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Items: 1 to 200 of 235

1.

Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma.

Dimopoulos K, Fibiger Munch-Petersen H, Winther Eskelund C, Dissing Sjö L, Ralfkiaer E, Gimsing P, Grønbaek K.

Leuk Lymphoma. 2018 May 2:1-9. doi: 10.1080/10428194.2018.1466290. [Epub ahead of print]

PMID:
29718735
2.

Heading for centennial anniversary and beyond.

Norrild B, Ralfkiaer E, Bjarnsholt T, Jensen PØ.

APMIS. 2017 Dec;125(12):1133. doi: 10.1111/apm.12797. No abstract available.

PMID:
29193348
3.

Clinicopathological Features of Ocular Adnexal Mantle-Cell Lymphoma in an International Multicenter Cohort.

Knudsen MKH, Rasmussen PK, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Khong JJ, McKelvie PA, Mulay K, Ralfkiaer E, Sjö LD, Vemuganti GK, Thuro BA, Curtin J, Heegaard S.

JAMA Ophthalmol. 2017 Dec 1;135(12):1367-1374. doi: 10.1001/jamaophthalmol.2017.4810.

PMID:
29121219
4.

Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma.

Wedge E, Hansen JW, Garde C, Asmar F, Tholstrup D, Kristensen SS, Munch-Petersen HD, Ralfkiaer E, Brown P, Grønbaek K, Kristensen LS.

Am J Hematol. 2017 Jul;92(7):689-694. doi: 10.1002/ajh.24751. Epub 2017 May 3.

5.

Lymphoma of the Eyelid - An International Multicenter Retrospective Study.

Svendsen FH, Rasmussen PK, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, Khong JJ, McKelvie PA, Mulay K, Ralfkiaer E, Sjö LD, Vemuganti GK, Thuro BA, Curtin J, Heegaard S.

Am J Ophthalmol. 2017 May;177:58-68. doi: 10.1016/j.ajo.2017.02.004. Epub 2017 Feb 14.

PMID:
28209503
6.
7.

Molecular Monitoring after Autologous Stem Cell Transplantation and Preemptive Rituximab Treatment of Molecular Relapse; Results from the Nordic Mantle Cell Lymphoma Studies (MCL2 and MCL3) with Median Follow-Up of 8.5 Years.

Kolstad A, Pedersen LB, Eskelund CW, Husby S, Grønbæk K, Jerkeman M, Laurell A, Räty R, Elonen E, Andersen NS, Brown PD, Kimby E, Bentzen H, Sundström C, Ehinger M, Karjalainen-Lindsberg ML, Delabie J, Ralfkiær E, Fagerli UM, Nilsson-Ehle H, Lauritzsen GF, Kuittinen O, Niemann C, Geisler CH; Nordic Lymphoma Group.

Biol Blood Marrow Transplant. 2017 Mar;23(3):428-435. doi: 10.1016/j.bbmt.2016.12.634. Epub 2016 Dec 27.

8.

TP53 Gene Status Affects Survival in Advanced Mycosis Fungoides.

Wooler G, Melchior L, Ralfkiaer E, Rahbek Gjerdrum LM, Gniadecki R.

Front Med (Lausanne). 2016 Nov 11;3:51. eCollection 2016.

9.

15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau.

Eskelund CW, Kolstad A, Jerkeman M, Räty R, Laurell A, Eloranta S, Smedby KE, Husby S, Pedersen LB, Andersen NS, Eriksson M, Kimby E, Bentzen H, Kuittinen O, Lauritzsen GF, Nilsson-Ehle H, Ralfkiaer E, Ehinger M, Sundström C, Delabie J, Karjalainen-Lindsberg ML, Workman CT, Garde C, Elonen E, Brown P, Grønbaek K, Geisler CH.

Br J Haematol. 2016 Nov;175(3):410-418. doi: 10.1111/bjh.14241. Epub 2016 Jul 5.

PMID:
27378674
10.

MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1-Infected Individuals and Are Associated With Markers of Systemic Inflammation.

Ballegaard V, Ralfkiaer U, Pedersen KK, Hove M, Koplev S, Brændstrup P, Ryder LP, Madsen HO, Gerstoft J, Grønbæk K, Nielsen SD.

J Acquir Immune Defic Syndr. 2017 Apr 1;74(4):e104-e113. doi: 10.1097/QAI.0000000000001191.

PMID:
27749601
11.

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.

Mansouri L, Noerenberg D, Young E, Mylonas E, Abdulla M, Frick M, Asmar F, Ljungström V, Schneider M, Yoshida K, Skaftason A, Pandzic T, Gonzalez B, Tasidou A, Waldhueter N, Rivas-Delgado A, Angelopoulou M, Ziepert M, Arends CM, Couronné L, Lenze D, Baldus CD, Bastard C, Okosun J, Fitzgibbon J, Dörken B, Drexler HG, Roos-Weil D, Schmitt CA, Munch-Petersen HD, Zenz T, Hansmann ML, Strefford JC, Enblad G, Bernard OA, Ralfkiaer E, Erlanson M, Korkolopoulou P, Hultdin M, Papadaki T, Grønbæk K, Lopez-Guillermo A, Ogawa S, Küppers R, Stamatopoulos K, Stavroyianni N, Kanellis G, Rosenwald A, Campo E, Amini RM, Ott G, Vassilakopoulos TP, Hummel M, Rosenquist R, Damm F.

Blood. 2016 Dec 8;128(23):2666-2670. Epub 2016 Sep 26.

12.

Lenalidomide-bendamustine-rituximab in patients older than 65 years with untreated mantle cell lymphoma.

Albertsson-Lindblad A, Kolstad A, Laurell A, Räty R, Grønbæk K, Sundberg J, Pedersen LB, Ralfkiær E, Karjalainen-Lindsberg ML, Sundström C, Ehinger M, Geisler C, Jerkeman M.

Blood. 2016 Oct 6;128(14):1814-1820. doi: 10.1182/blood-2016-03-704023. Epub 2016 Jun 27.

13.

STAT5 induces miR-21 expression in cutaneous T cell lymphoma.

Lindahl LM, Fredholm S, Joseph C, Nielsen BS, Jønson L, Willerslev-Olsen A, Gluud M, Blümel E, Petersen DL, Sibbesen N, Hu T, Nastasi C, Krejsgaard T, Jæhger D, Persson JL, Mongan N, Wasik MA, Litvinov IV, Sasseville D, Koralov SB, Bonefeld CM, Geisler C, Woetmann A, Ralfkiaer E, Iversen L, Odum N.

Oncotarget. 2016 Jul 19;7(29):45730-45744. doi: 10.18632/oncotarget.10160.

14.

TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy.

Munch-Petersen HD, Asmar F, Dimopoulos K, Areškevičiūtė A, Brown P, Girkov MS, Pedersen A, Sjö LD, Heegaard S, Broholm H, Kristensen LS, Ralfkiaer E, Grønbæk K.

Acta Neuropathol Commun. 2016 Apr 22;4:40. doi: 10.1186/s40478-016-0307-6.

15.

Conjunctival Lymphoma--An International Multicenter Retrospective Study.

Kirkegaard MM, Rasmussen PK, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, Khong JJ, McKelvie PA, Mulay K, Prause JU, Ralfkiaer E, Sjö LD, Toft PB, Vemuganti GK, Thuro BA, Curtin J, Heegaard S.

JAMA Ophthalmol. 2016 Apr;134(4):406-14. doi: 10.1001/jamaophthalmol.2015.6122.

PMID:
26891973
16.

WHO classification 2008 of myeloproliferative neoplasms: a workshop learning effect--the Danish experience.

Madelung AB, Bondo H, Stamp I, Løvgreen P, Nielsen SL, Falensteen A, Knudsen H, Svendsen KD, Lange T, Ralfkiaer E, Nielsen K, Hasselbalch H, Thiele J.

APMIS. 2015 Sep;123(9):787-92. doi: 10.1111/apm.12417. Epub 2015 Jul 22.

PMID:
26200697
17.

Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.

Cannon CP, Blazing MA, Giugliano RP, McCagg A, White JA, Theroux P, Darius H, Lewis BS, Ophuis TO, Jukema JW, De Ferrari GM, Ruzyllo W, De Lucca P, Im K, Bohula EA, Reist C, Wiviott SD, Tershakovec AM, Musliner TA, Braunwald E, Califf RM; IMPROVE-IT Investigators.

N Engl J Med. 2015 Jun 18;372(25):2387-97. doi: 10.1056/NEJMoa1410489. Epub 2015 Jun 3.

18.

Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma.

Lauenborg B, Christensen L, Ralfkiaer U, Kopp KL, Jønson L, Dabelsteen S, Bonefeld CM, Geisler C, Gjerdrum LM, Zhang Q, Wasik MA, Ralfkiaer E, Ødum N, Woetmann A.

