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Items: 1 to 200 of 323

1.

Pediatric cancer families' participation in whole-genome sequencing research in Denmark: Parent perspectives.

Byrjalsen A, Stoltze U, Wadt K, Hjalgrim LL, Gerdes AM, Schmiegelow K, Wahlberg A.

Eur J Cancer Care (Engl). 2018 Jul 17:e12877. doi: 10.1111/ecc.12877. [Epub ahead of print]

PMID:
30016002
2.

Comparing osteonecrosis clinical phenotype, timing, and risk factors in children and young adults treated for acute lymphoblastic leukemia.

Mogensen SS, Harila-Saari A, Mäkitie O, Myrberg IH, Niinimäki R, Vestli A, Hafsteinsdottir S, Griškevicius L, Saks K, Hallböök H, Retpen J, Helt LR, Toft N, Schmiegelow K, Frandsen TL; Nordic Society of Paediatric Haematology and Oncology (NOPHO) group.

Pediatr Blood Cancer. 2018 Jun 26:e27300. doi: 10.1002/pbc.27300. [Epub ahead of print]

PMID:
29943905
3.

Sperm DNA Integrity is Unaffected by Thiopurine Treatment in Men with Inflammatory Bowel Disease.

Grosen A, Nersting J, Bungum M, Christensen LA, Schmiegelow K, Spanò M, Julsgaard M, Cordelli E, Leter G, Larsen PB, Hvas CL, Kelsen J.

J Crohns Colitis. 2018 Jun 16. doi: 10.1093/ecco-jcc/jjy086. [Epub ahead of print]

PMID:
29917107
4.

The cost of cure.

Schmiegelow K, Frandsen TL.

Lancet Haematol. 2018 Jun 12. pii: S2352-3026(18)30070-X. doi: 10.1016/S2352-3026(18)30070-X. [Epub ahead of print] No abstract available.

PMID:
29907548
5.

Testing physical function in children undergoing intense cancer treatment-a RESPECT feasibility study.

Nielsen MKF, Christensen JF, Frandsen TL, Thorsteinsson T, Andersen LB, Christensen KB, Nersting J, Faber M, Schmiegelow K, Larsen HB.

Pediatr Blood Cancer. 2018 Aug;65(8):e27100. doi: 10.1002/pbc.27100. Epub 2018 May 9.

PMID:
29741279
6.

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.

Hrusak O, de Haas V, Stancikova J, Vakrmanova B, Janotova I, Mejstrikova E, Capek V, Trka J, Zaliova M, Luks A, Bleckmann K, Möricke A, Irving J, Konatkowska B, Alexander TB, Inaba H, Schmiegelow K, Stokley S, Zemanova Z, Moorman AV, Rossi JG, Felice MS, Dalla-Pozza L, Morales J, Dworzak M, Buldini B, Basso G, Campbell M, Cabrera ME, Marinov N, Elitzur S, Izraeli S, Luria D, Feuerstein T, Kolenova A, Svec P, Kreminska O, Rabin KR, Polychronopoulou S, da Costa E, Marquart HV, Kattamis A, Ratei R, Reinhardt D, Choi JK, Schrappe M, Stary J.

Blood. 2018 Jul 19;132(3):264-276. doi: 10.1182/blood-2017-12-821363. Epub 2018 May 2.

PMID:
29720486
7.

[Germ line mutations causing paediatric cancer predisposition syndromes are common in children and adolescents with cancer].

Stoltze UK, Byrjalsen A, Hjalgrim LL, Wahlberg A, Gupta R, Gerdes AM, Wadt K, Schmiegelow K.

Ugeskr Laeger. 2018 Apr 23;180(17). pii: V07170566. Danish.

PMID:
29717702
8.

Association between body mass index and pancreatitis in children with acute lymphoblastic leukemia.

Mogensen PR, Wolthers BO, Grell K, Schmiegelow K, Frandsen TL.

Pediatr Blood Cancer. 2018 Aug;65(8):e27071. doi: 10.1002/pbc.27071. Epub 2018 Apr 18. No abstract available.

PMID:
29667750
9.

Thromboembolism in acute lymphoblastic leukemia: results of NOPHO ALL2008 protocol treatment in patients aged 1 to 45 years.

Rank CU, Toft N, Tuckuviene R, Grell K, Nielsen OJ, Frandsen TL, Marquart HVH, Albertsen BK, Tedgård U, Hallböök H, Ruud E, Jarvis KB, Quist-Paulsen P, Huttunen P, Wartiovaara-Kautto U, Jónsson ÓG, Trakymiene SS, Griškevičius L, Saks K, Punab M, Schmiegelow K.

Blood. 2018 May 31;131(22):2475-2484. doi: 10.1182/blood-2018-01-827949. Epub 2018 Apr 16.

10.

All-cause mortality rates and home deaths decreased in children with life-limiting diagnoses in Denmark between 1994 and 2014.

Lykke C, Ekholm O, Schmiegelow K, Olsen M, Sjøgren P.

Acta Paediatr. 2018 Mar 22. doi: 10.1111/apa.14331. [Epub ahead of print]

PMID:
29566441
11.

Interactions Between Thiopurine Metabolites, Adalimumab, and Antibodies Against Adalimumab in Previously Infliximab-Treated Patients with Inflammatory Bowel Disease.

Holmstrøm RB, Mogensen DV, Brynskov J, Ainsworth MA, Nersting J, Schmiegelow K, Steenholdt C.

Dig Dis Sci. 2018 Jun;63(6):1583-1591. doi: 10.1007/s10620-018-5020-9. Epub 2018 Mar 21.

PMID:
29564674
12.

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia.

Borssén M, Nordlund J, Haider Z, Landfors M, Larsson P, Kanerva J, Schmiegelow K, Flaegstad T, Jónsson ÓG, Frost BM, Palle J, Forestier E, Heyman M, Hultdin M, Lönnerholm G, Degerman S.

Clin Epigenetics. 2018 Mar 5;10:31. doi: 10.1186/s13148-018-0466-3. eCollection 2018.

13.

MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia.

Evensen NA, Madhusoodhan PP, Meyer J, Saliba J, Chowdhury A, Araten DJ, Nersting J, Bhatla T, Vincent TL, Teachey D, Hunger SP, Yang J, Schmiegelow K, Carroll WL.

Haematologica. 2018 May;103(5):830-839. doi: 10.3324/haematol.2017.176362. Epub 2018 Feb 15.

14.

Role of TPMT and ITPA variants in mercaptopurine disposition.

Gerbek T, Ebbesen M, Nersting J, Frandsen TL, Appell ML, Schmiegelow K.

Cancer Chemother Pharmacol. 2018 Mar;81(3):579-586. doi: 10.1007/s00280-018-3525-8. Epub 2018 Feb 1.

PMID:
29387964
15.

Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark.

Stoltze U, Skytte AB, Roed H, Hasle H, Ejlertsen B, Overeem Hansen TV, Schmiegelow K, Gerdes AM, Wadt K.

PLoS One. 2018 Jan 11;13(1):e0190050. doi: 10.1371/journal.pone.0190050. eCollection 2018.

16.

Five percent of healthy newborns have an ETV6-RUNX1 fusion as revealed by DNA-based GIPFEL screening.

Schäfer D, Olsen M, Lähnemann D, Stanulla M, Slany R, Schmiegelow K, Borkhardt A, Fischer U.

Blood. 2018 Feb 15;131(7):821-826. doi: 10.1182/blood-2017-09-808402. Epub 2018 Jan 8. No abstract available.

17.

A Role for Thiopurine Metabolites in the Synergism Between Thiopurines and Infliximab in Inflammatory Bowel Disease.

Mogensen DV, Brynskov J, Ainsworth MA, Nersting J, Schmiegelow K, Steenholdt C.

J Crohns Colitis. 2018 Feb 28;12(3):298-305. doi: 10.1093/ecco-jcc/jjx149.

PMID:
29145599
18.

Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance.

Ramsey LB, Balis FM, O'Brien MM, Schmiegelow K, Pauley JL, Bleyer A, Widemann BC, Askenazi D, Bergeron S, Shirali A, Schwartz S, Vinks AA, Heldrup J.

Oncologist. 2018 Jan;23(1):52-61. doi: 10.1634/theoncologist.2017-0243. Epub 2017 Oct 27.

19.

Individualized 6-mercaptopurine increments in consolidation treatment of childhood acute lymphoblastic leukemia: A NOPHO randomized controlled trial.

Tulstrup M, Frandsen TL, Abrahamsson J, Lund B, Vettenranta K, Jonsson OG, Marquart HVH, Albertsen BK, Heyman M, Schmiegelow K.

Eur J Haematol. 2018 Jan;100(1):53-60. doi: 10.1111/ejh.12979. Epub 2017 Nov 9.

PMID:
28983968
20.

Maternal diabetes and risk of childhood acute lymphoblastic leukaemia in the offspring.

Søegaard SH, Rostgaard K, Kamper-Jørgensen M, Schmiegelow K, Hjalgrim H.

Br J Cancer. 2018 Jan;118(1):117-120. doi: 10.1038/bjc.2017.351. Epub 2017 Oct 3.

PMID:
28972964
21.

Survival from tumours of the central nervous system in Danish children: Is survival related to family circumstances?

Erdmann F, Winther JF, Dalton SO, Zeeb H, Krøyer A, Bautz A, Schmiegelow K, Schüz J.

Int J Cancer. 2018 Feb 15;142(4):671-680. doi: 10.1002/ijc.31082. Epub 2017 Oct 16.

PMID:
28971474
22.

Youth friendly communication in a transition clinic aimed at adolescents with chronic illness.

Hanghøj S, Boisen KA, Schmiegelow K, Hølge-Hazelton B.

Int J Adolesc Med Health. 2017 Aug 29. pii: /j/ijamh.ahead-of-print/ijamh-2017-0083/ijamh-2017-0083.xml. doi: 10.1515/ijamh-2017-0083. [Epub ahead of print]

PMID:
28850549
23.

Results of NOPHO ALL2008 treatment for patients aged 1-45 years with acute lymphoblastic leukemia.

Toft N, Birgens H, Abrahamsson J, Griškevičius L, Hallböök H, Heyman M, Klausen TW, Jónsson ÓG, Palk K, Pruunsild K, Quist-Paulsen P, Vaitkeviciene G, Vettenranta K, Åsberg A, Frandsen TL, Marquart HV, Madsen HO, Norén-Nyström U, Schmiegelow K.

Leukemia. 2018 Mar;32(3):606-615. doi: 10.1038/leu.2017.265. Epub 2017 Aug 18.

PMID:
28819280
24.

A qualitative study of decision-making on Phase III randomized clinical trial participation in paediatric oncology: Adolescents' and parents' perspectives and preferences.

Ingersgaard MV, Tulstrup M, Schmiegelow K, Larsen HB.

J Adv Nurs. 2018 Jan;74(1):110-118. doi: 10.1111/jan.13407. Epub 2017 Sep 10.

