NE, Juul A.

Acta Paediatr. 2011 Jun;100(6):839-45. doi: 10.1111/j.1651-2227.2011.02148.x. Epub 2011 Feb 25.

PMID:
21251056
158.

Many putative endocrine disruptors inhibit prostaglandin synthesis.

Kristensen DM, Skalkam ML, Audouze K, Lesné L, Desdoits-Lethimonier C, Frederiksen H, Brunak S, Skakkebæk NE, Jégou B, Hansen JB, Junker S, Leffers H.

Environ Health Perspect. 2011 Apr;119(4):534-41. doi: 10.1289/ehp.1002635. Epub 2010 Nov 16.

159.

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.

Kristensen DM, Hass U, Lesné L, Lottrup G, Jacobsen PR, Desdoits-Lethimonier C, Boberg J, Petersen JH, Toppari J, Jensen TK, Brunak S, Skakkebaek NE, Nellemann C, Main KM, Jégou B, Leffers H.

Hum Reprod. 2011 Jan;26(1):235-44. doi: 10.1093/humrep/deq323. Epub 2010 Nov 8.

PMID:
21059752
160.

Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection.

Toppari J, Virtanen HE, Main KM, Skakkebaek NE.

Birth Defects Res A Clin Mol Teratol. 2010 Oct;88(10):910-9. doi: 10.1002/bdra.20707. Review.

PMID:
20865786
161.

Changes in anti-Müllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years.

Aksglaede L, Sørensen K, Boas M, Mouritsen A, Hagen CP, Jensen RB, Petersen JH, Linneberg A, Andersson AM, Main KM, Skakkebæk NE, Juul A.

J Clin Endocrinol Metab. 2010 Dec;95(12):5357-64. doi: 10.1210/jc.2010-1207. Epub 2010 Sep 15.

PMID:
20843948
162.

Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells.

Almstrup K, Nielsen JE, Mlynarska O, Jansen MT, Jørgensen A, Skakkebæk NE, Rajpert-De Meyts E.

Br J Cancer. 2010 Oct 12;103(8):1269-76. doi: 10.1038/sj.bjc.6605880. Epub 2010 Sep 7.

163.

Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth.

Boas M, Frederiksen H, Feldt-Rasmussen U, Skakkebæk NE, Hegedüs L, Hilsted L, Juul A, Main KM.

Environ Health Perspect. 2010 Oct;118(10):1458-64. doi: 10.1289/ehp.0901331. Epub 2010 Jul 9.

164.

Testicular non-seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Schmoll HJ, Jordan K, Huddart R, Pes MP, Horwich A, Fizazi K, Kataja V; ESMO Guidelines Working Group.

Ann Oncol. 2010 May;21 Suppl 5:v147-54. doi: 10.1093/annonc/mdq177. No abstract available.

PMID:
20555066
165.

Testicular seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Schmoll HJ, Jordan K, Huddart R, Pes MP, Horwich A, Fizazi K, Kataja V; ESMO Guidelines Working Group.

Ann Oncol. 2010 May;21 Suppl 5:v140-6. doi: 10.1093/annonc/mdq176. No abstract available.

PMID:
20555065
166.

Genital anomalies in boys and the environment.

Main KM, Skakkebaek NE, Virtanen HE, Toppari J.

Best Pract Res Clin Endocrinol Metab. 2010 Apr;24(2):279-89. doi: 10.1016/j.beem.2009.10.003. Review.

PMID:
20541152
167.

Hypothesis: exposure to endocrine-disrupting chemicals may interfere with timing of puberty.

Mouritsen A, Aksglaede L, Sørensen K, Mogensen SS, Leffers H, Main KM, Frederiksen H, Andersson AM, Skakkebaek NE, Juul A.

Int J Androl. 2010 Apr;33(2):346-59. doi: 10.1111/j.1365-2605.2010.01051.x. Review.

PMID:
20487042
168.

Proceedings of the 5th Copenhagen Workshop on endocrine disrupters: ubiquitous endocrine disrupters and possible human health effects. Preface.

Andersson AM, Bay K, Grigor KM, Toppari J, Skakkebaek NE.

Int J Androl. 2010 Apr;33(2):251. doi: 10.1111/j.1365-2605.2010.01055.x. No abstract available.

PMID:
20487041
169.

Caffeine intake and semen quality in a population of 2,554 young Danish men.

Jensen TK, Swan SH, Skakkebaek NE, Rasmussen S, Jørgensen N.

Am J Epidemiol. 2010 Apr 15;171(8):883-91. doi: 10.1093/aje/kwq007. Epub 2010 Mar 25.

PMID:
20338976
170.

Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract.

Blomberg Jensen M, Nielsen JE, Jørgensen A, Rajpert-De Meyts E, Kristensen DM, Jørgensen N, Skakkebaek NE, Juul A, Leffers H.

Hum Reprod. 2010 May;25(5):1303-11. doi: 10.1093/humrep/deq024. Epub 2010 Feb 18.