Oncotarget. 2015 Jun 20;6(17):15235-49.

19.

miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator.

Husby S, Ralfkiaer U, Garde C, Zandi R, Ek S, Kolstad A, Jerkeman M, Laurell A, Räty R, Pedersen LB, Pedersen A, Ehinger M, Sundström C, Karjalainen-Lindsberg ML, Delabie J, Clasen-Linde E, Brown P, Cowland JB, Workman CT, Geisler CH, Grønbæk K.

Blood. 2015 Apr 23;125(17):2669-77. doi: 10.1182/blood-2014-06-584193. Epub 2015 Mar 3.

20.

Development and blind clinical validation of a microRNA based predictor of response to treatment with R-CHO(E)P in DLBCL.

Knudsen S, Hother C, Grønbæk K, Jensen T, Hansen A, Mazin W, Dahlgaard J, Møller MB, Ralfkiær E, Brown Pde N.

PLoS One. 2015 Feb 18;10(2):e0115538. doi: 10.1371/journal.pone.0115538. eCollection 2015.

21.

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma.

Ralfkiaer U, Lindahl LM, Litman T, Gjerdrum LM, Ahler CB, Gniadecki R, Marstrand T, Fredholm S, Iversen L, Wasik MA, Bonefeld CM, Geisler C, Krejsgaard T, Glue C, Røpke MA, Woetmann A, Skov L, Grønbæk K, Odum N.

Anticancer Res. 2014 Dec;34(12):7207-17. Erratum in: Anticancer Res. 2015 Feb;35(2):1219. Lindal, Lise [corrected to Lindahl, Lise M].

PMID:
25503151
22.

Loss of PRDM11 promotes MYC-driven lymphomagenesis.

Fog CK, Asmar F, Côme C, Jensen KT, Johansen JV, Kheir TB, Jacobsen L, Friis C, Louw A, Rosgaard L, Øbro NF, Marquart HV, Anthonsen K, Braat AK, van Lohuizen M, Ralfkiaer E, Grønbæk K, Lund AH.

Blood. 2015 Feb 19;125(8):1272-81. doi: 10.1182/blood-2014-03-560805. Epub 2014 Dec 12.

23.

Ocular adnexal diffuse large B-cell lymphoma: a multicenter international study.

Munch-Petersen HD, Rasmussen PK, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, Khong JJ, McKelvie PA, Mulay K, Prause JU, Ralfkiaer E, Sjö LD, Sniegowski MC, Vemuganti GK, Heegaard S.

JAMA Ophthalmol. 2015 Feb;133(2):165-73. doi: 10.1001/jamaophthalmol.2014.4644.

PMID:
25393033
24.

A short acidic motif in ARF guards against mitochondrial dysfunction and melanoma susceptibility.

Christensen C, Bartkova J, Mistrík M, Hall A, Lange MK, Ralfkiær U, Bartek J, Guldberg P.

Nat Commun. 2014 Nov 5;5:5348. doi: 10.1038/ncomms6348.

PMID:
25370744
25.

[Gelatinous transformation of the bone marrow caused by excessive physical activity and insufficient calorie intake].

Andersen SA, Salomo L, Ralfkiær E, Kjeldsen L.

Ugeskr Laeger. 2014 Sep 15;176(38). pii: V03140183. Review. Danish.

PMID:
25294206
26.

STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides.

Fredholm S, Gjerdrum LM, Willerslev-Olsen A, Petersen DL, Nielsen IØ, Kauczok CS, Wobser M, Ralfkiaer U, Bonefeld CM, Wasik MA, Krejsgaard T, Geisler C, Ralfkiaer E, Gniadecki R, Woetmann A, Odum N.

Anticancer Res. 2014 Oct;34(10):5277-86.

PMID:
25275020
27.

Differential expression of miR-155 and miR-21 in tumor and stroma cells in diffuse large B-cell lymphoma.

Munch-Petersen HD, Ralfkiaer U, Sjö LD, Hother C, Asmar F, Nielsen BS, Brown P, Ralfkiaer E, Grønbæk K.

Appl Immunohistochem Mol Morphol. 2015 Mar;23(3):188-95. doi: 10.1097/PAI.0000000000000073.

PMID:
25265435
28.

Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma.

Kristensen LS, Asmar F, Dimopoulos K, Nygaard MK, Aslan D, Hansen JW, Ralfkiaer E, Grønbæk K.

Oncotarget. 2014 Oct 30;5(20):9798-810.

29.

A dual program for translation regulation in cellular proliferation and differentiation.

Gingold H, Tehler D, Christoffersen NR, Nielsen MM, Asmar F, Kooistra SM, Christophersen NS, Christensen LL, Borre M, Sørensen KD, Andersen LD, Andersen CL, Hulleman E, Wurdinger T, Ralfkiær E, Helin K, Grønbæk K, Ørntoft T, Waszak SM, Dahan O, Pedersen JS, Lund AH, Pilpel Y.

Cell. 2014 Sep 11;158(6):1281-1292. doi: 10.1016/j.cell.2014.08.011.

30.

Ivabradine in stable coronary artery disease without clinical heart failure.

Fox K, Ford I, Steg PG, Tardif JC, Tendera M, Ferrari R; SIGNIFY Investigators.

N Engl J Med. 2014 Sep 18;371(12):1091-9. doi: 10.1056/NEJMoa1406430. Epub 2014 Aug 31.

31.

Follicular lymphoma of the ocular adnexal region: a nation-based study.

Rasmussen PK, Ralfkiaer E, Prause JU, Sjö LD, Specht L, Rossing HH, Siersma VD, Heegaard S.

Acta Ophthalmol. 2015 Mar;93(2):184-91. doi: 10.1111/aos.12525. Epub 2014 Aug 13.

32.

Evaluation of clinical trial eligibility and prognostic indices in a population-based cohort of systemic peripheral T-cell lymphomas from the Danish Lymphoma Registry.

Pedersen MB, Hamilton-Dutoit SJ, Bendix K, Møller MB, Nørgaard P, Johansen P, Ralfkiaer E, Brown Pde N, Hansen PB, Jensen BA, Madsen J, Schöllkopf C, d'Amore F.

Hematol Oncol. 2015 Dec;33(4):120-8. doi: 10.1002/hon.2153. Epub 2014 Jul 23. Erratum in: Hematol Oncol. 2016 Jun;34(2):117.

PMID:
25052551
33.

Effects of extended-release niacin with laropiprant in high-risk patients.

HPS2-THRIVE Collaborative Group, Landray MJ, Haynes R, Hopewell JC, Parish S, Aung T, Tomson J, Wallendszus K, Craig M, Jiang L, Collins R, Armitage J.

N Engl J Med. 2014 Jul 17;371(3):203-12. doi: 10.1056/NEJMoa1300955.

34.

Regulatory T cells in HIV-infected immunological nonresponders are increased in blood but depleted in lymphoid tissue and predict immunological reconstitution.

Gaardbo JC, Hartling HJ, Ronit A, Springborg K, Gjerdrum LM, Ralfkiær E, Thorsteinsson K, Ullum H, Andersen ÅB, Nielsen SD.

J Acquir Immune Defic Syndr. 2014 Aug 1;66(4):349-57. doi: 10.1097/QAI.0000000000000173.

PMID:
24784764
35.

Ocular adnexal follicular lymphoma: a multicenter international study.

Rasmussen PK, Coupland SE, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, McKelvie P, Mulay K, Prause JU, Ralfkiaer E, Sjö LD, Heegaard S.

JAMA Ophthalmol. 2014 Jul;132(7):851-8. doi: 10.1001/jamaophthalmol.2014.376.

PMID:
24763920
36.

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another "double hit" lymphoma with very poor outcome?

Asmar F, Hother C, Kulosman G, Treppendahl MB, Nielsen HM, Ralfkiaer U, Pedersen A, Møller MB, Ralfkiaer E, de Nully Brown P, Grønbæk K.

Oncotarget. 2014 Apr 15;5(7):1912-25.

37.

SOX11 and TP53 add prognostic information to MIPI in a homogenously treated cohort of mantle cell lymphoma--a Nordic Lymphoma Group study.

Nordström L, Sernbo S, Eden P, Grønbaek K, Kolstad A, Räty R, Karjalainen ML, Geisler C, Ralfkiaer E, Sundström C, Laurell A, Delabie J, Ehinger M, Jerkeman M, Ek S.

Br J Haematol. 2014 Jul;166(1):98-108. doi: 10.1111/bjh.12854. Epub 2014 Mar 29.

38.

Nordic MCL3 study: 90Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma.

