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Items: 88

1.

Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment.

Lauridsen FKB, Jensen TL, Rapin N, Aslan D, Wilhelmson AS, Pundhir S, Rehn M, Paul F, Giladi A, Hasemann MS, Serup P, Amit I, Porse BT.

Cell Rep. 2018 Jul 17;24(3):766-780. doi: 10.1016/j.celrep.2018.06.057.

2.

Leukemogenic nucleophosmin mutation disrupts the transcription factor hub regulating granulo-monocytic fates.

Gu X, Ebrahem Q, Mahfouz RZ, Hasipek M, Enane F, Radivoyevitch T, Rapin N, Przychodzen B, Hu Z, Balusu R, Cotta CV, Wald D, Argueta C, Landesman Y, Martelli MP, Falini B, Carraway H, Porse BT, Maciejewski JP, Jha BK, Saunthararajah Y.

J Clin Invest. 2018 Jul 17. pii: 97117. doi: 10.1172/JCI97117. [Epub ahead of print]

3.

A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines.

Martin Gonzalez J, Baudet A, Abelechian S, Bonderup K, d'Altri T, Porse B, Brakebusch C, Juliusson G, Cammenga J.

Genesis. 2018 Jul 16. doi: 10.1002/dvg.23238. [Epub ahead of print]

PMID:
30010246
4.

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.

Reckzeh K, Kizilkaya H, Helbo AS, Alrich ME, Deslauriers AG, Grover A, Rapin N, Asmar F, Grønbæk K, Porse B, Borregaard N, Vestweber D, Nerlov C, Theilgaard-Mönch K.

Blood Adv. 2018 Jul 10;2(13):1628-1632. doi: 10.1182/bloodadvances.2018015743. No abstract available.

5.

Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors.

Pundhir S, Bratt Lauridsen FK, Schuster MB, Jakobsen JS, Ge Y, Schoof EM, Rapin N, Waage J, Hasemann MS, Porse BT.

Cell Rep. 2018 May 29;23(9):2744-2757. doi: 10.1016/j.celrep.2018.05.012.

6.

Testosterone is an endogenous regulator of BAFF and splenic B cell number.

Wilhelmson AS, Lantero Rodriguez M, Stubelius A, Fogelstrand P, Johansson I, Buechler MB, Lianoglou S, Kapoor VN, Johansson ME, Fagman JB, Duhlin A, Tripathi P, Camponeschi A, Porse BT, Rolink AG, Nissbrandt H, Turley SJ, Carlsten H, Mårtensson IL, Karlsson MCI, Tivesten Å.

Nat Commun. 2018 May 25;9(1):2067. doi: 10.1038/s41467-018-04408-0.

7.

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.

Mohammad F, Weissmann S, Leblanc B, Pandey DP, Højfeldt JW, Comet I, Zheng C, Johansen JV, Rapin N, Porse BT, Tvardovskiy A, Jensen ON, Olaciregui NG, Lavarino C, Suñol M, de Torres C, Mora J, Carcaboso AM, Helin K.

Nat Med. 2017 Apr;23(4):483-492. doi: 10.1038/nm.4293. Epub 2017 Feb 27.

PMID:
28263309
8.

The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery.

Stunnenberg HG; International Human Epigenome Consortium, Hirst M.

Cell. 2016 Nov 17;167(5):1145-1149. doi: 10.1016/j.cell.2016.11.007. Erratum in: Cell. 2016 Dec 15;167(7):1897.

9.

UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts.

Bao J, Vitting-Seerup K, Waage J, Tang C, Ge Y, Porse BT, Yan W.

PLoS Genet. 2016 May 5;12(5):e1005863. doi: 10.1371/journal.pgen.1005863. eCollection 2016 May.

10.

Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality.

Pundhir S, Bagger FO, Lauridsen FB, Rapin N, Porse BT.

Nucleic Acids Res. 2016 May 19;44(9):4037-51. doi: 10.1093/nar/gkw250. Epub 2016 Apr 19.

11.

The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia.

O'Connor C, Lohan F, Campos J, Ohlsson E, Salomè M, Forde C, Artschwager R, Liskamp RM, Cahill MR, Kiely PA, Porse B, Keeshan K.

Oncogene. 2016 Oct 6;35(40):5272-5281. doi: 10.1038/onc.2016.66. Epub 2016 Mar 21.

