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J Infect Public Health. 2017 Mar - Apr;10(2):224-227. doi: 10.1016/j.jiph.2016.05.001. Epub 2016 Jun 30.

Immune Reconstitution Syndrome secondary to Rhodococcus equi infection in a patient with HIV and Burkitt's lymphoma.

Author information

1
Department of Medicine, College of Medicine, Jazan University, Jazan, Saudi Arabia; Section of Medical Microbiology, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
2
Section of General Internal Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
3
Section of Medical Microbiology, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
4
Section of Medical Microbiology, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: keynan@yahoo.com.

Abstract

Immune Reconstitution Syndrome (IRIS) has been associated with a variety of infections in patients with human immunodeficiency virus (HIV). However, we are reporting the first case of IRIS secondary to Rhodococcus equi (R. equi) in a patient with HIV. We report the case of a 48-year-old male found to have HIV infection in the setting of Burkitt's lymphoma. While on anti-retroviral therapy and chemotherapy, he had developed IRIS secondary to R. equi that manifested as a cavitating pneumonia. This report outlines the successful management of the R. equi infection with the use of a combination of antibiotics, radiographic follow up and suppressive antibiotic while on chemotherapy.

KEYWORDS:

Burkitt's lymphoma; Cavitating pneumonia; Human immunodeficiency virus; Rhodococcus equi

PMID:
27373968
DOI:
10.1016/j.jiph.2016.05.001
[Indexed for MEDLINE]
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