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Items: 1 to 20 of 106


Malformation of junctional microdomains in cataract lens membranes from a type II diabetes patient.

Mangenot S, Buzhynskyy N, Girmens JF, Scheuring S.

Pflugers Arch. 2009 Apr;457(6):1265-74. doi: 10.1007/s00424-008-0604-4. Epub 2008 Nov 26.


High-speed atomic force microscopy: cooperative adhesion and dynamic equilibrium of junctional microdomain membrane proteins.

Colom A, Casuso I, Boudier T, Scheuring S.

J Mol Biol. 2012 Oct 19;423(2):249-56. doi: 10.1016/j.jmb.2012.07.004. Epub 2012 Jul 14.


Structural models of the supramolecular organization of AQP0 and connexons in junctional microdomains.

Scheuring S, Buzhynskyy N, Jaroslawski S, Gonçalves RP, Hite RK, Walz T.

J Struct Biol. 2007 Dec;160(3):385-94. Epub 2007 Jul 28.


The supramolecular architecture of junctional microdomains in native lens membranes.

Buzhynskyy N, Hite RK, Walz T, Scheuring S.

EMBO Rep. 2007 Jan;8(1):51-5. Epub 2006 Nov 24.


Human cataract lens membrane at subnanometer resolution.

Buzhynskyy N, Girmens JF, Faigle W, Scheuring S.

J Mol Biol. 2007 Nov 16;374(1):162-9. Epub 2007 Sep 14.


Regional changes of AQP0-dependent square array junction and gap junction associated with cortical cataract formation in the Emory mutant mouse.

Biswas SK, Brako L, Gu S, Jiang JX, Lo WK.

Exp Eye Res. 2014 Oct;127:132-42. doi: 10.1016/j.exer.2014.07.020. Epub 2014 Jul 31.


Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50.

Liu J, Xu J, Gu S, Nicholson BJ, Jiang JX.

J Cell Sci. 2011 Jan 15;124(Pt 2):198-206. doi: 10.1242/jcs.072652. Epub 2010 Dec 20.


Interaction of major intrinsic protein (aquaporin-0) with fiber connexins in lens development.

Yu XS, Jiang JX.

J Cell Sci. 2004 Feb 29;117(Pt 6):871-80. Epub 2004 Feb 3.


Aquaporin-0 targets interlocking domains to control the integrity and transparency of the eye lens.

Lo WK, Biswas SK, Brako L, Shiels A, Gu S, Jiang JX.

Invest Ophthalmol Vis Sci. 2014 Mar 3;55(3):1202-12. doi: 10.1167/iovs.13-13379.


Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative manner.

Banks EA, Toloue MM, Shi Q, Zhou ZJ, Liu J, Nicholson BJ, Jiang JX.

J Cell Sci. 2009 Feb 1;122(Pt 3):378-88. doi: 10.1242/jcs.034124. Epub 2009 Jan 6.


Dynamic control of slow water transport by aquaporin 0: implications for hydration and junction stability in the eye lens.

Jensen MØ, Dror RO, Xu H, Borhani DW, Arkin IT, Eastwood MP, Shaw DE.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14430-5. doi: 10.1073/pnas.0802401105. Epub 2008 Sep 11.


Dominant cataracts result from incongruous mixing of wild-type lens connexins.

Martinez-Wittinghan FJ, Sellitto C, Li L, Gong X, Brink PR, Mathias RT, White TW.

J Cell Biol. 2003 Jun 9;161(5):969-78. Epub 2003 Jun 2.


Sorting of lens aquaporins and connexins into raft and nonraft bilayers: role of protein homo-oligomerization.

Tong J, Briggs MM, Mlaver D, Vidal A, McIntosh TJ.

Biophys J. 2009 Nov 4;97(9):2493-502. doi: 10.1016/j.bpj.2009.08.026.


Functional characterization of an AQP0 missense mutation, R33C, that causes dominant congenital lens cataract, reveals impaired cell-to-cell adhesion.

Kumari SS, Gandhi J, Mustehsan MH, Eren S, Varadaraj K.

Exp Eye Res. 2013 Nov;116:371-85. doi: 10.1016/j.exer.2013.09.019. Epub 2013 Oct 9.


Aquaporin 0 Modulates Lens Gap Junctions in the Presence of Lens-Specific Beaded Filament Proteins.

Kumari S, Gao J, Mathias RT, Sun X, Eswaramoorthy A, Browne N, Zhang N, Varadaraj K.

Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6006-6019. doi: 10.1167/iovs.17-22153.


Structural function of MIP/aquaporin 0 in the eye lens; genetic defects lead to congenital inherited cataracts.

Chepelinsky AB.

Handb Exp Pharmacol. 2009;(190):265-97. doi: 10.1007/978-3-540-79885-9_14. Review.


Co-expression of lens fiber connexins modifies hemi-gap-junctional channel behavior.

Ebihara L, Xu X, Oberti C, Beyer EC, Berthoud VM.

Biophys J. 1999 Jan;76(1 Pt 1):198-206.


Unique and analogous functions of aquaporin 0 for fiber cell architecture and ocular lens transparency.

Kumari SS, Eswaramoorthy S, Mathias RT, Varadaraj K.

Biochim Biophys Acta. 2011 Sep;1812(9):1089-97. doi: 10.1016/j.bbadis.2011.04.001. Epub 2011 Apr 12.

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