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Did you mean three myeloid cell compartment cell by cell (561 results)?
The Myeloid Cell Compartment-Cell by Cell.
Bassler K, Schulte-Schrepping J, Warnat-Herresthal S, Aschenbrenner AC, Schultze JL. Bassler K, et al. Annu Rev Immunol. 2019 Apr 26;37:269-293. doi: 10.1146/annurev-immunol-042718-041728. Epub 2019 Jan 16. Annu Rev Immunol. 2019. PMID: 30649988 Review.
Myeloid cells are a major cellular compartment of the immune system comprising monocytes, dendritic cells, tissue macrophages, and granulocytes. ...Based on these exciting developments, we propose the next steps to a full understanding of the myeloi
Myeloid cells are a major cellular compartment of the immune system comprising monocytes, dendritic cells, tissu
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, De Domenico E, Wendisch D, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Dietrich O, Mei HE, Schulz AR, Conrad C, Kunkel D, Vafadarnejad E, Xu CJ, Horne A, Herbert M, Drews A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Raabe J, Kaiser KM, Vinh MT, Rieke G, Meisel C, Ulas T, Becker M, Geffers R, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Händler K, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Sawitzki B, Saliba AE, Sander LE; Deutsche COVID-19 OMICS Initiative (DeCOI). Schulte-Schrepping J, et al. Cell. 2020 Sep 17;182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001. Epub 2020 Aug 5. Cell. 2020. PMID: 32810438 Free PMC article.
The mechanism of protective immunity in mild forms and the pathogenesis of severe COVID-19 associated with increased neutrophil counts and dysregulated immune responses remain unclear. In a dual-center, two-cohort study, we combined single-cell RNA-sequencing and single- …
The mechanism of protective immunity in mild forms and the pathogenesis of severe COVID-19 associated with increased neutrophil counts and d …
A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling.
Qian J, Olbrecht S, Boeckx B, Vos H, Laoui D, Etlioglu E, Wauters E, Pomella V, Verbandt S, Busschaert P, Bassez A, Franken A, Bempt MV, Xiong J, Weynand B, van Herck Y, Antoranz A, Bosisio FM, Thienpont B, Floris G, Vergote I, Smeets A, Tejpar S, Lambrechts D. Qian J, et al. Cell Res. 2020 Sep;30(9):745-762. doi: 10.1038/s41422-020-0355-0. Epub 2020 Jun 19. Cell Res. 2020. PMID: 32561858 Free PMC article.
The stromal compartment of the tumor microenvironment consists of a heterogeneous set of tissue-resident and tumor-infiltrating cells, which are profoundly moulded by cancer cells. An outstanding question is to what extent this heterogeneity is similar betwee …
The stromal compartment of the tumor microenvironment consists of a heterogeneous set of tissue-resident and tumor-infiltrating ce
Mechanisms of myeloid cell entry to the healthy and diseased central nervous system.
Amann L, Masuda T, Prinz M. Amann L, et al. Nat Immunol. 2023 Mar;24(3):393-407. doi: 10.1038/s41590-022-01415-8. Epub 2023 Feb 9. Nat Immunol. 2023. PMID: 36759712 Review.
The complementary usage of multimodal high-throughput and high-dimensional single-cell technologies along with recent advances in cell-fate mapping has revealed remarkable myeloid cell heterogeneity in the CNS. ...These insights offer better understand …
The complementary usage of multimodal high-throughput and high-dimensional single-cell technologies along with recent advances in …
Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.
Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. Broz ML, et al. Cancer Cell. 2014 Nov 10;26(5):638-52. doi: 10.1016/j.ccell.2014.09.007. Epub 2014 Oct 16. Cancer Cell. 2014. PMID: 25446897 Free PMC article.
It is well understood that antigen-presenting cells (APCs) within tumors typically do not maintain cytotoxic T cell (CTL) function, despite engaging them. ...These are uniquely dependent on IRF8, Zbtb46, and Batf3 transcription factors and are generated by GM-CSF an …
It is well understood that antigen-presenting cells (APCs) within tumors typically do not maintain cytotoxic T cell (CTL) func …
Myeloid cell-targeted therapies for solid tumours.