PMID:
26996668
12.

C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4.

Di Stefano B, Collombet S, Jakobsen JS, Wierer M, Sardina JL, Lackner A, Stadhouders R, Segura-Morales C, Francesconi M, Limone F, Mann M, Porse B, Thieffry D, Graf T.

Nat Cell Biol. 2016 Apr;18(4):371-81. doi: 10.1038/ncb3326. Epub 2016 Mar 14.

PMID:
26974661
13.

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.

Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FKB, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I.

Cell. 2016 Jan 14;164(1-2):325. doi: 10.1016/j.cell.2015.12.046. Epub 2016 Jan 14. No abstract available.

14.

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.

Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FK, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I.

Cell. 2015 Dec 17;163(7):1663-77. doi: 10.1016/j.cell.2015.11.013. Epub 2015 Nov 25. Erratum in: Cell. 2016 Jan 14;164(1-2):325.

15.

The multifaceted functions of C/EBPα in normal and malignant haematopoiesis.

Ohlsson E, Schuster MB, Hasemann M, Porse BT.

Leukemia. 2016 Apr;30(4):767-75. doi: 10.1038/leu.2015.324. Epub 2015 Nov 25. Review.

PMID:
26601784
16.

BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis.

Bagger FO, Sasivarevic D, Sohi SH, Laursen LG, Pundhir S, Sønderby CK, Winther O, Rapin N, Porse BT.

Nucleic Acids Res. 2016 Jan 4;44(D1):D917-24. doi: 10.1093/nar/gkv1101. Epub 2015 Oct 26.

17.

ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.

Knudsen KJ, Rehn M, Hasemann MS, Rapin N, Bagger FO, Ohlsson E, Willer A, Frank AK, Søndergaard E, Jendholm J, Thorén L, Lee J, Rak J, Theilgaard-Mönch K, Porse BT.

Genes Dev. 2015 Sep 15;29(18):1915-29. doi: 10.1101/gad.268409.115.

18.

Disease evolution and outcomes in familial AML with germline CEBPA mutations.

Tawana K, Wang J, Renneville A, Bödör C, Hills R, Loveday C, Savic A, Van Delft FW, Treleaven J, Georgiades P, Uglow E, Asou N, Uike N, Debeljak M, Jazbec J, Ancliff P, Gale R, Thomas X, Mialou V, Döhner K, Bullinger L, Mueller B, Pabst T, Stelljes M, Schlegelberger B, Wozniak E, Iqbal S, Okosun J, Araf S, Frank AK, Lauridsen FB, Porse B, Nerlov C, Owen C, Dokal I, Gribben J, Smith M, Preudhomme C, Chelala C, Cavenagh J, Fitzgibbon J.

Blood. 2015 Sep 3;126(10):1214-23. doi: 10.1182/blood-2015-05-647172. Epub 2015 Jul 10.

19.

Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.

Rasmussen KD, Jia G, Johansen JV, Pedersen MT, Rapin N, Bagger FO, Porse BT, Bernard OA, Christensen J, Helin K.

Genes Dev. 2015 May 1;29(9):910-22. doi: 10.1101/gad.260174.115. Epub 2015 Apr 17.

20.

Cellular origin of prognostic chromosomal aberrations in AML patients.

Mora-Jensen H, Jendholm J, Rapin N, Andersen MK, Roug AS, Bagger FO, Bullinger L, Winther O, Borregaard N, Porse BT, Theilgaard-Mönch K.

Leukemia. 2015 Aug;29(8):1785-9. doi: 10.1038/leu.2015.30. Epub 2015 Feb 11. No abstract available.

PMID:
25670329
21.

Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq.

Jakobsen JS, Bagger FO, Hasemann MS, Schuster MB, Frank AK, Waage J, Vitting-Seerup K, Porse BT.

BMC Genomics. 2015 Feb 5;16:46. doi: 10.1186/s12864-014-1195-4.

22.

UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome.

Bao J, Tang C, Yuan S, Porse BT, Yan W.

Development. 2015 Jan 15;142(2):352-62. doi: 10.1242/dev.115642. Epub 2014 Dec 11.

23.

TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.

Willer A, Jakobsen JS, Ohlsson E, Rapin N, Waage J, Billing M, Bullinger L, Karlsson S, Porse BT.