PMID:
28771784
25.

Cardiorespiratory fitness and physical function in children with cancer from diagnosis throughout treatment.

Thorsteinsson T, Larsen HB, Schmiegelow K, Thing LF, Krustrup P, Pedersen MT, Christensen KB, Mogensen PR, Helms AS, Andersen LB.

BMJ Open Sport Exerc Med. 2017 May 12;3(1):e000179. doi: 10.1136/bmjsem-2016-000179. eCollection 2017.

26.

Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study.

Wolthers BO, Frandsen TL, Baruchel A, Attarbaschi A, Barzilai S, Colombini A, Escherich G, Grell K, Inaba H, Kovacs G, Liang DC, Mateos M, Mondelaers V, Möricke A, Ociepa T, Samarasinghe S, Silverman LB, van der Sluis IM, Stanulla M, Vrooman LM, Yano M, Zapotocka E, Schmiegelow K; Ponte di Legno Toxicity Working Group.

Lancet Oncol. 2017 Sep;18(9):1238-1248. doi: 10.1016/S1470-2045(17)30424-2. Epub 2017 Jul 20.

PMID:
28736188
27.

Prolonged first-line PEG-asparaginase treatment in pediatric acute lymphoblastic leukemia in the NOPHO ALL2008 protocol-Pharmacokinetics and antibody formation.

Tram Henriksen L, Gottschalk Højfeldt S, Schmiegelow K, Frandsen TL, Skov Wehner P, Schrøder H, Klug Albertsen B; Nordic Society of Pediatric Hematology and Oncology, NOPHO Group.

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26686. Epub 2017 Jun 29.

PMID:
28660740
28.

EEG with extreme delta brush in young female with methotrexate neurotoxicity supports NMDA receptor involvement.

Schmidt LS, Kjær TW, Schmiegelow K, Born AP.

Eur J Paediatr Neurol. 2017 Sep;21(5):795-797. doi: 10.1016/j.ejpn.2017.05.008. Epub 2017 Jun 15.

PMID:
28655493
29.

Liposomal Cytarabine Induces Less Neurocognitive Dysfunction Than Intrathecal Methotrexate in an Animal Model.

Thomsen AM, Gulinello ME, Wen J, Schmiegelow K, Cole PD.

J Pediatr Hematol Oncol. 2018 Mar;40(2):e91-e96. doi: 10.1097/MPH.0000000000000888.

PMID:
28654460
30.

Cerebellar mutism syndrome in children with brain tumours of the posterior fossa.

Wibroe M, Cappelen J, Castor C, Clausen N, Grillner P, Gudrunardottir T, Gupta R, Gustavsson B, Heyman M, Holm S, Karppinen A, Klausen C, Lönnqvist T, Mathiasen R, Nilsson P, Nysom K, Persson K, Rask O, Schmiegelow K, Sehested A, Thomassen H, Tonning-Olsson I, Zetterqvist B, Juhler M.

BMC Cancer. 2017 Jun 21;17(1):439. doi: 10.1186/s12885-017-3416-0.

31.

Do cytogenetics of acute lymphoblastic leukaemia blasts affect required duration and intensity of maintenance therapy? - Authors' reply.

Schmiegelow K, Nielsen SN, Grell K.

Lancet Oncol. 2017 Jun;18(6):e292. doi: 10.1016/S1470-2045(17)30348-0. No abstract available.

PMID:
28593847
32.

Early presentation of osteonecrosis in acute lymphoblastic leukemia: Two children from the Nordic and Baltic cohort.

Mogensen SS, Harila-Saari A, Frandsen TL, Lähteenmäki P, Castor A, Kohonen I, Schmiegelow K, Mäkitie O.

Pediatr Blood Cancer. 2017 Nov;64(11). doi: 10.1002/pbc.26624. Epub 2017 May 18.

PMID:
28521072
33.

Children with low-risk acute lymphoblastic leukemia are at highest risk of second cancers.

Nielsen SN, Eriksson F, Rosthoej S, Andersen MK, Forestier E, Hasle H, Hjalgrim LL, Aasberg A, Abrahamsson J, Heyman M, Jónsson ÓG, Pruunsild K, Vaitkeviciené GE, Vettenranta K, Schmiegelow K.

Pediatr Blood Cancer. 2017 Oct;64(10). doi: 10.1002/pbc.26518. Epub 2017 May 13.

PMID:
28500740
34.

The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia.

Moriyama T, Nishii R, Lin TN, Kihira K, Toyoda H, Jacob N, Kato M, Koh K, Inaba H, Manabe A, Schmiegelow K, Yang JJ, Hori H.

Pharmacogenet Genomics. 2017 Jun;27(6):236-239. doi: 10.1097/FPC.0000000000000282.

35.

Childhood vaccinations and risk of acute lymphoblastic leukaemia in children.

Søegaard SH, Rostgaard K, Schmiegelow K, Kamper-Jørgensen M, Hargreave M, Hjalgrim H, Hviid A.

Int J Epidemiol. 2017 Jun 1;46(3):905-913. doi: 10.1093/ije/dyx052.

PMID:
28431124
36.

Hepatic sinusoidal obstruction syndrome during maintenance therapy of childhood acute lymphoblastic leukemia is associated with continuous asparaginase therapy and mercaptopurine metabolites.

Toksvang LN, De Pietri S, Nielsen SN, Nersting J, Albertsen BK, Wehner PS, Rosthøj S, Lähteenmäki PM, Nilsson D, Nystad TA, Grell K, Frandsen TL, Schmiegelow K.

Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26519. Epub 2017 Apr 19. Erratum in: Pediatr Blood Cancer. 2018 Jan;65(1):.

PMID:
28423235
37.

Non-infectious chemotherapy-associated acute toxicities during childhood acute lymphoblastic leukemia therapy.

Schmiegelow K, Müller K, Mogensen SS, Mogensen PR, Wolthers BO, Stoltze UK, Tuckuviene R, Frandsen T.

F1000Res. 2017 Apr 7;6:444. doi: 10.12688/f1000research.10768.1. eCollection 2017. Review.

38.

DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial.

Nielsen SN, Grell K, Nersting J, Abrahamsson J, Lund B, Kanerva J, Jónsson ÓG, Vaitkeviciene G, Pruunsild K, Hjalgrim LL, Schmiegelow K.

Lancet Oncol. 2017 Apr;18(4):515-524. doi: 10.1016/S1470-2045(17)30154-7. Epub 2017 Mar 1.

PMID:
28258828
39.

Hyperlipidemia is a risk factor for osteonecrosis in children and young adults with acute lymphoblastic leukemia.

Mogensen SS, Schmiegelow K, Grell K, Albertsen BK, Wehner PS, Kampmann P, Frandsen TL.

Haematologica. 2017 May;102(5):e175-e178. doi: 10.3324/haematol.2016.160507. Epub 2017 Feb 16. No abstract available.

40.

FAMily-Oriented Support (FAMOS): development and feasibility of a psychosocial intervention for families of childhood cancer survivors.

Salem H, Johansen C, Schmiegelow K, Winther JF, Wehner PS, Hasle H, Rosthøj S, Kazak AE, E Bidstrup P.

Acta Oncol. 2017 Feb;56(2):367-374. doi: 10.1080/0284186X.2016.1269194. Epub 2017 Jan 12.

PMID:
28080169
41.

Hepatotoxicity During Maintenance Therapy and Prognosis in Children With Acute Lymphoblastic Leukemia.

Ebbesen MS, Nygaard U, Rosthøj S, Sørensen D, Nersting J, Vettenranta K, Wesenberg F, Kristinsson J, Harila-Saari A, Schmiegelow K.

J Pediatr Hematol Oncol. 2017 Apr;39(3):161-166. doi: 10.1097/MPH.0000000000000733.

PMID:
28060115
42.

Delayed elimination of high-dose methotrexate and use of carboxypeptidase G2 in pediatric patients during treatment for acute lymphoblastic leukemia.

Svahn T, Mellgren K, Harila-Saari A, Åsberg A, Kanerva J, Jónsson Ó, Vaitkeviciene G, Stamm Mikkelssen T, Schmiegelow K, Heldrup J.

Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26395. Epub 2016 Dec 14.

PMID:
27966809
43.

Measures of 6-mercaptopurine and methotrexate maintenance therapy intensity in childhood acute lymphoblastic leukemia.

Nielsen SN, Grell K, Nersting J, Frandsen TL, Hjalgrim LL, Schmiegelow K.

Cancer Chemother Pharmacol. 2016 Nov;78(5):983-994. Epub 2016 Sep 6.

PMID:
27600880
44.

Efficacy and Toxicity of Intrathecal Liposomal Cytarabine in First-line Therapy of Childhood Acute Lymphoblastic Leukemia.

Levinsen M, Harila-Saari A, Grell K, Jonsson OG, Taskinen M, Abrahamsson J, Vettenranta K, Åsberg A, Risteli J, Heldrup J, Schmiegelow K.

J Pediatr Hematol Oncol. 2016 Nov;38(8):602-609.

PMID:
27571129
45.

Maintenance therapy of childhood acute lymphoblastic leukemia revisited-Should drug doses be adjusted by white blood cell, neutrophil, or lymphocyte counts?

Schmiegelow K, Nersting J, Nielsen SN, Heyman M, Wesenberg F, Kristinsson J, Vettenranta K, Schrøeder H, Weinshilboum R, Jensen KL, Grell K, Rosthoej S.

Pediatr Blood Cancer. 2016 Dec;63(12):2104-2111. doi: 10.1002/pbc.26139. Epub 2016 Jul 22.

PMID:
27447547
46.

Varicella Vaccination of Children With Leukemia Without Interruption of Maintenance Therapy: A Danish Experience.

Smedegaard LM, Poulsen A, Kristensen IA, Rosthøj S, Schmiegelow K, Nygaard U.

Pediatr Infect Dis J. 2016 Nov;35(11):e348-e352.

PMID:
27753768
47.

The effect of central nervous system involvement and irradiation in childhood acute lymphoblastic leukemia: Lessons from the NOPHO ALL-92 and ALL-2000 protocols.

Taskinen M, Oskarsson T, Levinsen M, Bottai M, Hellebostad M, Jonsson OG, Lähteenmäki P, Schmiegelow K, Heyman M.

Pediatr Blood Cancer. 2017 Feb;64(2):242-249. doi: 10.1002/pbc.26191. Epub 2016 Oct 17.

PMID:
27748030
48.

Feasibility of a transition intervention aimed at adolescents with chronic illness.

Hanghøj S, Boisen KA, Schmiegelow K, Hølge-Hazelton B.

Int J Adolesc Med Health. 2016 Oct 14;30(3). pii: /j/ijamh.2018.30.issue-3/ijamh-2016-0047/ijamh-2016-0047.xml. doi: 10.1515/ijamh-2016-0047.

PMID:
27740919
49.

Chemotherapeutic treatment reduces circulating levels of surfactant protein-D in children with acute lymphoblastic leukemia.

