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Year Number of Results
1990 1
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1992 7
1993 19
1994 17
1995 18
1996 21
1997 22
1998 27
1999 8
2000 8
2001 14
2002 10
2003 5
2004 1
2005 4
2006 9
2007 6
2008 2
2009 4
2010 2
2011 2
2012 2
2013 3
2014 2
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2024 0

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228 results

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Page 1
Imiglucerase.
[No authors listed] [No authors listed] 2020 Apr 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2020 Apr 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000750 Free Books & Documents. Review.
An international panel of clinicians from 9 centers that treat Gaucher's disease reported that, breastfeeding complications were less frequent in mothers who were treated with imiglucerase or alglucerase (the placenta-derived form of the enzyme) postpartum than in untreate …
An international panel of clinicians from 9 centers that treat Gaucher's disease reported that, breastfeeding complications were less freque …
Alglucerase.
[No authors listed] [No authors listed] 2021 Apr 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Apr 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000749 Free Books & Documents. Review.
Alglucerase is the placenta-derived form of the enzyme, beta-glucocerebrosidase which is a normal component of human milk. Studies with alglucerase and synthetic forms of the enzyme have found very low levels of the enzyme in breastmilk. ...
Alglucerase is the placenta-derived form of the enzyme, beta-glucocerebrosidase which is a normal component of human milk. Studies wi …
Taliglucerase Alfa.
[No authors listed] [No authors listed] 2021 May 17. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 May 17. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000979 Free Books & Documents. Review.
Because it is a large protein molecule with a molecular weight of about 61,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract.[1,2] A limited amount of data support the safety of brea …
Because it is a large protein molecule with a molecular weight of about 61,000, the amount in milk is likely to be very low and absorption i …
Velaglucerase Alfa.
[No authors listed] [No authors listed] 2021 May 17. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 May 17. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000768 Free Books & Documents. Review.
Absorption by the infant is unlikely because it is probably destroyed in the infant's gastrointestinal tract.[1,2] A limited amount of data support the safety of breastfeeding with alglucerase (the placenta-derived form of the enzyme) and imiglucerase (another biosynthetic …
Absorption by the infant is unlikely because it is probably destroyed in the infant's gastrointestinal tract.[1,2] A limited amount of data …
Gaucher disease.
Beutler E. Beutler E. Curr Opin Hematol. 1997 Jan;4(1):19-23. doi: 10.1097/00062752-199704010-00004. Curr Opin Hematol. 1997. PMID: 9050375 Review.
Pulmonary involvement, usually regarded as a very rare manifestation, has received more attention recently, and minor abnormalities have been documented in many patients. Replacement of the deficient enzyme with alglucerase or the recombinant from of glucocerebrosidase imi …
Pulmonary involvement, usually regarded as a very rare manifestation, has received more attention recently, and minor abnormalities have bee …
Alglucerase. A pharmacoeconomic appraisal of its use in the treatment of Gaucher's disease.
Whittington R, Goa KL. Whittington R, et al. Pharmacoeconomics. 1995 Jan;7(1):63-90. doi: 10.2165/00019053-199507010-00007. Pharmacoeconomics. 1995. PMID: 10155294 Review.
Alglucerase is a modified form of human placental glucocerebrosidase used as enzyme replacement therapy for patients with Gaucher's disease, in whom functional glucocerebrosidase is deficient. Alglucerase has provided a breakthrough in treatment for patients with th …
Alglucerase is a modified form of human placental glucocerebrosidase used as enzyme replacement therapy for patients with Gaucher's d …
Alglucerase. A review of its therapeutic use in Gaucher's disease.
Whittington R, Goa KL. Whittington R, et al. Drugs. 1992 Jul;44(1):72-93. doi: 10.2165/00003495-199244010-00007. Drugs. 1992. PMID: 1379912 Review.
Alglucerase is a mannose-terminated form of human placental glucocerebrosidase, developed to treat patients with Gaucher's disease. ...Spleen and liver size are reduced, and skeletal parameters improve. Children gain height and most patients receiving alglucerase th …
Alglucerase is a mannose-terminated form of human placental glucocerebrosidase, developed to treat patients with Gaucher's disease. . …
Enzyme replacement therapy for Gaucher's disease.
Beutler E. Beutler E. Baillieres Clin Haematol. 1997 Dec;10(4):751-63. doi: 10.1016/s0950-3536(97)80038-8. Baillieres Clin Haematol. 1997. PMID: 9497862 Review.
Modified placental human glucocerebrosidase (alglucerase) and recombinant glucocerebrosidase (imiglucerase) are effective means of treating Type 1 Gaucher's disease. ...All available data thus support the administration of no more than 15 to 30 U of alglucerase or i …
Modified placental human glucocerebrosidase (alglucerase) and recombinant glucocerebrosidase (imiglucerase) are effective means of tr …
The female Gaucher patient: the impact of enzyme replacement therapy around key reproductive events (menstruation, pregnancy and menopause).
Zimran A, Morris E, Mengel E, Kaplan P, Belmatoug N, Hughes DA, Malinova V, Heitner R, Sobreira E, Mrsić M, Granovsky-Grisaru S, Amato D, vom Dahl S. Zimran A, et al. Blood Cells Mol Dis. 2009 Nov-Dec;43(3):264-88. doi: 10.1016/j.bcmd.2009.04.003. Epub 2009 Jun 6. Blood Cells Mol Dis. 2009. PMID: 19502088 Review.
Menorrhagia: Appears to be more common in GD than in the non-Gaucher population and may be ameliorated by alglucerase and/or imiglucerase treatment (menorrhagia in 67/133 (50.4%) untreated females compared with 37/128 (28.9%) treated; Mann-Whitney U test: p=0.001). ...Ther …
Menorrhagia: Appears to be more common in GD than in the non-Gaucher population and may be ameliorated by alglucerase and/or imigluce …
Alglucerase (Ceredase).
Wiltink EH, Hollak CE. Wiltink EH, et al. Pharm World Sci. 1996 Jan;18(1):16-9. doi: 10.1007/BF00449684. Pharm World Sci. 1996. PMID: 8861826 Review. No abstract available.
228 results