Leukemia. 2015 May;29(5):1018-31. doi: 10.1038/leu.2014.307. Epub 2014 Oct 28.

PMID:
25349154
24.

Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3.

Xu MJ, Feng D, Wu H, Wang H, Chan Y, Kolls J, Borregaard N, Porse B, Berger T, Mak TW, Cowland JB, Kong X, Gao B.

Hepatology. 2015 Feb;61(2):692-702. doi: 10.1002/hep.27447.

25.
26.

Integrative analysis of histone ChIP-seq and transcription data using Bayesian mixture models.

Klein HU, Schäfer M, Porse BT, Hasemann MS, Ickstadt K, Dugas M.

Bioinformatics. 2014 Apr 15;30(8):1154-1162. Epub 2014 Jan 7.

PMID:
24403540
27.

spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data.

Vitting-Seerup K, Porse BT, Sandelin A, Waage J.

BMC Bioinformatics. 2014 Mar 23;15:81. doi: 10.1186/1471-2105-15-81.

28.

Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation.

Rishi L, Hannon M, Salomè M, Hasemann M, Frank AK, Campos J, Timoney J, O'Connor C, Cahill MR, Porse B, Keeshan K.

Blood. 2014 Apr 10;123(15):2389-400. doi: 10.1182/blood-2013-07-511683. Epub 2014 Feb 10.

29.

shRNA screening identifies JMJD1C as being required for leukemia maintenance.

Sroczynska P, Cruickshank VA, Bukowski JP, Miyagi S, Bagger FO, Walfridsson J, Schuster MB, Porse B, Helin K.

Blood. 2014 Mar 20;123(12):1870-82. doi: 10.1182/blood-2013-08-522094. Epub 2014 Feb 5.

30.

C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors.

Hasemann MS, Lauridsen FK, Waage J, Jakobsen JS, Frank AK, Schuster MB, Rapin N, Bagger FO, Hoppe PS, Schroeder T, Porse BT.

PLoS Genet. 2014 Jan;10(1):e1004079. doi: 10.1371/journal.pgen.1004079. Epub 2014 Jan 9.

31.

C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner.

Norrie IC, Ohlsson E, Nielsen O, Hasemann MS, Porse BT.

PLoS One. 2014 Jan 3;9(1):e84728. doi: 10.1371/journal.pone.0084728. eCollection 2014.

32.

Initiation of MLL-rearranged AML is dependent on C/EBPα.

Ohlsson E, Hasemann MS, Willer A, Lauridsen FK, Rapin N, Jendholm J, Porse BT.

J Exp Med. 2014 Jan 13;211(1):5-13. doi: 10.1084/jem.20130932. Epub 2013 Dec 23.

33.

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.

Rapin N, Bagger FO, Jendholm J, Mora-Jensen H, Krogh A, Kohlmann A, Thiede C, Borregaard N, Bullinger L, Winther O, Theilgaard-Mönch K, Porse BT.

Blood. 2014 Feb 6;123(6):894-904. doi: 10.1182/blood-2013-02-485771. Epub 2013 Dec 20.

34.

The functional consequences of intron retention: alternative splicing coupled to NMD as a regulator of gene expression.

Ge Y, Porse BT.

Bioessays. 2014 Mar;36(3):236-43. doi: 10.1002/bies.201300156. Epub 2013 Dec 18. Review.

PMID:
24352796
35.

microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus.

Leucci E, Patella F, Waage J, Holmstrøm K, Lindow M, Porse B, Kauppinen S, Lund AH.

Sci Rep. 2013;3:2535. doi: 10.1038/srep02535.

36.

PRDM11 is dispensable for the maintenance and function of hematopoietic stem and progenitor cells.

Thoren LA, Fog CK, Jensen KT, Buza-Vidas N, Côme C, Lund AH, Porse BT.

Stem Cell Res. 2013 Nov;11(3):1129-36. doi: 10.1016/j.scr.2013.07.009. Epub 2013 Aug 9.

37.

Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors.

Schuster MB, Frank AK, Bagger FO, Rapin N, Vikesaa J, Porse BT.

Exp Hematol. 2013 Oct;41(10):882-893.e16. doi: 10.1016/j.exphem.2013.06.003. Epub 2013 Jul 2.

PMID:
23831605
38.

Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay.

Colak D, Ji SJ, Porse BT, Jaffrey SR.

Cell. 2013 Jun 6;153(6):1252-65. doi: 10.1016/j.cell.2013.04.056.

39.

Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries.

Jakobsen JS, Waage J, Rapin N, Bisgaard HC, Larsen FS, Porse BT.

Genome Res. 2013 Apr;23(4):592-603. doi: 10.1101/gr.146399.112. Epub 2013 Feb 12.

40.

HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.

Bagger FO, Rapin N, Theilgaard-Mönch K, Kaczkowski B, Thoren LA, Jendholm J, Winther O, Porse BT.

Nucleic Acids Res. 2013 Jan;41(Database issue):D1034-9. doi: 10.1093/nar/gks1021. Epub 2012 Nov 9.

41.

HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis.

Bagger FO, Rapin N, Theilgaard-Mönch K, Kaczkowski B, Jendholm J, Winther O, Porse B.

Blood. 2012 Jun 28;119(26):6394-5. doi: 10.1182/blood-2012-05-427310. No abstract available.

42.

Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency.

Hasemann MS, Schuster MB, Frank AK, Theilgaard-Mönch K, Pedersen TÅ, Nerlov C, Porse BT.

PLoS One. 2012;7(6):e38841. doi: 10.1371/journal.pone.0038841. Epub 2012 Jun 8.

43.

Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns.

Weischenfeldt J, Waage J, Tian G, Zhao J, Damgaard I, Jakobsen JS, Kristiansen K, Krogh A, Wang J, Porse BT.

Genome Biol. 2012 May 24;13(5):R35. doi: 10.1186/gb-2012-13-5-r35.

44.

BLUEPRINT to decode the epigenetic signature written in blood.

Adams D, Altucci L, Antonarakis SE, Ballesteros J, Beck S, Bird A, Bock C, Boehm B, Campo E, Caricasole A, Dahl F, Dermitzakis ET, Enver T, Esteller M, Estivill X, Ferguson-Smith A, Fitzgibbon J, Flicek P, Giehl C, Graf T, Grosveld F, Guigo R, Gut I, Helin K, Jarvius J, Küppers R, Lehrach H, Lengauer T, Lernmark Å, Leslie D, Loeffler M, Macintyre E, Mai A, Martens JH, Minucci S, Ouwehand WH, Pelicci PG, Pendeville H, Porse B, Rakyan V, Reik W, Schrappe M, Schübeler D, Seifert M, Siebert R, Simmons D, Soranzo N, Spicuglia S, Stratton M, Stunnenberg HG, Tanay A, Torrents D, Valencia A, Vellenga E, Vingron M, Walter J, Willcocks S.

Nat Biotechnol. 2012 Mar 7;30(3):224-6. doi: 10.1038/nbt.2153. No abstract available.

PMID:
22398613
45.

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2.

Zheng S, Gray EE, Chawla G, Porse BT, O'Dell TJ, Black DL.

Nat Neurosci. 2012 Jan 15;15(3):381-8, S1. doi: 10.1038/nn.3026.

46.

Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML.

Treppendahl MB, Qiu X, Søgaard A, Yang X, Nandrup-Bus C, Hother C, Andersen MK, Kjeldsen L, Möllgård L, Hellström-Lindberg E, Jendholm J, Porse BT, Jones PA, Liang G, Grønbæk K.

Blood. 2012 Jan 5;119(1):206-16. doi: 10.1182/blood-2011-06-362541. Epub 2011 Nov 4. Erratum in: Blood. 2013 Jun 20;121(25):5104. Möllgaard, Lars [corrected to Möllgård, Lars].

47.

Technical advance: immunophenotypical characterization of human neutrophil differentiation.

Mora-Jensen H, Jendholm J, Fossum A, Porse B, Borregaard N, Theilgaard-Mönch K.

J Leukoc Biol. 2011 Sep;90(3):629-34. doi: 10.1189/jlb.0311123. Epub 2011 Jun 7. Erratum in: J Leukoc Biol. 2012 Mar;91(3):517. J Leukoc Biol. 2012 Mar;91(3):517. Borregaad, Niels [corrected to Borregaard, Niels].

PMID:
21653237
48.

Gene expression profiling in MDS and AML: potential and future avenues.

