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Page 1
Identification and quantification of 4-methylethcathinone (4-MEC) and 3,4-methylenedioxypyrovalerone (MDPV) in hair by LC-MS/MS after chronic administration.
Alvarez JC, Etting I, Abe E, Villa A, Fabresse N. Alvarez JC, et al. Forensic Sci Int. 2017 Jan;270:39-45. doi: 10.1016/j.forsciint.2016.11.028. Epub 2016 Nov 24. Forensic Sci Int. 2017. PMID: 27914279
4-Methylethcathinone (4-MEC) and 3,4-methylenedioxypyrovalerone (MDPV) are synthetic cathinones. ...
4-Methylethcathinone (4-MEC) and 3,4-methylenedioxypyrovalerone (MDPV) are synthetic cathinones. ...
Drug-facilitated sexual assault (DFSA) involving 4-methylethcathinone (4-MEC), 3,4-Methylenedioxypyrovalerone (MDPV), and doxylamine highlighted by hair analysis.
Larabi IA, Martin M, Etting I, Penot P, Fabresse N, Alvarez JC. Larabi IA, et al. Drug Test Anal. 2018 Mar 10. doi: 10.1002/dta.2377. Online ahead of print. Drug Test Anal. 2018. PMID: 29524346
After alkaline liquid extraction and chromatographic separation on 1.9 mum Hypersil GOLD PFP column, compounds were detected by a TSQ Vantage mass spectrometer with electrospray ionization in positive mode with multiple reaction monitoring (MRM) acquisition. 4-methyleth …
After alkaline liquid extraction and chromatographic separation on 1.9 mum Hypersil GOLD PFP column, compounds were detected by a TSQ Vantag …
An Internet Study of User's Experiences of the Synthetic Cathinone 4-Methylethcathinone (4-MEC).
Van Hout MC. Van Hout MC. J Psychoactive Drugs. 2014 Oct-Dec;46(4):273-86. doi: 10.1080/02791072.2014.934979. J Psychoactive Drugs. 2014. PMID: 25188697
Abstract A synthetic cathinone called 4-methylethcathinone (4-MEC) emerged online in 2010, and was cyber-marketed to be a replacement for mephedrone. ...
Abstract A synthetic cathinone called 4-methylethcathinone (4-MEC) emerged online in 2010, and was cyber-marketed to be a repl …
The Effects of 4-Methylethcathinone on Conditioned Place Preference, Locomotor Sensitization, and Anxiety-Like Behavior: A Comparison with Methamphetamine.
Xu P, Qiu Y, Zhang Y, Βai Y, Xu P, Liu Y, Kim JH, Shen HW. Xu P, et al. Int J Neuropsychopharmacol. 2016 Apr 20;19(4):pyv120. doi: 10.1093/ijnp/pyv120. Print 2016 Apr. Int J Neuropsychopharmacol. 2016. PMID: 26612552 Free PMC article.
At 30 mg/kg, however, acute 4-methylethcathinone increased locomotor activity compared with saline, while chronic 4-methylethcathinone induced a delayed and attenuated sensitization compared with methamphetamine. ...Additionally, chronic 4-me …
At 30 mg/kg, however, acute 4-methylethcathinone increased locomotor activity compared with saline, while chronic 4- …
Methylenedioxymethamphetamine-like discriminative stimulus effects of seven cathinones in rats.
Gatch MB, Dolan SB, Forster MJ. Gatch MB, et al. Behav Pharmacol. 2020 Jun;31(4):378-384. doi: 10.1097/FBP.0000000000000540. Behav Pharmacol. 2020. PMID: 31895060
In order to determine their likelihood of interchangeability with entactogenic club drugs, the discriminative stimulus effects of methcathinone, 4-fluoromethcathinone, 4-methylmethcathinone, 4-methylethcathinone, 3-fluoromethcathinone, pentedrone, and ethylone were …
In order to determine their likelihood of interchangeability with entactogenic club drugs, the discriminative stimulus effects of methcathin …
Fatal 4-MEC Intoxication: Case Report and Review of Literature.