PMID:
20172873
171.

Testicular germ cell cancer incidence in an immigration perspective, Denmark, 1978 to 2003.

Schmiedel S, Schüz J, Skakkebaek NE, Johansen C.

J Urol. 2010 Apr;183(4):1378-82. doi: 10.1016/j.juro.2009.12.058. Epub 2010 Feb 19.

PMID:
20171682
172.

Serum inhibin-b in fertile men is strongly correlated with low but not high sperm counts: a coordinated study of 1,797 European and US men.

Jørgensen N, Liu F, Andersson AM, Vierula M, Irvine DS, Auger J, Brazil CK, Drobnis EZ, Jensen TK, Jouannet P, Overstreet JW, Redmon JB, Sparks A, Toppari J, Wang C, Skakkebæk NE, Swan SH.

Fertil Steril. 2010 Nov;94(6):2128-34. doi: 10.1016/j.fertnstert.2009.12.051. Epub 2010 Feb 10.

173.

Testicular dysgenesis syndrome comprises some but not all cases of hypospadias and impaired spermatogenesis.

Jørgensen N, Rajpert-De Meyts E, Main KM, Skakkebaek NE.

Int J Androl. 2010 Apr;33(2):298-303. doi: 10.1111/j.1365-2605.2009.01050.x. Epub 2010 Feb 4.

PMID:
20132348
174.

OCT4 and downstream factors are expressed in human somatic urogenital epithelia and in culture of epididymal spheres.

Kristensen DM, Nielsen JE, Kalisz M, Dalgaard MD, Audouze K, Larsen ME, Jacobsen GK, Horn T, Brunak S, Skakkebaek NE, Leffers H.

Mol Hum Reprod. 2010 Nov;16(11):835-45. doi: 10.1093/molehr/gaq008. Epub 2010 Jan 31.

PMID:
20123703
175.

Normal reference ranges for semen quality and their relations to fecundity.

Skakkebaek NE.

Asian J Androl. 2010 Jan;12(1):95-8. doi: 101.1038/aja.2008.43.

176.

Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method.

Courant F, Aksglaede L, Antignac JP, Monteau F, Sorensen K, Andersson AM, Skakkebaek NE, Juul A, Bizec BL.

J Clin Endocrinol Metab. 2010 Jan;95(1):82-92. doi: 10.1210/jc.2009-1140. Epub 2009 Nov 20.

PMID:
19933393
177.

Gene expression profiles of mouse spermatogenesis during recovery from irradiation.

Shah FJ, Tanaka M, Nielsen JE, Iwamoto T, Kobayashi S, Skakkebaek NE, Leffers H, Almstrup K.

Reprod Biol Endocrinol. 2009 Nov 19;7:130. doi: 10.1186/1477-7827-7-130.

178.

Early puberty in internationally adopted girls: hormonal and clinical markers of puberty in 276 girls examined biannually over two years.

Teilmann G, Petersen JH, Gormsen M, Damgaard K, Skakkebaek NE, Jensen TK.

Horm Res. 2009;72(4):236-46. doi: 10.1159/000236085. Epub 2009 Sep 29.

PMID:
19786795
179.

Country-specific chemical signatures of persistent environmental compounds in breast milk.

Krysiak-Baltyn K, Toppari J, Skakkebaek NE, Jensen TS, Virtanen HE, Schramm KW, Shen H, Vartiainen T, Kiviranta H, Taboureau O, Brunak S, Main KM.

Int J Androl. 2010 Apr;33(2):270-8. doi: 10.1111/j.1365-2605.2009.00996.x. Epub 2009 Sep 24.

PMID:
19780864
180.

Narrow intra-individual variation of maternal thyroid function in pregnancy based on a longitudinal study on 132 women.

Boas M, Forman JL, Juul A, Feldt-Rasmussen U, Skakkebaek NE, Hilsted L, Chellakooty M, Larsen T, Larsen JF, Petersen JH, Main KM.

Eur J Endocrinol. 2009 Dec;161(6):903-10. doi: 10.1530/EJE-09-0579. Epub 2009 Sep 22.

181.

Association of thyroid gland volume, serum insulin-like growth factor-I, and anthropometric variables in euthyroid prepubertal children.

Boas M, Hegedüs L, Feldt-Rasmussen U, Skakkebaek NE, Hilsted L, Main KM.

J Clin Endocrinol Metab. 2009 Oct;94(10):4031-5. doi: 10.1210/jc.2009-0939. Epub 2009 Jul 14.

PMID:
19602556
182.

Do perfluoroalkyl compounds impair human semen quality?

Joensen UN, Bossi R, Leffers H, Jensen AA, Skakkebaek NE, Jørgensen N.

Environ Health Perspect. 2009 Jun;117(6):923-7. doi: 10.1289/ehp.0800517. Epub 2009 Mar 2.

183.

Low semen volume in 47 adolescents and adults with 47,XXY Klinefelter or 46,XX male syndrome.