Theilgaard-Mönch K, Boultwood J, Ferrari S, Giannopoulos K, Hernandez-Rivas JM, Kohlmann A, Morgan M, Porse B, Tagliafico E, Zwaan CM, Wainscoat J, Van den Heuvel-Eibrink MM, Mills K, Bullinger L.

Leukemia. 2011 Jun;25(6):909-20. doi: 10.1038/leu.2011.48. Epub 2011 Mar 29. Review.

PMID:
21445077
49.

[Basic stem cell biology and cancer].

Porse BT, Petersen OW, Helin K.

Ugeskr Laeger. 2010 Sep 20;172(38):2600-3. Danish.

PMID:
20920403
50.

UPF2 is a critical regulator of liver development, function and regeneration.

Thoren LA, Nørgaard GA, Weischenfeldt J, Waage J, Jakobsen JS, Damgaard I, Bergström FC, Blom AM, Borup R, Bisgaard HC, Porse BT.

PLoS One. 2010 Jul 19;5(7):e11650. doi: 10.1371/journal.pone.0011650.

51.

Lipocalin 2 is protective against E. coli pneumonia.

Wu H, Santoni-Rugiu E, Ralfkiaer E, Porse BT, Moser C, Høiby N, Borregaard N, Cowland JB.

Respir Res. 2010 Jul 15;11:96. doi: 10.1186/1465-9921-11-96.

52.

A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia.

Marstrand TT, Borup R, Willer A, Borregaard N, Sandelin A, Porse BT, Theilgaard-Mönch K.

Leukemia. 2010 Jul;24(7):1265-75. doi: 10.1038/leu.2010.95. Epub 2010 May 27.

PMID:
20508621
53.

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.

Pasini D, Malatesta M, Jung HR, Walfridsson J, Willer A, Olsson L, Skotte J, Wutz A, Porse B, Jensen ON, Helin K.

Nucleic Acids Res. 2010 Aug;38(15):4958-69. doi: 10.1093/nar/gkq244. Epub 2010 Apr 12.

54.

Leukemia - methods and protocols.

Porse B.

Eur J Haematol. 2010 Jan;84(1):94. Epub 2009 Sep 21. No abstract available.

PMID:
19769595
55.

C/EBPalpha in leukemogenesis: identity and origin of the leukemia-initiating cell.

Schuster MB, Porse BT.

Biofactors. 2009 May-Jun;35(3):227-31. doi: 10.1002/biof.36. Review.

PMID:
19322763
56.

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.

Weischenfeldt J, Damgaard I, Bryder D, Theilgaard-Mönch K, Thoren LA, Nielsen FC, Jacobsen SE, Nerlov C, Porse BT.

Genes Dev. 2008 May 15;22(10):1381-96. doi: 10.1101/gad.468808.

57.

Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.

Kirstetter P, Schuster MB, Bereshchenko O, Moore S, Dvinge H, Kurz E, Theilgaard-Mönch K, Månsson R, Pedersen TA, Pabst T, Schrock E, Porse BT, Jacobsen SE, Bertone P, Tenen DG, Nerlov C.

Cancer Cell. 2008 Apr;13(4):299-310. doi: 10.1016/j.ccr.2008.02.008.

58.

Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.

Hasemann MS, Damgaard I, Schuster MB, Theilgaard-Mönch K, Sørensen AB, Mrsic A, Krugers T, Ylstra B, Pedersen FS, Nerlov C, Porse BT.

Blood. 2008 Apr 15;111(8):4309-21. doi: 10.1182/blood-2007-06-097790. Epub 2008 Jan 22.

59.

Bone Marrow-Derived Macrophages (BMM): Isolation and Applications.

Weischenfeldt J, Porse B.

CSH Protoc. 2008 Dec 1;2008:pdb.prot5080. doi: 10.1101/pdb.prot5080.

PMID:
21356739
60.

Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice.

Christoffersen C, Jauhiainen M, Moser M, Porse B, Ehnholm C, Boesl M, Dahlbäck B, Nielsen LB.

J Biol Chem. 2008 Jan 25;283(4):1839-47. Epub 2007 Nov 15.

61.

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.

Bracken AP, Kleine-Kohlbrecher D, Dietrich N, Pasini D, Gargiulo G, Beekman C, Theilgaard-Mönch K, Minucci S, Porse BT, Marine JC, Hansen KH, Helin K.