Braham MY, Franchi A, Cartiser N, Bévalot F, Bottinelli C, Fabrizi H, Fanton L. Braham MY, et al. Am J Forensic Med Pathol. 2021 Mar 1;42(1):57-61. doi: 10.1097/PAF.0000000000000599. Am J Forensic Med Pathol. 2021. PMID: 32773434 Review.
Synthetic cathinones are one of the major pharmacological families of new psychoactive substances and 4-methylethcathinone (4-MEC) has emerged in recent years as a recreational psychostimulant. ...Although no anatomic cause of death was observed at autopsy, toxicolo …
Synthetic cathinones are one of the major pharmacological families of new psychoactive substances and 4-methylethcathinone (4- …
Reporting Two Fatalities Associated with the Use of 4-Methylethcathinone (4-MEC) and a Review of the Literature.
Smith PR, Cole R, Hamilton S, West K, Morley SR, Maskell PD. Smith PR, et al. J Anal Toxicol. 2016 Sep;40(7):553-60. doi: 10.1093/jat/bkw061. Epub 2016 Jul 11. J Anal Toxicol. 2016. PMID: 27405367
We report two fatalities that are related to the cathinone 4-methylethcathinone (4-MEC) and review the current knowledge of 4-MEC. ...
We report two fatalities that are related to the cathinone 4-methylethcathinone (4-MEC) and review the current knowledge of 4- …
The involvement of calcium in the toxic effect of 4-methylethcathinone on SH-SY5Y cells.
Zhang W, Cao F, Li M, Xu Z, Sun J, Huang Z, Shi P. Zhang W, et al. J Appl Toxicol. 2024 Apr;44(4):553-563. doi: 10.1002/jat.4560. Epub 2023 Nov 11. J Appl Toxicol. 2024. PMID: 37950502
In the present study, we aimed to evaluate the occurrence of calcium dysregulation and its contribution to cytotoxicity in human neurotypic SH-SY5Y cells challenged with a recently developed psychoactive substance 4-methylethcathinone (4-MEC). An increase in the int …
In the present study, we aimed to evaluate the occurrence of calcium dysregulation and its contribution to cytotoxicity in human neurotypic …
Electron activated dissociation - a complementary fragmentation technique to collision-induced dissociation for metabolite identification of synthetic cathinone positional isomers.
Che P, Davidson JT, Kool J, Kohler I. Che P, et al. Anal Chim Acta. 2023 Dec 1;1283:341962. doi: 10.1016/j.aca.2023.341962. Epub 2023 Oct 26. Anal Chim Acta. 2023. PMID: 37977786 Free article.
The in vitro metabolism of 2-methylethcathinone (2-MEC), 3-methylethcathinone (3-MEC) and 4-methylethcathinone (4-MEC) was investigated with both CID and EAD methods using LC-HRMS(2). ...
The in vitro metabolism of 2-methylethcathinone (2-MEC), 3-methylethcathinone (3-MEC) and 4-methylethcathinone (4-MEC) was inv …
Neonatal withdrawal syndrome after chronic maternal consumption of 4-methylethcathinone.
Pichini S, Rotolo MC, García J, Girona N, Leal L, García-Algar O, Pacifici R. Pichini S, et al. Forensic Sci Int. 2014 Dec;245:e33-5. doi: 10.1016/j.forsciint.2014.10.027. Epub 2014 Oct 24. Forensic Sci Int. 2014. PMID: 25453781
For the first time we present a case of a neonatal withdrawal syndrome in a baby born to a woman who was a chronic consumer of 4-methylethcathinone. The newborn presented with increased jitteriness and irritability, highpitched cry, hypertonia in the limbs and brisk …
For the first time we present a case of a neonatal withdrawal syndrome in a baby born to a woman who was a chronic consumer of 4-m …
56 results