Rathe M, Sorensen GL, Wehner PS, Holmskov U, Sangild PT, Schmiegelow K, Müller K, Husby S.

Pediatr Blood Cancer. 2017 Mar;64(3). doi: 10.1002/pbc.26253. Epub 2016 Sep 26.

PMID:
27667327
50.

Being Young and Getting Cancer: Development of a Questionnaire Reflecting the Needs and Experiences of Adolescents and Young Adults with Cancer.

Sperling CD, Petersen GS, Hølge-Hazelton B, Graugaard C, Winther JF, Gudmundsdottir T, Ahrensberg J, Schmiegelow K, Boisen KA, Olsen PR, Heerdegen AC, Sonnenschein ES, Knudsen JL.

J Adolesc Young Adult Oncol. 2017 Mar;6(1):171-177. doi: 10.1089/jayao.2015.0063. Epub 2016 Sep 21.

PMID:
27654508
51.

Asparaginase-associated pancreatitis is not predicted by hypertriglyceridemia or pancreatic enzyme levels in children with acute lymphoblastic leukemia.

Raja RA, Schmiegelow K, Sørensen DN, Frandsen TL.

Pediatr Blood Cancer. 2017 Jan;64(1):32-38. doi: 10.1002/pbc.26183. Epub 2016 Aug 24.

PMID:
27555294
52.

Role of neuroimaging in children with acute lymphoblastic leukemia and central nervous system involvement at diagnosis.

Ranta S, Palomäki M, Levinsen M, Taskinen M, Abrahamsson J, Mellgren K, Niinimäki R, Schmiegelow K, Heyman M, Harila-Saari A; Nordic Society of Pediatric Hematology and Oncology (NOPHO).

Pediatr Blood Cancer. 2017 Jan;64(1):64-70. doi: 10.1002/pbc.26182. Epub 2016 Aug 24.

PMID:
27555087
53.

Asparaginase-associated pancreatitis: a study on phenotype and genotype in the NOPHO ALL2008 protocol.

Wolthers BO, Frandsen TL, Abrahamsson J, Albertsen BK, Helt LR, Heyman M, Jónsson ÓG, Kõrgvee LT, Lund B, Raja RA, Rasmussen KK, Taskinen M, Tulstrup M, Vaitkevičienė GE, Yadav R, Gupta R, Schmiegelow K.

Leukemia. 2017 Feb;31(2):325-332. doi: 10.1038/leu.2016.203. Epub 2016 Jul 25.

PMID:
27451978
54.

Leukemic blasts are present at low levels in spinal fluid in one-third of childhood acute lymphoblastic leukemia cases.

Levinsen M, Marquart HV, Groth-Pedersen L, Abrahamsson J, Albertsen BK, Andersen MK, Frandsen TL, Harila-Saari A, Pronk C, Ulvmoen A, Vaitkevičienė G, Lähteenmäki PM, Niinimäki R, Taskinen M, Jeppesen M, Schmiegelow K; Nordic Society of Pediatric Hematology and Oncology (NOPHO).

Pediatr Blood Cancer. 2016 Nov;63(11):1935-42. doi: 10.1002/pbc.26128. Epub 2016 Jul 22.

PMID:
27447373
55.

Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus.

Schmiegelow K, Attarbaschi A, Barzilai S, Escherich G, Frandsen TL, Halsey C, Hough R, Jeha S, Kato M, Liang DC, Mikkelsen TS, Möricke A, Niinimäki R, Piette C, Putti MC, Raetz E, Silverman LB, Skinner R, Tuckuviene R, van der Sluis I, Zapotocka E; Ponte di Legno toxicity working group.

Lancet Oncol. 2016 Jun;17(6):e231-e239. doi: 10.1016/S1470-2045(16)30035-3. Review.

56.

Extremely low-frequency magnetic fields and risk of childhood leukemia: A risk assessment by the ARIMMORA consortium.

Schüz J, Dasenbrock C, Ravazzani P, Röösli M, Schär P, Bounds PL, Erdmann F, Borkhardt A, Cobaleda C, Fedrowitz M, Hamnerius Y, Sanchez-Garcia I, Seger R, Schmiegelow K, Ziegelberger G, Capstick M, Manser M, Müller M, Schmid CD, Schürmann D, Struchen B, Kuster N.

Bioelectromagnetics. 2016 Mar 15. doi: 10.1002/bem.21963. [Epub ahead of print]

PMID:
26991812
57.

A Photo Elicitation Study on Chronically Ill Adolescents' Identity Constructions During Transition.

Hanghøj S, Boisen KA, Schmiegelow K, Hølge-Hazelton B.

Glob Qual Nurs Res. 2016 Mar 8;3:2333393616631678. doi: 10.1177/2333393616631678. eCollection 2016 Jan-Dec.

58.

Survival From Childhood Hematological Malignancies in Denmark: Is Survival Related to Family Characteristics?

Erdmann F, Winther JF, Dalton SO, Lightfoot T, Zeeb H, Simony SB, Deltour I, Ferro G, Bautz A, Schmiegelow K, Schüz J.

Pediatr Blood Cancer. 2016 Jun;63(6):1096-104. doi: 10.1002/pbc.25950. Epub 2016 Mar 3.

PMID:
26937602
59.

Effect of socioeconomic position on survival after childhood cancer in Denmark.

Simony SB, Lund LW, Erdmann F, Andersen KK, Winther JF, Schüz J, Johansen C, Schmiegelow K, Dalton SO.

Acta Oncol. 2016 Jun;55(6):742-50. doi: 10.3109/0284186X.2016.1144933. Epub 2016 Mar 3.

PMID:
26935257
60.

DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia.

Borssén M, Haider Z, Landfors M, Norén-Nyström U, Schmiegelow K, Åsberg AE, Kanerva J, Madsen HO, Marquart H, Heyman M, Hultdin M, Roos G, Forestier E, Degerman S.

Pediatr Blood Cancer. 2016 Jul;63(7):1185-92. doi: 10.1002/pbc.25958. Epub 2016 Feb 29.

PMID:
26928953
61.

NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.

Moriyama T, Nishii R, Perez-Andreu V, Yang W, Klussmann FA, Zhao X, Lin TN, Hoshitsuki K, Nersting J, Kihira K, Hofmann U, Komada Y, Kato M, McCorkle R, Li L, Koh K, Najera CR, Kham SK, Isobe T, Chen Z, Chiew EK, Bhojwani D, Jeffries C, Lu Y, Schwab M, Inaba H, Pui CH, Relling MV, Manabe A, Hori H, Schmiegelow K, Yeoh AE, Evans WE, Yang JJ.

Nat Genet. 2016 Apr;48(4):367-73. doi: 10.1038/ng.3508. Epub 2016 Feb 15.

62.

Treatment-related toxicities in children with acute lymphoblastic leukaemia predisposition syndromes.

Schmiegelow K.

Eur J Med Genet. 2016 Dec;59(12):654-660. doi: 10.1016/j.ejmg.2016.02.006. Epub 2016 Feb 11. Review.

PMID:
26876989
63.

In sickness and in health: classmates are highly motivated to provide in-hospital support during childhood cancer therapy.

Lindgren LH, Schmiegelow K, Helms AS, Thorsteinsson T, Larsen HB.

Psychooncology. 2017 Jan;26(1):37-43. doi: 10.1002/pon.4094. Epub 2016 Feb 12.

PMID:
26872002
64.

Parents' and Adolescents' Preferences for Intensified or Reduced Treatment in Randomized Lymphoblastic Leukemia Trials.

Tulstrup M, Larsen HB, Castor A, Rossel P, Grell K, Heyman M, Abrahamsson J, Söderhäll S, Åsberg A, Jonsson OG, Vettenranta K, Frandsen TL, Albertsen BK, Schmiegelow K; Nordic Society of Paediatric Haematology, and Oncology (NOPHO).

Pediatr Blood Cancer. 2016 May;63(5):865-71. doi: 10.1002/pbc.25887. Epub 2015 Dec 31.

PMID:
26717887
65.

Classification of treatment-related mortality in children with cancer: a systematic assessment.

Alexander S, Pole JD, Gibson P, Lee M, Hesser T, Chi SN, Dvorak CC, Fisher B, Hasle H, Kanerva J, Möricke A, Phillips B, Raetz E, Rodriguez-Galindo C, Samarasinghe S, Schmiegelow K, Tissing W, Lehrnbecher T, Sung L; International Pediatric Oncology Mortality Classification Group.

Lancet Oncol. 2015 Dec;16(16):e604-10. doi: 10.1016/S1470-2045(15)00197-7. Review.

PMID:
26678213
66.

Evaluation of a pediatric liquid formulation to improve 6-mercaptopurine therapy in children.

Tiphaine Ade B, Hjalgrim LL, Nersting J, Breitkreutz J, Nelken B, Schrappe M, Stanulla M, Thomas C, Bertrand Y, Leverger G, Baruchel A, Schmiegelow K, Jacqz-Aigrain E.

Eur J Pharm Sci. 2016 Feb 15;83:1-7. doi: 10.1016/j.ejps.2015.12.002. Epub 2015 Dec 2.

PMID:
26657824
67.

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.

Pui CH, Yang JJ, Hunger SP, Pieters R, Schrappe M, Biondi A, Vora A, Baruchel A, Silverman LB, Schmiegelow K, Escherich G, Horibe K, Benoit YC, Izraeli S, Yeoh AE, Liang DC, Downing JR, Evans WE, Relling MV, Mullighan CG.

J Clin Oncol. 2015 Sep 20;33(27):2938-48. doi: 10.1200/JCO.2014.59.1636. Epub 2015 Aug 24. Review.

68.

Serial Ultrasound Monitoring for Early Recognition of Asparaginase Associated Pancreatitis in Children With Acute Lymphoblastic Leukemia.

Raja RA, Schmiegelow K, Henriksen BM, Leth Frandsen T.

Pediatr Hematol Oncol. 2015;32(7):474-81. doi: 10.3109/08880018.2015.1055868. Epub 2015 Aug 13.

PMID:
26270775
69.

Adipokines in umbilical cord blood from children born large for gestational age.

Lausten-Thomsen U, Christiansen M, Hedley PL, Holm JC, Schmiegelow K.

J Pediatr Endocrinol Metab. 2016 Jan;29(1):33-7. doi: 10.1515/jpem-2014-0502.

70.

Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children.

Xu H, Zhang H, Yang W, Yadav R, Morrison AC, Qian M, Devidas M, Liu Y, Perez-Andreu V, Zhao X, Gastier-Foster JM, Lupo PJ, Neale G, Raetz E, Larsen E, Bowman WP, Carroll WL, Winick N, Williams R, Hansen T, Holm JC, Mardis E, Fulton R, Pui CH, Zhang J, Mullighan CG, Evans WE, Hunger SP, Gupta R, Schmiegelow K, Loh ML, Relling MV, Yang JJ.

Nat Commun. 2015 Jun 24;6:7553. doi: 10.1038/ncomms8553.