Kolstad A, Laurell A, Jerkeman M, Grønbæk K, Elonen E, Räty R, Pedersen LB, Loft A, Bogsrud TV, Kimby E, Hansen PB, Fagerli UM, Nilsson-Ehle H, Lauritzsen GF, Lehmann AK, Sundstrom C, Karjalainen-Lindsberg ML, Ralfkiaer E, Ehinger M, Delabie J, Bentzen H, Schildt J, Kostova-Aherdan K, Frederiksen H, Brown Pde N, Geisler CH; Nordic Lymphoma Group.

Blood. 2014 May 8;123(19):2953-9. doi: 10.1182/blood-2013-12-541953. Epub 2014 Mar 20.

39.

Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing.

Kristensen LS, Treppendahl MB, Asmar F, Girkov MS, Nielsen HM, Kjeldsen TE, Ralfkiaer E, Hansen LL, Grønbæk K.

Sci Rep. 2013 Sep 27;3:2789. doi: 10.1038/srep02789.

40.

Expression of miR-155 and miR-126 in situ in cutaneous T-cell lymphoma.

Kopp KL, Ralfkiaer U, Nielsen BS, Gniadecki R, Woetmann A, Ødum N, Ralfkiaer E.

APMIS. 2013 Nov;121(11):1020-4. doi: 10.1111/apm.12162. Epub 2013 Sep 6.

PMID:
24033365
41.

Immunoregulatory T cells may be involved in preserving CD4 T cell counts in HIV-infected long-term nonprogressors and controllers.

Gaardbo JC, Ronit A, Hartling HJ, Gjerdrum LM, Springborg K, Ralfkiær E, Thorsteinsson K, Ullum H, Andersen ÅB, Nielsen SD.

J Acquir Immune Defic Syndr. 2014 Jan 1;65(1):10-8. doi: 10.1097/QAI.0b013e3182a7c932.

PMID:
23995946
42.

World Health Organization-defined classification of myeloproliferative neoplasms: morphological reproducibility and clinical correlations--the Danish experience.

Madelung AB, Bondo H, Stamp I, Loevgreen P, Nielsen SL, Falensteen A, Knudsen H, Ehinger M, Dahl-Sørensen R, Mortensen NB, Svendsen KD, Lange T, Ralfkiaer E, Nielsen K, Hasselbalch HC, Thiele J.

Am J Hematol. 2013 Dec;88(12):1012-6. doi: 10.1002/ajh.23554. Epub 2013 Sep 30.

43.

Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma.

Asmar F, Punj V, Christensen J, Pedersen MT, Pedersen A, Nielsen AB, Hother C, Ralfkiaer U, Brown P, Ralfkiaer E, Helin K, Grønbæk K.

Haematologica. 2013 Dec;98(12):1912-20. doi: 10.3324/haematol.2013.088740. Epub 2013 Jul 5.

44.

MicroRNA profiling in ocular adnexal lymphoma: a role for MYC and NFKB1 mediated dysregulation of microRNA expression in aggressive disease.

Hother C, Rasmussen PK, Joshi T, Reker D, Ralfkiær U, Workman CT, Heegaard S, Ralfkiær E, Grønbæk K.

Invest Ophthalmol Vis Sci. 2013 Aug 5;54(8):5169-75. doi: 10.1167/iovs.13-12272.

PMID:
23821202
45.

Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas.

Marstrand T, Ahler CB, Ralfkiaer U, Clemmensen A, Kopp KL, Sibbesen NA, Krejsgaard T, Litman T, Wasik MA, Bonefeld CM, Grønbæk K, Gjerdum LM, Gniadecki R, Ralfkiaer E, Geisler C, Woetmann A, Røpke MA, Glue C, Skov L, Odum N.

Leuk Lymphoma. 2014 Apr;55(4):957-8. doi: 10.3109/10428194.2013.815352. Epub 2013 Jul 29. No abstract available.

PMID:
23772646
46.

The importance of Notch signaling in peripheral T-cell lymphomas.

Kamstrup MR, Biskup E, Gjerdrum LM, Ralfkiaer E, Niazi O, Gniadecki R.

Leuk Lymphoma. 2014 Mar;55(3):639-44. doi: 10.3109/10428194.2013.807510. Epub 2013 Aug 5.

PMID:
23697875
47.

STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma.

Kopp KL, Ralfkiaer U, Gjerdrum LM, Helvad R, Pedersen IH, Litman T, Jønson L, Hagedorn PH, Krejsgaard T, Gniadecki R, Bonefeld CM, Skov L, Geisler C, Wasik MA, Ralfkiaer E, Ødum N, Woetmann A.

Cell Cycle. 2013 Jun 15;12(12):1939-47. doi: 10.4161/cc.24987. Epub 2013 May 15.

48.

Up-front autologous stem-cell transplantation in peripheral T-cell lymphoma: NLG-T-01.

d'Amore F, Relander T, Lauritzsen GF, Jantunen E, Hagberg H, Anderson H, Holte H, Österborg A, Merup M, Brown P, Kuittinen O, Erlanson M, Østenstad B, Fagerli UM, Gadeberg OV, Sundström C, Delabie J, Ralfkiaer E, Vornanen M, Toldbod HE.

J Clin Oncol. 2012 Sep 1;30(25):3093-9. doi: 10.1200/JCO.2011.40.2719. Epub 2012 Jul 30.

PMID:
22851556
49.

Cryopreserved ovarian cortex from patients with leukemia in complete remission contains no apparent viable malignant cells.

Greve T, Clasen-Linde E, Andersen MT, Andersen MK, Sørensen SD, Rosendahl M, Ralfkiaer E, Andersen CY.

Blood. 2012 Nov 22;120(22):4311-6. doi: 10.1182/blood-2012-01-403022. Epub 2012 Jun 18.

50.

Nordic MCL2 trial update: six-year follow-up after intensive immunochemotherapy for untreated mantle cell lymphoma followed by BEAM or BEAC + autologous stem-cell support: still very long survival but late relapses do occur.

Geisler CH, Kolstad A, Laurell A, Jerkeman M, Räty R, Andersen NS, Pedersen LB, Eriksson M, Nordström M, Kimby E, Bentzen H, Kuittinen O, Lauritzsen GF, Nilsson-Ehle H, Ralfkiaer E, Ehinger M, Sundström C, Delabie J, Karjalainen-Lindsberg ML, Brown P, Elonen E; Nordic Lymphoma Group.

Br J Haematol. 2012 Aug;158(3):355-62. doi: 10.1111/j.1365-2141.2012.09174.x. Epub 2012 May 29. Erratum in: Br J Haematol. 2012 Sep;158(6):815-6.

PMID:
22640180
51.

Diffuse large B-cell lymphoma of the ocular adnexal region: a nation-based study.

Rasmussen PK, Ralfkiaer E, Prause JU, Sjö LD, Toft PB, Siersma VD, Heegaard S.

Acta Ophthalmol. 2013 Mar;91(2):163-9. doi: 10.1111/j.1755-3768.2011.02337.x. Epub 2012 May 2.

52.

A novel immunohistochemical sequential multi-labelling and erasing technique enables epitope characterization of bone marrow pericytes in primary myelofibrosis.

Madelung A, Bzorek M, Bondo H, Zetterberg E, Bjerrum OW, Hasselbalch HC, Scheding S, Ralfkiaer E.

Histopathology. 2012 Mar;60(4):554-60. doi: 10.1111/j.1365-2559.2011.04104.x. Epub 2012 Jan 17.

PMID:
22250648
53.

Malignant lymphoma of the lacrimal gland: a nation-based study.

Rasmussen P, Ralfkiaer E, Prause JU, Sjö LD, Siersma VD, Heegaard S.

Arch Ophthalmol. 2011 Oct;129(10):1275-80. doi: 10.1001/archophthalmol.2011.270.

PMID:
21987669
54.

Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL).

Ralfkiaer U, Hagedorn PH, Bangsgaard N, Løvendorf MB, Ahler CB, Svensson L, Kopp KL, Vennegaard MT, Lauenborg B, Zibert JR, Krejsgaard T, Bonefeld CM, Søkilde R, Gjerdrum LM, Labuda T, Mathiesen AM, Grønbæk K, Wasik MA, Sokolowska-Wojdylo M, Queille-Roussel C, Gniadecki R, Ralfkiaer E, Geisler C, Litman T, Woetmann A, Glue C, Røpke MA, Skov L, Odum N.

Blood. 2011 Nov 24;118(22):5891-900. doi: 10.1182/blood-2011-06-358382. Epub 2011 Aug 24.

55.

Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information.

Edsgärd D, Scheel M, Hansen NT, Ralfkiaer U, Jensen TS, Skakkebaek NE, Brunak S, Gupta R, Rajpert-De Meyts E, Ottesen AM.

Int J Androl. 2011 Aug;34(4 Pt 2):e122-32. doi: 10.1111/j.1365-2605.2011.01188.x. Epub 2011 Jun 22.

