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Scand Cardiovasc J. 2005 Apr;39(1-2):96-101.

Predictor of neurologic dysfunction after elective thoracic aorta repair using selective cerebral perfusion.

Author information

1
The Department of Surgery 2, Miyazaki Medical College, University of Miyazaki, Miyazaki, Japan. shiori@med.miyazaki-u.ac.jp

Abstract

OBJECTIVES:

This study was undertaken to determine the factors that influence postoperative neurological dysfunction after selective cerebral perfusion (SCP).

DESIGN:

From 1995 to August 2004, 60 patients were evaluated for the presence of cerebro-vascular disease (CVD), and then underwent thoracic aortic operations using SCP. Perioperative factors were evaluated by multivariate analyses.

RESULTS:

Hospital mortality rate was zero. Sixteen patients (26.7%) proved to have CVD. Permanent neurological dysfunction (PND) appeared in three patients (5.0%) and transient neurological dysfunction (TND) in two (3.3%). Univariate analysis revealed superficial temporal artery (STA) pressure during SCP (p = 0.0410) to be a significant risk factor for PND. Variables that achieved values of p < 0.2 (aortic cross-clamp time, presence of CVD, old cerebral infarction, presence of clots or atheroma) were examined with multivariate analysis and the presence of CVD (p = 0.038) and STA pressure during SCP (p = 0.032) were independent risk factors for PND. Multivariate analysis for TND did not show any risk factor.

CONCLUSIONS:

The presence of CVD was indicated as an independent risk factor for PND after thoracic aortic operations using SCP.

PMID:
16097422
[Indexed for MEDLINE]

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