71.

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.

Wojtuszkiewicz A, Peters GJ, van Woerden NL, Dubbelman B, Escherich G, Schmiegelow K, Sonneveld E, Pieters R, van de Ven PM, Jansen G, Assaraf YG, Kaspers GJ, Cloos J.

J Hematol Oncol. 2015 May 29;8:61. doi: 10.1186/s13045-015-0158-9.

72.

Peripherally applied opioids for postoperative pain: evidence of an analgesic effect? A systematic review and meta-analysis.

Nielsen BN, Henneberg SW, Schmiegelow K, Friis SM, Rømsing J.

Acta Anaesthesiol Scand. 2015 Aug;59(7):830-45. doi: 10.1111/aas.12529. Epub 2015 Apr 24. Review.

PMID:
25911979
73.

Toxicity profile and treatment delays in NOPHO ALL2008-comparing adults and children with Philadelphia chromosome-negative acute lymphoblastic leukemia.

Toft N, Birgens H, Abrahamsson J, Griškevičius L, Hallböök H, Heyman M, Klausen TW, Jónsson ÓG, Palk K, Pruunsild K, Quist-Paulsen P, Vaitkeviciene G, Vettenranta K, Asberg A, Helt LR, Frandsen T, Schmiegelow K.

Eur J Haematol. 2016 Feb;96(2):160-9. doi: 10.1111/ejh.12562. Epub 2015 Apr 24.

PMID:
25867866
74.

Mercaptopurine metabolite levels are predictors of bone marrow toxicity following high-dose methotrexate therapy of childhood acute lymphoblastic leukaemia.

Vang SI, Schmiegelow K, Frandsen T, Rosthøj S, Nersting J.

Cancer Chemother Pharmacol. 2015 May;75(5):1089-93. doi: 10.1007/s00280-015-2717-8. Epub 2015 Mar 19.

PMID:
25788208
75.

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia.

Nordlund J, Bäcklin CL, Zachariadis V, Cavelier L, Dahlberg J, Öfverholm I, Barbany G, Nordgren A, Övernäs E, Abrahamsson J, Flaegstad T, Heyman MM, Jónsson ÓG, Kanerva J, Larsson R, Palle J, Schmiegelow K, Gustafsson MG, Lönnerholm G, Forestier E, Syvänen AC.

Clin Epigenetics. 2015 Feb 17;7:11. doi: 10.1186/s13148-014-0039-z. eCollection 2015.

76.

Increased risk of antidepressant use in childhood cancer survivors: a Danish population-based cohort study.

Lund LW, Winther JF, Cederkvist L, Andersen KK, Dalton SO, Appel CW, Rechnitzer C, Schmiegelow K, Johansen C.

Eur J Cancer. 2015 Mar;51(5):675-84. doi: 10.1016/j.ejca.2015.01.001. Epub 2015 Feb 9.

PMID:
25677304
77.

Archival bone marrow samples: suitable for multiple biomarker analysis.

Lund B, Najmi LA, Wesolowska-Andersen A, Landsem VM, Rasmussen KK, Borst L, Gupta R, Schmiegelow K, Klungland H.

Appl Immunohistochem Mol Morphol. 2015 Jan;23(1):71-7. doi: 10.1097/PDM.0000000000000032.

PMID:
25621358
78.

Polymorphisms in the ABCB1 gene and effect on outcome and toxicity in childhood acute lymphoblastic leukemia.

Gregers J, Gréen H, Christensen IJ, Dalhoff K, Schroeder H, Carlsen N, Rosthoej S, Lausen B, Schmiegelow K, Peterson C.

Pharmacogenomics J. 2015 Aug;15(4):372-9. doi: 10.1038/tpj.2014.81. Epub 2015 Jan 13.

79.

A novel chemosensitivity profiling platform for small acute lymphoblastic leukemia cell populations.

Groth-Pedersen L, Chen YH, Faber M, Valentin R, Albertsen BK, Wehner PS, Rosthøj S, Frandsen TL, Marquart HV, Schmiegelow K.

Leuk Lymphoma. 2015 Jul;56(7):2208-11. doi: 10.3109/10428194.2014.996851. Epub 2015 Jan 21. No abstract available.

PMID:
25530346
80.

PEG-asparaginase allergy in children with acute lymphoblastic leukemia in the NOPHO ALL2008 protocol.

Henriksen LT, Harila-Saari A, Ruud E, Abrahamsson J, Pruunsild K, Vaitkeviciene G, Jónsson ÓG, Schmiegelow K, Heyman M, Schrøder H, Albertsen BK; Nordic Society of Paediatric Haematology and Oncology (NOPHO) group.

Pediatr Blood Cancer. 2015 Mar;62(3):427-33. doi: 10.1002/pbc.25319. Epub 2014 Nov 21.

PMID:
25418987
81.

Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity.

Levinsen M, Rosthøj S, Nygaard U, Heldrup J, Harila-Saari A, Jonsson OG, Bechensteen AG, Abrahamsson J, Lausen B, Frandsen TL, Weinshilboum RM, Schmiegelow K.

Cancer Chemother Pharmacol. 2015 Jan;75(1):59-66. doi: 10.1007/s00280-014-2613-7. Epub 2014 Oct 28.

82.

Facilitation of school re-entry and peer acceptance of children with cancer: a review and meta-analysis of intervention studies.

Helms AS, Schmiegelow K, Brok J, Johansen C, Thorsteinsson T, Simovska V, Larsen HB.

Eur J Cancer Care (Engl). 2016 Jan;25(1):170-9. doi: 10.1111/ecc.12230. Epub 2014 Sep 10. Review.

PMID:
25204197
83.

Pharmacokinetics of 6-Thioguanine and 6-Mercaptopurine Combination Maintenance Therapy of Childhood ALL: Hypothesis and Case Report.

Nielsen SN, Frandsen TL, Nersting J, Hjalgrim LL, Schmiegelow K.

J Pediatr Hematol Oncol. 2015 Apr;37(3):e206-9. doi: 10.1097/MPH.0000000000000246.

PMID:
25171455
84.

Cure rates of childhood acute lymphoblastic leukemia in Lithuania and the benefit of joining international treatment protocol.

Vaitkevičienė G, Matuzevičienė R, Stoškus M, Žvirblis T, Ragelienė L, Schmiegelow K.

Medicina (Kaunas). 2014;50(1):28-36. doi: 10.1016/j.medici.2014.05.005. Epub 2014 Jun 6.

85.

Treatment-related myelodysplastic syndrome in a child with acute myeloid leukemia and TPMT heterozygosity.

Stensman LM, Kjeldsen E, Nersting J, Schmiegelow K, Hasle H.

J Pediatr Hematol Oncol. 2015 May;37(4):e242-4. doi: 10.1097/MPH.0000000000000211.

PMID:
25000470
86.

Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients.

Wesołowska-Andersen A, Borst L, Dalgaard MD, Yadav R, Rasmussen KK, Wehner PS, Rasmussen M, Ørntoft TF, Nordentoft I, Koehler R, Bartram CR, Schrappe M, Sicheritz-Ponten T, Gautier L, Marquart H, Madsen HO, Brunak S, Stanulla M, Gupta R, Schmiegelow K.

Leukemia. 2015 Feb;29(2):297-303. doi: 10.1038/leu.2014.205. Epub 2014 Jul 3.

87.

How safe is a standard-risk child with ALL?

Winther JF, Schmiegelow K.

Lancet Oncol. 2014 Jul;15(8):782-3. doi: 10.1016/S1470-2045(14)70294-3. Epub 2014 Jun 19. No abstract available.

PMID:
24954780
88.

Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction.

Schmiegelow K, Nielsen SN, Frandsen TL, Nersting J.

J Pediatr Hematol Oncol. 2014 Oct;36(7):503-17. doi: 10.1097/MPH.0000000000000206. Review.

89.

False positivity of ETV6/RUNX1 detected by FISH in healthy newborns and adults.

Kusk MS, Lausten-Thomsen U, Andersen MK, Olsen M, Hjalgrim H, Schmiegelow K.

Pediatr Blood Cancer. 2014 Sep;61(9):1704-6. doi: 10.1002/pbc.25050. Epub 2014 Apr 17.

PMID:
24740533
90.

T-cell ALL in ataxia telangiectasia cured with only 7 weeks of anti-leukemic therapy.

Hersby DS, Sehested A, Kristensen K, Schmiegelow K.

J Pediatr Hematol Oncol. 2015 Mar;37(2):154-5. doi: 10.1097/MPH.0000000000000151.

PMID:
24663073
91.

Clinical features and early treatment response of central nervous system involvement in childhood acute lymphoblastic leukemia.

Levinsen M, Taskinen M, Abrahamsson J, Forestier E, Frandsen TL, Harila-Saari A, Heyman M, Jonsson OG, Lähteenmäki PM, Lausen B, Vaitkevičienė G, Asberg A, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

Pediatr Blood Cancer. 2014 Aug;61(8):1416-21. doi: 10.1002/pbc.24981. Epub 2014 Feb 12.

PMID:
24623619
92.

Inflammatory markers in umbilical cord blood from small-for-gestational-age newborns.

Lausten-Thomsen U, Olsen M, Greisen G, Schmiegelow K.

Fetal Pediatr Pathol. 2014 Apr;33(2):114-8. doi: 10.3109/15513815.2013.879239. Epub 2014 Jan 29.

PMID:
24476425
93.

Asparaginase-associated pancreatitis in children with acute lymphoblastic leukaemia in the NOPHO ALL2008 protocol.

Raja RA, Schmiegelow K, Albertsen BK, Prunsild K, Zeller B, Vaitkeviciene G, Abrahamsson J, Heyman M, Taskinen M, Harila-Saari A, Kanerva J, Frandsen TL; Nordic Society of Paediatric Haematology and Oncology (NOPHO) group.

Br J Haematol. 2014 Apr;165(1):126-33. doi: 10.1111/bjh.12733. Epub 2014 Jan 15.

PMID:
24428625
94.

Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: influence on cure rates and risk of second cancer.

Levinsen M, Rotevatn EØ, Rosthøj S, Nersting J, Abrahamsson J, Appell ML, Bergan S, Bechensteen AG, Harila-Saari A, Heyman M, Jonsson OG, Maxild JB, Niemi M, Söderhäll S, Schmiegelow K; Nordic Society of Paediatric Haematology, Oncology.

Pediatr Blood Cancer. 2014 May;61(5):797-802. doi: 10.1002/pbc.24921. Epub 2014 Jan 3.

PMID:
24395436
95.

Host genome variations and risk of infections during induction treatment for childhood acute lymphoblastic leukaemia.

Lund B, Wesolowska-Andersen A, Lausen B, Borst L, Rasmussen KK, Müller K, Klungland H, Gupta R, Schmiegelow K.

Eur J Haematol. 2014 Apr;92(4):321-30. doi: 10.1111/ejh.12243. Epub 2014 Jan 28.