PMID:
21696394
56.

The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors.

Hudlebusch HR, Santoni-Rugiu E, Simon R, Ralfkiær E, Rossing HH, Johansen JV, Jørgensen M, Sauter G, Helin K.

Clin Cancer Res. 2011 May 1;17(9):2919-33. doi: 10.1158/1078-0432.CCR-10-1302. Epub 2011 Mar 8.

57.

Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway.

Krejsgaard T, Ralfkiaer U, Clasen-Linde E, Eriksen KW, Kopp KL, Bonefeld CM, Geisler C, Dabelsteen S, Wasik MA, Ralfkiaer E, Woetmann A, Odum N.

J Invest Dermatol. 2011 Jun;131(6):1331-8. doi: 10.1038/jid.2011.27. Epub 2011 Feb 24.

58.

Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome.

Qiu X, Hother C, Ralfkiær UM, Søgaard A, Lu Q, Workman CT, Liang G, Jones PA, Grønbæk K.

PLoS One. 2010 Sep 29;5(9). pii: e12994. doi: 10.1371/journal.pone.0012994.

59.

Integrated genetic and epigenetic analysis of bladder cancer reveals an additive diagnostic value of FGFR3 mutations and hypermethylation events.

Serizawa RR, Ralfkiaer U, Steven K, Lam GW, Schmiedel S, Schüz J, Hansen AB, Horn T, Guldberg P.

Int J Cancer. 2011 Jul 1;129(1):78-87. doi: 10.1002/ijc.25651. Epub 2010 Nov 3.

60.

Lipocalin 2 is protective against E. coli pneumonia.

Wu H, Santoni-Rugiu E, Ralfkiaer E, Porse BT, Moser C, Høiby N, Borregaard N, Cowland JB.

Respir Res. 2010 Jul 15;11:96. doi: 10.1186/1465-9921-11-96.

61.

A novel xenograft model of cutaneous T-cell lymphoma.

Krejsgaard T, Kopp K, Ralfkiaer E, Willumsgaard AE, Eriksen KW, Labuda T, Rasmussen S, Mathiesen AM, Geisler C, Lauenborg B, Becker JC, Zhang Q, Wasik MA, Odum N, Woetmann A.

Exp Dermatol. 2010 Dec;19(12):1096-102. doi: 10.1111/j.1600-0625.2010.01138.x.

PMID:
20629733
62.

Notch1 as a potential therapeutic target in cutaneous T-cell lymphoma.

Kamstrup MR, Gjerdrum LM, Biskup E, Lauenborg BT, Ralfkiaer E, Woetmann A, Ødum N, Gniadecki R.

Blood. 2010 Oct 7;116(14):2504-12. doi: 10.1182/blood-2009-12-260216. Epub 2010 Jun 10.

63.

COX-2-dependent PGE(2) acts as a growth factor in mycosis fungoides (MF).

Kopp KL, Kauczok CS, Lauenborg B, Krejsgaard T, Eriksen KW, Zhang Q, Wasik MA, Geisler C, Ralfkiaer E, Becker JC, Ødum N, Woetmann A.

Leukemia. 2010 Jun;24(6):1179-85. doi: 10.1038/leu.2010.66. Epub 2010 Apr 29.

PMID:
20428208
64.

Custom-designed MLPA using multiple short synthetic probes: application to methylation analysis of five promoter CpG islands in tumor and urine specimens from patients with bladder cancer.

Serizawa RR, Ralfkiaer U, Dahl C, Lam GW, Hansen AB, Steven K, Horn T, Guldberg P.

J Mol Diagn. 2010 Jul;12(4):402-8. doi: 10.2353/jmoldx.2010.090152. Epub 2010 Apr 22.

65.

Evidence of residual disease in cryopreserved ovarian cortex from female patients with leukemia.

Rosendahl M, Andersen MT, Ralfkiær E, Kjeldsen L, Andersen MK, Andersen CY.

Fertil Steril. 2010 Nov;94(6):2186-90. doi: 10.1016/j.fertnstert.2009.11.032. Epub 2010 Jan 25.

PMID:
20100619
66.

The Mantle Cell Lymphoma International Prognostic Index (MIPI) is superior to the International Prognostic Index (IPI) in predicting survival following intensive first-line immunochemotherapy and autologous stem cell transplantation (ASCT).

Geisler CH, Kolstad A, Laurell A, Räty R, Jerkeman M, Eriksson M, Nordström M, Kimby E, Boesen AM, Nilsson-Ehle H, Kuittinen O, Lauritzsen GF, Ralfkiaer E, Ehinger M, Sundström C, Delabie J, Karjalainen-Lindsberg ML, Brown P, Elonen E; Nordic Lymphoma Group.

Blood. 2010 Feb 25;115(8):1530-3. doi: 10.1182/blood-2009-08-236570. Epub 2009 Dec 23.

67.

Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas.

Pedersen IM, Otero D, Kao E, Miletic AV, Hother C, Ralfkiaer E, Rickert RC, Gronbaek K, David M.

EMBO Mol Med. 2009 Aug;1(5):288-95. doi: 10.1002/emmm.200900028.

68.

Improved prognosis for localized malignant lymphomas of the head and neck.

Aanaes K, Kristensen E, Ralfkiaer EM, von Buchwald C, Specht L.

Acta Otolaryngol. 2010 May;130(5):626-31. doi: 10.3109/00016480903311229.

PMID:
19883174
69.

Dabigatran versus warfarin in patients with atrial fibrillation.

Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, Pogue J, Reilly PA, Themeles E, Varrone J, Wang S, Alings M, Xavier D, Zhu J, Diaz R, Lewis BS, Darius H, Diener HC, Joyner CD, Wallentin L; RE-LY Steering Committee and Investigators.

N Engl J Med. 2009 Sep 17;361(12):1139-51. doi: 10.1056/NEJMoa0905561. Epub 2009 Aug 30. Erratum in: N Engl J Med. 2010 Nov 4;363(19):1877.

70.

Ki-67 as a prognostic marker in mantle cell lymphoma-consensus guidelines of the pathology panel of the European MCL Network.

Klapper W, Hoster E, Determann O, Oschlies I, van der Laak J, Berger F, Bernd HW, Cabeçadas J, Campo E, Cogliatti S, Hansmann ML, Kluin PM, Kodet R, Krivolapov YA, Loddenkemper C, Stein H, Möller P, Barth TE, Müller-Hermelink K, Rosenwald A, Ott G, Pileri S, Ralfkiaer E, Rymkiewicz G, van Krieken JH, Wacker HH, Unterhalt M, Hiddemann W, Dreyling M; European MCL Network.

J Hematop. 2009 Jul;2(2):103-11. doi: 10.1007/s12308-009-0036-x. Epub 2009 Jun 16.

71.

Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.

Niemann CU, Cowland JB, Ralfkiaer E, Abrink M, Pejler G, Borregaard N.

Eur J Cell Biol. 2009 Aug;88(8):473-9. doi: 10.1016/j.ejcb.2009.03.002. Epub 2009 May 14.

PMID:
19446360
72.

Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas.

Marquard L, Poulsen CB, Gjerdrum LM, de Nully Brown P, Christensen IJ, Jensen PB, Sehested M, Johansen P, Ralfkiaer E.

Histopathology. 2009 May;54(6):688-98. doi: 10.1111/j.1365-2559.2009.03290.x.

PMID:
19438744
73.

Mantle cell lymphoma in the orbital and adnexal region.

Rasmussen P, Sjö LD, Prause JU, Ralfkiaer E, Heegaard S.

Br J Ophthalmol. 2009 Aug;93(8):1047-51. doi: 10.1136/bjo.2008.146910. Epub 2009 May 7.

PMID:
19429588
74.

Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma.

Krejsgaard T, Vetter-Kauczok CS, Woetmann A, Kneitz H, Eriksen KW, Lovato P, Zhang Q, Wasik MA, Geisler C, Ralfkiaer E, Becker JC, Ødum N.

Blood. 2009 Jun 4;113(23):5896-904. doi: 10.1182/blood-2008-09-181024. Epub 2009 Apr 7.

75.

[Disseminated fusariosis in a patient with acute lymphoblastic leukaemia].

Hermansen NE, Ralfkiaer EM, Kjeldsen L.

Ugeskr Laeger. 2008 Sep 8;170(37):2892. Danish.

PMID:
18796288
76.

Extranodal marginal zone lymphoma in the ocular region: clinical, immunophenotypical, and cytogenetical characteristics.

Sjö LD, Heegaard S, Prause JU, Petersen BL, Pedersen S, Ralfkiaer E.

Invest Ophthalmol Vis Sci. 2009 Feb;50(2):516-22. doi: 10.1167/iovs.08-2539. Epub 2008 Sep 4.

