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Oral Oncol. 2019 Jan;88:186-189. doi: 10.1016/j.oraloncology.2018.11.019. Epub 2018 Nov 22.

Lingual ectopic papillary thyroid carcinoma: Two case reports and review of the literature.

Author information

1
Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: huangnaisi@fudan.edu.cn.
2
Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
3
Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: jiqinghai@shca.org.cn.

Abstract

Ectopic thyroid occurs when it is not located on the normal thyroid compartment. While 90% of the ectopic thyroids were located at the base of the tongue, only 1% were lingual thyroid carcinoma (LTC). Only 56 LTC cases have been reported so far. Here we reported two cases of LTC. Patient 1 was a 47-year-old female with LTC and co-current sub-hyoid ectopic thyroid. She experienced major hematemesis and dyspnea requiring emergent tracheotomy. Patient 2 was a 61-year old female who was presented with LTC with multiple lymph node metastasis and bilateral lung metastasis. Both of the patients' lingual masses were removed via trans-submaxillary excisions. Pathology revealed ectopic papillary thyroid carcinoma. Then they were treated with radio-active iodine (RAI). These patients had full recovery and there were no complications. A review of literature was also presented.

KEYWORDS:

Ectopic thyroid carcinoma; Head and neck cancer; Lingual thyroid carcinoma; Papillary thyroid carcinoma; Thyroid cancer

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