PMID:
24330153
96.

The circadian schedule for childhood acute lymphoblastic leukemia maintenance therapy does not influence event-free survival in the NOPHO ALL92 protocol.

Clemmensen KK, Christensen RH, Shabaneh DN, Harila-Saari A, Heyman M, Jonsson OG, Wesenberg F, Rosthøj S, Schmiegelow K; Nordic Society of Pediatric Hematology, Oncology (NOPHO).

Pediatr Blood Cancer. 2014 Apr;61(4):653-8. doi: 10.1002/pbc.24867. Epub 2013 Nov 22.

PMID:
24265159
97.

Complying with the European Clinical Trials directive while surviving the administrative pressure - an alternative approach to toxicity registration in a cancer trial.

Frandsen TL, Heyman M, Abrahamsson J, Vettenranta K, Åsberg A, Vaitkeviciene G, Pruunsild K, Toft N, Birgens H, Hallböök H, Quist-Paulsen P, Griškevičius L, Helt L, Hansen BV, Schmiegelow K.

Eur J Cancer. 2014 Jan;50(2):251-9. doi: 10.1016/j.ejca.2013.09.027. Epub 2013 Nov 11.

PMID:
24231337
98.

Study protocol: Rehabilitation including Social and Physical activity and Education in Children and Teenagers with Cancer (RESPECT).

Thorsteinsson T, Helms AS, Adamsen L, Andersen LB, Andersen KV, Christensen KB, Hasle H, Heilmann C, Hejgaard N, Johansen C, Madsen M, Madsen SA, Simovska V, Strange B, Thing LF, Wehner PS, Schmiegelow K, Larsen HB.

BMC Cancer. 2013 Nov 14;13:544. doi: 10.1186/1471-2407-13-544.

99.

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group.

Buitenkamp TD, Izraeli S, Zimmermann M, Forestier E, Heerema NA, van den Heuvel-Eibrink MM, Pieters R, Korbijn CM, Silverman LB, Schmiegelow K, Liang DC, Horibe K, Arico M, Biondi A, Basso G, Rabin KR, Schrappe M, Cario G, Mann G, Morak M, Panzer-Grümayer R, Mondelaers V, Lammens T, Cavé H, Stark B, Ganmore I, Moorman AV, Vora A, Hunger SP, Pui CH, Mullighan CG, Manabe A, Escherich G, Kowalczyk JR, Whitlock JA, Zwaan CM.

Blood. 2014 Jan 2;123(1):70-7. doi: 10.1182/blood-2013-06-509463. Epub 2013 Nov 12.

100.

Intranasal sufentanil/ketamine analgesia in children.

Nielsen BN, Friis SM, Rømsing J, Schmiegelow K, Anderson BJ, Ferreirós N, Labocha S, Henneberg SW.

Paediatr Anaesth. 2014 Feb;24(2):170-80. doi: 10.1111/pan.12268. Epub 2013 Oct 1.

PMID:
24118506
101.

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia.

Nordlund J, Bäcklin CL, Wahlberg P, Busche S, Berglund EC, Eloranta ML, Flaegstad T, Forestier E, Frost BM, Harila-Saari A, Heyman M, Jónsson OG, Larsson R, Palle J, Rönnblom L, Schmiegelow K, Sinnett D, Söderhäll S, Pastinen T, Gustafsson MG, Lönnerholm G, Syvänen AC.

Genome Biol. 2013 Sep 24;14(9):r105. doi: 10.1186/gb-2013-14-9-r105.

102.

Hospital contact for mental disorders in survivors of childhood cancer and their siblings in Denmark: a population-based cohort study.

Lund LW, Winther JF, Dalton SO, Cederkvist L, Jeppesen P, Deltour I, Hargreave M, Kjær SK, Jensen A, Rechnitzer C, Andersen KK, Schmiegelow K, Johansen C.

Lancet Oncol. 2013 Sep;14(10):971-80. doi: 10.1016/S1470-2045(13)70351-6. Epub 2013 Aug 14.

PMID:
23954078
103.

A 10-year follow up of reproductive function in women treated for childhood cancer.

Nielsen SN, Andersen AN, Schmidt KT, Rechnitzer C, Schmiegelow K, Bentzen JG, Larsen EC.

Reprod Biomed Online. 2013 Aug;27(2):192-200. doi: 10.1016/j.rbmo.2013.04.003. Epub 2013 Apr 18.

PMID:
23768622
104.

Second malignant neoplasms after treatment of childhood acute lymphoblastic leukemia.

Schmiegelow K, Levinsen MF, Attarbaschi A, Baruchel A, Devidas M, Escherich G, Gibson B, Heydrich C, Horibe K, Ishida Y, Liang DC, Locatelli F, Michel G, Pieters R, Piette C, Pui CH, Raimondi S, Silverman L, Stanulla M, Stark B, Winick N, Valsecchi MG.

J Clin Oncol. 2013 Jul 1;31(19):2469-76. doi: 10.1200/JCO.2012.47.0500. Epub 2013 May 20.

105.

Early morbidity and mortality in childhood acute lymphoblastic leukemia with very high white blood cell count.

Vaitkeviciene G, Heyman M, Jonsson OG, Lausen B, Harila-Saari A, Stenmarker M, Taskinen M, Zvirblis T, Åsberg A, Groth-Pedersen L, Rageliene L, Schmiegelow K.

Leukemia. 2013 Nov;27(11):2259-62. doi: 10.1038/leu.2013.137. Epub 2013 May 2. No abstract available.

PMID:
23689480
106.

Can SLC19A1 80G>A polymorphisms predict risk of extremely delayed MTX excretion after high dose of methotrexate?

Rasmussen MM, Christensen RH, Gregers J, Heldrup J, Nersting J, Schmiegelow K.

J Pediatr Hematol Oncol. 2013 Jul;35(5):417-8. doi: 10.1097/MPH.0b013e318290c11c. No abstract available.

PMID:
23669721
107.

Patterns of exposure to infectious diseases and social contacts in early life and risk of brain tumours in children and adolescents: an International Case-Control Study (CEFALO).

Andersen TV, Schmidt LS, Poulsen AH, Feychting M, Röösli M, Tynes T, Aydin D, Prochazka M, Lannering B, Klæboe L, Eggen T, Kuehni CE, Schmiegelow K, Schüz J.

Br J Cancer. 2013 Jun 11;108(11):2346-53. doi: 10.1038/bjc.2013.201. Epub 2013 May 7.

108.

Incorporation of 6-thioguanine nucleotides into DNA during maintenance therapy of childhood acute lymphoblastic leukemia-the influence of thiopurine methyltransferase genotypes.

Ebbesen MS, Nersting J, Jacobsen JH, Frandsen TL, Vettenranta K, Abramsson J, Wesenberg F, Schmiegelow K.

J Clin Pharmacol. 2013 Jun;53(6):670-4. doi: 10.1002/jcph.81. Epub 2013 Apr 15. No abstract available.

PMID:
23585236
109.

Use of azathioprine and the risk of cancer in inflammatory bowel disease.

Pasternak B, Svanström H, Schmiegelow K, Jess T, Hviid A.

Am J Epidemiol. 2013 Jun 1;177(11):1296-305. doi: 10.1093/aje/kws375. Epub 2013 Mar 20.

PMID:
23514635
110.

Treatment of children and adolescents with Hodgkin lymphoma without radiotherapy for patients in complete remission after chemotherapy: final results of the multinational trial GPOH-HD95.

Dörffel W, Rühl U, Lüders H, Claviez A, Albrecht M, Bökkerink J, Holte H, Karlen J, Mann G, Marciniak H, Niggli F, Schmiegelow K, Schwarze EW, Pötter R, Wickmann L, Schellong G.

J Clin Oncol. 2013 Apr 20;31(12):1562-8. doi: 10.1200/JCO.2012.45.3266. Epub 2013 Mar 18.

PMID:
23509321
111.

Fronto-cerebellar fiber tractography in pediatric patients following posterior fossa tumor surgery.

Gudrunardottir T, Sehested A, Juhler M, Schmiegelow K.

Childs Nerv Syst. 2013 May;29(5):715-6. doi: 10.1007/s00381-013-2070-3. Epub 2013 Mar 19. No abstract available.

PMID:
23508349
112.

Risk group assignment differs for children and adults 1-45 yr with acute lymphoblastic leukemia treated by the NOPHO ALL-2008 protocol.

Toft N, Birgens H, Abrahamsson J, Bernell P, Griškevičius L, Hallböök H, Heyman M, Holm MS, Hulegårdh E, Klausen TW, Marquart HV, Jónsson OG, Nielsen OJ, Quist-Paulsen P, Taskinen M, Vaitkeviciene G, Vettenranta K, Åsberg A, Schmiegelow K.

Eur J Haematol. 2013 May;90(5):404-12. doi: 10.1111/ejh.12097. Epub 2013 Apr 2.

PMID:
23461707
113.

Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update.

Relling MV, Gardner EE, Sandborn WJ, Schmiegelow K, Pui CH, Yee SW, Stein CM, Carrillo M, Evans WE, Hicks JK, Schwab M, Klein TE; Clinical Pharmacogenetics Implementation Consortium.

Clin Pharmacol Ther. 2013 Apr;93(4):324-5. doi: 10.1038/clpt.2013.4. Epub 2013 Jan 17. No abstract available.

114.

Hospital-based home care for children with cancer: feasibility and psychosocial impact on children and their families.

Hansson H, Kjaergaard H, Johansen C, Hallström I, Christensen J, Madsen M, Schmiegelow K.

Pediatr Blood Cancer. 2013 May;60(5):865-72. doi: 10.1002/pbc.24474. Epub 2013 Jan 17.

PMID:
23335455
115.

Birth weight in offspring and leukaemia risk in parents--a nation-wide register-based cohort study from Denmark.

Marklund M, Rostgaard K, Hjalgrim L, Schmiegelow K, Hjalgrim H.

Leuk Res. 2013 Feb;37(2):129-33. doi: 10.1016/j.leukres.2012.10.006. Epub 2012 Nov 24.

PMID:
23182976
116.

Physicians compliance during maintenance therapy in children with Down syndrome and acute lymphoblastic leukemia.

Bohnstedt C, Levinsen M, Rosthøj S, Zeller B, Taskinen M, Hafsteinsdottir S, Björgvinsdóttir H, Heyman M, Schmiegelow K; Nordic Society of Pediatric Hematology and Oncology (NOPHO).

Leukemia. 2013 Apr;27(4):866-70. doi: 10.1038/leu.2012.325. Epub 2012 Nov 9.

PMID:
23138181
117.

The thirteenth international childhood acute lymphoblastic leukemia workshop report: La Jolla, CA, USA, December 7-9, 2011.

Hunger SP, Baruchel A, Biondi A, Evans WE, Jeha S, Loh M, Moericke A, Pieters R, Relling MV, Schmiegelow K, Schrappe M, Silverman LB, Stanulla M, Valsecchi MG, Vora A, Pui CH.