PMID:
18775860
77.

Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome.

Krejsgaard T, Gjerdrum LM, Ralfkiaer E, Lauenborg B, Eriksen KW, Mathiesen AM, Bovin LF, Gniadecki R, Geisler C, Ryder LP, Zhang Q, Wasik MA, Odum N, Woetmann A.

Leukemia. 2008 Dec;22(12):2230-9. doi: 10.1038/leu.2008.224. Epub 2008 Sep 4.

PMID:
18769452
78.

Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial.

Fox K, Ford I, Steg PG, Tendera M, Ferrari R; BEAUTIFUL Investigators.

Lancet. 2008 Sep 6;372(9641):807-16. doi: 10.1016/S0140-6736(08)61170-8. Epub 2008 Aug 29.

PMID:
18757088
79.

Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma.

Marquard L, Gjerdrum LM, Christensen IJ, Jensen PB, Sehested M, Ralfkiaer E.

Histopathology. 2008 Sep;53(3):267-77. doi: 10.1111/j.0309-0167.2008.03109.x.

80.

Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group.

Geisler CH, Kolstad A, Laurell A, Andersen NS, Pedersen LB, Jerkeman M, Eriksson M, Nordström M, Kimby E, Boesen AM, Kuittinen O, Lauritzsen GF, Nilsson-Ehle H, Ralfkiaer E, Akerman M, Ehinger M, Sundström C, Langholm R, Delabie J, Karjalainen-Lindsberg ML, Brown P, Elonen E; Nordic Lymphoma Group.

Blood. 2008 Oct 1;112(7):2687-93. doi: 10.1182/blood-2008-03-147025. Epub 2008 Jul 14.

82.

Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia--a comparative study of four differently designed, high resolution microarray platforms.

Gunnarsson R, Staaf J, Jansson M, Ottesen AM, Göransson H, Liljedahl U, Ralfkiaer U, Mansouri M, Buhl AM, Smedby KE, Hjalgrim H, Syvänen AC, Borg A, Isaksson A, Jurlander J, Juliusson G, Rosenquist R.

Genes Chromosomes Cancer. 2008 Aug;47(8):697-711. doi: 10.1002/gcc.20575.

PMID:
18484635
83.

Increasing incidence of ophthalmic lymphoma in Denmark from 1980 to 2005.

Sjö LD, Ralfkiaer E, Prause JU, Petersen JH, Madsen J, Pedersen NT, Heegaard S.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3283-8. doi: 10.1167/iovs.08-1768. Epub 2008 Apr 4.

PMID:
18390644
84.

FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations.

Gjerdrum LM, Woetmann A, Odum N, Hother C, Henrik-Nielsen R, Gniadecki R, Ralfkiaer E.

Eur J Haematol. 2008 Jun;80(6):483-9. doi: 10.1111/j.1600-0609.2008.01064.x. Epub 2008 Mar 10.

PMID:
18331599
85.

Frequent hypermethylation of DBC1 in malignant lymphoproliferative neoplasms.

Grønbaek K, Ralfkiaer U, Dahl C, Hother C, Burns JS, Kassem M, Worm J, Ralfkiaer EM, Knudsen LM, Hokland P, Guldberg P.

Mod Pathol. 2008 May;21(5):632-8. doi: 10.1038/modpathol.2008.27. Epub 2008 Feb 8.

86.

Potential involvement of Notch1 signalling in the pathogenesis of primary cutaneous CD30-positive lymphoproliferative disorders.

Kamstrup MR, Ralfkiaer E, Skovgaard GL, Gniadecki R.

Br J Dermatol. 2008 Apr;158(4):747-53. doi: 10.1111/j.1365-2133.2007.08427.x. Epub 2008 Jan 30.

PMID:
18241263
87.

Cancer genomics.

Norrild B, Guldberg P, Ralfkiaer E.

APMIS. 2007 Oct;115(10):1037-8.

PMID:
18042142
88.

Genetic and epigenetic alterations of the reduced folate carrier in untreated diffuse large B-cell lymphoma.

Kastrup IB, Worm J, Ralfkiaer E, Hokland P, Guldberg P, Grønbaek K.

Eur J Haematol. 2008 Jan;80(1):61-6. Epub 2007 Nov 19.

PMID:
18028428
89.

Profiling of diffuse large B-cell lymphoma by immunohistochemistry: identification of prognostic subgroups.

Sjö LD, Poulsen CB, Hansen M, Møller MB, Ralfkiaer E.

Eur J Haematol. 2007 Dec;79(6):501-7. Epub 2007 Nov 7.

PMID:
17986209
90.

Serglycin proteoglycan in hematologic malignancies: a marker of acute myeloid leukemia.

Niemann CU, Kjeldsen L, Ralfkiaer E, Jensen MK, Borregaard N.

Leukemia. 2007 Dec;21(12):2406-10. Epub 2007 Oct 11.

PMID:
17928883
91.

FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival.

Gjerdrum LM, Woetmann A, Odum N, Burton CM, Rossen K, Skovgaard GL, Ryder LP, Ralfkiaer E.

Leukemia. 2007 Dec;21(12):2512-8. Epub 2007 Aug 23.

PMID:
17713545
92.

Cigarette smoking and risk of Hodgkin lymphoma: a population-based case-control study.

Hjalgrim H, Ekström-Smedby K, Rostgaard K, Amini RM, Molin D, Hamilton-Dutoit S, Schöllkopf C, Chang ET, Ralfkiaer E, Adami HO, Glimelius B, Melbye M.

Cancer Epidemiol Biomarkers Prev. 2007 Aug;16(8):1561-6.

93.

Infectious mononucleosis, childhood social environment, and risk of Hodgkin lymphoma.

Hjalgrim H, Smedby KE, Rostgaard K, Molin D, Hamilton-Dutoit S, Chang ET, Ralfkiaer E, Sundström C, Adami HO, Glimelius B, Melbye M.

Cancer Res. 2007 Mar 1;67(5):2382-8.

94.

Role of Helicobacter pylori in conjunctival mucosa-associated lymphoid tissue lymphoma.

Sjö NC, Foegh P, Juhl BR, Nilsson HO, Prause JU, Ralfkiaer E, Wadström T, Heegaard S.

Ophthalmology. 2007 Jan;114(1):182-6.

PMID:
17198854
95.

Methods for detection of subtle mutations in cancer genomes.

Dahl C, Ralfkiaer U, Guldberg P.

Crit Rev Oncog. 2006 Jul;12(1-2):41-74. Review.

PMID:
17078206
96.

Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator.

Juncker-Jensen A, Lykkesfeldt AE, Worm J, Ralfkiaer U, Espelund U, Jepsen JS.

Growth Horm IGF Res. 2006 Aug;16(4):224-39. Epub 2006 Aug 8.

PMID:
16893667
97.

Prognostic significance of metallothionein in B-cell lymphomas.

Poulsen CB, Borup R, Borregaard N, Nielsen FC, Møller MB, Ralfkiaer E.

Blood. 2006 Nov 15;108(10):3514-9. Epub 2006 Jul 25.

98.

Different histopathological subtypes of Hodgkin lymphoma show significantly different levels of FDG uptake.

Hutchings M, Loft A, Hansen M, Ralfkiaer E, Specht L.

Hematol Oncol. 2006 Sep;24(3):146-50.

PMID:
16729353
99.

Primary lymphoma of the lacrimal sac: an EORTC ophthalmic oncology task force study.

Sjö LD, Ralfkiaer E, Juhl BR, Prause JU, Kivelä T, Auw-Haedrich C, Bacin F, Carrera M, Coupland SE, Delbosc B, Ducrey N, Kantelip B, Kemeny JL, Meyer P, Sjö NC, Heegaard S; European Organization for Research and Treatment of Cancer.

Br J Ophthalmol. 2006 Aug;90(8):1004-9. Epub 2006 May 3.

100.

Epstein-Barr positive T-cell lymphoma in the ocular region.

Sjö LD, Juhl BR, Buchwald C, Prause JU, Ralfkiaer E, Sjö NC, Heegaard S.

Eur J Ophthalmol. 2006 Jan-Feb;16(1):181-5.

PMID:
16496268
101.

WHO/EORTC classification of cutaneous lymphomas 2005: histological and molecular aspects.

Burg G, Kempf W, Cozzio A, Feit J, Willemze R, S Jaffe E, Dummer R, Berti E, Cerroni L, Chimenti S, Diaz-Perez JL, Grange F, Harris NL, Kazakov DV, Kerl H, Kurrer M, Knobler R, Meijer CJ, Pimpinelli N, Ralfkiaer E, Russell-Jones R, Sander C, Santucci M, Sterry W, Swerdlow SH, Vermeer MH, Wechsler J, Whittaker S.