Goswami S, Anandhan S, Raychaudhuri D, Sharma P. Goswami S, et al. Nat Rev Immunol. 2023 Feb;23(2):106-120. doi: 10.1038/s41577-022-00737-w. Epub 2022 Jun 13. Nat Rev Immunol. 2023. PMID: 35697799 Review.
The myeloid cell compartment comprises many different cell types, including monocytes, macrophages, dendritic cells and granulocytes, that are highly plastic and can differentiate into diverse phenotypes depending on cues received from their mic …
The myeloid cell compartment comprises many different cell types, including monocytes, macrophages, dendritic …
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation.
Jordão MJC, Sankowski R, Brendecke SM, Sagar, Locatelli G, Tai YH, Tay TL, Schramm E, Armbruster S, Hagemeyer N, Groß O, Mai D, Çiçek Ö, Falk T, Kerschensteiner M, Grün D, Prinz M. Jordão MJC, et al. Science. 2019 Jan 25;363(6425):eaat7554. doi: 10.1126/science.aat7554. Science. 2019. PMID: 30679343
However, this complexity is increased in inflammatory settings by the recruitment of circulating myeloid cells. It is unclear which disease-specific myeloid subsets exist and what their transcriptional profiles and dynamics during CNS pathology are. ...Last, …
However, this complexity is increased in inflammatory settings by the recruitment of circulating myeloid cells. It is unclear …
Involvement of the myeloid cell compartment in fibrogenesis and systemic sclerosis.
Kania G, Rudnik M, Distler O. Kania G, et al. Nat Rev Rheumatol. 2019 May;15(5):288-302. doi: 10.1038/s41584-019-0212-z. Nat Rev Rheumatol. 2019. PMID: 30953037 Review.
In this Review, we summarize current knowledge about the function of myeloid cells in fibrogenesis that occurs in patients with SSc. Targeted therapies currently in clinical studies for SSc might affect myeloid cell-related pathways. Therefore, myel
In this Review, we summarize current knowledge about the function of myeloid cells in fibrogenesis that occurs in patients wit …
A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment.
Rose S, Misharin A, Perlman H. Rose S, et al. Cytometry A. 2012 Apr;81(4):343-50. doi: 10.1002/cyto.a.22012. Epub 2011 Dec 29. Cytometry A. 2012. PMID: 22213571 Free PMC article.
Currently, there is no standardized panel for immunophenotyping myeloid cells in mouse spleen using flow cytometry. Markers such as CD11b, CD11c, F4/80, Gr-1, Ly6C, and Ly6G have long been used to identify various splenic cell myeloid populations. ...T …
Currently, there is no standardized panel for immunophenotyping myeloid cells in mouse spleen using flow cytometry. Markers su …
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization.
Pombo Antunes AR, Scheyltjens I, Lodi F, Messiaen J, Antoranz A, Duerinck J, Kancheva D, Martens L, De Vlaminck K, Van Hove H, Kjølner Hansen SS, Bosisio FM, Van der Borght K, De Vleeschouwer S, Sciot R, Bouwens L, Verfaillie M, Vandamme N, Vandenbroucke RE, De Wever O, Saeys Y, Guilliams M, Gysemans C, Neyns B, De Smet F, Lambrechts D, Van Ginderachter JA, Movahedi K. Pombo Antunes AR, et al. Nat Neurosci. 2021 Apr;24(4):595-610. doi: 10.1038/s41593-020-00789-y. Epub 2021 Mar 29. Nat Neurosci. 2021. PMID: 33782623
Glioblastomas are aggressive primary brain cancers that recur as therapy-resistant tumors. Myeloid cells control glioblastoma malignancy, but their dynamics during disease progression remain poorly understood. ...This revealed a large and diverse myeloid c
Glioblastomas are aggressive primary brain cancers that recur as therapy-resistant tumors. Myeloid cells control glioblastoma …
7,347 results