Pediatr Blood Cancer. 2013 Feb;60(2):344-8. doi: 10.1002/pbc.24354. Epub 2012 Sep 28. No abstract available.

PMID:
23024117
118.

Hospitalisation for infection prior to diagnosis of acute lymphoblastic leukaemia in children.

Vestergaard TR, Rostgaard K, Grau K, Schmiegelow K, Hjalgrim H.

Pediatr Blood Cancer. 2013 Mar;60(3):428-32. doi: 10.1002/pbc.24286. Epub 2012 Aug 22.

PMID:
22915267
119.

Asparaginase-associated pancreatitis in children.

Raja RA, Schmiegelow K, Frandsen TL.

Br J Haematol. 2012 Oct;159(1):18-27. doi: 10.1111/bjh.12016. Epub 2012 Aug 22. Review.

PMID:
22909259
120.

Topical morphine for oral mucositis in children: dose finding and absorption.

Nielsen BN, Aagaard G, Henneberg SW, Schmiegelow K, Hansen SH, Rømsing J.

J Pain Symptom Manage. 2012 Jul;44(1):117-23. doi: 10.1016/j.jpainsymman.2011.06.029. Epub 2012 Jun 1.

PMID:
22658469
121.

Plasma cytokine profiles at diagnosis in pediatric patients with non-hodgkin lymphoma.

Mellgren K, Hedegaard CJ, Schmiegelow K, Müller K.

J Pediatr Hematol Oncol. 2012 May;34(4):271-5. doi: 10.1097/MPH.0b013e3182431e02.

PMID:
22430582
122.

Genome-wide analysis of cytogenetic aberrations in ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia.

Borst L, Wesolowska A, Joshi T, Borup R, Nielsen FC, Andersen MK, Jonsson OG, Wehner PS, Wesenberg F, Frost BM, Gupta R, Schmiegelow K.

Br J Haematol. 2012 May;157(4):476-82. doi: 10.1111/j.1365-2141.2012.09083.x. Epub 2012 Mar 7.

PMID:
22404039
123.

Clinical impact of leukemic blast heterogeneity at diagnosis in cytogenetic intermediate-risk acute myeloid leukemia.

Hoffmann MH, Klausen TW, Boegsted M, Larsen SF, Schmitz A, Leinoe EB, Schmiegelow K, Hasle H, Bergmann OJ, Sorensen S, Nyegaard M, Dybkaer K, Johnsen HE.

Cytometry B Clin Cytom. 2012 May;82(3):123-31. doi: 10.1002/cyto.b.20633. Epub 2012 Feb 10.

124.

Adult acute lymphoblastic leukaemia in Denmark. A national population-based retrospective study on acute lymphoblastic leukaemia in Denmark 1998-2008.

Toft N, Schmiegelow K, Klausen TW, Birgens H.

Br J Haematol. 2012 Apr;157(1):97-104. doi: 10.1111/j.1365-2141.2011.09020.x. Epub 2012 Jan 11.

PMID:
22233128
125.

RT-PCR screening for ETV6-RUNX1-positive clones in cord blood from newborns in the Danish National Birth Cohort.

Olsen M, Hjalgrim H, Melbye M, Madsen HO, Schmiegelow K.

J Pediatr Hematol Oncol. 2012 May;34(4):301-3. doi: 10.1097/MPH.0b013e3182332268.

PMID:
22217495
126.

Gene dose effects of GSTM1, GSTT1 and GSTP1 polymorphisms on outcome in childhood acute lymphoblastic leukemia.

Borst L, Buchard A, Rosthøj S, Wesolowska A, Wehner PS, Wesenberg F, Dalhoff K, Schmiegelow K.

J Pediatr Hematol Oncol. 2012 Jan;34(1):38-42. doi: 10.1097/MPH.0b013e3182346cdd.

PMID:
22215096
127.

Liquid chromatography-tandem mass spectrometry quantification of 6-thioguanine in DNA using endogenous guanine as internal standard.

Jacobsen JH, Schmiegelow K, Nersting J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jan 15;881-882:115-8. doi: 10.1016/j.jchromb.2011.11.032. Epub 2011 Nov 28.

PMID:
22178190
128.

Hepatoblastoma in the Nordic countries.

de Fine Licht S, Schmidt LS, Rod NH, Schmiegelow K, Lähteenmäki PM, Kogner P, Träger C, Stokland T, Schüz J.

Int J Cancer. 2012 Aug 15;131(4):E555-61. doi: 10.1002/ijc.27351. Epub 2012 Jan 3.

129.

Estimation of dynamic treatment strategies for maintenance therapy of children with acute lymphoblastic leukaemia: an application of history-adjusted marginal structural models.

Rosthøj S, Keiding N, Schmiegelow K.

Stat Med. 2012 Feb 28;31(5):470-88. doi: 10.1002/sim.4393. Epub 2011 Nov 15.

PMID:
22086750
130.

High concordance of subtypes of childhood acute lymphoblastic leukemia within families: lessons from sibships with multiple cases of leukemia.

Schmiegelow K, Lausten Thomsen U, Baruchel A, Pacheco CE, Pieters R, Pombo-de-Oliveira MS, Andersen EW, Rostgaard K, Hjalgrim H, Pui CH.

Leukemia. 2012 Apr;26(4):675-81. doi: 10.1038/leu.2011.274. Epub 2011 Oct 18.

PMID:
22005784
131.

Marriage and divorce among childhood cancer survivors.

Koch SV, Kejs AM, Engholm G, Møller H, Johansen C, Schmiegelow K.

J Pediatr Hematol Oncol. 2011 Oct;33(7):500-5. doi: 10.1097/MPH.0b013e31822820a1.

PMID:
21941142
132.

Identification of residual leukemic cells by flow cytometry in childhood B-cell precursor acute lymphoblastic leukemia: verification of leukemic state by flow-sorting and molecular/cytogenetic methods.

Øbro NF, Ryder LP, Madsen HO, Andersen MK, Lausen B, Hasle H, Schmiegelow K, Marquart HV.

Haematologica. 2012 Jan;97(1):137-41. doi: 10.3324/haematol.2011.051383. Epub 2011 Sep 20.

133.

Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia.

Nersting J, Borst L, Schmiegelow K.

Clin Proteomics. 2011 Jun 3;8(1):8. doi: 10.1186/1559-0275-8-8.

134.

Pneumocystis jiroveci pneumonia prophylaxis during maintenance therapy influences methotrexate/6-mercaptopurine dosing but not event-free survival for childhood acute lymphoblastic leukemia.

Levinsen M, Shabaneh D, Bohnstedt C, Harila-Saari A, Jonsson OG, Kanerva J, Lindblom A, Lund B, Andersen EW, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

Eur J Haematol. 2012 Jan;88(1):78-86. doi: 10.1111/j.1600-0609.2011.01695.x. Epub 2011 Oct 2.

PMID:
21854453
135.

Hospital-based home care for children with cancer: a qualitative exploration of family members' experiences in Denmark.

Hansson H, Kjaergaard H, Schmiegelow K, Hallström I.

Eur J Cancer Care (Engl). 2012 Jan;21(1):59-66. doi: 10.1111/j.1365-2354.2011.01280.x. Epub 2011 Aug 18.

PMID:
21848580
136.

Individualized toxicity-titrated 6-mercaptopurine increments during high-dose methotrexate consolidation treatment of lower risk childhood acute lymphoblastic leukaemia. A Nordic Society of Paediatric Haematology and Oncology (NOPHO) pilot study.

Frandsen TL, Abrahamsson J, Lausen B, Vettenranta K, Heyman M, Behrentz M, Castor A, Wehner PS, Frost BM, Andersen EW, Schmiegelow K.

Br J Haematol. 2011 Oct;155(2):244-7. doi: 10.1111/j.1365-2141.2011.08835.x. Epub 2011 Aug 18.

PMID:
21848519
137.

Duration of adrenal insufficiency during treatment for childhood acute lymphoblastic leukemia.

Vestergaard TR, Juul A, Lausten-Thomsen U, Lausen B, Hjalgrim H, Kvist TK, Andersen EW, Schmiegelow K.

J Pediatr Hematol Oncol. 2011 Aug;33(6):442-9. doi: 10.1097/MPH.0b013e3182260cbe.

PMID:
21792040
138.

Cerebellar mutism: definitions, classification and grading of symptoms.

Gudrunardottir T, Sehested A, Juhler M, Grill J, Schmiegelow K.

Childs Nerv Syst. 2011 Sep;27(9):1361-3. doi: 10.1007/s00381-011-1509-7. Epub 2011 Jul 6. No abstract available.

PMID:
21732118
139.

Epidemiology of therapy-related myeloid neoplasms after treatment for pediatric acute lymphoblastic leukemia in the nordic countries.

Schmiegelow K.

Mediterr J Hematol Infect Dis. 2011;3(1):e2011020. doi: 10.4084/MJHID.2011.020. Epub 2011 May 16.

140.

Immunophenotype-defined sub-populations are common at diagnosis in childhood B-cell precursor acute lymphoblastic leukemia.

Øbro NF, Marquart HV, Madsen HO, Ryder LP, Andersen MK, Lausen B, Albertsen BK, Wehner PS, Helgestad J, Schmiegelow K.

Leukemia. 2011 Oct;25(10):1652-7. doi: 10.1038/leu.2011.136. Epub 2011 Jun 17. No abstract available.

PMID:
21681192
141.

Hospital-based home care for children with cancer.

Hansson H, Hallström I, Kjaergaard H, Johansen C, Schmiegelow K.

Pediatr Blood Cancer. 2011 Sep;57(3):369-77. doi: 10.1002/pbc.23047. Epub 2011 May 18. Review.

PMID:
21594980
142.

Approaches for cytogenetic and molecular analyses of small flow-sorted cell populations from childhood leukemia bone marrow samples.

Obro NF, Madsen HO, Ryder LP, Andersen MK, Schmiegelow K, Marquart HV.

J Immunol Methods. 2011 Jun 30;369(1-2):69-73. doi: 10.1016/j.jim.2011.04.007. Epub 2011 May 6.

PMID:
21570982
143.

The impact of CYP3A5*3 on risk and prognosis in childhood acute lymphoblastic leukemia.

Borst L, Wallerek S, Dalhoff K, Rasmussen KK, Wesenberg F, Wehner PS, Schmiegelow K.

Eur J Haematol. 2011 Jun;86(6):477-83. doi: 10.1111/j.1600-0609.2011.01608.x.

PMID:
21418106
144.

Cost-effective multiplexing before capture allows screening of 25 000 clinically relevant SNPs in childhood acute lymphoblastic leukemia.

Wesolowska A, Dalgaard MD, Borst L, Gautier L, Bak M, Weinhold N, Nielsen BF, Helt LR, Audouze K, Nersting J, Tommerup N, Brunak S, Sicheritz-Ponten T, Leffers H, Schmiegelow K, Gupta R.