J Cutan Pathol. 2005 Nov;32(10):647-74. Review.

PMID:
16293178
102.

Microarray-based classification of diffuse large B-cell lymphoma.

Poulsen CB, Borup R, Nielsen FC, Borregaard N, Hansen M, Grønbaek K, Møller MB, Ralfkiaer E.

Eur J Haematol. 2005 Jun;74(6):453-65.

PMID:
15876249
103.

WHO-EORTC classification for cutaneous lymphomas.

Willemze R, Jaffe ES, Burg G, Cerroni L, Berti E, Swerdlow SH, Ralfkiaer E, Chimenti S, Diaz-Perez JL, Duncan LM, Grange F, Harris NL, Kempf W, Kerl H, Kurrer M, Knobler R, Pimpinelli N, Sander C, Santucci M, Sterry W, Vermeer MH, Wechsler J, Whittaker S, Meijer CJ.

Blood. 2005 May 15;105(10):3768-85. Epub 2005 Feb 3. Review.

104.

Towards discovery-driven translational research in breast cancer.

Celis JE, Moreira JM, Gromova I, Cabezon T, Ralfkiaer U, Guldberg P, Straten PT, Mouridsen H, Friis E, Holm D, Rank F, Gromov P.

FEBS J. 2005 Jan;272(1):2-15. Review.

105.

HLA-B35-restricted immune responses against survivin in cancer patients.

Reker S, Becker JC, Svane IM, Ralfkiaer E, Straten PT, Andersen MH.

Int J Cancer. 2004 Mar 1;108(6):937-41.

106.

Imatinib mesylate in idiopathic and postpolycythemic myelofibrosis.

Hasselbalch HC, Bjerrum OW, Jensen BA, Clausen NT, Hansen PB, Birgens H, Therkildsen MH, Ralfkiaer E.

Am J Hematol. 2003 Dec;74(4):238-42.

107.

Infrequent somatic Fas mutations but no evidence of Bcl10 mutations or t(11;18) in primary cutaneous MALT-type lymphoma.

Grønbaek K, Ralfkiaer E, Kalla J, Skovgaard GL, Guldberg P.

J Pathol. 2003 Sep;201(1):134-40.

PMID:
12950026
108.

Primary treatment with autologous stem cell transplantation in mantle cell lymphoma: outcome related to remission pretransplant.

Andersen NS, Pedersen L, Elonen E, Johnson A, Kolstad A, Franssila K, Langholm R, Ralfkiaer E, Akerman M, Eriksson M, Kuittinen O, Geisler CH; Nordic Lymphoma Group.

Eur J Haematol. 2003 Aug;71(2):73-80.

PMID:
12890145
109.

[Molecular biology diagnostics: malignant lymphoid tumors in adults].

Poulsen CB, Ralfkiaer EM, Borregaard N, Grønboek K.

Ugeskr Laeger. 2003 Feb 24;165(9):901-5. Review. Danish.

PMID:
12661512
110.

ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma.

Grønbaek K, Worm J, Ralfkiaer E, Ahrenkiel V, Hokland P, Guldberg P.

Blood. 2002 Aug 15;100(4):1430-7.

111.

Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases.

Pileri SA, Grogan TM, Harris NL, Banks P, Campo E, Chan JK, Favera RD, Delsol G, De Wolf-Peeters C, Falini B, Gascoyne RD, Gaulard P, Gatter KC, Isaacson PG, Jaffe ES, Kluin P, Knowles DM, Mason DY, Mori S, Müller-Hermelink HK, Piris MA, Ralfkiaer E, Stein H, Su IJ, Warnke RA, Weiss LM.

Histopathology. 2002 Jul;41(1):1-29.

PMID:
12121233
112.

A case of lymphoblastoid natural killer (NK)-cell lymphoma: association with the NK-cell receptor complex CD94/NKG2 and TP53 intragenic deletion.

Knudsen H, Grønbaek K, thor Straten P, Gisselø C, Johansen P, Timshel S, Bergmann OJ, Hansen NE, Ralfkiaer E.

Br J Dermatol. 2002 Jan;146(1):148-53.

PMID:
11841384
113.

Cancer cell expression of urokinase-type plasminogen activator receptor mRNA in squamous cell carcinomas of the skin.

Rømer J, Pyke C, Lund LR, Ralfkiaer E, Danø K.

J Invest Dermatol. 2001 Mar;116(3):353-8.

114.

The V410I (G1228A) variant of the caspase-10 gene is a common polymorphism of the Danish population.

Grønbaek K, Dalby T, Zeuthen J, Ralfkiaer E, Guidberg P.

Blood. 2000 Mar 15;95(6):2184-5. No abstract available.

115.

Concurrent disruption of p16INK4a and the ARF-p53 pathway predicts poor prognosis in aggressive non-Hodgkin's lymphoma.

Grønbaek K, de Nully Brown P, Møller MB, Nedergaard T, Ralfkiaer E, Møller P, Zeuthen J, Guldberg P.

Leukemia. 2000 Oct;14(10):1727-35.

PMID:
11021747
116.

Primary cutaneous B-cell lymphoma: a clinical, histological, phenotypic and genotypic study of 21 cases.

Grønbaek K, Møller PH, Nedergaard T, Thomsen K, Baadsgaard O, Hou-Jensen K, Zeuthen J, Guldberg P, Ralfkiaer E.

Br J Dermatol. 2000 May;142(5):913-23.

PMID:
10809848
117.

Fatal rupture of the spleen caused by infiltration of T-cell lymphoma.

Schiødt I, Duun E, Fischer TK, Christiansen AP, Ralfkiaer E.

Ann Hematol. 2000 Mar;79(3):158-60.

PMID:
10803939
118.

Apoptosis-related genes and proteins in Hodgkin's disease.

Lauritzen AF, Møller PH, Nedergaard T, Guldberg P, Hou-Jensen K, Ralfkiaer E.

APMIS. 1999 Jul;107(7):636-44.

PMID:
10440059
119.

Co-expression of CD79a (JCB117) and CD3 by lymphoblastic lymphoma.

Pilozzi E, Pulford K, Jones M, Müller-Hermelink HK, Falini B, Ralfkiaer E, Pileri S, Pezzella F, De Wolf-Peeters C, Arber D, Stein H, Mason D, Gatter K.

J Pathol. 1998 Oct;186(2):140-3.

PMID:
9924428
120.

Somatic Fas mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity.

Grønbaek K, Straten PT, Ralfkiaer E, Ahrenkiel V, Andersen MK, Hansen NE, Zeuthen J, Hou-Jensen K, Guldberg P.

Blood. 1998 Nov 1;92(9):3018-24.

121.

Primary gastrointestinal non-Hodgkin's lymphoma in adults: a population-based clinical and histopathologic study.

Hansen PB, Vogt KC, Skov RL, Pedersen-Bjergaard U, Jacobsen M, Ralfkiaer E.

J Intern Med. 1998 Jul;244(1):71-8.

122.

Concurrent disruption of cell cycle associated genes in mantle cell lymphoma: a genotypic and phenotypic study of cyclin D1, p16, p15, p53 and pRb.

Grønbaek K, Nedergaard T, Andersen MK, thor Straten P, Guldberg P, Møller P, Zeuthen J, Ebbe Hansen N, Hou-Jensen K, Ralfkiaer E.

Leukemia. 1998 Aug;12(8):1266-71.

PMID:
9697882
123.

Changing bone marrow micro-environment during development of acute myeloid leukaemia in rats.

Mortensen BT, Jensen PO, Helledie N, Iversen PO, Ralfkiaer E, Larsen JK, Madsen MT.

Br J Haematol. 1998 Jul;102(2):458-64.

PMID:
9695960
124.

Alterations of the MMAC1/PTEN gene in lymphoid malignancies.

Grønbaek K, Zeuthen J, Guldberg P, Ralfkiaer E, Hou-Jensen K.

Blood. 1998 Jun 1;91(11):4388-90. No abstract available.

125.

T-cell receptor variable region genes in cutaneous T-cell lymphomas.

Thor Straten P, Ralfkiaer E, Hendriks J, Seremet T, Vejlsgaard GL, Zeuthen J.

Br J Dermatol. 1998 Jan;138(1):3-12.

PMID:
9536217
126.

EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer.

Willemze R, Kerl H, Sterry W, Berti E, Cerroni L, Chimenti S, Diaz-Peréz JL, Geerts ML, Goos M, Knobler R, Ralfkiaer E, Santucci M, Smith N, Wechsler J, van Vloten WA, Meijer CJ.

Blood. 1997 Jul 1;90(1):354-71. Review.

127.

CD34+ megakaryoblastic leukaemic cells are CD38-, but CD61+ and glycophorin A+: improved criteria for diagnosis of AML-M7?

