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Items: 1 to 20 of 152


A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons.

Chen DM, Ziolkowski L, Benz A, Qian M, Zorumski CF, Covey DF, Mennerick S.

Front Neurosci. 2018 Dec 6;12:923. doi: 10.3389/fnins.2018.00923. eCollection 2018.


Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization.

Chisari M, Wilding TJ, Brunwasser S, Krishnan K, Qian M, Benz A, Huettner JE, Zorumski CF, Covey DF, Mennerick S.

Neuropharmacology. 2019 Jan;144:91-103. doi: 10.1016/j.neuropharm.2018.10.015. Epub 2018 Oct 15.


Chemogenetic Isolation Reveals Synaptic Contribution of δ GABAA Receptors in Mouse Dentate Granule Neurons.

Sun MY, Shu HJ, Benz A, Bracamontes J, Akk G, Zorumski CF, Steinbach JH, Mennerick SJ.

J Neurosci. 2018 Sep 19;38(38):8128-8145. doi: 10.1523/JNEUROSCI.0799-18.2018. Epub 2018 Aug 3.


Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam.

Cao LQ, Montana MC, Germann AL, Shin DJ, Chakrabarti S, Mennerick S, Yuede CM, Wozniak DF, Evers AS, Akk G.

Sci Rep. 2018 Jul 9;8(1):10341. doi: 10.1038/s41598-018-28754-7.


Ambient but not local lactate underlies neuronal tolerance to prolonged glucose deprivation.

Sobieski C, Warikoo N, Shu HJ, Mennerick S.

PLoS One. 2018 Apr 4;13(4):e0195520. doi: 10.1371/journal.pone.0195520. eCollection 2018.


Positive Allosteric Modulation as a Potential Therapeutic Strategy in Anti-NMDA Receptor Encephalitis.

Warikoo N, Brunwasser SJ, Benz A, Shu HJ, Paul SM, Lewis M, Doherty J, Quirk M, Piccio L, Zorumski CF, Day GS, Mennerick S.

J Neurosci. 2018 Mar 28;38(13):3218-3229. doi: 10.1523/JNEUROSCI.3377-17.2018. Epub 2018 Feb 23.


Contributions of space-clamp errors to apparent time-dependent loss of Mg2+ block induced by NMDA.

Sun MY, Chisari M, Eisenman LN, Zorumski CF, Mennerick SJ.

J Neurophysiol. 2017 Jul 1;118(1):532-543. doi: 10.1152/jn.00106.2017. Epub 2017 Mar 29.


24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation.

Sun MY, Taylor A, Zorumski CF, Mennerick S.

PLoS One. 2017 Mar 27;12(3):e0174416. doi: 10.1371/journal.pone.0174416. eCollection 2017.


Differential Presynaptic ATP Supply for Basal and High-Demand Transmission.

Sobieski C, Fitzpatrick MJ, Mennerick SJ.

J Neurosci. 2017 Feb 15;37(7):1888-1899. doi: 10.1523/JNEUROSCI.2712-16.2017. Epub 2017 Jan 16.


A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons.

Emnett C, Li H, Jiang X, Benz A, Boggiano J, Conyers S, Wozniak DF, Zorumski CF, Reichert DE, Mennerick S.

Sci Rep. 2016 Dec 16;6:38808. doi: 10.1038/srep38808.


Ketamine: NMDA Receptors and Beyond.

Zorumski CF, Izumi Y, Mennerick S.

J Neurosci. 2016 Nov 2;36(44):11158-11164.


Correcting mitochondrial fusion by manipulating mitofusin conformations.

Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW II.

Nature. 2016 Dec 1;540(7631):74-79. doi: 10.1038/nature20156. Epub 2016 Oct 24.


A complement-microglial axis drives synapse loss during virus-induced memory impairment.

Vasek MJ, Garber C, Dorsey D, Durrant DM, Bollman B, Soung A, Yu J, Perez-Torres C, Frouin A, Wilton DK, Funk K, DeMasters BK, Jiang X, Bowen JR, Mennerick S, Robinson JK, Garbow JR, Tyler KL, Suthar MS, Schmidt RE, Stevens B, Klein RS.

Nature. 2016 Jun 23;534(7608):538-43. doi: 10.1038/nature18283.


A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibition.

Jiang X, Shu HJ, Krishnan K, Qian M, Taylor AA, Covey DF, Zorumski CF, Mennerick S.

Neuropharmacology. 2016 Sep;108:193-206. doi: 10.1016/j.neuropharm.2016.04.031. Epub 2016 Apr 22.


Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABA(A) Receptors.

Chakrabarti S, Qian M, Krishnan K, Covey DF, Mennerick S, Akk G.

Mol Pharmacol. 2016 Apr;89(4):399-406. doi: 10.1124/mol.115.102202. Epub 2016 Jan 14.


Endogenous 24S-hydroxycholesterol modulates NMDAR-mediated function in hippocampal slices.

Sun MY, Izumi Y, Benz A, Zorumski CF, Mennerick S.

J Neurophysiol. 2016 Mar;115(3):1263-72. doi: 10.1152/jn.00890.2015. Epub 2015 Dec 23.


Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as Therapy.

Zorumski CF, Nagele P, Mennerick S, Conway CR.

Front Psychiatry. 2015 Dec 9;6:172. doi: 10.3389/fpsyt.2015.00172. eCollection 2015. Review.


Loss of Local Astrocyte Support Disrupts Action Potential Propagation and Glutamate Release Synchrony from Unmyelinated Hippocampal Axon Terminals In Vitro.

Sobieski C, Jiang X, Crawford DC, Mennerick S.

J Neurosci. 2015 Aug 5;35(31):11105-17. doi: 10.1523/JNEUROSCI.1289-15.2015.


Quantification of bursting and synchrony in cultured hippocampal neurons.

Eisenman LN, Emnett CM, Mohan J, Zorumski CF, Mennerick S.

J Neurophysiol. 2015 Aug;114(2):1059-71. doi: 10.1152/jn.00079.2015. Epub 2015 Jun 3.


24(S)-Hydroxycholesterol as a Modulator of Neuronal Signaling and Survival.

Sun MY, Linsenbardt AJ, Emnett CM, Eisenman LN, Izumi Y, Zorumski CF, Mennerick S.

Neuroscientist. 2016 Apr;22(2):132-44. doi: 10.1177/1073858414568122. Epub 2015 Jan 27. Review.

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