Leukemia. 2011 Jun;25(6):1001-6. doi: 10.1038/leu.2011.32. Epub 2011 Mar 18.

PMID:
21415851
145.

Cerebellar mutism: incidence, risk factors and prognosis.

Gudrunardottir T, Sehested A, Juhler M, Schmiegelow K.

Childs Nerv Syst. 2011 Apr;27(4):513-4; author reply 515. doi: 10.1007/s00381-010-1383-8. Epub 2011 Feb 12. No abstract available.

PMID:
21318616
146.

Risk factors for treatment related mortality in childhood acute lymphoblastic leukaemia.

Lund B, Åsberg A, Heyman M, Kanerva J, Harila-Saari A, Hasle H, Söderhäll S, Jónsson ÓG, Lydersen S, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology.

Pediatr Blood Cancer. 2011 Apr;56(4):551-9. doi: 10.1002/pbc.22719. Epub 2010 Dec 8.

PMID:
21298739
147.

A systematic review of studies on psychosocial late effects of childhood cancer: structures of society and methodological pitfalls may challenge the conclusions.

Lund LW, Schmiegelow K, Rechnitzer C, Johansen C.

Pediatr Blood Cancer. 2011 Apr;56(4):532-43. doi: 10.1002/pbc.22883. Epub 2010 Dec 7.

PMID:
21298737
148.

Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.

Relling MV, Gardner EE, Sandborn WJ, Schmiegelow K, Pui CH, Yee SW, Stein CM, Carrillo M, Evans WE, Klein TE; Clinical Pharmacogenetics Implementation Consortium.

Clin Pharmacol Ther. 2011 Mar;89(3):387-91. doi: 10.1038/clpt.2010.320. Epub 2011 Jan 26. Erratum in: Clin Pharmacol Ther. 2011 Dec;90(6):894.

149.

Treatment-related deaths in second complete remission in childhood acute myeloid leukaemia.

Molgaard-Hansen L, Möttönen M, Glosli H, Jónmundsson GK, Abrahamsson J, Hasle H; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

Br J Haematol. 2011 Mar;152(5):623-30. doi: 10.1111/j.1365-2141.2010.08554.x. Epub 2011 Jan 17.

PMID:
21241281
150.

Febrile infections in young children do not frequently induce translocation ETV6-RUNX1.

Olsen M, Nielsen NK, Birkballe S, Hjalgrim H, Madsen HO, Schmiegelow K.

Blood Cells Mol Dis. 2011 Feb 15;46(2):175-6. doi: 10.1016/j.bcmd.2010.11.003. Epub 2010 Dec 8. No abstract available.

PMID:
21145270
151.

Incidence of childhood central nervous system tumors in the Nordic countries.

Schmidt LS, Schmiegelow K, Lahteenmaki P, Träger C, Stokland T, Grell K, Gustafson G, Sehested A, Raashou-Nielsen O, Johansen C, Schüz J.

Pediatr Blood Cancer. 2011 Jan;56(1):65-9. doi: 10.1002/pbc.22585.

PMID:
21108441
152.

High white blood cell count at diagnosis of childhood acute lymphoblastic leukaemia: biological background and prognostic impact. Results from the NOPHO ALL-92 and ALL-2000 studies.

Vaitkevičienė G, Forestier E, Hellebostad M, Heyman M, Jonsson OG, Lähteenmäki PM, Rosthoej S, Söderhäll S, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

Eur J Haematol. 2011 Jan;86(1):38-46. doi: 10.1111/j.1600-0609.2010.01522.x. Epub 2010 Nov 15.

PMID:
21077959
153.

Cerebellar mutism: review of the literature.

Gudrunardottir T, Sehested A, Juhler M, Schmiegelow K.

Childs Nerv Syst. 2011 Mar;27(3):355-63. doi: 10.1007/s00381-010-1328-2. Review.

PMID:
21061011
154.

In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia.

Lönnerholm G, Thörn I, Sundström C, Frost BM, Flaegstad T, Heyman M, Jonsson OG, Harila-Saari A, Madsen HO, Porwit A, Schmiegelow K, Söderhäll S, Wesenberg F, Vettenranta K, Larsson R, Forestier E.

Leuk Res. 2011 Apr;35(4):472-8. doi: 10.1016/j.leukres.2010.09.001. Epub 2010 Oct 18.

PMID:
20961616
155.

The controversy of varicella vaccination in children with acute lymphoblastic leukemia.

Caniza MA, Hunger SP, Schrauder A, Valsecchi MG, Pui CH, Masera G; Members of International Study Group of Childhood ALL ( “Ponte di Legno Working Group”).

Pediatr Blood Cancer. 2012 Jan;58(1):12-6. doi: 10.1002/pbc.22759. Epub 2010 Sep 16.

156.

Prevalence of t(12;21)[ETV6-RUNX1]-positive cells in healthy neonates.

Lausten-Thomsen U, Madsen HO, Vestergaard TR, Hjalgrim H, Nersting J, Schmiegelow K.

Blood. 2011 Jan 6;117(1):186-9. doi: 10.1182/blood-2010-05-282764. Epub 2010 Aug 16.

157.

Birth characteristics and Wilms tumors in children in the Nordic countries: a register-based case-control study.

Schüz J, Schmidt LS, Kogner P, Lähteenmäki PM, Pal N, Stokland T, Schmiegelow K.

Int J Cancer. 2011 May 1;128(9):2166-73. doi: 10.1002/ijc.25541.

158.

Clinical and biochemical correlates of successful semen collection for cryopreservation from 12-18-year-old patients: a single-center study of 86 adolescents.

Hagenäs I, Jørgensen N, Rechnitzer C, Sommer P, Holm M, Schmiegelow K, Daugaard G, Jacobsen N, Juul A.

Hum Reprod. 2010 Aug;25(8):2031-8. doi: 10.1093/humrep/deq147. Epub 2010 Jun 22.

PMID:
20570975
159.

Infectious exposure in the first years of life and risk of central nervous system tumours in children: analysis of birth order, childcare attendance and seasonality of birth.

Schmidt LS, Kamper-Jørgensen M, Schmiegelow K, Johansen C, Lähteenmäki P, Träger C, Stokland T, Grell K, Gustafson G, Kogner P, Sehested A, Schüz J.

Br J Cancer. 2010 May 25;102(11):1670-5. doi: 10.1038/sj.bjc.6605679. Epub 2010 May 11.

160.

The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number.

Gregers J, Christensen IJ, Dalhoff K, Lausen B, Schroeder H, Rosthoej S, Carlsen N, Schmiegelow K, Peterson C.

Blood. 2010 Jun 10;115(23):4671-7. doi: 10.1182/blood-2010-01-256958. Epub 2010 Mar 24.

161.

Fetal growth, preterm birth, neonatal stress and risk for CNS tumors in children: a Nordic population- and register-based case-control study.

Schmidt LS, Schüz J, Lähteenmäki P, Träger C, Stokland T, Gustafson G, Hjalgrim L, Sehested A, Johansen C, Schmiegelow K.

Cancer Epidemiol Biomarkers Prev. 2010 Apr;19(4):1042-52. doi: 10.1158/1055-9965.EPI-09-1273. Epub 2010 Mar 23.

162.

'Educational symposium on long-term results of large prospective clinical trials for childhood acute lymphoblastic leukemia (1985-2000)'.

Schrappe M, Nachman J, Hunger S, Schmiegelow K, Conter V, Masera G, Pieters R, Pui CH.

Leukemia. 2010 Feb;24(2):253-4. doi: 10.1038/leu.2009.276. No abstract available.

PMID:
20145664
163.

The degree of myelosuppression during maintenance therapy of adolescents with B-lineage intermediate risk acute lymphoblastic leukemia predicts risk of relapse.

Schmiegelow K, Heyman M, Gustafsson G, Lausen B, Wesenberg F, Kristinsson J, Vettenranta K, Schroeder H, Forestier E, Rosthoej S; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

Leukemia. 2010 Apr;24(4):715-20. doi: 10.1038/leu.2009.303. Epub 2010 Feb 4.

PMID:
20130603
164.

Increased risk of ALL among premature infants is not explained by increased prevalence of pre-leukemic cell clones.

Lausten-Thomsen U, Madsen HO, Vestergaard TR, Hjalgrim H, Lando A, Schmiegelow K.

Blood Cells Mol Dis. 2010 Mar 15;44(3):188-90. doi: 10.1016/j.bcmd.2009.12.007. Epub 2010 Jan 15.

PMID:
20079669
165.

Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008.

Brüggemann M, Schrauder A, Raff T, Pfeifer H, Dworzak M, Ottmann OG, Asnafi V, Baruchel A, Bassan R, Benoit Y, Biondi A, Cavé H, Dombret H, Fielding AK, Foà R, Gökbuget N, Goldstone AH, Goulden N, Henze G, Hoelzer D, Janka-Schaub GE, Macintyre EA, Pieters R, Rambaldi A, Ribera JM, Schmiegelow K, Spinelli O, Stary J, von Stackelberg A, Kneba M, Schrappe M, van Dongen JJ; European Working Group for Adult Acute Lymphoblastic Leukemia (EWALL); International Berlin-Frankfurt-Münster Study Group (I-BFM-SG).

Leukemia. 2010 Mar;24(3):521-35. doi: 10.1038/leu.2009.268. Epub 2009 Dec 24. Review.

PMID:
20033054
166.

Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia.

Schmiegelow K, Forestier E, Hellebostad M, Heyman M, Kristinsson J, Söderhäll S, Taskinen M; Nordic Society of Paediatric Haematology and Oncology.

Leukemia. 2010 Feb;24(2):345-54. doi: 10.1038/leu.2009.251. Epub 2009 Dec 10. Erratum in: Leukemia. 2010 Mar;24(3):670.

PMID:
20010622
167.

DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia.

Milani L, Lundmark A, Kiialainen A, Nordlund J, Flaegstad T, Forestier E, Heyman M, Jonmundsson G, Kanerva J, Schmiegelow K, Söderhäll S, Gustafsson MG, Lönnerholm G, Syvänen AC.

Blood. 2010 Feb 11;115(6):1214-25. doi: 10.1182/blood-2009-04-214668. Epub 2009 Nov 25.

168.

Pharmacogenomics of methotrexate: moving towards individualized therapy.

Nersting J, Schmiegelow K.

Pharmacogenomics. 2009 Dec;10(12):1887-9. doi: 10.2217/pgs.09.148. No abstract available.

169.

DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma.

Hedeland RL, Hvidt K, Nersting J, Rosthøj S, Dalhoff K, Lausen B, Schmiegelow K.

Cancer Chemother Pharmacol. 2010 Aug;66(3):485-91. doi: 10.1007/s00280-009-1184-5. Epub 2009 Dec 3.

PMID:
19956952
170.

The Eleventh International Childhood Acute Lymphoblastic Leukemia Workshop Report: Ponte di Legno, Italy, 6-7 May 2009.