Helleberg C, Knudsen H, Hansen PB, Nikolajsen K, Kjaersgaard E, Ralfkiaer E, Johnsen HE.

Leukemia. 1997 Jun;11(6):830-4.

PMID:
9177436
130.

An immunohistochemical study of TAL-1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL 242.

Chetty R, Pulford K, Jones M, Mathieu-Mahul D, Close P, Hussein S, Pallesen G, Ralfkiaer E, Stein H, Gatter K, Mason D.

J Pathol. 1996 Mar;178(3):311-5.

PMID:
8778337
131.
132.

A novel antigen detected by the CBF.78 antibody further distinguishes anaplastic large cell lymphoma from Hodgkin's disease.

al Saati T, Tkaczuk J, Krissansen G, Print C, Pileri S, Ralfkiaer E, Grogan TM, Meggetto F, Delsol G.

Blood. 1995 Oct 1;86(7):2741-6.

134.
135.

SCL/Tal-1 expression in T-acute lymphoblastic leukemia: an immunohistochemical and genotypic study.

Chetty R, Pulford K, Jones M, Mathieu-Mahul D, Close P, Hussein S, Pallesen G, Ralfkiaer E, Stein H, Gatter K, et al.

Hum Pathol. 1995 Sep;26(9):994-8.

PMID:
7672800
136.

Production and characterisation of an antimelanoma monoclonal antibody KBA.62 using a new melanoma cell line reactive on paraffin wax embedded sections.

Cohen-Knafo E, al Saati T, Aziza J, Ralfkiaer E, Selves J, Gorguet B, Delsol G.

J Clin Pathol. 1995 Sep;48(9):826-31.

137.

CD79a: a novel marker for B-cell neoplasms in routinely processed tissue samples.

Mason DY, Cordell JL, Brown MH, Borst J, Jones M, Pulford K, Jaffe E, Ralfkiaer E, Dallenbach F, Stein H, et al.

Blood. 1995 Aug 15;86(4):1453-9.

138.

p53 protein expression in cutaneous T-cell lymphomas.

Lauritzen AF, Vejlsgaard GL, Hou-Jensen K, Ralfkiaer E.

Br J Dermatol. 1995 Jul;133(1):32-6.

PMID:
7669637
139.

Histiocytic sarcomas.

Lauritzen AF, Ralfkiaer E.

Leuk Lymphoma. 1995 Jun;18(1-2):73-80. Review.

PMID:
8580832
140.

Priming and treatment with molgramostim (rhGM-CSF) in adult high-risk acute myeloid leukemia during induction chemotherapy: a prospective, randomized pilot study.

Hansen PB, Johnsen HE, Jensen L, Gaarsdal E, Simonsen K, Ralfkiaer E.

Eur J Haematol. 1995 May;54(5):296-303.

PMID:
7540147
141.
142.

Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue.

Plesner T, Ralfkiaer E, Wittrup M, Johnsen H, Pyke C, Pedersen TL, Hansen NE, Danø K.

Am J Clin Pathol. 1994 Dec;102(6):835-41.

PMID:
7801901
143.

The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers.

Pyke C, Rømer J, Kallunki P, Lund LR, Ralfkiaer E, Danø K, Tryggvason K.

Am J Pathol. 1994 Oct;145(4):782-91.

144.

Histiocytic sarcomas and monoblastic leukemias. A clinical, histologic, and immunophenotypical study.

Lauritzen AF, Delsol G, Hansen NE, Horn T, Ersbøll J, Hou-Jensen K, Ralfkiaer E.

Am J Clin Pathol. 1994 Jul;102(1):45-54.

PMID:
8037167
145.

Controversies and discussion on early diagnosis of cutaneous T-cell lymphoma. Phenotyping.

Ralfkiaer E.

Dermatol Clin. 1994 Apr;12(2):329-34. Review.

PMID:
8045044
146.

Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer.

Pyke C, Ralfkiaer E, Rønne E, Høyer-Hansen G, Kirkeby L, Danø K.

Histopathology. 1994 Feb;24(2):131-8.

PMID:
8181805
147.

Immunophenotypic studies in cutaneous T-cell lymphomas: clinical implications.

Ralfkiaer E, Wollf-Sneedorff A, Thomsen K, Vejlsgaard GL.

Br J Dermatol. 1993 Dec;129(6):655-9.

PMID:
8286247
148.
149.

P53 protein expression in Hodgkin's disease.

Lauritzen AF, Hou-Jensen K, Ralfkiaer E.

APMIS. 1993 Sep;101(9):689-94.

PMID:
8240788
151.

Receptor for urokinase is present in tumor-associated macrophages in ductal breast carcinoma.

Pyke C, Graem N, Ralfkiaer E, Rønne E, Høyer-Hansen G, Brünner N, Danø K.

Cancer Res. 1993 Apr 15;53(8):1911-5.

152.

Heterogeneity of CD3 antigen expression in T-cell lymphoma.

Wood KM, Pallesen G, Ralfkiaer E, Warnke R, Gatter KC, Mason DY.

Histopathology. 1993 Apr;22(4):311-7.

PMID:
8514274
153.

Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.

Pyke C, Ralfkiaer E, Tryggvason K, Danø K.

Am J Pathol. 1993 Feb;142(2):359-65.

154.

Hairy cell leukemia. Diagnosis of bone marrow involvement in paraffin-embedded sections with monoclonal antibody DBA.44.

Hounieu H, Chittal SM, al Saati T, de Mascarel A, Sabattini E, Pileri S, Falini B, Ralfkiaer E, Le Tourneau A, Selves J, et al.

Am J Clin Pathol. 1992 Jul;98(1):26-33.

PMID:
1615922
155.

T-cell receptor gamma delta-positive peripheral T-cell lymphomas presenting in the skin: a clinical, histological and immunophenotypic study.

Ralfkiaer E, Wollf-Sneedorff A, Thomsen K, Geisler C, Vejlsgaard GL.

Exp Dermatol. 1992 Jul;1(1):31-6.

PMID:
1344658
156.

Tumours classified as "malignant histiocytosis" in children are T-cell neoplasms.

Ornvold K, Carstensen H, Junge J, Gyhrs A, Ralfkiaer E.

APMIS. 1992 Jun;100(6):558-66.

PMID:
1319178
157.

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.

Pyke C, Ralfkiaer E, Huhtala P, Hurskainen T, Danø K, Tryggvason K.

Cancer Res. 1992 Mar 1;52(5):1336-41.

158.

Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma.

Pezzella F, Jones M, Ralfkiaer E, Ersbøll J, Gatter KC, Mason DY.

Br J Cancer. 1992 Jan;65(1):87-9.

159.

Expression of Epstein-Barr virus replicative proteins in AIDS-related non-Hodgkin's lymphoma cells.

Pallesen G, Hamilton-Dutoit SJ, Rowe M, Lisse I, Ralfkiaer E, Sandvej K, Young LS.

J Pathol. 1991 Dec;165(4):289-99.

PMID:
1664459
160.

Expression of mutant p53 in melanoma.

Stretch JR, Gatter KC, Ralfkiaer E, Lane DP, Harris AL.

Cancer Res. 1991 Nov 1;51(21):5976-9.

161.

Differential expression of urokinase-type plasminogen activator and its type-1 inhibitor during healing of mouse skin wounds.

Rømer J, Lund LR, Eriksen J, Ralfkiaer E, Zeheb R, Gelehrter TD, Danø K, Kristensen P.

J Invest Dermatol. 1991 Nov;97(5):803-11.

162.
163.
164.
165.

Antibody BNH9 detects red blood cell-related antigens on anaplastic large cell (CD30+) lymphomas.

Delsol G, Blancher A, al Saati T, Ralfkiaer E, Lauritzen A, Bruigères L, Brousset P, Rigal-Huguet F, Mazerolles C, Robert A, et al.

Br J Cancer. 1991 Aug;64(2):321-6.

166.
167.

Expression of a cell adhesion protein (VLA beta) in normal and diseased skin.

Ralfkiaer E, Thomsen K, Vejlsgaard GL.

Br J Dermatol. 1991 Jun;124(6):527-32.

PMID:
1712220
168.

Immunohistological markers for the diagnosis of cutaneous lymphomas.

Ralfkiaer E.

Semin Diagn Pathol. 1991 May;8(2):62-72. Review. No abstract available.

PMID:
1871451
169.

Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas.

Pyke C, Kristensen P, Ralfkiaer E, Grøndahl-Hansen J, Eriksen J, Blasi F, Danø K.

Am J Pathol. 1991 May;138(5):1059-67.

170.

Peripheral T-cell lymphomas: an evaluation of reproducibility of the updated Kiel classification.

Hastrup N, Hamilton-Dutoit S, Ralfkiaer E, Pallesen G.

Histopathology. 1991 Feb;18(2):99-105.