Aksglaede L, Jørgensen N, Skakkebaek NE, Juul A.

Int J Androl. 2009 Aug;32(4):376-84. doi: 10.1111/j.1365-2605.2008.00921.x. Epub 2008 Oct 21.

PMID:
19515177
184.

Acquired cryptorchidism is frequent in infancy and childhood.

Wohlfahrt-Veje C, Boisen KA, Boas M, Damgaard IN, Kai CM, Schmidt IM, Chellakooty M, Suomi AM, Toppari J, Skakkebaek NE, Main KM.

Int J Androl. 2009 Aug;32(4):423-8. doi: 10.1111/j.1365-2605.2009.00946.x.

PMID:
19515170
185.

Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte.

Sonne SB, Almstrup K, Dalgaard M, Juncker AS, Edsgard D, Ruban L, Harrison NJ, Schwager C, Abdollahi A, Huber PE, Brunak S, Gjerdrum LM, Moore HD, Andrews PW, Skakkebaek NE, Rajpert-De Meyts E, Leffers H.

Cancer Res. 2009 Jun 15;69(12):5241-50. doi: 10.1158/0008-5472.CAN-08-4554. Epub 2009 Jun 2.

186.

Recent decline in age at breast development: the Copenhagen Puberty Study.

Aksglaede L, Sørensen K, Petersen JH, Skakkebaek NE, Juul A.

Pediatrics. 2009 May;123(5):e932-9. doi: 10.1542/peds.2008-2491.

PMID:
19403485
187.

Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection.

Main KM, Skakkebaek NE, Toppari J.

Endocr Dev. 2009;14:167-73. doi: 10.1159/000207485. Epub 2009 Feb 27. Review.

PMID:
19293583
188.

Semen quality, reproductive hormones and fertility of men operated for hypospadias.

Asklund C, Jensen TK, Main KM, Sobotka T, Skakkebaek NE, Jørgensen N.

Int J Androl. 2010 Feb;33(1):80-7. doi: 10.1111/j.1365-2605.2009.00957.x. Epub 2009 Mar 5.

PMID:
19281491
189.

Is there a problem with male reproduction?

Joensen UN, Skakkebaek NE, Jørgensen N.

Nat Clin Pract Endocrinol Metab. 2009 Mar;5(3):144-5. doi: 10.1038/ncpendmet1077. No abstract available.

PMID:
19229232
190.

Testicular dysgenesis syndrome: foetal origin of adult reproductive problems.

Wohlfahrt-Veje C, Main KM, Skakkebaek NE.

Clin Endocrinol (Oxf). 2009 Oct;71(4):459-65. doi: 10.1111/j.1365-2265.2009.03545.x. Epub 2009 Feb 16. Review.

PMID:
19222487
191.

Re: The true incidence of cryptorchidism in Denmark: D. Cortes, E. M. Kjellberg, M. Breddam and J. Thorup, J Urol 2008; 179: 314-318.

Main KM, Skakkebaek NE, Toppari J.

J Urol. 2009 Feb;181(2):922-4. doi: 10.1016/j.juro.2008.10.048. Epub 2008 Dec 24. No abstract available.

PMID:
19110272
192.

Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.

Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice LC, Guillette LJ Jr.

Fertil Steril. 2008 Oct;90(4):911-40. doi: 10.1016/j.fertnstert.2008.08.067. Review.

193.

Risk factors for congenital cryptorchidism in a prospective birth cohort study.

Damgaard IN, Jensen TK; Nordic Cryptorchidism Study Group, Petersen JH, Skakkebaek NE, Toppari J, Main KM.

PLoS One. 2008 Aug 25;3(8):e3051. doi: 10.1371/journal.pone.0003051.

194.

Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer.

Blomberg Jensen M, Leffers H, Petersen JH, Daugaard G, Skakkebaek NE, Rajpert-De Meyts E.

Ann Oncol. 2008 Nov;19(11):1910-4. doi: 10.1093/annonc/mdn407. Epub 2008 Jul 15.

PMID:
18632724
195.

Insulin-like factor 3 levels in second-trimester amniotic fluid.

Bay K, Cohen AS, Jørgensen FS, Jørgensen C, Lind AM, Skakkebaek NE, Andersson AM.

J Clin Endocrinol Metab. 2008 Oct;93(10):4048-51. doi: 10.1210/jc.2008-0358. Epub 2008 Jul 8.

PMID:
18611973
196.

Re: Niels J. van Casteren, Hans Stoop, Gert R. Dohle, Ronald de Wit, J. Wolter Oosterhuis, Leendert H.J. Looijenga. Noninvasive detection of testicular carcinoma in situ in semen using OCT3/4. Eur Urol 2008;54:153-60.

Hoei-Hansen CE, Almstrup K, Skakkebaek NE, Rajpert-De Meyts E.

Eur Urol. 2009 Apr;55(4):e67-8. doi: 10.1016/j.eururo.2008.04.041. Epub 2008 Apr 25. No abstract available.

PMID:
18456394
197.

Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number.

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