Biondi A, Baruchel A, Hunger S, Masera G, Schmiegelow K, Schrappe M, Pui CH.

Leukemia. 2009 Dec;23(12):2318-24. doi: 10.1038/leu.2009.211. Epub 2009 Nov 5.

171.

[Evaluation of trainee doctors' skills].

Nygaard U, Nielsen HS, Schmidt IM, Nysom K, Schmiegelow K, Sørensen JL.

Ugeskr Laeger. 2009 Sep 14;171(38):2742-5. Danish.

PMID:
19758498
172.

Characterizing chromosomal break points of t(12;21)[ETV6-RUNX1]-positive leukaemia using multiple tiling PCR on whole-genome-amplified DNA.

Lausten-Thomsen U, Madsen HO, Schmiegelow K.

Leukemia. 2010 Jan;24(1):203-5. doi: 10.1038/leu.2009.170. Epub 2009 Aug 27. No abstract available.

PMID:
19710699
173.

Allergy and the risk of childhood leukemia: a meta-analysis.

Dahl S, Schmidt LS, Vestergaard T, Schüz J, Schmiegelow K.

Leukemia. 2009 Dec;23(12):2300-4. doi: 10.1038/leu.2009.162. Epub 2009 Aug 6. No abstract available.

PMID:
19657364
174.

Oral methotrexate/6-mercaptopurine may be superior to a multidrug LSA2L2 Maintenance therapy for higher risk childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

Schmiegelow K, Heyman M, Kristinsson J, Mogensen UB, Rosthøj S, Vettenranta K, Wesenberg F, Saarinen-Pihkala U; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

J Pediatr Hematol Oncol. 2009 Jun;31(6):385-92. doi: 10.1097/MPH.0b013e3181a6e171.

PMID:
19648786
175.

Advances in individual prediction of methotrexate toxicity: a review.

Schmiegelow K.

Br J Haematol. 2009 Sep;146(5):489-503. doi: 10.1111/j.1365-2141.2009.07765.x. Epub 2009 Jun 15. Review.

PMID:
19538530
176.

Health-related quality of life in long-term survivors of childhood brain tumors.

Reimers TS, Mortensen EL, Nysom K, Schmiegelow K.

Pediatr Blood Cancer. 2009 Dec;53(6):1086-91. doi: 10.1002/pbc.22122.

PMID:
19499581
177.

Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia.

Palle J, Frost BM, Petersson C, Hasle H, Hellebostad M, Kanerva J, Schmiegelow K, Lönnerholm G; Nordic Society for Paediatric Haematology and Oncology.

Anticancer Drugs. 2009 Jan;20(1):7-14. doi: 10.1097/CAD.0b013e32831bc086. Erratum in: Anticancer Drugs. 2010 Jan;21(1):130. Josefine, Palle [corrected to Palle, Josefine]; Britt-Marie, Frost [corrected to Frost, Britt-Marie]; Curt, Petersson [corrected to Petersson, Curt]; Henrik, Hasle [corrected to Hasle, Henrik]; Marit, Hellebostad [corrected to Hellebostad, Marit]; Jukka, K.

PMID:
19342996
178.

Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

Schmiegelow K, Al-Modhwahi I, Andersen MK, Behrendtz M, Forestier E, Hasle H, Heyman M, Kristinsson J, Nersting J, Nygaard R, Svendsen AL, Vettenranta K, Weinshilboum R; Nordic Society for Paediatric Haematology and Oncology.

Blood. 2009 Jun 11;113(24):6077-84. doi: 10.1182/blood-2008-11-187880. Epub 2009 Feb 17.

179.

Poor treatment compliance in children with down syndrome and acute lymphoblastic leukemia.

Bohnstedt C, Taskinen M, Zeller B, Björgvinsdóttir H, Hafsteinsdottir S, Schmiegelow K.

J Pediatr Hematol Oncol. 2009 Jan;31(1):79-80. doi: 10.1097/MPH.0b013e31818b37a9. No abstract available.

PMID:
19125098
180.

Seasonality of birth in children with central nervous system tumours in Denmark, 1970-2003.

Schmidt LS, Grell K, Frederiksen K, Johansen C, Schmiegelow K, Schüz J.

Br J Cancer. 2009 Jan 13;100(1):185-7. doi: 10.1038/sj.bjc.6604813. Epub 2008 Dec 9.

181.

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation.

Milani L, Lundmark A, Nordlund J, Kiialainen A, Flaegstad T, Jonmundsson G, Kanerva J, Schmiegelow K, Gunderson KL, Lönnerholm G, Syvänen AC.

Genome Res. 2009 Jan;19(1):1-11. doi: 10.1101/gr.083931.108. Epub 2008 Nov 7.

182.

Pharmacogenetics influence treatment efficacy in childhood acute lymphoblastic leukemia.

Davidsen ML, Dalhoff K, Schmiegelow K.

J Pediatr Hematol Oncol. 2008 Nov;30(11):831-49. doi: 10.1097/MPH.0b013e3181868570. Review.

PMID:
18989161
183.

Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

Schmiegelow K, Forestier E, Kristinsson J, Söderhäll S, Vettenranta K, Weinshilboum R, Wesenberg F; Nordic Society of Paediatric Haematology and Oncology.

Leukemia. 2009 Mar;23(3):557-64. doi: 10.1038/leu.2008.316. Epub 2008 Nov 6.

184.

Azathioprine treatment during lactation.

Christensen LA, Dahlerup JF, Nielsen MJ, Fallingborg JF, Schmiegelow K.

Aliment Pharmacol Ther. 2008 Nov 15;28(10):1209-13. doi: 10.1111/j.1365-2036.2008.03843.x. Epub 2008 Aug 30.

185.

Etiology of common childhood acute lymphoblastic leukemia: the adrenal hypothesis.

Schmiegelow K, Vestergaard T, Nielsen SM, Hjalgrim H.

Leukemia. 2008 Dec;22(12):2137-41. doi: 10.1038/leu.2008.212. Epub 2008 Aug 21. Review.

PMID:
18719616
186.

Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate.

van Kooten Niekerk PB, Schmiegelow K, Schroeder H.

Eur J Haematol. 2008 Nov;81(5):391-8. doi: 10.1111/j.1600-0609.2008.01128.x. Epub 2008 Aug 6.

PMID:
18691257
187.

Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids.

Lönnerholm G, Nordgren A, Frost BM, Jonsson OG, Kanerva J, Nygaard R, Schmiegelow K, Larsson R, Forestier E.

Leukemia. 2009 Jan;23(1):209-12. doi: 10.1038/leu.2008.179. Epub 2008 Jul 10. No abstract available.

PMID:
18615108
188.

ETV6-RUNX1 transcript is not frequent in early human haematopoiesis.

Lausten-Thomsen U, Hjalgrim H, Marquart H, Lutterodt M, Petersen BL, Schmiegelow K.

Eur J Haematol. 2008 Aug;81(2):161-2. doi: 10.1111/j.1600-0609.2008.01091.x. Epub 2008 May 6. No abstract available.

PMID:
18462252
189.

T-cell receptor Vbeta CDR3 oligoclonality frequently occurs in childhood refractory cytopenia (MDS-RC) and severe aplastic anemia.

de Vries AC, Langerak AW, Verhaaf B, Niemeyer CM, Stary J, Schmiegelow K, van Wering ER, Zwaan CM, Beishuizen A, Pieters R, van den Heuvel-Eibrink MM.

Leukemia. 2008 Jun;22(6):1170-4. doi: 10.1038/leu.2008.23. Epub 2008 Mar 6.

PMID:
18323803
190.

Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection.

Olesen KM, Hansen SH, Sidenius U, Schmiegelow K.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Mar 15;864(1-2):149-55. doi: 10.1016/j.jchromb.2008.02.007. Epub 2008 Feb 20.

PMID:
18313997
191.

High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphoblastic leukemia.

von Stackelberg A, Hartmann R, Bührer C, Fengler R, Janka-Schaub G, Reiter A, Mann G, Schmiegelow K, Ratei R, Klingebiel T, Ritter J, Henze G; ALL-REZ BFM Study Group.

Blood. 2008 Mar 1;111(5):2573-80. Epub 2007 Dec 18.

192.
193.

Childcare in the first 2 years of life reduces the risk of childhood acute lymphoblastic leukemia.

Kamper-Jørgensen M, Woodward A, Wohlfahrt J, Benn CS, Simonsen J, Hjalgrim H, Schmiegelow K.

Leukemia. 2008 Jan;22(1):189-93. Epub 2007 Aug 9. No abstract available.

PMID:
17690702
194.

[Procalcitonin for early diagnosis of bacteraemia in children with cancer].

Chawes BL, Rechnitzer C, Schmiegelow K, Tvede M.

Ugeskr Laeger. 2007 Jan 8;169(2):138-42. Danish.

PMID:
17227662
195.

Genetic analyses of thiopurine methyltransferase polymorphisms in Greenlandic and Danish populations.

Toft N, Nygaard U, Gregers J, Schmiegelow K.

Acta Paediatr. 2006 Dec;95(12):1665-7.

PMID:
17129980
196.

Preleukemic TEL-AML1-positive clones at cell level of 10(-3) to 10(-4) do not persist into adulthood.

Olsen M, Madsen HO, Hjalgrim H, Gregers J, Rostgaard K, Schmiegelow K.

J Pediatr Hematol Oncol. 2006 Nov;28(11):734-40.

PMID:
17114960
197.

Stability of cord blood RNA measured by house keeping transcripts: relevance for large-scale studies of childhood leukaemia.

Olsen M, Madsen HO, Hjalgrim H, Ford A, Schmiegelow K.

Leukemia. 2006 Dec;20(12):2214-7. Epub 2006 Oct 19. No abstract available.

PMID:
17051240
198.

Etoposide pharmacokinetics in children treated for acute myeloid leukemia.

Palle J, Frost BM, Gustafsson G, Hellebostad M, Kanerva J, Liliemark E, Schmiegelow K, Lönnerholm G; Nordic Society of Paediatric Haematology and Oncology.

Anticancer Drugs. 2006 Oct;17(9):1087-94. Erratum in: Anticancer Drugs. 2010 Jan;21(1):129. Britt-Marie, Frost [corrected to Frost, Britt-Marie]; Göran, Gustafsson [corrected to Gustafsson, Göran]; Marit, Hellebostad [corrected to Hellebostad, Marit]; Jukka, Kanerva [corrected to Kanerva, Jukka]; Eva, Liliemark [corrected to Liliemark, Eva]; Kj.

PMID:
17001183
199.

High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia.

Skärby TV, Anderson H, Heldrup J, Kanerva JA, Seidel H, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

Leukemia. 2006 Nov;20(11):1955-62. Epub 2006 Sep 21.

PMID:
16990760
200.

The incidence peaks of the childhood acute leukemias reflect specific cytogenetic aberrations.

Forestier E, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology NOPHO.

J Pediatr Hematol Oncol. 2006 Aug;28(8):486-95.

PMID:
16912588

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