PMID:
2010191
171.

Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans.

Grøndahl-Hansen J, Ralfkiaer E, Kirkeby LT, Kristensen P, Lund LR, Danø K.

Am J Pathol. 1991 Jan;138(1):111-7.

172.

Expression of intercellular adhesion molecule-1 (ICAM-1) in benign naevi and malignant melanomas.

Hansen NL, Ralfkiaer E, Hou-Jensen K, Thomsen K, Drzewiecki KT, Rothlein R, Vejlsgaard GL.

Acta Derm Venereol. 1991;71(1):48-51.

PMID:
1676215
173.

HIV-associated lymphoma: histopathology and association with Epstein-Barr virus genome related to clinical, immunological and prognostic features.

Pedersen C, Gerstoft J, Lundgren JD, Skinhøj P, Bøttzauw J, Geisler C, Hamilton-Dutoit SJ, Thorsen S, Lisse I, Ralfkiaer E, et al.

Eur J Cancer. 1991;27(11):1416-23.

PMID:
1660293
174.

The 14;18 translocation in European cases of follicular lymphoma: comparison of Southern blotting and the polymerase chain reaction.

Pezzella F, Ralfkiaer E, Gatter KC, Mason DY.

Br J Haematol. 1990 Sep;76(1):58-64. Review.

PMID:
2223649
175.

Flow cytometric DNA analysis of lesions from 18 children with langerhans cell histiocytosis (histiocytosis x).

Ornvold K, Carstensen H, Larsen JK, Christensen IJ, Ralfkiaer E.

Am J Pathol. 1990 Jun;136(6):1301-7.

176.

Malignant lymphomas of true histiocytic origin. A clinical, histological, immunophenotypic and genotypic study.

Ralfkiaer E, Delsol G, O'Connor NT, Brandtzaeg P, Brousset P, Vejlsgaard GL, Mason DY.

J Pathol. 1990 Jan;160(1):9-17.

PMID:
2156039
177.

Immunohistochemical study of the abnormal cells in Langerhans cell histiocytosis (histiocytosis x).

Ornvold K, Ralfkiaer E, Carstensen H.

Virchows Arch A Pathol Anat Histopathol. 1990;416(5):403-10.

PMID:
2107627
178.

Leukocyte adhesion.

Hansen NL, Rothlein R, Ralfkiaer E, Vejlsgaard GL.

Curr Probl Dermatol. 1990;19:17-28. Review. No abstract available.

PMID:
1967571
179.

Keratinocyte and epidermal leukocyte expression of CD36 (OKM5) in benign and malignant skin diseases.

Lisby S, Ralfkiaer E, Hansen ER, Vejlsgaard GL.

Acta Derm Venereol. 1990;70(1):18-22.

PMID:
1689091
180.

Diagnosis of myelomonocytic and macrophage neoplasms in routinely processed tissue biopsies with monoclonal antibody KP1.

Warnke RA, Pulford KA, Pallesen G, Ralfkiaer E, Brown DC, Gatter KC, Mason DY.

Am J Pathol. 1989 Dec;135(6):1089-95.

181.

Autoimmune involvement in Cushing syndrome due to primary adrenocortical nodular dysplasia.

Carstensen H, Krabbe S, Wulffraat NM, Nielsen MD, Ralfkiaer E, Drexhage HA.

Eur J Pediatr. 1989 Nov;149(2):84-7.

PMID:
2591414
182.

Detection of T cells in paraffin wax embedded tissue using antibodies against a peptide sequence from the CD3 antigen.

Mason DY, Cordell J, Brown M, Pallesen G, Ralfkiaer E, Rothbard J, Crumpton M, Gatter KC.

J Clin Pathol. 1989 Nov;42(11):1194-200.

183.

Urokinase-type plasminogen activator in endothelial cells during acute inflammation of the appendix.

Grøndahl-Hansen J, Kirkeby LT, Ralfkiaer E, Kristensen P, Lund LR, Danø K.

Am J Pathol. 1989 Oct;135(4):631-6.

184.

Diagnosis of acute myeloid leukaemia with the use of monoclonal anti-neutrophil elastase (NP57) reactive with routinely processed biopsy samples.

Ralfkiaer E, Pulford KA, Lauritzen AF, Avnstrøm S, Guldhammer B, Mason DY.

Histopathology. 1989 Jun;14(6):637-43.

PMID:
2759560
185.

DNA analysis by flow cytometry in cutaneous T-cell lymphomas.

Ralfkiaer E, Larsen JK, Christensen IJ, Thomsen K, Wantzin GL.

Br J Dermatol. 1989 May;120(5):597-605.

PMID:
2788008
186.

Fatal cutaneous T cell lymphoma in a child with atopic dermatitis.

Lange-Vejlsgaard G, Ralfkiaer E, Larsen JK, O'Connor N, Thomsen K.

J Am Acad Dermatol. 1989 May;20(5 Pt 2):954-8.

PMID:
2785543
187.

Kinetics and characterization of intercellular adhesion molecule-1 (ICAM-1) expression on keratinocytes in various inflammatory skin lesions and malignant cutaneous lymphomas.

Vejlsgaard GL, Ralfkiaer E, Avnstorp C, Czajkowski M, Marlin SD, Rothlein R.

J Am Acad Dermatol. 1989 May;20(5 Pt 1):782-90.

PMID:
2654218
188.

Intercellular adhesion molecule-I (ICAM-I) expression correlated to inflammation.

Lisby S, Ralfkiaer E, Rothlein R, Vejlsgaard GL.

Br J Dermatol. 1989 Apr;120(4):479-84.

PMID:
2471544
189.

Aberrant phenotypes in peripheral T cell lymphomas.

Hastrup N, Ralfkiaer E, Pallesen G.

J Clin Pathol. 1989 Apr;42(4):398-402.

190.

The development of a Ki-1-positive large cell non-Hodgkin's lymphoma in pagetoid reticulosis.

Ralfkiaer E, Thomsen K, Agdal N, Hou-Jensen K, Wantzin GL.

Acta Derm Venereol. 1989;69(3):206-11.

PMID:
2566223
191.

Evolution of cutaneous lymphoid hyperplasia to cutaneous T-cell lymphoma.

Wantzin GL, Thomsen K, Ralfkiaer E.

Clin Exp Dermatol. 1988 Sep;13(5):309-13. No abstract available.

PMID:
3267178
192.

High-risk AML evidenced by a monoclonal antibody.

Avnstrøm S, Ralfkiaer E, Hansen NE, Nissen NI.

Eur J Haematol. 1988 Aug;41(2):156-62.

PMID:
3165866
193.

The role of intercellular adhesion molecules in inflammatory skin reactions.

Lange Wantzin G, Ralfkiaer E, Lisby S, Rothlein R.

Br J Dermatol. 1988 Aug;119(2):141-5. Review. No abstract available.

PMID:
2458751
194.

Urokinase- and tissue-type plasminogen activators in keratinocytes during wound reepithelialization in vivo.

Grøndahl-Hansen J, Lund LR, Ralfkiaer E, Ottevanger V, Danø K.

J Invest Dermatol. 1988 Jun;90(6):790-5.

196.

Immunophenotyping of non-Hodgkin's lymphomas using a panel of antibodies on paraffin-embedded tissues.

Davey FR, Gatter KC, Ralfkiaer E, Pulford KA, Krissansen GW, Mason DY.

Am J Pathol. 1987 Oct;129(1):54-63. Erratum in: Am J Pathol 1988 Jan;130(1):9.

197.

Prognostic relevance of tumour-cell growth fraction in malignant non-Hodgkin's lymphomas.

Gerdes J, Stein H, Pileri S, Rivano MT, Gobbi M, Ralfkiaer E, Nielsen KM, Pallesen G, Bartels H, Palestro G, et al.

Lancet. 1987 Aug 22;2(8556):448-9. No abstract available. Erratum in: Lancet 1987 Sep 26;2(8561):756.

PMID:
2887743
198.

Genotypic analysis of cutaneous T-cell lymphomas.

Ralfkiaer E, O'Connor NT, Crick J, Wantzin GL, Mason DY.

J Invest Dermatol. 1987 Jun;88(6):762-5.

199.

Sequential immunophenotypic study of lymphoid infiltrate in allergic and irritant reactions.

Avnstorp C, Ralfkiaer E, Jørgensen J, Wantzin GL.

Contact Dermatitis. 1987 May;16(5):239-45.

PMID:
3497775
200.

Value of monoclonal anti-CD22 (p135) antibodies for the detection of normal and neoplastic B lymphoid cells.

Mason DY, Stein H, Gerdes J, Pulford KA, Ralfkiaer E, Falini B, Erber WN, Micklem K, Gatter KC.

Blood. 1987 Mar;69(3):836-40.

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