Genes Dev. 2007 Mar 1;21(5):525-30.

62.

Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.

Pedersen TA, Bereshchenko O, Garcia-Silva S, Ermakova O, Kurz E, Mandrup S, Porse BT, Nerlov C.

EMBO J. 2007 Feb 21;26(4):1081-93. Epub 2007 Feb 8.

63.

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C.

Nat Immunol. 2006 Oct;7(10):1048-56. Epub 2006 Sep 3.

PMID:
16951689
64.

C/EBPalpha: a tumour suppressor in multiple tissues?

Schuster MB, Porse BT.

Biochim Biophys Acta. 2006 Aug;1766(1):88-103. Epub 2006 Mar 24. Review.

PMID:
16616425
65.

Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.

Theilgaard-Mönch K, Jacobsen LC, Nielsen MJ, Rasmussen T, Udby L, Gharib M, Arkwright PD, Gombart AF, Calafat J, Moestrup SK, Porse BT, Borregaard N.

Blood. 2006 Jul 1;108(1):353-61. Epub 2006 Mar 16.

66.

The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo.

Porse BT, Pedersen TA, Hasemann MS, Schuster MB, Kirstetter P, Luedde T, Damgaard I, Kurz E, Schjerling CK, Nerlov C.

Mol Cell Biol. 2006 Feb;26(3):1028-37.

67.

Systems biology of neutrophil differentiation and immune response.

Theilgaard-Mönch K, Porse BT, Borregaard N.

Curr Opin Immunol. 2006 Feb;18(1):54-60. Epub 2005 Dec 15. Review.

PMID:
16343884
68.

Messenger RNA surveillance: neutralizing natural nonsense.

Weischenfeldt J, Lykke-Andersen J, Porse B.

Curr Biol. 2005 Jul 26;15(14):R559-62. Review.

69.

Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.

Porse BT, Bryder D, Theilgaard-Mönch K, Hasemann MS, Anderson K, Damgaard I, Jacobsen SE, Nerlov C.

J Exp Med. 2005 Jul 4;202(1):85-96. Epub 2005 Jun 27.

70.

Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.

Theilgaard-Mönch K, Jacobsen LC, Rasmussen T, Niemann CU, Udby L, Borup R, Gharib M, Arkwright PD, Gombart AF, Calafat J, Porse BT, Borregaard N.

J Leukoc Biol. 2005 Aug;78(2):462-70. Epub 2005 Jun 7.

PMID:
15941779
71.

A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNA.

Andersen TE, Porse BT, Kirpekar F.

RNA. 2004 Jun;10(6):907-13.

72.
73.

[Transgenic mice as disease models].

Schuster MB, Porse BT.

Ugeskr Laeger. 2003 Feb 17;165(8):793-6. Danish.

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Cell. 2001 Oct 19;107(2):247-58.

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Puromycin-rRNA interaction sites at the peptidyl transferase center.

Rodriguez-Fonseca C, Phan H, Long KS, Porse BT, Kirillov SV, Amils R, Garrett RA.

RNA. 2000 May;6(5):744-54.

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Ribosomal mechanics, antibiotics, and GTP hydrolysis.

Porse BT, Garrett RA.

Cell. 1999 May 14;97(4):423-6. Review. No abstract available.

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The antibiotic micrococcin acts on protein L11 at the ribosomal GTPase centre.

Porse BT, Cundliffe E, Garrett RA.

J Mol Biol. 1999 Mar 19;287(1):33-45.

PMID:
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Assembly of proteins and 5 S rRNA to transcripts of the major structural domains of 23 S rRNA.

Ostergaard P, Phan H, Johansen LB, Egebjerg J, Ostergaard L, Porse BT, Garrett RA.

J Mol Biol. 1998 Nov 27;284(2):227-40.

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The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre.

Porse BT, Leviev I, Mankin AS, Garrett RA.

J Mol Biol. 1998 Feb 20;276(2):391-404.

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FEBS Lett. 1997 Apr 14;406(3):223-33. Review.

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Lázaro E, Rodriguez-Fonseca C, Porse B, Ureña D, Garrett RA, Ballesta JP.

J Mol Biol. 1996 Aug 16;261(2):231-8. Erratum in: J Mol Biol 1996 Dec 13;264(4):839.

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